A U-shaped non-linear association between serum uric acid levels and the risk of Hashimoto’s thyroiditis: a cross-sectional study by Manli Yan, Wenhua Shi, Ping Gong, Yunsi Xie, Kaiyuan Zhang, Xiang Li, Hua Wei, Hua Wei

“…Therefore, based on the inflection points derived from the RCS analysis, a segmented logistic regression analysis was performed. The findings indicated a significant association between both low and high levels of SUA and HT (Lower OR: 2.043; 95% CI: 1.405-3.019; P < 0.001; Higher OR: 2.369; 95% CI: 0.998-4.999; P = 0.034).ConclusionThis study is the first to reveal a U-shaped association between SUA levels and the risk of HT, suggesting that maintaining SUA levels within the range of 359.0-540.0 μmol/L may help reduce the risk of HT occurrence. …”
Get full text

Prevalence of asymptomatic Leishmania donovani infection and associated factors in Ethiopia: a systematic review and meta-analysis by Habtamu Belay, Adugna Abera, Esayas Aklilu, Tesfahun Bishaw, Ayinalem Alemu, Geremew Tasew, Berhanu Erko

“…Statistical analyses performed using STATA version 16. Publication bias evaluated using funnel plots and Egger’s regression tests. …”
Get full text

Sinking Skin Flap Syndrome following Posttraumatic Hydrocephalus by Ashish Chugh, Prashant Punia, Sarang Gotecha

“…All 212 patients underwent a similar DC following a strict institutional protocol and the craniectomies were performed by the same surgical team. At total of 160 patients survived and elective cranioplasty was planned at a 3-month interval. …”
Get full text

Unveiling the pathways: identifying the multifaceted determinants of low birth weight among neonates in low-income countries: a case-control study by Dube Jara, Angefa Ayele, Dukele Boneya, Jitu Beka, Miesa Gelchu, Alo Edin

“…Data were analysed using Stata V.14, and a multivariable logistic regression model was performed. Statistical significance was declared at a p value<0.05.Results A total of 86 birth records of neonates with low birth weight and 172 birth records of neonates with normal birth weight were reviewed. …”
Get full text

Clinical and radiographic outcomes using standard length of cannulated screws for traditional Latarjet procedure by Juan M. Lopez-Ovenza, MD, Amaury Tapia, MD, Juan I. Duca, MD

“…Functional evaluation was performed with postoperative Rowe and Walch score, visual analog scale for pain and return to sport. …”
Get full text

A novel technique of blindly positioning bronchial blockers for one-lung ventilation: a prospective, randomized, crossover study by Seihee Min, Susie Yoon, Jiwon Han, Jeong-Hwa Seo, Jae-Hyon Bahk

“…During the two-stage maneuver, the same procedure was performed to determine the carinal depth, and the deflated BB was withdrawn and reinserted to a predetermined depth with its tip directed 90 degree toward the target bronchus. …”
Get full text

A new method for detecting mixed Mycobacterium tuberculosis infection and reconstructing constituent strains provides insights into transmission by Benjamin Sobkowiak, Patrick Cudahy, Melanie H. Chitwood, Taane G. Clark, Caroline Colijn, Louis Grandjean, Katharine S. Walter, Valeriu Crudu, Ted Cohen

“…Reconstructed major strain sequences closely matched the true constituent sequence by taking the allele at the highest frequency at hSNPs, while the best-performing approach to reconstruct the minor proportion strain sequence was identifying the closest non-mixed isolate in the same population, though no approach was effective when the minor strain proportion was at 5%. …”
Get full text

Effect of Situational Interactive Respiratory Training System on Patients with Respiratory Dysfunction after Stroke by TAN Lishuang, WANG Na, ZHAO Xiaoxue, DU Tianshu, ZHANG Yan

“…Then, the patient faced the screen and aligns his mouth with the pressure sensor of the training system to perform lip-respiratory breathing. According to the patient's interest, two or three games were selected for respiratory rehabilitation training, one time a day, 15 minutes a time, five days a week, continuous training for eight weeks. …”
Get full text

When can cancer patient treatment nonadherence be considered intentional or unintentional? A scoping review. by Leon Wreyford, Raj Gururajan, Xujuan Zhou

“…<h4>Methods</h4>A Scoping Review was performed to identify peer reviewed studies that concern treatment / medication nonadherence in cancer patients-published between 2000 to 2021 (and partial 2022). …”
Get full text

Is There a Noninvasive Source of MSCs Isolated with GMP Methods with Better Osteogenic Potential? by Carla C. G. Pinheiro, Alessander Leyendecker Junior, Daniela Y. S. Tanikawa, José Ricardo Muniz Ferreira, Reza Jarrahy, Daniela F. Bueno

“…To evaluate whether greater osteogenic potential of the established mesenchymal stem cell strains was associated with an increase in the expression profile of neural crest genes, real-time qPCR was performed on the following genes: SRY-box 9, SRY-box 10, nerve growth factor receptor, transcription factor AP-2 alpha, and paired box 3. …”
Get full text

Genetic divergence of hot pepper lines (Capsicum spp.) in hybrid combinations by Šević Biljana, Cvikić Dejan, Slađana Savić, Tupajić Ivan, Ugirnović Milan, Bajagić Marija, Luković Kristina, Stojiljković Jelena

“…In 2023, a randomized block design experiment with three replications of 40 plants each was conducted in a greenhouse at the Institute for Vegetable Crops Smederevska Palanka. Harvesting was performed at the technological maturity stage. The most important morphological fruit traits and dry matter content (DMC) were analyzed on 10 fruits (kapya type) from each hybrid combination. …”
Get full text

Enhanced antitumor activity of combined hepatic arterial infusion chemotherapy with Lenvatinib and PD-1 inhibitors in unresectable hepatocellular carcinoma: a meta-analysis by Lingling Zhao, Cheng Xu, Jiewen Deng, Yang Ni

“…Subsequently, meta-analyses were performed using RevMan 5.4 to quantitatively evaluate the aggregated effect of the HAIC-L-P regimen versus the L-P regimen alone.ResultsIn our systematic meta-analysis of eight retrospective cohort studies, the HAIC-L-P regimen demonstrated markedly enhanced OS, with an HR of 0.54 (95% CI: 0.45-0.64; p &lt; 0.00001), and enhanced 1-year and 2-year OS rates. …”
Get full text

Glaucoma laser treatments: modern approaches and practice guidelines by M.H. Rabadanova, Zh.G. Oganezova, E.A. Egorov, D.V. Katz, V.V. Novoderezhkin

“…It is underpinned by several important advantages of this modality: it has demonstrated high efficacy; can be performed in outpatient settings without general anesthesia; is well-tolerated by patients; can be repeated over time and combined with surgeries; and is considered as a cost-effective treatment. …”
Get full text

Peculiarities of the clinical picture and diagnosis of dirofilariasis in the maxillofacial area: a series of cases from practice by Kh.A. Buniatian, Yu.V. Khotimska, I.V. Kovach, Yu.Yu. Yaroslavska, O.V. Bondarenko, R.S. Nazaryan

“…All patients were examined by a dentist, and an ultrasound examination of the area with a formation was performed. According to the clinical manifestations, the disease began acutely in nine patients and had a picture of inflamed atheroma (2 – in the zygomatic area, 1 – in the parotid, 2 – in the infraorbital area, 2 – in the temporal area, and 2 – in the area of the nasal bridge). …”
Get full text

Impact of subgingival periodontal treatment on systemic markers of inflammation in patients with metabolic syndrome: a systematic review of randomized clinical trials by Marie Chavez, Asshly Ramirez, Akram Hernández-Vásquez, Daniel Comandé, Diego Azañedo

“…A qualitative synthesis of the evidence was performed.ResultsTwo RCTs with 228 participants (ages 35–65) were included. …”
Get full text

BiomiX, a user-friendly bioinformatic tool for democratized analysis and integration of multiomics data by Cristian Iperi, Álvaro Fernández-Ochoa, Guillermo Barturen, Jacques-Olivier Pers, Nathan Foulquier, Eleonore Bettacchioli, Marta Alarcón-Riquelme, PRECISESADS Flow Cytometry Study Group, PRECISESADS Clinical Consortium, Divi Cornec, Anne Bordron, Christophe Jamin

“…Methylomics analysis is performed using the ChAMP R package. Finally, Multi-Omics Factor Analysis (MOFA) integration identifies shared sources of variation across omics data. …”
Get full text

Effect of Sucrose as Carbon Source and Probiotic Administrations on Bacterial Population Dinamic and Water Quality in White Shrimp, Litopenaeus vannamei Culture by . Sukenda, P. Hadi, E. Harris

“…Attention should be taken to some factors related to deterministic and stochastic factors of aquaculture environment  in order to develop microbe community.  This study was performed to determine effect of sucrose and probiotic supplementation to shrimp culture pond on water quality profile and population dynamic on shrimp culture media.  …”
Get full text

Effect of KRAS mutation status on clinicopathological characteristics and overall survival in patients with rectal cancer by Shengbin Zheng, Zhijie You, Guodon Guo, Zhijing Lin, Siming Wang, Guohua Yang

“…The patients were categorized into two groups according to their KRAS status: wild-type KRAS (wKRAS) and mutant KRAS (mKRAS), with performing research on mKRAS G12D and mKRAS G13D mutation. …”
Get full text

Evaluation of Biologics ACE2/Ang(1–7) Encapsulated in Plant Cells for FDA Approval: Safety and Toxicology Studies by Henry Daniell, Geetanjali Wakade, Smruti K. Nair, Rahul Singh, Steven A. Emanuel, Barry Brock, Kenneth B. Margulies

“…GLP-compliant toxicology studies were conducted on Sprague Dawley rats (<i>n</i> = 120; 15/sex/group) in four groups—placebo, low (1.6/1.0 mg), medium (3.2/2.0 mg), and high (8.3/5.0 mg) doses IP/kg/day. Oral gavage was performed twice daily for 14 days (the dosing phase) followed by the recovery phase (35 days). …”
Get full text

Molecular identification of Leptospira spp. in urine samples from female water buffaloes. Preliminary results by Rosaura Pérez-Gil, Héctor Nava-Trujillo

“…Additionally, Internal 1 and Internal 2 were derived from the sequence of the gene encoding the LipL32 protein and specific to identify pathogenic leptospira, described by Haake et al. (2000). Data analysis was performed with R (Fisher’s exact test). The hematocrit mean was 21%, and all females were negative for hemoparasites (Anaplasma mar ginale, Babesia spp., and Trypanosoma spp.). …”
Get full text