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62621
Relevance of superoxide dismutase type 1 to lipoid pneumonia: the first retrospective case-control study
Published 2025-01-01“…Receiver operating characteristic curve, machine learning (ML), regression and survival analyses were performed to analyze the data. Results In multivariate regression analysis, the sole independent risk factor of LP was the level of SOD1 (OR 0.922, 95% CI: 0.878 ~ 0.967, P < 0.001), while smoking status (β= -0.177, 95% CI -18.645~-2.836, P = 0.008), diabetes mellitus (β= -0.191, 95% CI: -20.442~-3.592, P = 0.005), and total sialic acid (TSA) (β= -0.426, 95% CI: -0.915~ -0.433, P < 0.001) independently influenced the level of SOD1. …”
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62622
Synergistic effects of allantoin and Achyranthes japonica-biochar profoundly alleviate lead toxicity during barley growth
Published 2025-01-01“…The present research introduces a novel use of biochar obtained from the weed Achyranthes japonica to enhance the growth of plants in Pb-contaminated soil. An experiment was performed with 7 treatments: Control, Pb2+ (10 mg kg−1) only, biochar (4 %) only, allantoin (4 g kg−1) only, biochar combined with Pb2+, allantoin combined with biochar, as well as a combination of allantoin and biochar with Pb2+. …”
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62623
Deep-learning-based canopy height model generation from sub-meter resolution panchromatic satellite imagery
Published 2025-01-01“…We show that phenology and species composition play important roles in model transferability; when trained using imagery from a single conifer forest in autumn, the model performs well on autumn imagery from a second conifer forest several hundred kilometers distant with no re-training. …”
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62624
Aqueous extracts of Moringa oleifera and Cinnamomum cassia as promising sources of antibiofilm compounds against mucoid and small colony variants of Pseudomonas aeruginosa and Stap...
Published 2025-06-01“…Solid-liquid extractions were performed on seven biomasses using water and ethanol (70 and 96 %) under controlled conditions, resulting in 21 distinct plant extracts. …”
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62625
Plasma prolactin axis shift from placental to pituitary origin in late prepartum mice
Published 2024-07-01“…To investigate this hypothesis and to seek proteomic changes, we performed a shotgun proteome analysis of the placental tissue using data-independent acquisition mass spectrometry (DIA-MS). …”
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62626
Hospital Prevalence of Colorectal Cancer among Colonoscopy Recipients Attending a Tertiary Hospital in Oman: A Cross-Sectional Study
Published 2020-01-01“…This hospital-based cross-sectional study reviewed reports of colonoscopies performed over 5-years of retrospective follow-up at a tertiary hospital in Oman. …”
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62627
Measurement of CP violation in B0 → D+D − and B s 0 $$ {\textrm{B}}_{\textrm{s}}^0 $$ → D s + D s − $$ {\textrm{D}}_{\textrm{s}}^{+}{\textrm{D}}_{\textrm{s}}^{-} $$ decays
Published 2025-01-01“…Abstract A time-dependent, flavour-tagged measurement of CP violation is performed with B 0 → D + D − and B s 0 $$ {B}_s^0 $$ → D s + D s − $$ {D}_s^{+}{D}_s^{-} $$ decays, using data collected by the LHCb detector in proton-proton collisions at a centre-of-mass energy of 13 TeV corresponding to an integrated luminosity of 6 fb −1. …”
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62628
Analysis of mutations in CDC27, CTBP2, HYDIN and KMT5A genes in carotid paragangliomas
Published 2018-09-01“…The study of molecular pathogenesis of CPGLs will allow developing novel therapeutic approaches and revealing biomarkers. Previously, we performed the exome sequencing of 52 CPGLs and estimated mutational load (ML). …”
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62629
SLC1A5 is a key regulator of glutamine metabolism and a prognostic marker for aggressive luminal breast cancer
Published 2025-01-01“…Statistical analysis was performed using chi-squared tests, ANOVA, Spearman’s correlation, Kaplan–Meier analysis, and Cox regression. …”
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62630
Impact of a nurse-led teleconsultation strategy for cardiovascular disease management during COVID-19 pandemic in India: a pyramid model feasibility study
Published 2022-07-01“…Descriptive analysis was performed to report the proportion of patients triaged by the two-stage telemedicine strategy, and patient’s clinical characteristics, and treatment satisfaction between the nurse-led versus physician-led teleconsultations.Results Overall, nurse-led stage 1 teleconsultations were provided to 12 042 patients with CVD. …”
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62631
Prognostic Accuracy of the Quick Sequential Organ Failure Assessment for Outcomes Among Patients with Trauma in the Emergency Department: A Comparison with the Modified Early Warni...
Published 2021-03-01“…We calculated the qSOFA, the Modified Early Warning Score (mEWS), Revised Trauma Score (RTS), and Injury Severity Score (ISS) based on patients’ initial vital signs and assessments performed in the emergency department (ED). The primary outcome was mortality within 14 days of trauma. …”
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62632
Percutaneous ultrasound-guided radiofrequency ablation for patients with liver metastases from gastrointestinal stromal tumors
Published 2024-12-01“…Multivariate analyses were performed using a Cox proportional hazards model.Results For 79 lesions among 34 patients, all targeted lesions were completely ablated. …”
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62633
Effectiveness of lateral femoral cutaneous and femoral nerve block in managing postoperative pain for hemiarthroplasty patients
Published 2025-02-01“…When patients reported VAS score 3 or 4, the FIC and LFCN plus FN blocks were performed according to group allocation. VAS scores were reassessed 20 minutes after the blocks and recorded. …”
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62634
Identifying strokes in Nigerian children with sickle cell disease as part of clinical trials: training curriculum for healthcare professionals in low-income settings
Published 2025-01-01“…Non-neurologist physicians were trained in-person and via video lectures regarding stroke recognition, performing neurological examinations using the adapted Pediatric NIH Stroke Scale, and acute stroke care. …”
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62635
Investigating shared risk variants and genetic etiology between Alzheimer’s disease and three stress-related psychiatric disorders: a large-scale genome-wide cross-trait analysis
Published 2025-02-01“…Genome-wide cross-trait analysis with association analysis based on subsets and cross-phenotype association were performed to discover genome-wide significant risk variants shared between AD and the three stress-related psychiatric disorders.ResultsA significant positive genetic correlation was observed between AD and major depressive disorder using linkage disequilibrium score regression (rg = 0.231; P = 0.018), genetic covariance analysis (rg = 0.138; P < 0.001), and high-definition likelihood (rg = 0.188; P < 0.001). …”
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62636
Identification of promising SARS-CoV-2 main protease inhibitor through molecular docking, dynamics simulation, and ADMET analysis
Published 2025-01-01“…A comprehensive analysis of compounds from the ChemDiv and PubChem databases was performed. The physicochemical properties, pharmacokinetics, and ADMET (Absorption, Distribution, Metabolism, Excretion, and Toxicity) profiles were evaluated to determine drug similarity and safety. …”
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62637
Deciphering the role of metal ion transport-related genes in T2D pathogenesis and immune cell infiltration via scRNA-seq and machine learning
Published 2025-01-01“…Correlations between immune cells and key RMITRGs were investigated, and the interactions among these genes were explored through protein-protein interaction (PPI) network analysis. Additionally, we performed a detailed cell-cell communication analysis to identify significant signaling pathways in T2D.ResultsOur analysis identified 1953 DEGs between T2D and ND patients, with the Stepglm[backward] plus GBM model demonstrating high predictive accuracy and identifying 13 hub RMITRGs. …”
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62638
Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels
Published 2025-01-01“…Then, at the population level, we performed T-cell repertoire sequencing on 1,815 samples (from 1,521 COVID-19 subjects) as well as 3,500 controls to identify shared “public” T-cell receptors (TCRs) associated with SARS-CoV-2 infection from both CD8 and CD4 T cells.ResultsCollectively, our data reveal that CD8 T-cell responses are often driven by a few immunodominant, HLA-restricted epitopes. …”
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62639
Gait spatiotemporal alterations in schoolchildren with overweight or obesity: a cross-sectional study
Published 2025-01-01“…Methods We carried out a cross-sectional study of 94 schoolchildren aged 6 to 12 years and divided them into three study groups (normal weight, overweight, and obesity). Subsequently, we performed a gait study using a 3D motion analysis system and extracted the spatiotemporal parameters, and we compared the parameters obtained between the study groups. …”
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62640
Endoscopic retrograde cholangiopancreatography combined with extracorporeal shock wave lithotripsy for the removal of large gallbladder stones: a pilot study
Published 2025-01-01“…A paired t test was performed to compare the differences in the main serological indicators before and after EGPC. …”
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