Intraoperative Optical Coherence Tomography Analysis of Clear Corneal Incision: Effect of the Lateral Stromal Hydration by Jiri Cendelin, Stepan Rusnak, Lenka Hecova

“…Hydration worsened the incision architecture in 14 cases (21.5%); most often, it induced/worsened posterior lip prominence (15.4%), less often posterior lip retraction (1.6%), tongue inversion into the incision (1.6%), gap development in the peripheral part of the corneal incision (1.6%), or incomplete opening of the corneal incision (1.6%). …”
Get full text

Mechanisms of Cancer-Induced Bone Pain by Wang X, Li L, Wang Y

“…Therefore, they may require dose increases, which can increase the severity of opioid-induced side effects, in turn influencing quality of life. The peripheral mechanisms of CIBP primarily involve bone tissue damage, tumor microenvironment formation, and changes in the dorsal root ganglion. …”
Get full text

Disruption of the Suprachiasmatic Nucleus Blunts a Time of Day-Dependent Variation in Systemic Anaphylactic Reaction in Mice by Yuki Nakamura, Kayoko Ishimaru, Yu Tahara, Shigenobu Shibata, Atsuhito Nakao

“…In mammals, the central clock located in the suprachiasmatic nucleus (SCN) of the hypothalamus synchronizes and entrains peripheral circadian clock present in virtually all cell types via neural and endocrine pathways, thereby driving the daily rhythms in behavior and physiology. …”
Get full text

The Emerging Roles of the Calcineurin-Nuclear Factor of Activated T-Lymphocytes Pathway in Nervous System Functions and Diseases by Maulilio John Kipanyula, Wahabu Hamisi Kimaro, Paul F. Seke Etet

“…Treatment with calcineurin/NFAT inhibitors induces some degree of neuroprotection and decreased reactive gliosis in the central and peripheral nervous system. In this paper, we summarize and discuss the current understanding of the roles of calcineurin/NFAT signaling in physiology and pathologies of the adult and developing nervous system, with an emphasis on recent reports and cutting-edge findings. …”
Get full text

p53 dosage can impede KrasG12D- and KrasQ61R-mediated tumorigenesis. by Özgün Le Roux, Jeffery I Everitt, Christopher M Counter

“…However, the incidence and grade of peripheral atypical alveolar hyperplasia was significantly decreased in both backgrounds with increased p53 dosage. …”
Get full text

The Effect of COVID-19 Pandemic on Emitted PM2.5 in Urban Road Networks: Using Loop Data and Kriging Method for Passenger Cars in the Central Part of the City of Lodz by Marta Borowska-Stefańska, Michał Kowalski, Paulina Kurzyk, Alireza Sahebgharani, Szymon Wiśniewski

“…Results show that before the pandemic, PM2.5 pollution was highly concentrated in the center and peripheral parts of the area under consideration, and it would gradually drop outside rush hours and grow at peak hours. …”
Get full text

Differential Fasting Plasma Glucose and Ketone Body Levels in GHRKO versus 3xTg-AD Mice: A Potential Contributor to Aging-Related Cognitive Status? by Chelsea M. Griffith, Lauren N. Macklin, Andrzej Bartke, Peter R. Patrylo

“…Since the majority of brain nutrients come from the periphery, this study examined whether the capacity to regulate peripheral glucose levels and KB production differs in animals with successful cognitive aging (growth hormone receptor knockouts, GHRKOs) versus unsuccessful cognitive aging (the 3xTg-AD mouse model of Alzheimer’s disease). …”
Get full text

Mothers’ experiences as legal guardian of children's phlebitis during hospitalization in Indonesia: A phenomenological study by Casman Casman, Dian Mahanani, Balbina Antonelda Marled Wawo, Muhammad Iqbal, Desy Rizki Ariani, Anung Ahadi Pradana

“…Background: Peripheral intravenous catheter (PIVC) insertion is a common procedure performed by nurses for hospitalized children, but phlebitis—an inflammation of the vein—is a frequent complication. …”
Get full text

What is the Difference Between the Different Types of Thermometers? by Işıl Kübra Savaş, Gülsüm İclal Bayhan

“…Conclusion: None of the peripheral measurement methods can accurately measure the core temperature. …”
Get full text

Rat Nasal Respiratory Mucosa-Derived Ectomesenchymal Stem Cells Differentiate into Schwann-Like Cells Promoting the Differentiation of PC12 Cells and Forming Myelin In Vitro by Jian Zhang, Xin Gao, Hongjun Zou, Jinbo Liu, Zhijian Zhang

“…Schwann cell (SC) transplantation as a cell-based therapy can enhance peripheral and central nerve repair experimentally, but it is limited by the donor site morbidity for clinical application. …”
Get full text

Comparing apples with apples: A proposed taxonomy for "Community Health Workers" and other front-line health workers for international comparisons. by Stephen Hodgins, Uta Lehmann, Henry Perry, Nicholas Leydon, Kerry Scott, Smisha Agarwal, Hannah Marcus, Rajani Ved, Elijah Olivas, Madeleine Ballard, Dickson Mbewe, Margaret Odera, Sherlie Petit Homme, Benard Otieno, Pasipano Wutete, Angeline Chikumba, Prossy Muyingo, John Kyakuha, Emmanuel Harcourt, Morseda Chowdhury, David Musoke, Thadee Niyoyitungira, Abimbola Olaniran, John Koku-Awoonor Williams, Lívia Milena Barbosa de Deus E Méllo, Romário Correia Dos Santos, Isabela Cardoso de Matos Pinto, Ram Shrestha, Salim Sadruddin, Melanie Morrow, Eric Sarriot, Maryse Kok, Bhanu Pratap

“…It also leads to a failure to consider occupational groups not commonly thought of as CHWs-but engaged in PHC service delivery at the most peripheral level-in community-based-PHC planning and management arrangements. …”
Get full text

Effect of Solid-to-Gas Ratio on Powder Fuel Mixing in a Cavity-Based Supersonic Combustion Chamber with Induced Shock: A Numerical Study by Zuodong Liang, Ming Jiang, Shaoqing Hu, Kai Ma, Guiyang Xu, Wenjie Wang, Yuezu Miao, Hongyan Li

“…The interaction between powder fuels and the peripheral rotating regions of these vortices significantly improves the mixing efficiency, with the highest average mixing efficiency increased by 30%. …”
Get full text

Neutrophil adhesion to vessel walls impairs pulmonary circulation in COVID-19 pathology by Hiroshi Ueki, I-Hsuan Wang, Maki Kiso, Kenta Horie, Shun Iida, Sohtaro Mine, Michiko Ujie, Hung-Wei Hsu, Chen-Hui Henry Wu, Masaki Imai, Tadaki Suzuki, Wataru Kamitani, Eiryo Kawakami, Yoshihiro Kawaoka

“…Re-analysis of scRNA-seq data from peripheral blood mononuclear cells from COVID-19 cases revealed increased expression levels of CD44 and SELL in neutrophils in severe COVID-19 cases compared to a healthy group, consistent with our observations in the mouse model. …”
Get full text

Distribution of Adiponectin Receptors 1 and 2 in the Rat Olfactory Bulb and the Effect of Adiponectin Injection on Insulin Receptor Expression by Alfredo Miranda-Martínez, Octavio Fabián Mercado-Gómez, Virginia Arriaga-Ávila, Rosalinda Guevara-Guzmán

“…Adiponectin (APN) is an adipocyte-derived hormone that has peripheral beneficial effects. Although its receptors AdipoR1 and AdipoR2 are expressed in the brain, their function in neurons is poorly understood. …”
Get full text

Nitric Oxide - Its Importance in Swallowing, Inflammatory Bowel Disease and Cirrhotic Cardiomyopathy by ABR Thomson

“…Nitric oxide is a neurotransmitter found in the central and peripheral nervous systems. Nitric oxide synthase (NOS) is localized in the central nervous system, including the nucleus of the solitary tract, nucleus ambiguus and dorsal motor nucleus of the vagus. …”
Get full text

Eosinophils: old cells, new directions by Alejandra Sanchez Santos, Iovanna Socorro Avila, Helena Galvan Fernandez, Sara Cazorla Rivero, Sara Cazorla Rivero, Angelina Lemes Castellano, Carlos Cabrera Lopez

“…Most of this research has been conducted in murine models, but several studies confirm these findings in peripheral blood and tissue. The objective of this review is to provide a comprehensive analysis of eosinophils, by recent findings that divide this cell line into two distinct populations with different functions and purposes.…”
Get full text

Optimal sigmoid function models for analysis of transspinal evoked potential recruitment curves recorded from different muscles. by Andreas Skiadopoulos, Maria Knikou

“…Recruitment input-output curves of transspinal evoked potentials that represent the net output of spinal neuronal networks during which cortical, spinal and peripheral inputs are integrated as well as motor evoked potentials and H-reflexes are used extensively in research as neurophysiological biomarkers to establish physiological or pathological motor behavior and post-treatment recovery. …”
Get full text

Autologous Stem Cell Therapy in Critical Limb Ischemia: A Meta-Analysis of Randomized Controlled Trials by Baocheng Xie, Houlong Luo, Yusheng Zhang, Qinghui Wang, Chenhui Zhou, Daohua Xu

“…Critical limb ischemia (CLI) is the most dangerous stage of peripheral artery disease (PAD). Many basic researches and clinical treatment had been focused on stem cell transplantation for CLI. …”
Get full text

Modulation of Tyrosine Hydroxylase, Neuropeptide Y, Glutamate, and Substance P in Ganglia and Brain Areas Involved in Cardiovascular Control after Chronic Exposure to Nicotine by Merari F. R. Ferrari, Emerson F. Coelho, Karen L. G. Farizatto, Gerson Chadi, Debora R. Fior-Chadi

“…Considering that nicotine instantly interacts with central and peripheral nervous systems promoting cardiovascular effects after tobacco smoking, we evaluated the modulation of glutamate, tyrosine hydroxylase (TH), neuropeptide Y (NPY), and substance P (SP) in nodose/petrosal and superior cervical ganglia, as well as TH and NPY in nucleus tractus solitarii (NTS) and hypothalamic paraventricular nucleus (PVN) of normotensive Wistar Kyoto (WKY) and spontaneously hypertensive rats (SHR) after 8 weeks of nicotine exposure. …”
Get full text

Phase I Study of Anti-CD3 x Anti-Her2 Bispecific Antibody in Metastatic Castrate Resistant Prostate Cancer Patients by Ulka Vaishampayan, Archana Thakur, Ritesh Rathore, Nicola Kouttab, Lawrence G. Lum

“…Immune evaluations of peripheral blood mononuclear cells in 2 patients before and after immunotherapy showed increases in IFN-γ EliSpot responses and Th1 serum cytokines. …”
Get full text