Administration of Vitamin D Metabolites Affects RNA Expression of Xenobiotic Metabolising Enzymes and Function of ABC Transporters in Rats by Karoline Klumpp, Frauke Lange, Alexandra S. Muscher-Banse, Nadine Schnepel, Kathrin Hansen, Adrian L. Lifschitz, Laura Mate, Mirja R. Wilkens

“…Although most studies performed on rodents and cell cultures report an upregulation of respective enzymes and transporters, data from the literature are inconsistent. …”
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A targeted and synergetic nano-delivery system against Pseudomonas aeruginosa infection for promoting wound healing by Chang Ni, Xisheng Li, Haiye Jiang, Shumin Gui, Heng Yin, Xinmin Nie

“…Flow cytometry, bacterial LIVE/DEAD staining and scanning electron microscopy were performed to assess the in vitro antibacterial and anti-biofilm effects of the nanosystems. …”
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Cloning and Functional Analysis of <i>BraTSD2</i> Associated with Root Swelling in Turnip (<i>Brassica rapa</i> L.) by Wenyue Huang, Shifan Zhang, Fei Li, Hui Zhang, Rifei Sun, Guoliang Li, Shujiang Zhang

“…In this study, we cloned the turnip root swelling-related gene <i>BraTSD2</i> (<i>TUMOROUS SHOOT DEVELOPMENT 2</i>) and performed a preliminary functional analysis. The bioinformatics analysis of <i>BraTSD2</i> indicated that the protein is likely to possess a transmembrane feature. …”
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Interpretable machine learning and radiomics in hip MRI diagnostics: comparing ONFH and OA predictions to experts by Tariq Alkhatatbeh, Ahmad Alkhatatbeh, Qin Guo, Jiechen Chen, Jidong Song, Xingru Qin, Wang Wei

“…Then NaiveBayes (NB) was selected to establish our final Radiomics-model as it performed the best. Three users with different expertise and backgrounds diagnosed and labeled the dataset into either OA or ONFH. …”
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Viral and immune dynamics of genital human papillomavirus infections in young women with high temporal resolution. by Nicolas Tessandier, Baptiste Elie, Vanina Boué, Christian Selinger, Massilva Rahmoun, Claire Bernat, Sophie Grasset, Soraya Groc, Anne-Sophie Bedin, Thomas Beneteau, Marine Bonneau, Christelle Graf, Nathalie Jacobs, Tsukushi Kamiya, Marion Kerioui, Julie Lajoie, Imène Melki, Jean-Luc Prétet, Bastien Reyné, Géraldine Schlecht-Louf, Mircea T Sofonea, Olivier Supplisson, Chris Wymant, Vincent Foulongne, Jérémie Guedj, Christophe Hirtz, Marie-Christine Picot, Jacques Reynes, Vincent Tribout, Édouard Tuaillon, Tim Waterboer, Michel Segondy, Ignacio G Bravo, Nathalie Boulle, Carmen Lía Murall, Samuel Alizon

“…We enrolled 189 women aged from 18 to 25 and living in the area of Montpellier (France) between 2016 and 2020. We performed 974 on-site visits for a total of 1,619 months of follow-up. …”
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ALKBH5 alleviates lower extremity arteriosclerosis by regulating ITGB1 demethylation and influencing macrophage polarization by Zeyu Guan, Xiaogao Wang, Chao Xu, Ran Lu

“…Oil Red O staining and hematoxylin and eosin (HE) staining were performed to measure the area of atherosclerotic plaques and the size of the necrotic core in mouse femoral artery, respectively. …”
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Longitudinal Associations between Obesity, Inflammation, and the Incidence of Type 2 Diabetes Mellitus among US Black and White Adults in the CARDIA Study by Sharon H. Jackson, Anna Bellatorre, Timothy McNeel, Anna María Nápoles, Kelvin Choi

“…Diabetes status was determined in wave 8 based on self-report, blood glucose level, and anti-hyperglycemic medication use in conjunction with a homeostatic model assessment-based classification for distinguishing diabetes subtype. We performed a series of multivariable logistic regression analyses to assess the relative influence of obesity (waist circumference) and individual inflammatory biomarkers (i.e., C-reactive protein, fibrinogen, and sex-specific serum uric acid and gamma-glutamyltransferase) on the odds of developing incident T2DM between waves 7 and 8. …”
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The Prognostic Significance of the CALLY Index in Ampullary Carcinoma: An Inflammation-Nutrition Retrospective Analysis by Xi P, Huang G, Huang K, Qin D, Yao Z, Jiang L, Zhu Q, He C

“…Univariate and multivariate Cox regression analyses, along with competing risk analysis, were performed to identify prognostic factors for AC after pancreaticoduodenectomy (PD). …”
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Noninvasive Evaluation of EGFR Expression of Digestive Tumors Using 99mTc-MAG3-Cet-F(ab′)2-Based SPECT/CT Imaging by Dai Shi, Yiqiu Zhang, Zhan Xu, Zhan Si, Yuan Cheng, Dengfeng Cheng, Guobing Liu

“…Furthermore, 99mTc-MAG3-Cet-F(ab′)2 SPECT/CT was performed on MGC803 and HT29 tumor-bearing nude mice. …”
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The influencing factors of the erythropoietin resistance index and its association with all-cause mortality in maintenance hemodialysis patients by Xinju Zhao, Liangying Gan, Fan Fan Hou, Xinling Liang, Xiaonong Chen, Yuqing Chen, Zhaohui Ni, Li Zuo

“…Stepwise multivariate logistic regression was used to identify the related risk factors, and subgroup analyses were performed. A total of 1270 MHD subjects (687 males and 583 females) were included, with an average age of 60 (49.0, 71.0) years. …”
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Do non-mammary conditions influence patients’ cosmetic perception after breast conserving surgery? by Idam de Oliveira-Junior, Idam de Oliveira-Junior, Fabíola Cristina Brandini da Silva, Fabíola Cristina Brandini da Silva, Almir José Sarri, René Aloísio da Costa Vieira, René Aloísio da Costa Vieira

“…Student’s t test and Mann-Whitney were used to assess the relationship between QOL and cosmetic results. The ANOVA were performed with the adjusted Bonferroni correction to compare the four groups.ResultsA total of 300 patients were evaluated, 298 underwent self-assessment of the breasts (76.8% satisfactory results and 23.2% unsatisfactory) and 297 underwent BCCT.core evaluation (29.9% satisfactory results and 79.1% unsatisfactory), which had a kappa of 0.095 (p = 0.01). …”
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The systemic oxidative stress index predicts clinical outcomes of esophageal squamous cell carcinoma receiving neoadjuvant immunochemotherapy by Jifeng Feng, Jifeng Feng, Liang Wang, Xun Yang, Qixun Chen, Qixun Chen

“…In terms of prognostication, the RPA model performed significantly better than TNM classification.ConclusionSOSI is a simple and useful score based on available SOS-related indices. …”
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A minimally invasive animal model of atherosclerosis and neointimal hyperplasia for translational research by Max L. A. Ebert, Vanessa F. Schmidt, Osman Öcal, Anne von Thaden, Olaf Dietrich, Bastian Popper, Sandra Elges, Max Seidensticker, Jens Ricke, Melanie A. Kimm, Astrid Jeibmann, Moritz Wildgruber

“…Methods Endothelial denudation was performed via a minimally invasive approach through the auricular artery, followed by stent-retriever mediated endothelial injury in New Zealand White rabbits (n = 10). …”
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Effects of Renal Denervation via Renal Artery Adventitial Cryoablation on Atrial Fibrillation and Cardiac Neural Remodeling by Wei Wang, Zhaolei Jiang, Rongxin Lu, Hao Liu, Nan Ma, Jie Cai, Min Tang, Ju Mei

“…After 2 months of postoperative recovery, AF vulnerability, AF duration, and histological examination were performed in both groups. Results. Compared with the Sham group, left stellate ganglion (LSG) tissue fibrosis was increased in the LRDN group. …”
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Using benthos a bioindicator to assess the efficiency constructed wetland community wastewater treatment system by K. Seethong, K. Chunkao, N. Dampin, W. Wararam

“…Statistical tests were performed to analyze the water quality data.FINDINGS: The study observed a decrease in Chironomid abundance in both constructed wetland systems, indicating their effectiveness in treating wastewater. …”
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Multi-ancestry genome-wide association analyses: a comparison of meta- and mega-analyses in the Hyperglycemia and Adverse Pregnancy Outcome (HAPO) study by Alan Kuang, Marie-France Hivert, M. Geoffrey Hayes, William L. Lowe, Denise M. Scholtens

“…Classically, multi-ancestry GWAS analyses are performed using statistical meta-analysis to combine results conducted within homogeneous ancestry groups. …”
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Whole transcriptome analysis and construction of gene regulatory networks of granulosa cells from patients with polycystic ovary syndrome (PCOS) by Yuan Yuan, Daiterigele, Qian Zhang, Chen Du

“…We used the standard long protocol to collect granulosa cells from two groups, who underwent assisted reproduction at the Reproductive Medicine Center of the Affiliated Hospital of Inner Mongolia Medical University, China. We performed whole-transcriptome sequencing using RNA-Seq technology to construct transcriptome patterns of messenger RNAs (mRNAs), long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs). …”
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Relationship of monocyte to high-density lipoprotein ratio (MHR) and other inflammatory biomarkers with sarcopenia: a population-based study by Zhiwei Xue, Jian Cao, Jianhui Mou, Rui Wang, Peng Liu

“…Multiple logistic regression was performed to explore the association between ln-transformed MHR, SII, NLR, NHHR and low muscle mass. …”
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Postoperative mortality in New Zealand following general anaesthetic: demographic patterns and temporal trends by James Stanley, Sarah Jackson, Jason K Gurney, Melissa McLeod, Doug Campbell, Luke Boyle, Elizabeth Dennett, Jonathan Koea, Dick Ongley, Diana Sarfati

“…We also present temporal trends and consider how rates in postoperative death following acute and elective/waiting list procedures have changed over this time period.Results and conclusion A total of 1 836 683 unique patients accounted for 3 117 374 admissions in which a procedure was performed under general anaesthetic over the study period. …”
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Analysis of the characteristics of the ejector mode of the pulse detonation propulsion system of the combined acceleration cycle by Olena Zolotko, Oleksandr Zolotko, Oleksandr Aksonov, Vitalii Stoliarchuk, Oleksandr Cherniavskyi

“…An analysis of the concept of multi-mode engines in transatmospheric aircraft was performed. The most famous of them include: two-mode direct-jet engine (ramjet-scramjet engine); rocket-based combined cycle (RBCC) engine; hybrid air-breathing rocket engine (Synergetic Air-Breathing Rocket Engine, SABRE). …”
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