HGF-Modified Dental Pulp Stem Cells Mitigate the Inflammatory and Fibrotic Responses in Paraquat-Induced Acute Respiratory Distress Syndrome by Panpan Geng, Yuning Zhang, Huan Zhang, Xiwen Dong, Yuefeng Yang, XiaoNa Zhu, Chu-Tse Wu, Hua Wang

“…Extracellular vesicles (EVs) derived from MSCs performed more effectively than MSCs’ supernatant. …”
Get full text

Identification of SETD4 as an Onco‐Immunological Biomarker Encompassing the Tumor Microenvironment, Prognoses, and Therapeutic Responses in Various Human Cancers by Yuyun Zhong, Ruiqi Wang, Zijie Huang, Zhaoting Hu, Bin Peng, Bin Chen, Liyue Sun

“…Additionally, qRT‐PCR was performed to validate SETD4 expression in clinical specimens. …”
Get full text

Comprehensive bioinformatics analysis identifies hub genes associated with immune cell infiltration in early-onset schizophrenia by Shasha Wu, Tailian Xue, Yilin Li, Weikang Chen, Yan Ren

“…Subsequently, a PPI network was constructed to select the top 10 potential hub genes, and functional analysis was performed by GeneMANIA, resulting in the identification of four immune-related genes. …”
Get full text

Infantile epileptic spasms syndrome: an etiologic study of 361 patients with infantile epileptic spasms syndrome by Linghui Zhu, Linghui Zhu, Yuan Xia, Yuan Xia, Hao Ding, Tong Zhang, Jun Li, Baomin Li, Baomin Li

“…Our study intends to summarize the etiology of IESS and analyze its characteristics.MethodsA retrospective analysis was performed to gather clinical data from patients diagnosed with IESS at the Department of Neurology of Qilu Hospital of Shandong University and the Children's Hospital Affiliated to Shandong University between June 2017 to May 2024.ResultsA total of 361 patients with IESS were included, comprising 115 structural cases (31.9%), 37 genetic cases (10.2%), 32 genetic-structural cases (8.9%), 9 metabolic cases (2.5%), 3 infectious cases (0.8%), and 165 cases with unknown etiology (45.7%). …”
Get full text

Comparison of HCG Trigger versus Dual Trigger in Improving Pregnancy Outcomes in Patients with Different Ovarian Responses: A Retrospective Study by Ke Xu, Jinrong Wang, Shuangshuang Yang, Zhenjing Wang, Ning Hou, Mei Sun

“…Subsequently, a detailed statistical analysis was performed on 1032 patients following an antagonist regimen. …”
Get full text

Identification and Analysis of Potential Immune-Related Biomarkers in Endometriosis by Yanan He, Jixin Li, Yanjun Qu, Liyuan Sun, Xibo Zhao, Han Wu, Guangmei Zhang

“…Gene Ontology (GO) and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway enrichment analyses were performed on the DETFs and DEIRGs. Then, DETFs and DEIRGs were further validated in the external datasets of GSE51981 and GSE1230103. …”
Get full text

Novel Algorithm for Surgical Management of Cervical Ossification of Posterior Longitudinal Ligament: A Retrospective Cohort Study With 2‐Year Follow‐Up by Zhuyun Cai, Hui Kang, Lei Quan, Yilong Ren, Meng Fang, Yixuan Tan, Haochen Zhang, Xuhui Zhou, Jun Ma

“…ACAF surgery is an ideal choice for Type I patients, with ossification located between UPs, while for patients with ossification exceeding UPs, it is better to perform anterior cervical corpectomy and fusion or posterior surgery.…”
Get full text

Pharmacodynamic Profiling of Amoxicillin: Targeting Multidrug-Resistant Gram-Positive Pathogens <i>Staphylococcus aureus</i> and <i>Staphylococcus pseudintermedius</i> in Canine Cl... by Syed Al Jawad Sayem, Ga-Yeong Lee, Muhammad Aleem Abbas, Seung-Chun Park, Seung-Jin Lee

“…Additionally, time-kill assays and post-antibiotic effect (PAE) assessments were performed. Epidemiological cutoff (ECOFF) values were established for both species to guide therapy. …”
Get full text

Evaluating the association between lipidome and female reproductive diseases through comprehensive Mendelian randomization analyses by Ye Ma, Fang Wu, Zeming Yu, Lu Yang

“…Subsequently, a range of comprehensive evaluations were performed, including sensitivity analysis, mediation MR analysis, reverse MR analysis, and steiger test. …”
Get full text

Genome-Wide Identification and Expression Analysis of the <i>CAMTA</i> Gene Family in Roses (<i>Rosa chinensis</i> Jacq.) by Wanyi Su, Yuzheng Deng, Xuejuan Pan, Ailing Li, Yongjie Zhu, Jitao Zhang, Siting Lu, Weibiao Liao

“…Calmodulin-binding transcription activator (<i>CAMTA</i>), as one of the transcription factors, is involved in performing important functions in modulating plant stress responses and development in a Ca²⁺/CaM-driven modus. …”
Get full text

Language function improvement and cortical activity alteration using scalp acupuncture coupled with speech-language training in post-stroke aphasia: A randomised controlled study by Bingbing Lin, Jinglei Ni, Xiao Xiong, Lanlan Zhang, Jian Song, Mengxue Wang, Linsong Chai, Yunshi Huang, Jia Huang

“…All assessments were performed at baseline and post-intervention. Results: The acupuncture group showed significant improvements in WAB subscales (Spontaneous Speech, Comprehension, Repetition, Naming, and AQ) with all changes statistically significant (P < 0.001). …”
Get full text

Therapeutic drug monitoring and neutralizing anti-drug antibody detection to optimize TNF-alpha inhibitor treatment for uveitis by Howard C. Chen, Jenny Shunyakova, Amit K. Reddy, Srujay Pandiri, Lynn Hassman

“…Here, we investigated the use of therapeutic drug monitoring and neutralizing anti-drug antibody detection as a strategy to optimize tumor necrosis factor (TNF)-alpha inhibitor treatment in patients who have a suboptimal response to the initial dosing of adalimumab.MethodRetrospective cohort study performed in two tertiary referral uveitis services in the United States between 2015 to 2023. …”
Get full text

Global research trends on gastrointestinal cancer and mental health (2004–2024): a bibliographic study by Wenjin Han, Tianmeng Wang, Zhiqiang He, Caihua Wang, Zhaozhao Hui, Shuangyan Lei, Nan Hao, Ning Li, Xiaoqin Wang, Xiaoqin Wang

“…VOS Viewer was used to identify keyword co-occurrences, while CiteSpace was utilized to generate network visualizations, produce dual-map overlays of journals, and perform burst keyword analysis.ResultsA total of 1,118 publications were included for analysis. …”
Get full text

Oblique Lumbar Interbody Fusion Combined With Anterolateral Fixation and Cement Augmentation for the Treatment of Degenerative Lumbar Diseases in the Elderly Population: A Retrospe... by Weiqi Han, Lei He, Fei Wang, Xiaofeng Zhao, Cong Jin

“…Clinical and radiographic outcomes were compared among the groups, and logistic regression analyses were performed to identify risk factors for cage subsidence after OLIF. …”
Get full text

Use of virtual reality in port implantation to reduce perioperative anxiety and pain: protocol for a randomised controlled pilot trial at a single German university hospital (VIP-t... by Christoph W Michalski, Felix J Hüttner, Colette Dörr-Harim, Sandra Graf, Hannah Feldmann, Lisa S Hunold, Kira C Steinkraus, Nadir Nasir

“…Introduction Intravenous access port implantation is commonly performed under local anaesthesia, which offers advantages such as increased patient satisfaction and resource savings compared with general anaesthesia. …”
Get full text

Gender Preferences in Healthcare: A Study of Saudi Patients&rsquo; Physician Preferences by Alhomayani KM, Bukhary HA, Aljuaid FI, Alotaibi TA, Alqurashi FS, Althobaiti KN, Althobaiti NS, Althomali OY, Althobaiti AA, Aljuaid MM, Muhyei AM

“…Data analysis, including descriptive statistics and subgroup comparisons, was performed using JMP version 14 Pro.Results: The sample showed a predominance of females (62.1%) and younger participants (18– 25 years). …”
Get full text

Survival of Salmonella on Biodegradable Mulch, Landscape Fabric, and Plastic Mulch by Alyssa A. Rosenbaum, Claire M. Murphy, Annette L. Wszelaki, Alexis M. Hamilton, Steven L. Rideout, Laura K. Strawn

“…If counts dropped below the detection limit (<0.12 log CFU/cm2), enrichments were performed following the Food and Drug Administration’s Bacteriological Analytical Manual Salmonella protocol. …”
Get full text

Epidemiology, Disease Severity and Outcome of Severe Acute Respiratory Syndrome Coronavirus 2 and Influenza Viruses Coinfection Seen at Egypt Integrated Acute Respiratory Infection... by Manal Fahim, Wael H. Roshdy, Ola Deghedy, Reham Kamel, Amel Naguib, Shymaa Showky, Nancy Elguindy, Mohammad Abdel Fattah, Salma Afifi, Amira Mohsen, Amr Kandeel, Khaled Abdelghaffar

“…Data from all patients with coinfection were obtained, and descriptive data analysis was performed for patients’ demographics, clinical course, and outcome. …”
Get full text

Multisource Accident Datasets-Driven Deep Learning-Based Traffic Accident Portrait for Accident Reasoning by Chun-Hao Wang, Yue-Tian-Si Ji, Li Ruan, Joshua Luhwago, Yin-Xuan Saw, Sokhey Kim, Tao Ruan, Li-Min Xiao, Rui-Jue Zhou

“…How to use multisource data based on deep learning, especially based on the Chinese recent unstructured data and structured data to establish accident portrait for individual and groups of accident drivers, still lacks. Moreover, how to perform multisource accident data label extraction, identity, and relationship extraction are still challenging problems. …”
Get full text

The prevalence and prognostic significance of Sarcopenia and Adipopenia in Pleural Mesothelioma by Andrew C. Kidd, Gordon W. Cowell, Geoffrey A. Martin, Jenny Ferguson, Dean A. Fennell, Matt Evison, Kevin G. Blyth

“…We determined the prevalence, prognostic significance and clinicopathological correlates of sarcopenia and adipopenia in Pleural Mesothelioma (PM) patients receiving chemotherapy. Methods: We performed a multi-centre retrospective cohort study. …”
Get full text