Mechanisms and Emerging Regulators of Neuroinflammation: Exploring New Therapeutic Strategies for Neurological Disorders by Mi Eun Kim, Jun Sik Lee

“…This review explores the cellular and molecular mechanisms underlying neuroinflammation, focusing on the roles of microglia, astrocytes, and peripheral immune cells. Key signaling pathways, including NF-κB, JAK-STAT, and the NLRP3 inflammasome, are discussed alongside emerging regulators such as non-coding RNAs, epigenetic modifications, and the gut–brain axis. …”
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Role of CD4+ T and CD8+ T Lymphocytes-Mediated Cellular Immunity in Pathogenesis of Chronic Obstructive Pulmonary Disease by Weilin Xue, Jianying Ma, Yue Li, Chunxia Xie

“…This work was to explore the changes of T lymphocyte subsets in peripheral blood of patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) (AECOPD) and the role of cellular immunity mediated in the disease process. …”
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To Study the Outcome of Low-Cost Negative-Pressure Wound Therapy Using Wall-Mounted Vacuum Device in the Treatment of Open Wounds by Neeraj Jain, Ravi Kant Jain, Ajay Sabhnani

“…It can be done even in peripheral hospitals with low resources. The rate of granulation tissue formation is good with vacuum assisted closure. …”
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A comprehensive review on early detection of drusen patterns in age-related macular degeneration using deep learning models by Kiruthika M, Malathi G

“…As the disease progresses, more and larger deposits develop, and blood vessels grow up from beneath the retina leading to leakage of blood, that damages the retina. In advanced AMD, peripheral vision may remain, but the straight vision is lost. …”
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Ocular and Systemic Risk Factors of Different Morphologies of Scotoma in Patients with Normal-Tension Glaucoma by Ewa Kosior-Jarecka, Dominika Wróbel-Dudzińska, Urszula Łukasik, Tomasz Żarnowski

“…The results of the visual field were allocated as paracentral scotomas, arcuate scotomas, peripheral defects, or hemispheric defects. Statistical analysis was conducted with Statistica 12, and p<0.05 was considered statistically significant. …”
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Transient, Recurrent Central Nervous System Clinical Manifestations of X-Linked Charcot-Marie-Tooth Disease Presenting with Very Long Latency Periods between Episodes: Is Prolonged... by Andria Tziakouri, Konstantinos Natsiopoulos, Kleopas A. Kleopa, Costas Michaelides

“…Charcot-Marie-Tooth disease is one of the most common inherited neurological disorders affecting the peripheral nervous system. The common clinical manifestations of the disease are distal muscle weakness and atrophy, often associated with a characteristic steppage gait and foot deformities. …”
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Hepatitis C Virus Infection and Mixed Cryoglobulinemia by Gianfranco Lauletta, Sabino Russi, Vincenza Conteduca, Loredana Sansonno

“…Among them, complement factors play a crucial role in the cold-insoluble ICs-mediated vasculitis, involving primarily small blood vessels in different tissues including skin, kidney, peripheral, and central nervous system. Liver represents the major target of HCV infection with inflammatory infiltrates, resembling secondary lymphoid follicles. …”
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Unnoticed Women Architects in the Spanish (South)Eastern Mediterranean Region by Ana Gilsanz-Díaz, Manuel Blanco Lage

“…This paper reveals the first results of the study carried out within the framework of the research project «A Situated View: Women’s Architecture in Spain from Peripheral Approaches, 1978-2008», in the context of the regions of Valencia and Murcia in Eastern and Southeastern Spain. …”
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The Role of the Enterohepatic Circulation of Bile Salts and Nuclear Hormone Receptors in the Regulation of Cholesterol Homeostasis: Bile Salts as Ligands for Nuclear Hormone Recept... by Richard N Redinger

“…It is the coordinated transcription factor action of LXR, which responds to ligand binding of circulating oxysterols in both liver and peripheral tissues, and FXR responding to bile salts within the enterohepatic circulation that make possible the regulation of cholesterol and bile acid homeostasis.…”
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ATLAS-seq: a microfluidic single-cell TCR screen for antigen-reactive TCRs by Siwei Luo, Amber Notaro, Lan Lin

“…We use ATLAS-seq to screen TCRs reactive to cytomegalovirus (CMV) or prostate specific antigen (PSA) from peripheral blood mononuclear cells (PBMCs). ATLAS-seq identifies distinct TCR clonotype populations with higher T cell activation levels compared to TCRs recovered by MHC multimer staining. …”
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Simultaneous Left Ventricular and Deep Vein Thrombi Caused by Protein C Deficiency by Harufumi Maki, Motohiro Nishiyama, Motoaki Shirakawa

“…Contrast-enhanced computed tomography revealed a low-density mass in the left ventricle (LV), splenic infarction, and peripheral arterial obstructions in her right leg. Thrombosis extending from the renal vein to the inferior vena cava was also detected. …”
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Do cytokines play a role in the transition from acute to chronic musculoskeletal pain? by Andrea Ebersberger, Hans-Georg Schaible

“…In numerous experimental non-human studies, cytokines have been shown to alter neuronal sensitivity in the peripheral and central nociceptive systems. In this review, we addressed the involvement of cytokines in postoperative pain, complex regional pain syndrome, rheumatoid arthritis, osteoarthritis, temporomandibular joint disease, low back pain and fibromyalgia using PubMed searches including meta-analyses of data. …”
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Infiltration of the liver by cells of innate and adaptive immunity and their destruction in development of experimental immune concanavalin-A-induced hepatitis by S. I. Pavlovich, T. M. Bryzgina, N. V. Makogon, L. I. Aleksyuk, T. V. Martynova, R. I. Yanchy, I. N. Alekseyeva

“…Obtained data assume, that infiltration of the liver by leukocytes, in particular neutrophiles, in combination to ascending necrotic destruction of peripheral cells of innate and adaptive immunity can be the essential pathogenic mechanism at inflammatory liver diseases of T-cell origin.…”
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Perinatal Management for a Pregnant Woman with an MYH9 Disorder by Yuka Yamashita, Rei Matsuura, Shinji Kunishima, Yoshie Oikawa, Hirotsugu Ariizumi, Shoko Hamada, Nahoko Shirato, Ryu Matsuoka, Kohichi Ogawa, Akihiko Sekizawa

“…We diagnosed a primipara woman with an MYH9 disorder during her pregnancy. A peripheral blood smear with an immunofluorescence analysis is the established method of diagnosing MYH9 disorders. …”
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Electromagnetic Fields for the Regulation of Neural Stem Cells by Mengchu Cui, Hongfei Ge, Hengli Zhao, Yongjie Zou, Yujie Chen, Hua Feng

“…Localized magnetic fields (MFs) could easily penetrate the scalp, skull, and meninges, thus inducing an electrical current in both the central and peripheral nervous systems, which is primarily used in transcranial magnetic stimulation (TMS) for inducing specific effects on different regions or cells that play roles in various brain activities. …”
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Age-Related Changes in Trabecular and Cortical Bone Microstructure by Huayue Chen, Xiangrong Zhou, Hiroshi Fujita, Minoru Onozuka, Kin-Ya Kubo

“…With the development of noninvasive imaging techniques such as computed tomography (CT), micro-CT, and high resolution peripheral quantitative CT (HR-pQCT), imaging of the bone architecture provides important information about age-related changes in bone microstructure and estimates of bone strength. …”
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Non-penetrating Deep Sclerectomy and Phacoemulsification Performed in Two Stages in Patients with Glaucoma and Cataract by Francisco Rey García González, Dayamí Pérez Gómez, Rodolfo López Rodríguez., Patricia González Vargas

“…<br /><strong>Methods:</strong> a prospective descriptive study was conducted in 200 patients who underwent non -penetrating deep sclerectomy with mitomycin C and Nd:YAG laser peripheral iridotomy in the first stage and phacoemulsification with intraocular PMMA lens implantation in the second stage. …”
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Long-term results of invasive and non-invasive treatment strategies in the elderly patients with acute coronary syndrome by R.R. Komorovsky

“…According to Cox proportional hazard analysis, low ejection fraction (< 40 %) and concomitant peripheral arterial disease were found to be independent predictors of hard events. …”
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Apremilast generic for the treatment of active psoriatic arthritis: A single-center real-life experience from India by Sanjiv Amin, Aneesa Kapadia, Dhiraj Dhoot, Hanmant Barkate

“…Of these 44 patients, 39 were of peripheral arthritis and five were of axial spondyloarthritis. …”
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Retroperitoneal Cecal Perforation Resulting from Obstructive Ascending Colon Adenocarcinoma by Daniel Paramythiotis, Anestis Karakatsanis, Moysis Moysidis, Diamantoula Pagkou, Petros Bangeas, Antonios Michalopoulos

“…Intestinal perforation may be found on either the site of the tumor or on a more proximal site, caused by distention of the bowel due to peripheral obstruction. This is a case of a 75-year-old female patient who presents in the emergency department with retroperitoneal cecal perforation due to an obstructing tumor of the ascending colon. …”
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