Study on Pharmacodynamic Material Basis and Molecular Mechanism of Wutou Tang in Pain Relief Based on Computer Simulation by Chunsong ZHENG, Jie LIN, Changlong FU, Jinxia YE, Xiaojie XU, Hongzhi YE

“…Objective: To explore pharmacodynamic material basis and molecular mechanism of Wutou Tang in pain relief. …”
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Pharmacodynamic Modeling of Warfarin Dosing Algorithm for Cardiovascular Patients in Indonesia: A Tailored Method to Anticoagulation Therapy by Putriana NA, Latarissa IR, Rusdiana T, Rostinawati T, Akbar MR

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Mechanism and Pharmacodynamic Substance Basis of Raw and Wine-Processed Evodia rutaecarpa on Smooth Muscle Cells of Dysmenorrhea Mice by Yeqian Liu, Hong Li, Lei Chen, Hongxia Zhao, Jian Liu, Shan Gong, Danfeng Ma, Chunming Chen, Shuiqing Zeng, Hongping Long, Weiqiong Ren

“…This research aimed to investigate the mechanism and pharmacodynamic substance basis of raw ER and PER on smooth muscle cells of dysmenorrhea mice. …”
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The influence of the pharmacodynamic properties of drugs on indications for their use: Sodium-glucose cotransporter 2 inhibitors (SGLT2 inhibitors) by Denda Nikola I., Maletin Nemanja Z., Atanasković Marko B., Vučković Biljana A., Rašković Aleksandar L.

“…This study aims to explore the pharmacodynamic advantages of SGLT2 inhibitors, expanding their therapeutic indications and assessing variations in pharmacological effects among different representatives. …”
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The Effect of Exercise on Pharmacodynamics and Pharmacokinetics of a Single Dose of Unfractionated Heparin—A Randomized, Controlled, Crossover Study by Liva K. Stuhr, Joshua B. Feinberg, Thea Christoffersen, Konstantinos Dimopoulos, Mikkel B. Christensen, David P. Sonne, Troels Riis, Peter S. Plomgaard, Jens P. Goetze, Emil L. Larsen, Kristian Karstoft

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Quantitative pharmacodynamics functional evaluation of Chinese medicine Qizhu formula in mice with dynamic near-infrared photoacoustic imaging by Qing-Juan Wu, Lan-Yu Chen, Quan-Mei Sun, Ning Wang, Dong Han, Wen-Liang Lv

“…The non-invasive NIR-PAI kinetic model shows potential in liver function detection and pharmacodynamic evaluation.…”
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Formulation development and evaluation, in silico PBPK modeling and in vivo pharmacodynamic studies of clozapine matrix type transdermal patches by Abdul Qadir, Syed Umer Jan, Muhammad Harris Shoaib, Muhammad Sikandar, Rabia Ismail Yousuf, Fatima Ramzan Ali, Fahad Siddiqui, Abdul Jabbar Magsi, Ghulam Mustafa, Muhammad Talha Saleem, Shafi Mohammad, Mohammad Younis, Muhammad Arsalan

“…The optimized patch was further evaluated for skin irritation, in vivo pharmacodynamics, in silico prediction, and simulation using the GastroPlus TCAT® model and stability. …”
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Pharmacodynamics of Qingxuan Jiangya Decoction on Blood Pressure Control and Suppression of Cardiac and Renal Vascular Injury in Spontaneously Hypertensive Rats by Hongwei CHEN, Liya BAO, Yue HUANG, Aling SHEN, Jun PENG, Jianfeng CHU

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Population Pharmacokinetic–Pharmacodynamic Modeling of Granulocyte Colony‐Stimulating Factor to Optimize Dosing and Timing for CD34+ Cell Harvesting by Xu Jiang, Jun Seok Cha, Byung Hak Jin, Choon Ok Kim, Dongwoo Chae

Subjects: “…population pharmacokinetic‐pharmacodynamic modeling…”
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Endoperoxides as Antimalarials: Development, Structural Diversity, and Pharmacodynamic Aspects of 1,2,4,5-Tetraoxane-Based Structural Scaffolds by Upendra Kumar Patel, Alka Alka, Alka Agarwal

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Kinetic-pharmacodynamic model to predict post-rituximab B-cell repletion as a predictor of relapse in pediatric idiopathic nephrotic syndrome by Ziwei Li, Qian Shen, Hong Xu, Zhiping Li

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Pharmacokinetic/pharmacodynamic analysis of tedizolid phosphate against Staphylococcus aureus and Streptococcus pneumoniae in children, adolescents, and adults by Monte Carlo simulation by Xiao-Chen Wei, Ming-Feng Zhao, Hai-Rong Lv, Xia Xiao

Subjects: “…Pharmacokinetics/pharmacodynamics…”
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Rationale and design of a prospective study evaluating population pharmacokinetics and pharmacodynamics of rivaroxaban in Chinese patients with non-valvular atrial fibrillation by Ming-Ming Yan, Xiao-Qin Liu, Yu-Fei Zhang, Hong-Yan Ding, Ming-Kang Zhong, Chun-Lai Ma

“…Few studies have investigated the pharmacokinetics (PK) and pharmacodynamics (PD) of rivaroxaban in Chinese patients and provided a solid reference for dose selection and individualised therapy.Methods and analysis This is a single-centre prospective study. …”
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Reveal the pharmacodynamic substances and mechanism of an edible medicinal plant Rhodiola crenulate in DSS-induced colitis through plasma pharmacochemistry and metabolomics by Yu Peng, Xiaoao Xiao, Tingting Ji, Xinyuan Wang, Yixuan Xu, Jianbo Xiao, Hui Cao, Zhiyong Chen, Huifan Liu, Yuanqing Gao, Hongxun Tao

“…Thus, the current research aims to reveal the pharmacodynamic material basis of RCE, as well as its mechanism against colitis. …”
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A Pharmacokinetic/Pharmacodynamic Study of Esomeprazole Comparing a Dual Delayed-Release Formulation (YYD601) to a Conventional Formulation Following Multiple Administrations in Healthy Adult Subjects by Lee HW, Kang WY, Park JS, Lee JH, Park JJ, Gwon MR, Yoon YR, Seong SJ

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Adaptation of an in vitro one-compartment pharmacodynamic chemostat for testing efficacy of ceftazidime against Burkholderia pseudomallei outside a BSL3 facility by Hana Farizah Zamri, Mohammad Ridhuan Mohd Ali, Ahmad Izzan Irfan Sha'ari, Nurul Husna Mohd Mazalan, Norazah Ahmad, Nur Asyura Nor Amdan, Nusaibah Abdul Rahim, Zakuan Zainy Deris

“…Non-clinical pharmacokinetic-pharmacodynamic (PKPD) models are crucial in the initial design of drug-dosage regimens and in drug development but has rarely been employed for testing high-risk organisms due to stringent handling procedures. …”
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Unique pharmacological properties of etrasimod among S1P receptor modulators by Ibragim Gaidarov, H. Kiyomi Komori, Dariusz T. Stepniak, Karin Bruinsma, Huong Dang, Xiaohua Chen, Todd Anthony, Joel Gatlin, Lisa Karimi‐Naser, Anh‐Tuan Ton, Tim Indersmitten, Paul E. Miller, Andre Ghetti, Najah Abi‐Gerges, David Unett, Hussien Al‐Shamma, Christopher J. Rabbat, Catherine Crosby, John W. Adams

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A new strategy for pharmacodynamic substance screening and research on gut microbiota pathway mechanisms based on UPLC-Q-orbitrap-MS and 16S rRNA by Zhiying Yu, Tong Li, Jie Yang, Jianghua He, Weijiang Zhang, Siyuan Li, Yunpeng Qi, Yihui Yin, Ling Dong, Wenjuan Xu

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Modeling the endocrine control of vitellogenin production in female rainbow trout by Kaitlin Sundling, Gheorghe Craciun, Irvin Schultz, Sharon Hook, James Nagler, Tim Cavileer, Joseph Verducci, Yushi Liu, Jonghan Kim, William Hayton

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Pimobendan oral solution is bioequivalent to pimobendan chewable tablets in beagle dogs by Olaf Kuhlmann, Michael Markert

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