Bone Marrow-Liver-Spleen Type of Large B-Cell Lymphoma Associated with Hemophagocytic Syndrome: A Rare Aggressive Extranodal Lymphoma by Kirill A. Lyapichev, Jennifer R. Chapman, Oleksii Iakymenko, Offiong F. Ikpatt, Uygar Teomete, Sandra Patricia Sanchez, Francisco Vega

“…Circulating lymphoma cells were not seen in the peripheral blood smears. The patient underwent treatment with chemotherapy (R-CHOP) but unfortunately passed away 2 months after initial presentation. …”
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Clinical outcomes and anti-inflammatory mechanisms predict maximum heart rate improvement after physical activity training in individuals with psychiatric disorders and comorbid ob... by Pau Soldevila-Matías, Joan Vicent Sánchez-Ortí, Patricia Correa-Ghisays, Vicent Balanzá-Martínez, Gabriel Selva-Vera, Roberto Sanchis-Sanchis, Néstor Iglesias-García, Manuel Monfort-Pañego, Pilar Tomás-Martínez, Víctor M Victor, Benedicto Crespo-Facorro, Constanza San Martin Valenzuela, José Antonio Climent-Sánchez, Rosana Corral-Márquez, Inmaculada Fuentes-Durá, Rafael Tabarés-Seisdedos

“…<h4>Methods</h4>Patients with major depressive disorder, bipolar disorder and, schizophrenia and with comorbid obesity (n = 29) were assigned to a 12-week structured physical exercise program. Peripheral blood biomarkers of inflammation, oxidative stress, vascular mechanisms, and metabolic activity, as well as neurocognitive and functional performance were assessed twice, before and after intervention. …”
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Genetic proxies for clinical traits are associated with increased risk of severe COVID-19 by N. J. M. Chaddock, S. S. R. Crossfield, M. Pujades-Rodriguez, M. M. Iles, A. W. Morgan

“…In univariate analyses, 17 PRS were associated with increased risk of severe COVID-19 and, of these, four remained associated with COVID-19 outcomes following adjustment for sociodemographic/clinical variables: hypertension PRS (OR = 1.1, 95%CI 1.03–1.18), atrial fibrillation PRS (OR = 1.12, 95%CI 1.03–1.22), peripheral vascular disease PRS (OR = 0.9, 95%CI 0.82–0.99), and Alzheimer’s disease PRS (OR = 1.14, 95%CI 1.05–1.25). …”
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USING INFRARED THERMOGRAPHIC TECHNIQUE AS AN ALTERNATIVE TO CONVENTIONAL RECTAL THERMOMETER IN SHEEP by Nizar J. Hussein, Rekesh S. Habib, Fatah M. Khalaf, Rana M. Fazal, Muhammad Owais

“…At the same time, the peripheral temperatures were measured from the ears, muzzle (MUZ), inner thigh (IT), inguinal region (ING), rectum, vulva, and five areas of the eyes, including nasal conjunctiva (NC), nasal limbus (NL), center cornea (CC), temporal limbus (TL), and temporal conjunctiva (TC) using IR thermometer and IR camera. …”
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Correlation between invasive and noninvasive oxygen indices in critically ill COVID patients with ARDS: A retrospective analysis by Arin Choudhury, Meena Singh, Amandeep Jaswal, Saurav Mitra Mustafi, Santvana Kohli

“…Objective: This study aims to evaluate the correlation between peripheral oxygen saturation/fraction of inspired oxygen (SpO2/FiO2) and arterial partial pressure of oxygen (PaO2)/FiO2 ratio in the diagnosis and assessment of severity in acute respiratory distress syndrome (ARDS) patients admitted to intensive care unit (ICU) during the SARS-CoV-2 outbreak. …”
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Was Grand Duchy of Lithuania a Federation? by Zenonas Norkus

“…However, GDL was transformed into a federation only on the eve of the Lublin Union in 1569, while in the XIV-first half of the XVI century it was a traditional empire, including metropolitan military agrarian domains and indirectly ruled peripheral areas shading into areas of mere hegemony.   …”
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Biomarker discovery and phytochemical interventions in Alzheimer's disease: A path to therapeutic advances by Mithila Debnath, Mahir Azmal, Rashid Taqui, Moshiul Alam Mishu, Ajit Ghosh

“…Methods: A differential expression analysis was conducted using GEO2R, where the significant differentially expressed genes (DEGs) were identified in brain areas that include the Entorhinal Cortex (EC) and Posterior Cingulate (PC), as well as in peripheral blood. The interactions between DEGs and phytochemicals were investigated using computational approaches that involve molecular docking and molecular dynamic simulations. …”
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Vestibular patients generate more regular head movements than healthy individuals during gaze-stabilization exercises by Cecelia Shuai, Omid A. Zobeiri, Jennifer L. Millar, Michael C. Schubert, Mark Shelhamer, Kathleen E. Cullen

“…Abstract The vestibular system is vital for maintaining stable vision during daily activities. When peripheral vestibular input is lost, patients initially experience impaired gaze stability due to reduced effectiveness of the vestibular-ocular-reflex pathway. …”
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Differential gene expression during recall of behaviorally conditioned immune enhancement in rats: a pilot study [version 3; peer review: 1 approved, 3 approved with reservations] by Marcus Picard-Mareau, Markus Rueckels

“…Background Behaviorally conditioned immune functions are suggested to be regulated by bidirectional interactions between CNS and peripheral immune system via the hypothalamic-pituitary-adrenal (HPA) axis, sympathetic nervous system (SNS), and the parasympathetic nervous system (PNS). …”
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Impact of Inherited Prothrombotic Disorders on the Long-Term Clinical Outcome of Percutaneous Transluminal Angioplasty in Patients with Diabetes by Michal Dubský, Alexandra Jirkovská, Libuše Pagáčová, Robert Bém, Andrea Němcová, Vladimíra Fejfarová, Veronika Wosková, Edward B. Jude

“…Diabetic patients with peripheral arterial disease (PAD) treated by PTA in our centre between 2008 and 2011 were included in the study. …”
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GPS Trajectory-Based Spatio-Temporal Variations of Traffic Accessibility under Public Health Emergency Consideration by Luqi Dong, Ying Lv, Huijun Sun, Danyue Zhi, Tingting Chen

“…At the same time, the peripheral areas show a trend of low-value aggregation. …”
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Wearable non-invasive neuroprosthesis for targeted sensory restoration in neuropathy by Noemi Gozzi, Lauren Chee, Ingrid Odermatt, Sanne Kikkert, Greta Preatoni, Giacomo Valle, Nikolai Pfender, Felix Beuschlein, Nicole Wenderoth, Carl Zipser, Stanisa Raspopovic

“…Abstract Peripheral neuropathy (PN), the most common complication of diabetes, leads to sensory loss and associated health issues as pain and increased fall risk. …”
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Video Games in Rehabilitation Programs for People with Parkinson’s Disease: A Systematic Review by Isabel Quirosa-Galán, Sara García-Bravo, Anthia Cristina Fabara-Rodríguez, Mª Pilar Rodríguez-Pérez, Elisabet Huertas-Hoyas, Jorge Pérez-Corrales, Gemma Fernández-Gómez, Madeleine Donovan, Cristina García-Bravo

“…Background: Parkinson’s disease is a neurodegenerative disorder affecting the central and peripheral nervous systems. Its treatment combines pharmacological and rehabilitative approaches, aimed at improving motor symptoms and preventing cognitive decline. …”
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Effects of continuous positive airway pressure treatment on arterial stiffness and inflammatory factors in patients with coronary heart disease complicated with obstructive sleep a... by Liang Wang, Yuanqi Wang, Tiantian Jiao, Linghao Xu, Endong Ji, Sakibur Rahman Tapu, Yehong Liu, Jiming Li

“…Method 59 patients with coronary heart disease complicated by moderate to severe sleep apnea were divided into a CPAP treatment group (CPAP + coronary heart disease standard treatment) and a control group (only coronary heart disease standard treatment). Peripheral blood test reports were collected and pulse wave velocity (PWV) measurements were performed for each patient at the beginning, 3 months, and 6 months of treatment. …”
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An Open‐Label Phase II Trial of Pembrolizumab, an Immune Checkpoint Inhibitor Alone or in Combination With Oral Azacitidine as Second‐Line Therapy for Advanced Head and Neck Squamo... by Vinod K. Ramani, Srimonta Gayen, Radheshyam Naik

“…Results In this trial, molecular profiling of tumor and peripheral blood samples will be conducted which will enable in gaining biological insights for survival benefit. …”
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The Shanghai Cooperation Organization after Enlargement: New Challenges and Prospects by D. V. Efremenko

“…This enlargement of the SCO implies a considerable increase in its political and economic weight, as well as additional interstate contradictions, which have previously had a peripheral significance for the SCO.In that regard special attention is drawn to the new political dynamics within the SCO. …”
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NPT1220-312, a TLR2/TLR9 Small Molecule Antagonist, Inhibits Pro-Inflammatory Signaling, Cytokine Release, and NLRP3 Inflammasome Activation by Agata Habas, Srinivasa Reddy Natala, Jon K. Bowden-Verhoek, Emily M. Stocking, Diana L. Price, Wolfgang Wrasidlo, Douglas W. Bonhaus, Martin B. Gill

“…Together, these findings suggest that blockade of TLR2 and TLR9 may reduce inappropriate production of pro-inflammatory cytokines and chemokines from peripheral and central immune cells and thus potentially provide therapeutic benefit in neuroinflammatory/neurodegenerative disorders.…”
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Neurobiological Changes Associated with Excess Weight: A Narrative Review by B Sharmila, Sovan Bagchi, Mohd Imran, Tamalika Chakraborty, K Pushpalatha

“…Early reviews have often overlooked the intricate relationship between obesity and brain function, focusing more on peripheral effects, such as cardiovascular and metabolic complications, while neglecting the specific effects on brain structure and function. …”
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T-Cell Large Granular Lymphocytic Leukemia with Extremely Rare Immunophenotype (CD4/CD8 Double-Positive) Followed by Multiple Myeloma Diagnosis by Dina Soliman, Sherin Sallam, Susanna Akiki, Deena Mudawi, Feryal Ibrahim

“…We report a case of asymptomatic CD4/CD8 double-positive T-LGLL. Flow cytometry on peripheral blood revealed a subpopulation of CD4/CD8 double-positive T cells expressing CD57 and cTIA. …”
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E-Selectin/AAV Gene Therapy Promotes Myogenesis and Skeletal Muscle Recovery in a Mouse Hindlimb Ischemia Model by Antoine J. Ribieras, Yulexi Y. Ortiz, Yan Li, Nga T. Le, Carlos T. Huerta, Francesca A. Voza, Hongwei Shao, Roberto I. Vazquez-Padron, Zhao-Jun Liu, Omaida C. Velazquez

“…The response to ischemia in peripheral artery disease (PAD) depends on compensatory neovascularization and coordination of tissue regeneration. …”
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