Saussurea gossypiphora extracts reduce inflammation by reversing inflammatory cytokine levels in in-vitro and in-vivo by Kalyani Jatoth, Pawan Kumar Anoor, Ramesh Kande, Sandeepta Burgula

“…Effect of MESGD on inflammasome pathway was studied by performing ELISA for IL-1β, TNF-α and confirmed by immunoblotting for NLRP3 and Caspase 1 in THP1 cells. …”
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Novel approach for noninvasive pelvic floor muscle strength measurement using extracorporeal surface perineal pressure measurement and machine learning modeling by Ui-jae Hwang, Sun-hee Ahn, Hyeon-ju Lee, Yurin Jeon, Myung Jae Jeon

“…Significant correlations were observed between bladder base displacement and middle ( r  = .619, P  < .001) and front ( r  = −.379, P  =.002) vectors. The top-performing models for predicting bladder base displacement were the support vector machine [root mean square error (RMSE) = 0.139, R2 = 0.542], random forest (RMSE = 0.123, R2 = 0.367), and AdaBoost (RMSE = 0.123, R2 = 0.320) on the training set, and AdaBoost (RMSE = 0.173, R2 = 0.537), random forest (RMSE = 0.177, R2 = 0.512), and support vector machine (RMSE = 0.178, R2 = 0.508) on the test set. …”
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Characteristics, Mortality, and Clinical Outcomes of Hospitalized Patients with COVID-19 and Diabetes: A Reference Single-Center Cohort Study from Poland by Michał Kania, Konrad Mazur, Michał Terlecki, Bartłomiej Matejko, Jerzy Hohendorff, Zlata Chaykivska, Mateusz Fiema, Marianna Kopka, Małgorzata Kostrzycka, Magdalena Wilk, Tomasz Klupa, Przemysław Witek, Barbara Katra, Marek Klocek, Marek Rajzer, Maciej T. Malecki

“…The data analysis of patients admitted between March 6, 2020, and May 31, 2021, to the University Hospital in Krakow (Poland), a reference center for COVID-19, was performed. The data were gathered from their medical records. …”
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Efficacy and Safety of Transcutaneous Electrical Acupoint Stimulation for Postoperative Pain: A Meta-Analysis of Randomized Controlled Trials by Dan Wang, Hongshuo Shi, Zhenguo Yang, Wenbin Liu, Lu Qi, Chengda Dong, Guomin Si, Qi Guo

“…Subgroup analysis was performed according to open surgery and minimally invasive surgery. …”
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Magnitude of fruit and vegetable consumption and its associated factors among patients with type 2 diabetes mellitus (T2DM) attending health services at selected health centers in... by Lelisa Worku, Burtukan Hussien, Teshome Bekele Elema, Taferi Atomsa Rekiti, Amana Ogatu Luke, Addisu Tadesse Sime

“…Descriptive statistics were performed to describe the study population’s characteristics, while logistic regression was used to identify the factors linked to FV consumption.Results The study’s findings indicated that the recommended amount of FV consumption was low among study participants at 25.8%, with a range of 20.9%–31.5%. …”
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Identifikasi Bakteri Coliform pada Kontak Permukaan Galon Air Minum Isi Ulang Distribusi Akhir di Kecamatan Bungus by Herik Okta Jonanda, Aziz Djamal, Yulistini .

“…Cross-sectional study</em><em> was</em><em> performed on 18 samples from 9 depot refill drinking water which is divided into each of 2 gallons per refill drinking water depot. …”
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Effect of Catheterization Time combined with Volume on Patients with Incomplete Bladder Emptying after Stroke by Huiying ZHANG, Xiuqin SHAO, Tianzi ZOU, Xiaoyue LI, Shuang QUAN, Tongzhou MI

“…Bladder volume before urination and residual urine volume after micturition were dynamically monitored by BladderScar (BVI9400) and micturition diary bedside, and intermittent catheterization was performed when the urine volume reached"bladder safety capacity". …”
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The Safety and Efficacy of the Repeated PRRT with [90Y]Y/[177Lu]Lu-DOTATATE in Patients with NET by Anna Zemczak, Paweł Gut, Dariusz Pawlak, Maciej Kołodziej, Leszek Królicki, Beata Kos-Kudła, Marek Ruchała, Grzegorz Kamiński, Jolanta Kunikowska

“…Out of 99 treated patients with G1 and G2 NETs, 26 were included in the study and treated with the repeated PRRT (with 5 undergoing the re-repeated PRRT treatment) after an initial positive response to four PRRT cycles and later progression of the disease. [68Ga]Ga-DOTATATE PET/CT and CT/MRI procedures were performed before and after the treatment. Patients were treated with [90Y]Y/[177Lu]Lu-DOTATATE (1 : 1) with mixed amino acid infusion for kidney protection. …”
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Optic Nerve Head Hemoglobin Levels in Glaucoma: A Structural and Functional Correlation Study by Janaina A. G. Rocha, Diego T. Dias, Maria Betânia C. Lemos, Fábio N. Kanadani, Augusto Paranhos, Carolina P. B. Gracitelli, Tiago S. Prata

“…A secondary analysis was performed to compare each parameter between three different glaucoma groups divided according to VFMD values (mild, >−6 dB; moderate, −6 to −12 dB; and advanced, <−12 dB). …”
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Deciphering salt-responsive NB-ARC genes in rice transcriptomic data: A bioinformatics approach with gene expression validation by Saputro Triono Bagus, Wardhani Fila Oxi, Sholihah Nur Fadlilatus, Ermavitalini Dini, Purnama Putut Rakhmad, Nurhidayati Tutik

“…Determination of functional marker genes is essential to perform a concise and fast method for selection. This research focuses on pinpointing candidate genes suitable for functional markers. …”
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Robotic Assistance in Percutaneous Liver Ablation Therapies: A Systematic Review and Meta-Analysis by Ana K. Uribe Rivera, MD, Barbara Seeliger, MD, PhD, Laurent Goffin, MSc, Alain García-Vázquez, MD, Didier Mutter, MD, PhD, Mariano E. Giménez, MD, PhD

“…A meta-analysis was performed, including comparative studies of freehand and robotic techniques in terms of radiation dose, accuracy, and Euclidean error. …”
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Changes in quality of life 5 years after sleeve gastrectomy: a prospective cohort study by Karl Ove Hufthammer, Tone Merete Norekvål, Grethe S Tell, Ronette L Kolotkin, Tone Nygaard Flølo, Anny Aasprang, Villy Våge, John Roger Andersen

“…Objectives Sleeve gastrectomy (SG) is the most frequently performed bariatric surgery procedure worldwide, but reports on long-term quality of life (QOL) outcomes are scarce. …”
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Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis by Li-wei Huang, Hua-min Li, Bei He, Xiao-bo Wang, Qi-zhi Zhang, Wen-xing Peng

“…Sensitivity and subgroup analysis were performed to assess the robustness of the results and to identify sources of heterogeneity. …”
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Effect of tropical climates on the quality of commonly used antibiotics: the protocol for a systematic review and meta-analysis by Johnstone Thitiri, Moses Ngari, Christina W Obiero, James A Berkley, Tsegaye Melaku, Sultan Suleman, Gemmechu Hasen, Sileshi Belew, Jimmy Shangala

“…Meta-analysis using random effects will be performed using RevMan software to determine the pooled effects of environmental exposures. …”
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Workplace and social support, treatment satisfaction, and their impact on quality of life in Swedish women with multiple sclerosis: a cross-sectional survey study by Emilie Friberg, Katharina Fink, Alejandra Machado, Elin Wredendal

“…Odds of perceived satisfactory support in one, two or all three support dimensions (work, social or treatment) were performed with multinomial logistic regressions.Results Lower MS severity and fatigue, higher cognitive processing speed, living in cities and higher educational attainment were individually associated with higher levels of HRQoL (p&lt;0.001). …”
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The Association between Serum Level of Vitamin D and Inflammatory Biomarkers in Hospitalized Adult Patients: A Cross-Sectional Study Based on Real-World Data by Xiaomin Zhang, Zhiqi Chen, Yi Xiang, Yiquan Zhou, Molian Tang, Jun Cai, Xinyi Xu, Hongyuan Cui, Yi Feng, Renying Xu

“…Materials and Methods. We performed the current study based on real-world data from two teaching hospitals. …”
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Systemic therapy of skin metastatic melanoma with BRAF gene mutation by Yu. S. Shakh-Paronyants, S. V. Cheporov, N. P. Shiryaev, A. V. Ukgarskiy, P. V. Nesterov, N. S. Korzina

“…The patients were divided into two groups: the first group (n = 18) included patients who received mono‑mode immunotherapy in the first line of treatment; the second group (n = 43) included patients who underwent targeted first-line therapy.Standard regimens of monotherapy with BRAF inhibitors (vemurafenib, dabrafenib) or combination therapy with BRAF and MEK inhibitors (dabrafenib + trametinib) were chosen as treatment. Immunotherapy was performed using the following drugs: pembrolizumab, nivolumab and prolgolimab. …”
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Celastrol promotes DNA damage and apoptosis in uterine corpus endometrial carcinoma via promotion of KAT2B-mediated RBPJ acetylation and repression of MCM4 transcription by Lipeng Pei, Yan Zhu, Wenpeng Li, Bin Xu, Jingli Sun

“…Bioinformatic analysis, protein coimmunoprecipitation (Co-IP), luciferase assay, cell experiments were performed to reveal the relationship of Celastrol/KAT2B/RBPJ/MCM4 in UCEC. …”
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Impact of regionalisation and case-volume on neonatal and perinatal mortality: an umbrella review by Jochen Schmitt, Stefanie Deckert, Mario Rüdiger, Felix Walther, Denise Bianca Küster, Anja Bieber, Jürgen Malzahn

“…Objective This umbrella review summarises and critically appraises the evidence on the effects of regulated or high-volume perinatal care on outcome among very low birth weight/very preterm infants born in countries with neonatal mortality &lt;5/1000 births.Intervention/exposition Perinatal regionalisation, centralisation, case-volume.Primary outcomes Death.Secondary outcomes Disability, discomfort, disease, dissatisfaction.Methods On 29 November 2019 a systematic search in MEDLINE and Embase was performed and supplemented by hand search. Relevant systematic reviews (SRs) were critically appraised with A MeaSurement Tool to Assess systematic Reviews 2.Results The literature search revealed 508 hits and three SRs were included. …”
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Cultured sand sea cucumber growth with different water exchange systems by Debora Liubana, Joi Alfreddi Surbakt, Claudya Zyta Tobu

“…This study determined the sea cucumber growth cultured in an integrated multi-trophic aquaculture (IMTA) with different water exchange systems in Lifuleo waters from October to December, 2020. This study was performed in an experimental method with three different exchange system treatments and three replications, namely once every 2 days (tank A), every day (tank B), and water circulation every day (tank C). …”
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