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63101
Assessment of Learning Styles of First-year Medical Students’ using VARK 8.02 Model Questionnaire: A Cross-sectional Study
Published 2025-01-01“…To compare the learning styles of male and female students, Chi-square tests and paired sample t-tests were performed. Results: A total of 125 students participated in the present study. …”
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63102
Integrative bioinformatic approach reveals novel melatonin-related biomarkers for Alzheimer’s disease
Published 2025-02-01“…After intersecting two sets of DEGs and MRGs, we performed Mendelian randomization analysis to identify the MRGs causally related to AD. …”
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63103
Inhibition of the mTOR Pathway Exerts Cardioprotective Effects Partly through Autophagy in CLP Rats
Published 2018-01-01“…Cecal ligation and puncture (CLP) or sham operation (SHAM) was performed in rats. After treatment, pathological changes were determined by H&E staining, cardiac functions by echocardiography, the distribution of microtubule-associated protein light chain 3 (LC-3) type II and hypoxia-inducible factor 1α (HIF-1a) by immunohistochemical staining, and autophagic vacuoles by transmission electron microscopy. …”
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63104
A Muscle Physiology-Based Framework for Quantifying Training Load in Resistance Exercises
Published 2025-01-01“…Methods: Following individual torque–velocity profiling, fifteen participants (11 healthy males, stature: 178.36 ± 3.95 cm, and body mass (BM): 77.48 ± 7.74 kg; 4 healthy females, stature: 169.25 ± 5.03 cm, and body mass: 60.62 ± 3.91 kg) performed isokinetic leg extension exercise sessions at low, moderate, and high intensities (LI, MI, and HI, respectively). …”
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63105
Exploring the anticancer potential of extracts and compounds from the heartwood of Cotinus coggygria Scop. wild growing in Serbia
Published 2025-02-01“…Structure elucidation was performed using NMR spectroscopy. Cytotoxicity was evaluated using MTT assay. …”
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63106
Extracellular matrix turnover in severe COVID-19 is reduced by corticosteroids
Published 2025-01-01“…Longitudinal analysis of ECM neo-epitope changes during ICU stay and their association with mortality was performed, along with an evaluation of the impact of DEX treatment on these markers. …”
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63107
Structural, magnetic, and optical characteristics of undoped and chromium, iron, cobalt, copper, and zinc doped nickel oxide nanopowders
Published 2025-01-01“…Additionally, numerical calculations utilizing the Kramers–Kronig relation were performed to assess the extinction coefficient (k) and refractive index (n) parameters from the reflectance data. …”
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63108
Therapeutic efficacy and mechanism of artesunate for mouse model of polycystic ovary syndrome
Published 2025-02-01“…The estrous cycle was observed, and HE staining was performed for pathological changes in the ovary and uterus. …”
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63109
Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-κB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
Published 2021-01-01“…We conducted quantitative RT-PCR (qRT-PCR) to determine the most effective anti-inflammatory doses without cytotoxicity. We performed ELISA and qRT-PCR for inflammatory cytokines and chemokines and flow cytometry for CD80, the M1 macrophage surface marker, to evaluate the anti-inflammatory effects of empagliflozin and gemigliptin. …”
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63110
Perfusion index as a predictor of successful PNS-guided supraclavicular block: A prospective study
Published 2024-11-01“…This study aims to evaluate the efficacy of PI and the PI ratio as reliable indicators of successful supraclavicular brachial plexus blocks, performed under the guidance of a peripheral nerve stimulator (PNS). …”
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63111
Redox-Modulating Capacity and Effect of Ethyl Acetate Roots and Aerial Parts Extracts from <i>Geum urbanum</i> L. on the Phenotype Inhibition of the <i>Pseudomonas aeruginosa</i> L...
Published 2025-01-01“…This study aimed to investigate the redox-modulating capacity and effect of ethyl acetate (EtOAc) extracts from roots (EtOAcR) and aerial parts (EtOAcAP) of the Bulgarian plant on the phenotype inhibition of the <i>P. aeruginosa</i> Las/RhI quorum sensing (QS) system, which primarily determines drug resistance in pathogenic bacteria, including biofilm formation, motility, and pigment production. We performed QS assays to account for the effects of the two EtOAc extracts. …”
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63112
Identifying a Serum Exosomal-Associated lncRNA/circRNA-miRNA-mRNA Network in Coronary Heart Disease
Published 2021-01-01“…Subsequently, a protein-protein interaction (PPI) network was established to screen out on which hub genes enrichment analyses should be performed, and a ceRNA network (lncRNA/circRNA-miRNA-mRNA) was constructed to elucidate ceRNA axes in CHD. …”
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63113
miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosis
Published 2025-01-01“…HiSeq 2000 sequencing performed differential expression analysis of miRNAs. qRT-PCR and Western blots assessed the expression levels of GPX-4, ACSL-4, HO-1, TFR-1 and TFR-2. …”
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63114
Identification of cancer cell-intrinsic biomarkers associated with tumor progression and characterization of SFTA3 as a tumor suppressor in lung adenocarcinomas
Published 2025-01-01“…Furthermore, a series of biological experiments, including cell viability assays, scratch wound healing assays, and colony formation assays, were conducted to demonstrate the tumor-suppressive effects of SFTA3. RNA sequencing was performed to elucidate the molecular mechanisms underlying the role of SFTA3 in lung cancer cells. …”
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63115
The Anthelmintic Activity of <i>Nepeta racemosa</i> Lam. Against Gastrointestinal Nematodes of Sheep: Rosmarinic Acid Quantification and In Silico Tubulin-Binding Studies
Published 2025-01-01“…MeOH extract, <i>n</i>-hexane, dichloromethane (DCM), ethyl acetate (EtOAc), <i>n</i>-buthanol (<i>n</i>-BuOH) and aqueous (H<sub>2</sub>O) subextracts, and quantify rosmarinic acid in the active extract by the HPLC method, and perform in silico molecular docking studies of rosmarinic acid to examine its binding interactions with tubulin. …”
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63116
Thyroid cancer survival and prognostic factors in Yantai, China (2012–2022): a population-based study
Published 2024-12-01“…Moreover, the Asian population consists of different ethnic groups that are not homogeneous. This study aimed to perform a population-based analysis of survival outcomes and prognostic factors in thyroid cancer patients. …”
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63117
Triglyceride-glucose index: carotid intima-media thickness and cardiovascular risk in a European population
Published 2025-01-01“…Carotid ultrasonography was performed using echographic measurements of the far walls of the left and right common, internal carotids, and bifurcations. …”
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63118
Effects of Walnut Protein Peptides on Promotion of White Adipose Tissue Browning and Prevention of Obesity
Published 2025-02-01“…Body weight, adipose tissue weight and blood lipid levels were monitored, and oral glucose tolerance test (OGTT) was performed. The morphological changes of inguinal WAT were observed, and the protein expression of key factors involved in WAT browning were detected. …”
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63119
HEalth-Related Quality of Life-Intervention in Survivors of Breast and Other Cancers Experiencing Cancer-Related Fatigue and Associated Cognitive Symptoms Using TraditionAL Chinese...
Published 2025-01-01“…Linear regression was performed to evaluate differences between groups at T2 and T3. …”
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63120
Prevalence, management, and outcomes of haemorrhagic events in left ventricular assist device recipients
Published 2022-06-01“…Invasive management was rarely performed. Conclusions Haemorrhagic events in LVAD recipients are frequent and associated with increased mortality. …”
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