Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway by Hui Huang, Qun Huang, Jing Wang, Wanjie Wang, Yanlin Zheng

“…CCK-8, wound healing, and Transwell assays were performed to detect the viability, migration, and invasion of the cells. …”
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A pan-cancer analysis: predictive role of ZNF32 in cancer prognosis and immunotherapy response by Minghan Li, Chang Su, Qianru Wang, Yuetong Chen, Di Jiang, Weijia Wang, Shunjin Chen, Xiangping Li, Ming Fu, Juan Lu

“…We investigated correlations between ZNF32 expression and various factors such as prognosis, immune infiltration, immunotherapy, DNA methylation, and biological functions. Furthermore, we performed in vitro research to validate the significance of ZNF32 in head and neck cancer (HNSC). …”
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Tinnitus Suppression with Electrical Stimulation at the Most Basal Contact of the Cochlear Implant Electrode as a Model for Round Window Stimulation by Kiana Kheirkhah, Valerie Van Kelecom, Marc Leblans, Joost van Dinther, Glynnis De Greve, Erwin Offeciers, Andrzej Zarowsk

“…Methods: The study was performed in 10 adult cochlear implant patients showing complete or almost complete tinnitus suppression during electrical stimulation with their standard fitting-MAP. …”
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Lost microbes of COVID-19: Bifidobacterium, Faecalibacterium depletion and decreased microbiome diversity associated with SARS-CoV-2 infection severity by Eamonn MM Quigley, Thomas J Borody, Sabine Hazan, Neil Stollman, Huseyin S Bozkurt, Sonya Dave, Andreas J Papoutsis, Jordan Daniels, Brad D Barrows

“…Objective The study objective was to compare gut microbiome diversity and composition in SARS-CoV-2 PCR-positive patients whose symptoms ranged from asymptomatic to severe versus PCR-negative exposed controls.Design Using a cross-sectional design, we performed shotgun next-generation sequencing on stool samples to evaluate gut microbiome composition and diversity in both patients with SARS-CoV-2 PCR-confirmed infections, which had presented to Ventura Clinical Trials for care from March 2020 through October 2021 and SARS-CoV-2 PCR-negative exposed controls. …”
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A study on the variability and correlation of ocular biological measurement parameters in adult myopic patients by Fangxing Zhou, Nan Chen, Hui Qian, Di Gong, Kunke Li

“…Spearman correlation coefficients were calculated to analyze the correlations between parameters, and linear regression and ROC curve analyses were performed.ResultsSignificant differences (p < 0.05) were found among mild, moderate, and high myopia groups in parameters such as DS, DC, AL, K1, Km, ACD, CRC, and AL/CRC. …”
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Immune status in patients differing in the stage of choroidal melanoma by D.A. Drumi

“…Purpose: To perform a pre-treatment comparison of patients with different stages of choroidal melanoma (CM) for humoral and cell-mediated immune status. …”
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Efficacy and Safety of a Stimulator Using Low-Intensity Pulsed Ultrasound Combined with Transcutaneous Electrical Nerve Stimulation in Patients with Painful Knee Osteoarthritis by Eu-Deum Kim, Yu Hui Won, Sung-Hee Park, Jeon-Hwan Seo, Da-Sol Kim, Myoung-Hwan Ko, Gi-Wook Kim

“…We evaluated visual analogue scale (VAS), Western Ontario and McMaster Universities (WOMAC) osteoarthritis index, MOS 36-Item Short-Form Health Survey (SF-36), and femoral articular cartilage (FAC) thickness. The evaluation was performed at three visits: visit 1 (V1, pretreatment, within 28 days after screening), visit 2 (V2, posttreatment period 1, ±3 days after treatment), and visit 3 (V3, posttreatment period 2, 21 ± 3 days after treatment). …”
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Direct anastomosis indwelling needle puncture: a rapid and safe transitional hemodialysis access for patients with renal failure by Chunyan Wu, Jianbo Qing, Xiaoping Wang, Yunmei Li, Xin Zhou, Junnan Wu

“…Detailed assessments and records of VAT were performed for all patients, including the distance of thrombus from the anastomosis, residual blood flow at the VA anastomosis, and corresponding selection of the DAINP insertion site. …”
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A comparison of new and existing rootstocks to reduce canker of apple trees caused by Neonectria ditissima (Nectriaceae, Hypocreales) by Lucas A. Shuttleworth, Sonia Newman, Ioannis Korkos

“…The industry standard rootstocks M9 EMLA and M9 337 were ranked 12 and 14, and with EMR-001 were the three worst performing rootstocks. The Geneva® rootstocks G11 was ranked 6, and G41 was ranked 11. …”
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Giant Granular Cell Tumor of the Left Thigh, a Rare Case Report and Literature Review by Liu Q, Kong X, Yang J, Zhang D

“…Surgical resection was performed. Microscopic examination revealed round or polygonal tumor cells distributed in sheets or nests, with no evident atypical cells or signs of nuclear division. …”
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Phylogenomic analysis reveals exceptions to the co-evolution of ZAR1 and ZRK immune gene families in plants by Li Yang, Shengyi Liu, M. Eric Schranz, Klaas Bouwmeester

“…To trace the origin and divergence of ZAR1 and ZRK immune gene families across the plant kingdom, we performed phylogenomic analyses using an extended set of plant genomes. …”
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Polyethylene Glycol Loxenatide (PEX-168) Reduces Body Weight and Blood Glucose in Simple Obese Mice by Yuting Wu, Zeyuan Guo, Junlu Wang, Yong Wang, Daorong Wang, Ying Li, Lihua Zhu, Xiaofang Sun

“…Body weight, food intake, and fasting blood glucose (FBG) were evaluated after intraperitoneal injection, and the intervention was performed weekly for 12 weeks. Fasting insulin (FINS) levels were measured at the 12th week. …”
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The 340B Drug Pricing Program and Management of Advanced Prostate Cancer by Kassem S. Faraj, Samuel R. Kaufman, Mary Oerline, Christopher Dall, Arnav Srivastava, Megan E. V. Caram, Vahakn B. Shahinian, Brent K. Hollenbeck

“…Through investment in programs to assist this population, savings generated from the 340B program have the potential to mitigate barriers to initiating treatment with targeted therapies in these men. Methods We performed a retrospective study using a 20% national sample of fee‐for‐service Medicare beneficiaries diagnosed with advanced prostate cancer between 2012 and 2019. …”
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Role of Aging in Ulcerative Colitis Pathogenesis: A Focus on ETS1 as a Promising Biomarker by Ni M, Peng W, Wang X, Li J

“…After identifying UC-related ARGs, consistent clustering was performed to screen aging-related molecular subtypes, followed by the exploration of differences in the immune microenvironment and pathways between distinct subtypes. …”
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Risk, incidence and predictors of venous thromboembolism among patients attending the emergency department of tertiary care hospitals in Addis Ababa city, Ethiopia: a multicentre p... by Desalew Mekonnen, Alemseged Beyene Berha, Worku Degefa, Minyahil Alebachew Woldu

“…Around one-third of patients (130, 30.8%) were unable to perform physical activity, and about two-thirds had comorbid illnesses. …”
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Exploring the mediating role of blood metabolites in the relationship between gut microbiota and gastric cancer risk: a Mendelian randomization study by Xiaocheng Li, Xiaocheng Li, Huapeng Lin, Huapeng Lin, Huapeng Lin, Jing Peng, Jianping Gong

“…However, the causal nature of these associations remains uncertain.MethodsWe utilized summary data from genome-wide association studies (GWAS) on GM (European, n=8,956), blood metabolites (European, n=120,241; East Asian, n=4,435), and GC (European, n=476,116; East Asian, n=167,122) to perform a bidirectional Mendelian randomization (MR) analysis, investigating the causal effects of GM and metabolites on GC risk. …”
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Correlation between METTL3 overexpression and 18F-FDG uptake in patients with soft tissue sarcoma by Tong Wu, Jinghui Xie, Hongbo Feng, Hua Zhang, Juan Tao, Bo Chen

“…Immunohistochemical staining and 18F-FDG radioautography were performed on tumor tissues from 39 patients with STS undergoing 18F-FDG PET before treatment. …”
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Comparison of Ziziphus jujube Mill. Syrup versus polyethylene glycol in children with functional constipation: a randomized clinical trial by Fatemeh Keihanian, Shohreh Maleknejad, Amin Saeidinia, Soheil Soltanipour, Amir Pirooz

“…A double-blind, randomized clinical trial was performed on children aged 2–10 years with functional constipation who were referred to the gastroenterology clinic of the 17-Shahrivar Hospital in Rasht, Iran. …”
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Risk factors for fear of falling in stroke patients: a systematic review and meta-analysis by Li Ma, Qi Xie, Juhong Pei, Ling Gou, Yabin Zhang, Juanping Zhong, Yujie Su, Xinglei Wang, Xinman Dou

“…Meta-regression and Egger’s test were performed by Stata V.15.1. The risk factors for FoF in patients with stroke were women (OR=2.13, 95% CI 1.47 to 3.09), impaired balance ability (OR=5.54; 95% CI 3.48 to 8.81), lower mobility (OR=1.12; 95% CI 1.05 to 1.19), history of falls (OR=2.33; 95% CI 1.54 to 3.53) and walking aid (OR=1.98; 95% CI 1.37 to 2.88), anxiety (OR=2.29; 95% CI 1.43 to 3.67), depression (OR=1.80; 95% CI 1.22 to 2.67), poor lower limb motor function (OR=1.14; 95% CI 1.00 to 1.29) and physically inactiveness (OR=2.04; 95% CI 1.01 to 4.12). …”
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The financial character of policing in Tunisia: collusions, extraversion and the criminalization of informality by Daniela Musina

“…Firstly, it generates a legal expansion of the financial policing assemblage, including in its repressive outcomes, and the making of exception that has to be understood in its performative, experimental and relational character, and not as ontologically absolute. …”
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