Parsimonious versus extensive bleeding score: can we simplify risk stratification after percutaneous coronary intervention and reduce bleeding events by de-escalation of the antipl... by Pascal Vranckx, Stephan Windecker, Marco Valgimigli, Neil O’Leary, Yoshinobu Onuma, Peter Damman, Eva Christine Ida Woelders, Kai Ninomiya, Denise Adriana Maria Peeters, Arnoud Willem Johannes van 't Hof, Patrick Washington J C Serruys, Robert-Jan Matthijs van Geuns

“…We aimed to compare the predictive and prognostic value of the ‘Zuidoost Nederland Hart Registratie’ (ZON-HR) classification for bleeding risk with the PREdicting bleeding Complications In patients undergoing Stent implantation and subsEquent DAPT (PRECISE-DAPT) score and to determine the effect of ticagrelor monotherapy versus DAPT in patients with or without high bleeding risk (HBR).Methods A post hoc analysis of the GLOBAL LEADERS trial was performed to compare the predictive value of the ZON-HR classification with the PRECISE-DAPT score. …”
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Evaluation of double-balloon enteroscopy in the management of type 1 small bowel vascular lesions (angioectasia): a retrospective cohort study by Suleyman Dolu, Mehmet Emin Arayici, Soner Onem, Ilker Buyuktorun, Huseyin Dongelli, Goksel Bengi, Mesut Akarsu

“…To further investigate the clinical outcomes, the angioectasia group that required endoscopic treatment was divided into two subgroups based on the number of double-balloon enteroscopy (DBE) procedures performed. Univariate and multivariate binary logistic regression analyses were used to establish which predictor variables were significantly related to the recurrence. …”
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«No-reflow» phenomenon and risk factors associated with its development after primary percutaneous coronary interventions in patients with ST elevation myocardial infarction by V.І. Tseluyko, M.M. Doloh, O.A. Leonenko

“…The age of the patients was 36 to 85 years, mean age 60.4 ± 2.03 years. PCI was performed immediately after the diagnosis of STEMI, an average 7.6 ± 1.2 hours after onset of the first symptoms. …”
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Tanshinone I Ameliorates Psoriasis-Like Dermatitis by Suppressing Inflammation and Regulating Keratinocyte Differentiation by Wang Q, Luo X, Su Y, Jin Y, Kuang Q, Li S, Shen W, Zhu Y

“…RNA sequencing (RNA-seq) was performed to investigate Tan-I’s mechanisms in vivo and in vitro, while keratin expression was analyzed by immunofluorescence and Western blot.Results: Tan-I treatment significantly alleviated psoriasis-like lesions in the IMQ mouse model, improving skin pathology and reducing Ki67-positive cells. …”
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Elastosonographic Evaluation of Endometrium in Postmenopausal Bleeding by İsmail Burak Gültekin, Orhan Altınboğa, Serap Gültekin, Elif Akkaş Yılmaz, Gökşen İnanç İmamoğlu, Afra Alkan, Tuncay Küçüközkan

“…B-mode scanning, Doppler and real-time tissue elastography (RTE) were performed by the same single operator, blinded to the study design. …”
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Identification of Breast Cancer Biomarkers by Constructing Protein-Protein Interaction and miRNAs-mRNAs Networks by Azizeh Asadzadeh, Bita Behboodian, Parsa Bernoos, Masoumeh Shojaei Barjouei

“…Gene Ontology and KEGG Pathway Enrichment Analysis were performed by EnrichR. STRING v9. 1 and cytoHubba plugin in Cytoscape (v3.9.1) were used to investigate PPI network construction and identification of hub genes. …”
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Association between Metformin and a Lower Risk of Age-Related Macular Degeneration in Patients with Type 2 Diabetes by Yu-Yen Chen, Ying-Cheng Shen, Yun-Ju Lai, Chun-Yuan Wang, Keng-Hung Lin, Shih-Chao Feng, Chiao-Ying Liang, Li-Chen Wei, Pesus Chou

“…Furthermore, propensity score (PS) matching method was used to choose the matched sample, and PS-adjusted Cox regression was performed. Finally, how HRs changed according to metformin treatment duration and dose was also evaluated in the metformin group. …”
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Identification of CD8+ T Cell-Related Genes: Correlations with Immune Phenotypes and Outcomes of Liver Cancer by Qi Pan, Ying Cheng, Donghua Cheng

“…We used the gene expression matrix of liver cancer and the relative proportion of CD8+ T lymphocytes as input files and performed WGCNA based on this analysis. The weighted coexpression network identified the most CD8+ T lymphocyte-related coexpression modules in liver cancer. …”
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Detention of a person under suspicion of committing a criminal offence and the possibility to appeal in criminal proceedings by V. M. Fedchenko

“…It is emphasized that in addition to the inquirer, investigator, prosecutor, bodies authorized to carry out a pre-trial investigation, subjects who also have the right to detain a person under suspicion of having committed a criminal offense include all policemen, all military personnel serving in the National Guard of Ukraine, all employees of the special law enforcement military formation of the law enforcement service, employees of the State Security Department, military personnel performing duties for the protection of the state border, employees of the special law enforcement body of the Security Service of Ukraine, employees of the state law enforcement agency (NABU), employees of the customs service, officials involved in the anti-terrorist operation, officials and officials of enforcement agencies prisons and detention centers, captains of sea or river vessels of Ukraine located outside its borders, employees of the Department of Economic Security. …”
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Postoperative blood glucose increase can predict all-cause mortality within 3 months after successful interventional recanalization in patients with acute large vessel occlusion ce... by Wensheng Zhang, Yajie Liu, Hongxing Zhou, Jie Li, Weifang Xing, Kaifeng Li, Yudi Li, Xiongjun He, Li Ling, Jinzhao He

“…A multivariable Cox regression was performed to determine independent factors of all-cause mortality after successfully interventional recanalization. …”
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Psychological and autonomous nervous system features of functional gastric dyspepsia and irritable bowel syndrome, duloxetine treatment efficacy by A. P. Pogromov, G. M. Dyukova, M. L. Leonova

“…Psychometric testing was performed: for depression level (Beck Depression Inventory), degree of alexithymia (TAS), anxiety level (Spielberger's State/Trait Anxiety Inventory). …”
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Home-based strength and balance exercises for fall prevention among older individuals of advanced age: a randomized controlled single-blind study by Jian Zhou, Bo Liu, Jian-fang Xu, Fu-bai-hui Wang, Hui Ye, Jin-Ping Duan, Xin-wen Cui

“…The test group (n=63) performed strength and balance exercises facilitated by sports video training (≥ 3 sessions a week, ≥ 30 minutes per session), while the control group (n=61) maintained their daily routines. …”
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Predictors of direct oral anticoagulant concentrations in the trauma population by Laura Adams, Alan M Smith, Louis Perkins, Dmitri Lerner, Jarrett Santorelli, Leslie Kobayashi

“…We sought to identify the prevalence and predictors of subtherapeutic and therapeutic DOAC concentrations and hypothesized that increased anti-Xa levels would correlate with increased risk of bleeding and other poor outcomes.Methods A retrospective cohort study of all trauma patients on apixaban or rivaroxaban admitted to a level 1 trauma center between January 2015 and July 2021 was performed. Patients were excluded if they did not have a DOAC-specific anti-Xa level at presentation. …”
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Crocin Monotherapy in Non-Central Diabetic Macular Edema by Mojtaba Mojtahedzadeh, Masoud Reza Manaviat, Seyed Reza Mirjalili, Adeleh Sahebnasagh, Mohammad Khan Ardani, Farahnaz Hoseinzadeh, Fatemeh Saghafi

“…Methods: This before-after study was performed from October 2019 to August 2021. Twenty-six eyes of 16 patients with type 2 DM in Baghayipoor Clinic in Yazd, were treated with 15 mg crocin per day for 90 days. …”
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The Needs for Visual Improvement of Patients Presented at Low-Vision Center in Wenzhou, China by Xiaoman Li, Guofu Chen, Ruzhi Deng, Na Lin, Lingzhi Ni, Longfei Jiang, Haishuang Lin, Frank Thorn, Jie Chen

“…Women were significantly associated with a concern for performing hobbies (OR 1.45, 95% CI 1.0–2.0) but associated with lower odds of reading (OR 0.46, 95% CI 0.3–0.7). …”
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AMH Is a Good Predictor of Metabolic Risk in Women with PCOS: A Cross-Sectional Study by Miaoxian Ou, Pei Xu, Han Lin, Kaichi Ma, Mingxing Liu

“…Binary logistic regression was performed to examine the risk factors of HOMA-IR. The values of AMH that best predicted the risk of HOMA-IR were also analyzed by ROC curves. …”
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The effects of mindful self-care on medical resident wellness, depression, and burnout by Wendy M. GUYKER, Evette A. ADDAI, Catherine P. COOK-COTTONE, Susan M. ORRANGE, Sofie SCALETTA

“…Data were analyzed using SPSS, with moderation analyses performed to explore self-care’s role in mitigating depression linked to distress. …”
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Metabolite profiling in assessing ulcerative colitis activity: A systematic review by Danyang Cui, Xu Han, Jiazhu Jin, Yanhong Wang, Zijia Chen, Yang Gong, Miao Jiang

“…Qualitative analysis was performed according to the classification of gas chromatography/mass spectrometry, liquid chromatography/mass spectrometry, or nuclear magnetic resonance. …”
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Patients with chronic heart failure and predominant left atrial versus left ventricular myopathy by Xuanyi Jin, Wan Ting Tay, Dinna Soon, David Sim, Seet Yoong Loh, Sheldon Lee, Fazlur Jaufeerally, Lieng Hsi Ling, A. Mark Richards, Adriaan A. Voors, Carolyn S. P. Lam, Joost P. van Melle

“…Methods From a nationwide, prospective, multi-center, observational HF cohort, transthoracic echocardiographic examination was performed on each patient. LA reservoir strain and LV global longitudinal strain (LVGLS) were measured using dedicated software of the two-dimensional speckle tracking analysis to evaluate LA and LV function and to define the myopathy. …”
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Identification of a distinctive immunogenomic gene signature in stage-matched colorectal cancer by Pankaj Ahluwalia, Ashis K. Mondal, Ashutosh Vashisht, Harmanpreet Singh, Ahmet Alptekin, Kalyani Ballur, Nivin Omar, Meenakshi Ahluwalia, Kimya Jones, Amanda Barrett, Vamsi Kota, Ravindra Kolhe

“…Kaplan–Meier and Log-rank tests were used to perform survival analyses. Several independent datasets were explored to validate the gene signature. …”
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