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62841
Effectiveness of eHealth literacy interventions: a systematic review and meta-analysis of experimental studies
Published 2025-01-01“…Methods Following the PRISMA guidelines, we conducted a systematic review in PubMed/Medline, Scopus, Web of Science, Embase, Cochrane Library and ClinicalTrials.gov, including original experimental studies quantifying the effectiveness of interventions aimed at increasing eHL, as assessed by the eHealth Literacy Scale (eHEALS) or other validated scales. We performed a random-effects model meta-analysis comparing changes in eHL levels before and after the interventions, and between the intervention and control groups. …”
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62842
Comprehensive pan-cancer analysis reveals NTN1 as an immune infiltrate risk factor and its potential prognostic value in SKCM
Published 2025-01-01“…We identified genes interacting with and correlated to NTN1 through STRING and GEPIA2, respectively. Subsequently, we performed GO and KEGG enrichment analyses. The results suggested that NTN1 might be involved in crucial biological processes and pathways related to cancer development and progression, including cell adhesion, axon guidance, immune response, and various signaling pathways. …”
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62843
Trends and distribution patterns of infant mortality and maternal HIV positivity in South Africa: A decade review (2007 - 2016)
Published 2024-06-01“…Spearman’s rank-order correlation (rho) was used to correlate infant mortality with data from the 2007 ANCHSS. All analyses were performed with Stata version 16.0. Results. A total sample of 87 805, comprising 43 922 males and 43 883 females, was included in the analysis. …”
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62844
Biological sex, microglial signaling pathways, and radiation exposure shape cortical proteomic profiles and behavior in mice
Published 2025-02-01“…Here, we used a system levels approach to examine how deficiencies in purinergic and fractalkine signaling, two important microglial signaling pathways, impact brain proteomic and behavioral profiles in irradiated and control male and female mice. We performed a comprehensive analysis of the cortical proteomes from irradiated and control C57BL/6J, P2Y12−/−, and CX3CR1−/− mice of both sexes using multiple bioinformatics methods. …”
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62845
Altered functional brain connectivity in Dyt1 knock-in mouse models
Published 2025-02-01“…To accomplish this, we generated two distinct Dyt1 mouse models, one with Dyt1 dGAG knock-in throughout the body (dGAG) and another with a cerebral cortex-specific Dyt1 dGAG knock-in using Emx1 promoter (EMX). In both models, we performed in vivo neuroimaging at ultra-high field (11.1T). …”
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62846
Clinical analysis and case series report on autoimmune glial fibrillary acidic protein astrocytopathy presenting with autonomic dysfunction
Published 2025-01-01“…These findings aim to establish a foundation for personalized diagnosis and treatment strategies in such patients.MethodWe performed a retrospective data analysis from three cases of GFAP-A involvement in autonomic nerves from the Ninth People’s Hospital of Suzhou and the Second Affiliated Hospital of Soochow University from 2020 to 2023. …”
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62847
Risk factors and prognosis analysis of dysphagia after occipitocervical fusion surgery: a retrospective study of 43 cases
Published 2025-01-01“…Pearson or Spearman correlation analysis was performed to assess associations between dnPAS% and each parameter and inter-parameter correlations. …”
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62848
Evaluation of the efficacy of bromfenac sodium in the treatment of dry eye disease
Published 2024-03-01“…Subjective and objective assessment of symptom severity was performed and DED stage was determined before and 4 weeks after treatment with bromfenac sodium 0.09% ophthalmic solution based on the results of the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer's test and Norn's test. …”
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62849
Blockades of effector T cell senescence and exhaustion synergistically enhance antitumor immunity and immunotherapy
Published 2022-10-01“…In addition, melanoma mouse tumor immunotherapy models were performed to explore the synergistical efficacy of antitumor immunity via prevention of tumor-specific T cell senescence combined with anti-programmed death-ligand 1 (anti-PD-L1) checkpoint blockade therapy.Results We report that both mouse malignant tumor cells and Treg cells can induce responder T cell senescence, similar as shown in human Treg and tumor cells. …”
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62850
The diagnostic value and efficacy evaluation of lung ultrasound score in neonatal respiratory distress syndrome: a prospective observational study
Published 2025-01-01“…Each patient underwent both the 14-zone and 12-zone lung ultrasound methods, as well as a chest x-ray, performed after birth and before initiating drug treatment. …”
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62851
Arctiin Protects Chondrocytes from Interleukin-1β-Induced Inflammation and Apoptosis by RNA Sequence In vivo and In vitro
Published 2024-12-01“…Furthermore, Safranin-O fast green staining and immunohistochemistry staining were performed on slices of the mice knee joint to evaluate the OA Research Society International score, alterations in the cartilage matrix, and levels of apoptosis-related proteins at sites of knee cartilage damage in an arthritis model induced by monosodium iodoacetate (MIA) and physical activity. …”
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62852
Gestational Weight Gain and Small for Gestational Age in Obese Women: A Systematic Review and Meta-Analysis
Published 2023-01-01“…Sensitivity analyses were performed for three groups of obese people (I: BMI 30–34.9 kg/m2, II: BMI 35–39.9 kg/m2, and III: BMI ≥ 40 kg/m2) to examine the association of obesity and SGA. …”
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62853
Genomic analysis of the SMN1 gene region in patients with clinically diagnosed spinal muscular atrophy: a retrospective observational study
Published 2025-02-01“…This study demonstrated the importance of performing full-length sequencing for clinically diagnosed SMA to complement current screening methods. …”
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62854
Transjugular Intrahepatic Portosystemic Shunt Placement for Portal Hypertension: Meta-Analysis of Safety and Efficacy of 8 mm vs. 10 mm Stents
Published 2020-01-01“…Overall evaluation of quality and bias for each study was performed. The outcomes assessed were the prevalence of HE, rebleeding or failure to control refractory ascites, and overall survival. …”
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62855
Associations between Life’s Essential 8 and liver function: a cross-sectional study
Published 2025-01-01“…Subgroup analyses were performed based on sex and age to assess potential interactions.ResultsHigher LE8 scores were significantly associated with improved liver function, particularly highlighted by two major findings. …”
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62856
Characterizing immune biomarkers and effector CD8+ T-cell exhaustion in pancreatic adenocarcinoma via single-cell RNA sequencing profiling
Published 2025-01-01“…We analyzed mutations in the shortlisted biomarkers from The Cancer Genome Atlas (TCGA) and performed in silico mutational analysis using Maestro to evaluate the impact of an IL7R mutation (K110N) on protein function. …”
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62857
Resilience Informatics in Public Health: Qualitative Analysis of Conference Proceedings
Published 2025-01-01“…A detailed thematic analysis was performed using an inductive approach, supported by MAXQDA software to manage and organize data. …”
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62858
Impact of bridging with left ventricular assist device on right ventricular function following heart transplantation
Published 2022-06-01“…Transthoracic echocardiography (TTE) was performed in conjunction with right heart catheterization (RHC) at 1, 6, and 12 months after OHT. …”
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62859
Association of childhood maltreatment and adverse lifetime experiences with post-injury psychopathology: evidence from the China Severe Trauma Cohort
Published 2025-01-01“…Mediation analyses were performed to assess the role of adverse lifetime experiences in connecting childhood maltreatment and post-injury psychopathology. …”
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62860
Comparison of Survival Outcomes of Lymphovascular Space Invasion-Negative and Lymphovascular Space Invasion - Positive Women with Stage IIIC Endometrioid Endometrial Cancer: A Case...
Published 2021-04-01“…Study Design: A multicenter, retrospective, department database review was performed to identify lymphovascular space invasion-negative and lymphovascular space invasion-positive stage IIIC endometrioid endometrial cancer at five gynecological oncology centers in Turkey. …”
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