Older People's Perceptions of Well-Being by I.V. Vasileva, M.V. Chumakov

“…The semantic groups “values", “existence”, “success” belong to the peripheral zone of ideas. In the semantic group “emotions” in the structure of ideas about well-being in elderly people, emotions of greater intensity prevail over emotions of lesser intensity. …”
Get full text

Antinociceptive Activity of Ethanol Extract from Duguetia chrysocarpa Maas (Annonaceae) by Jackson Roberto Guedes da Silva Almeida, Edigênia Cavalcante da Cruz Araújo, Luciano Augusto de Araújo Ribeiro, Julianeli Tolentino de Lima, Xirley Pereira Nunes, Ana Sílvia Suassuna Carneiro Lúcio, Maria de Fátima Agra, José Maria Barbosa Filho

“…The data obtained suggest that the antinociceptive effect of the extract may be mediated via both peripheral and central mechanisms. The phytochemical investigation yielded the isolation of the benzenoid derivative 3-methoxy-4-ethoxy benzoic acid which is being reported for the first time in this genus.…”
Get full text

LEACH-D: A low-energy, low-delay data transmission method for industrial internet of things wireless sensors by Desheng Liu, Chen Liang, Hongwei Mo, Xiaowei Chen, Dequan Kong, Peng Chen

“…Within IoT-based systems, wireless sensor networks (WSNs) have emerged as a crucial method for collecting peripheral environmental data within industries, owing to their self-organizational attributes. …”
Get full text

Electrophysiological properties of vestibular hair cells isolated from human crista by Nesrien Mohamed, Mohammad Al-Amin, Frances L. Meredith, Olivia Kalmanson, Anna Dondzillo, Stephen Cass, Samuel Gubbels, Katherine J. Rennie

“…Rapid access to surgically obtained adult human vestibular neuroepithelia allows translational studies crucial for improved understanding of human peripheral vestibular function.…”
Get full text

The Utility of Point of Care Test for Soluble ST2 in Predicting Adverse Cardiac Events during Acute Care of ST-Segment Elevation Myocardial Infarction by Anggoro Budi Hartopo, Indah Sukmasari, Ira Puspitawati

“…Soluble ST2 level was measured from peripheral blood taken on admission with POCT. Observation during acute intensive care was conducted to record adverse cardiac events. …”
Get full text

Neutrophil membrane biomimetic delivery system (Ptdser‐NM‐Lipo/Fer‐1) designed for targeting atherosclerosis therapy by Wei Li, Chang Liu, Sichuan Wang, Naifeng Liu

“…Abstract Atherosclerosis is a progressive inflammatory disease characterised by excessive lipid accumulation and inflammatory cell infiltration and is the basis of most cardiovascular diseases and peripheral arterial diseases. Therefore, an effectively targeted delivery system is urgently needed to deliver ferroptosis‐specific inhibitors to the site of arterial plaque and the inflammatory microenvironment. …”
Get full text

Fibrous Dysplasia of the Ethmoid Bone Diagnosed in a 10-Year-Old Patient by Zofia Resler, Monika Morawska-Kochman, Katarzyna Resler, Tomasz Zatoński

“…The tumor causes bone defects in the area of the nasal bone, leading to fluid retention in the peripheral parts of the right maxillary sinus. The patient’s parents decided not to undergo surgery to remove the diseased tissue and reconstruct the area, as it would be very extensive, risky, and disfiguring. …”
Get full text

Hepatitis D virus infection triggers CXCL9-11 upregulation in hepatocytes and liver infiltration of CXCR3+ CD4 T cells by Jan-Hendrik Bockmann, Lena Allweiss, Annika Volmari, David da Fonseca Araújo, Matin Kohsar, Anastasia Hyrina, Janine Kah, Zhijuan Song, Josolyn Chan, Katja Giersch, Tassilo Volz, Marc Lütgehetmann, Jeffrey J. Wallin, Dmitry Manuilov, Meghan M. Holdorf, Simon P. Fletcher, Ansgar W. Lohse, Antonio Bertoletti, Julian Schulze zur Wiesch, Maura Dandri

“…The corresponding chemokine receptor CXCR3 was found upregulated specifically on peripheral bulk CD4 T cells of patients with CHD. CXCR3 upregulation was unspecific and was not detected on HDAg- or HBsAg-specific CD4 T cells by activation-induced marker assay. …”
Get full text

Levels of Pathogenic Th17 and Th22 Cells in Patients with Rheumatoid Arthritis by Marlen Vitales-Noyola, Berenice Hernández-Castro, Diana Alvarado-Hernández, Lourdes Baranda, Sofía Bernal-Silva, Carlos Abud-Mendoza, Perla Niño-Moreno, Roberto González-Amaro

“…For this purpose, blood samples were obtained from 30 patients with RA and 16 healthy subjects, and the levels of Th17 and type 22 helper (Th22) lymphocytes were analyzed as well as the in vitro differentiation of peripheral blood mononuclear cells into Th17 lymphocytes induced by interleukin-23 (IL-23) and IL-1β. …”
Get full text

Neuroendocrine Alterations in Obese Patients with Sleep Apnea Syndrome by Fabio Lanfranco, Giovanna Motta, Marco Alessandro Minetto, Matteo Baldi, Marcella Balbo, Ezio Ghigo, Emanuela Arvat, Mauro Maccario

“…Obese patients with OSAS show a reduction of both spontaneous and stimulated growth hormone (GH) secretion coupled to reduced insulin-like growth factor-I (IGF-I) concentrations and impaired peripheral sensitivity to GH. Hypoxemia and chronic sleep fragmentation could affect the sleep-entrained prolactin (PRL) rhythm. …”
Get full text

Programmed neurite degeneration in human central nervous system neurons driven by changes in NAD+ metabolism by Markus Brüll, Selina Multrus, Michael Schäfer, Ivana Celardo, Christiaan Karreman, Marcel Leist

“…This process appeared specific, as isolated neurites maintained ATP levels and a coupled mitochondrial respiration for at least 6 h. In the peripheral nervous system (PNS) many studies observed that NAD+ metabolism, in particular by the NADase SARM1, plays a major role in the ND occurring after axotomy. …”
Get full text

Second-Hand Smoke Increases Bronchial Hyperreactivity and Eosinophilia in a Murine Model of Allergic Aspergillosis by Brian W. P. Seymour, Edward S. Schelegle, Kent E. Pinkerton, Kathleen E. Friebertshauser, Janice L. Peake, Viswanath P. Kurup, Robert L. Coffman, Laurel J. Gershwin

“…Immunological data that supports this exacerbation of airway hyperresponsiveness being mediated by an enhanced type 1 hypersensitivity response include: eosinophilia in peripheral blood and lung sections. All Af sensitized mice produced elevated levels of IL4, IL5 and IL10 but no IFN-γ indicating a polarized Th2 response. …”
Get full text

Lung-Derived Mediators Induce Cytokine Production in Downstream Organs via an NF-κB-Dependent Mechanism by E. K. Patterson, L. J. Yao, N. Ramic, J. F. Lewis, G. Cepinskas, L. McCaig, R. A. W. Veldhuizen, C. M. Yamashita

“…We hypothesized that lung-derived mediators generated by mechanical ventilation (MV) are amplified by peripheral organs in a “feed forward” mechanism of systemic inflammation. …”
Get full text

Adipose-Derived Stem Cells Alleviate Radiation-Induced Muscular Fibrosis by Suppressing the Expression of TGF-β1 by Wei Sun, Xinchu Ni, Suping Sun, Leiming Cai, Jingping Yu, Jian Wang, Bin Nie, Zhiqiang Sun, Xinye Ni, Xiufeng Cao

“…Migration of ASCs was observed in the peripheral tissues along the needle passage in the injured muscle. …”
Get full text

Role of Platelet-Rich Plasma in Spinal Fusion Surgery: Systematic Review and Meta-Analysis by Daudi R. Manini, Frank D. Shega, ChaoFeng Guo, YuXiang Wang

“…PRP facilitates new bone formation and bone fusion with a minimum concentration of the growth factor 5 times that of the peripheral blood. PRP stimulatory effects are not continuous and are very effective within six months of implantation.…”
Get full text

Transthyretin-Related Familial Amyloidosis Polyneuropathy with Spinal Cord Damage: A Case Report by Liu H, Huang C, Du Y, Liu J, Ren X, Wang H, Ye J, Zhou H, Duan Z

“…The disease is characterized primarily by peripheral and autonomic nerve damage. Disease progression is associated with frequent involvement of the heart, lungs, kidneys, eyes, and other organs. …”
Get full text

Comparison of PM2.5 Chemical Compositions during Haze and Non-haze Days in a Heavy Industrial City in North China by Menghui Li, Liping Wu, Xiangyan Zhang, Xinwu Wang, Wenyu Bai, Jing Ming, Chunmei Geng, Wen Yang

“…The haze episode was caused by a combination of unfavorable meteorological conditions, secondary formation, the accumulation of local pollutants, and peripheral transmission.…”
Get full text

Study protocol for a hybrid type 3 effectiveness-implementation trial of a team-based implementation strategy to support educators’ use of a social engagement intervention by Jill Locke, Aksheya Sridhar, Wendy Shih, Stephanie Shire, Andria B. Eisman, Emily Kim, Adora Du, Christine Espeland, Connie Kasari

“…This protocol paper describes a multi-site study that will test whether an educator-level implementation strategy, coaching, with or without a school-level implementation strategy, school-based teams, will maximize educators’ use (fidelity and sustainment) of RR for autistic students and their peers who are socially-isolated, rejected, or peripheral and may need additional support during recess. …”
Get full text

Specific Antibody Production by Blood B Cells is Retained in Late Stage Drug-naïve HIV-infected Africans by Lydie Béniguel, Evelyne Bégaud, Fabrice Cognasse, Philippe Gabrié, Christophe D. Mbolidi, Mary A. Marovich, Céline Cazorla, Frédéric Lucht, Christian Genin, Olivier Garraud

“…Unseparated peripheral blood mononuclear cells (PBMCs) obtained from drug-naïve African individuals living in a context of multi-infections and presenting with high viral load (VL), were cultured in vitro and tested for their ability to produce antibodies (Abs) reacting with HIV-1 antigens. …”
Get full text

Understanding Autoimmune Mechanisms in Multiple Sclerosis Using Gene Expression Microarrays: Treatment Effect and Cytokine-related Pathways by A. Achiron, M. Gurevich, D. Magalashvili, I. Kishner, M. Dolev, M. Mandel

“…We have applied gene expression microarrays technology in peripheral blood mononuclear cells (PBMC) to better understand MS pathogenesis and better target treatment approaches. …”
Get full text