The Proapoptotic Effect of MB-653 Is Associated with the Modulation of Metastasis and Invasiveness-Related Signalling Pathways in Human Colorectal Cancer Cells by Libor Sokoli, Peter Takáč, Mariana Budovská, Radka Michalková, Martin Kello, Natália Nosálová, Ľudmila Balážová, Šimon Salanci, Ján Mojžiš

Get full text

Synthesis, crystal structure, hirshfeld study, DFT analysis, molecular docking study, antimicrobial activity of β-enaminonitrile bearing 1H-pyran by Al-Anood M. Al-Dies, Fawzia F. Alblewi, Rawda M. Okasha, Mosa H. Alsehli, Rita M. A. Borik, Saleh Ihmaid, Abd El-Galil E. Amr, Hazem A. Ghabbour, Ahmed A. Elhenawy, Ahmed M. El-Agrody

Get full text

Evaluation of the Inhibitory Effect of Moringa oleifera Leaves Methanolic Extract against In Vitro Growth of Several Babesia Species and Theileria equi and the In Vivo Growth of Ba... by Mohamed Abdo Rizk, Shimaa Abd El-Salam El-Sayed, Mohamed Z. Sayed-Ahmed, Yosif Almoshari, Saad S. Alqahtani, Sarfaraz Ahmad, Nawazish Alam, Basma H. Marghani, Abdelbaset E. Abdelbaset, Ikuo Igarashi

Get full text

The relationship between HYDIN and fallopian tubal cilia loss in patients with epithelial ovarian cancer by Yuanli Guo, Yuanli Guo, Xinxin He, Junfeng Liu, Yanming Tan, Chao Zhang, Shan Chen, Shan Chen, Sheng Zhang

Get full text

Prevalence and clinical impact of disseminated intravascular coagulation in acute aortic dissection: a nationwide cohort study by Shuhei Murao, Yutaka Umemura, Hirotaka Mori, Yoshinobu Seki, Takayuki Ikezoe, Kohji Okamoto, Satoshi Fujimi, Kazuma Yamakawa

Get full text

Malaria and Helminth Coinfection among Children at the Douala Gyneco-Obstetric and Pediatric Hospital by Ashungafack Flavio, Yamssi Cedric, Noumedem Anangmo Christelle Nadia, Vincent Khan Payne

Get full text

Drug Use Evaluation of Beta-Blockers in Medical Wards of Nedjo General Hospital, Western Ethiopia by Ginenus Fekadu, Firomsa Bekele, Kumera Bekele, Sagni Hanbisa, Gemechis Belay, Mudasir Maqbool

Get full text

Synthesis and Characterization of Green Zinc Oxide Nanoparticles with Antiproliferative Effects through Apoptosis Induction and MicroRNA Modulation in Breast Cancer Cells by Amir Hossein Aalami, Mohammad Mesgari, Amirhossein Sahebkar

Get full text

Herbal supplements in Jordan: a cross-sectional survey of pharmacists’ perspectives and knowledge by Abdallah Y Naser, Michael Heinrich, Banaz Jalil, Jose M Prieto

Get full text

Quzhou Aurantii Fructus Flavonoids Ameliorate Inflammatory Responses, Intestinal Barrier Dysfunction in DSS-Induced Colitis by Modulating PI3K/AKT Signaling Pathway and Gut Microbi... by Wang H, Huang W, Pan X, Tian M, Chen J, Liu X, Li Q, Qi J, Ye Y, Gao L

“…Haiou Wang,1 Wenkang Huang,1 Xiaoya Pan,1 Meizi Tian,1 Jiahui Chen,1 Xiaotong Liu,1 Qin Li,1 Jianhua Qi,2 Yiping Ye,1 Lijuan Gao1 1School of Pharmacy, Hangzhou Medical College, Hangzhou, 310013, People’s Republic of China; 2College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, People’s Republic of ChinaCorrespondence: Lijuan Gao; Yiping Ye, Hangzhou Medical College, 182 Tianmushan Road, Hangzhou, Zhejiang, 310013, People’s Republic of China, Email gaolijuan04141002@126.com; yeyiping2005@163.comPurpose: To explore the protective effect and underlying mechanism of Quzhou Aurantii Fructus flavonoids (QAFF) on Ulcerative colitis (UC).Methods: The constituents of QAFF were accurately determined by ultra-performance liquid chromatography-tandem mass spectrometry (UPLC-MS/MS). …”
Get full text

Scutellarein Inhibits Osteosarcoma Growth by Targeting the TLR4/TRAF6/NF-κB Pathway by Shi Y, Tang Y, Sun Z, Sui P, Shao Y, Wang Z, Zhang J, Gao M

“…Yingxu Shi,1 Yu Tang,2 Zhiwei Sun,3 Ping Sui,4 Yiming Shao,4 Zhonghao Wang,4 Jian Zhang,1 Ming Gao1 1Department of Trauma Orthopedics, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272007, People’s Republic of China; 2Pharmaceutical Department, Affiliated Hospital of Jining Medical University, Jining, Shandong, 272007, People’s Republic of China; 3Department of Surgery, University of Colorado Anschutz Medical Campus, Aurora, CO, 80045, USA; 4Department of Clinical Medicine, Jining Medical University, Jining, Shandong, 272067, People’s Republic of ChinaCorrespondence: Ming Gao, Department of Trauma Orthopedics, Affiliated Hospital of Jining Medical University, No. 129 hehua Road, Jining, Shandong, 272007, People’s Republic of China, Tel + 86-0537-0298202, Email gaoming3661@mail.jnmc.edu.cnPurpose: Osteosarcoma (OS) is the most common malignant tumor associated with poor patient outcomes and a limited availability of therapeutic agents. …”
Get full text

Examining the Prevalence and Associated Factors of Sexually Transmitted Infections in People Living With HIV/AIDS at a Community Health Center in Bandung City, Indonesia by Nuraeni S, Alfian SD, Puspitasari IM

“…Sani Nuraeni,1,* Sofa Dewi Alfian,2,3 Irma Melyani Puspitasari2,3,* 1Master of Pharmacy Program, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 2Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia; 3Center of Excellence for Pharmaceutical Care Innovation (PHARCI), Universitas Padjajdjaran, Sumedang, Indonesia*These authors contributed equally to this workCorrespondence: Irma Melyani Puspitasari, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia, Tel +62 22 84288888 Ext 3510, Email irma.melyani@unpad.ac.idPurpose: This study aims to investigate the prevalence of sexually transmitted infections (STIs) and associated factors among people living with human immunodeficiency virus (HIV)/acquired immune deficiency syndrome (AIDS) (PLWHA) registered in a community health center (CHC) with HIV/AIDS support and treatment services in Indonesia.Methods: A cross-sectional study that included all PLWHA data from medical records registered in a CHC with HIV/AIDS support and treatment services was conducted in Bandung City, Indonesia, between March 2019 and March 2024. …”
Get full text

Chemical Profiling and Biological Activities on Nepalese Medicinal Plant Extracts and Isolation of Active Fraction of Nyctanthes arbor-tristis by Anita Khadka, Akash Budha Magar, Khaga Raj Sharma

“…The importance of medicinal plants for the treatment of different diseases is high from the aspects of the pharmaceutical industry and traditional healers. The present study involves nine different medicinal plants, namely, Neolamarckia cadamba, Nyctanthes arbor-tristis, Pogostemon benghalensis, Equisetum debile, Litsea monopetala, Spilanthes uliginosa, Desmostachya bipinnata, Mallotus philippensis, and Phoenix humilis, collected from Chitwan district of Nepal for biochemical analysis followed by the isolation of active plant fractions from the bioactive plant extract. …”
Get full text

Efficacy of Probiotic Supplements and Topical Applications in the Treatment of Acne: A Scoping Review of Current Results by Sutema IAMP, Latarissa IR, Widowati IGAR, Sartika CR, Ciptasari NWE, Lestari K

“…Ngoerah Central General Hospital, Denpasar, Indonesia; 6Center of Excellence for Pharmaceutical Care Innovation, Universitas Padjadjaran, Sumedang, IndonesiaCorrespondence: Keri Lestari, Department of Pharmacology and Clinical Pharmacy, Faculty of Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia, Email lestarikd@unpad.ac.idAbstract: Acne vulgaris is a prevalent dermatological condition characterized by comedones, papules, and pustules, with significant physical and psychological implications. …”
Get full text

Long-term results of irritable bowel syndrome treatment by A. I. Ulyanin, Yu. M. Poluektov, Ye. A. Poluektova, Ch. S. Pavlov, V. T. Ivashkin

“…In 30 days secession of pharmaceutical therapy 73.3% of patients with IBS-D who received probiotic therapy during relapse maintained clinical remission, 75% of patients often motility regulator treatment and 60% of those who received antispasmodic medications. …”
Get full text

Design and Kinematics Analysis of a 3-DOF Translational Parallel Mechanism by Yu Liang, Zhang Long, Wang Peng, Wan Jun

“…A systemic research on configuration design and kinematics analysis of a new 3-DOF translational parallel robot， Delta， which involved T-type hinges， is carried out based on Delta widely used in food fields， pharmaceutical fields， electronic fields and other light industry. …”
Get full text

Maintenance of visual functions in patients with a scheduled cataract surgery by I.A. Il’inskaya, S.Yu. Kopaev

“…</i> </p> <p> <i><b>Conclusion</b>: Catalin^® (Senju Pharmaceutical) is effective in early cataract. In immature cataract, this drug slows down refractive changes. …”
Get full text

THC degradation does not impair the accuracy of THC doses aerosolized by the metered-dose SyqeAir inhaler: a 24-month stability trial by Joshua Aviram, Daniella Atzmony, Anna Frenklakh, Asaf Kroll, Ilana Zaks, Arno Hazekamp

“…Despite the significant change of relative cannabinoid composition within the cartridge, the actual THC dose present in the aerosol remained relatively stable throughout this period and within the dosage range of 500mcg±25% required for pharmaceutical-grade inhalers. Conclusions MC powder in Syqe cartridges may be stored at room temperature for at least 2 years after production without affecting the aerosolized THC dose delivered to patients by more than ±25%. …”
Get full text

Penerapan Model Enterprise Architecture Cube Pada Perencanaan Strategi Sistem Dan Teknologi Informasi by Delia Apriana, Sawali Wahyu

“…Abstrack   Afdhal Pharmacy is an enterprise engaged in the pharmaceutical sector as a drug provider. In carrying out its business processes there are problems at Afdhal Pharmacy, namely ordering goods to suppliers still relying on bookkeeping for recording goods data resulting in errors in goods data collection such as lagging data on goods that should be recorded and delays in ordering goods. …”
Get full text

Presenting a Leadership Empowerment Model through Sense-making by Using the Cognitive and Behavioral Scripts by Hamid Zare, Aliasghar Pourezzat, Hasan Zareei Matin, Arezoo Salmani

“…In this extensive study, a total of 111 randomly selected groups operating at various organizational levels within companies active in the pharmaceutical industry were meticulously examined to gather a broad spectrum of insights. …”
Get full text