The simpler modified fried frailty scale predicts 2-year mortality in older adults with heart failure: a pilot study by Celalettin Küçük, Serdar Özkök, Gülistan Bahat, Ekrem Bilal Karaayvaz, Mustafa Altınkaynak, Alpay Medetalibeyoğlu, Mehmet Akif Karan

“…Cox-regression analysis was performed to identify whether SMFFS-defined frailty could predict mortality in follow-up, with adjusting for a list of clinical characteristics and geriatric syndromes. …”
Get full text

Association of TyG index with mortality at 28 days in sepsis patients in intensive care from MIMIC IV database by Heping Xu, Jinyuan Xie, Yan Xia, Huan Niu, Hong Wang, Feng Zhan

“…Subgroup analyses and sensitivity analyses were performed to further validate the robustness of the results. …”
Get full text

Lymphoadenopathies caused by Bartonella henselae by V.S. Zhukovskiy, O.V. Prokopiv, I.R. Trutyak, M.V. Pankiv

“…In the second case, a subfebrile body temperature, a painful lymph node in the right axillary area for 3 weeks were the reason to perform an invasive surgery twice for diagnosed bacterial process of unknown etiology. …”
Get full text

DYNLT3 overexpression induces apoptosis and inhibits cell growth and migration via inhibition of the Wnt pathway and EMT in cervical cancer by Jianan Zhang, Qi Shen, Lu Xia, Xueqiong Zhu, Xuejie Zhu

“…Furthermore, the effects of DYNLT3 on the tumorigenicity and metastasis of cervical cancer in nude mice were analyzed by performing immunohistochemistry, and we found that the expression level of the DYNLT3 protein was higher in human normal cervical tissues than in cervical cancer tissues. …”
Get full text

Circadian clock regulation in soybean senescence: a transcriptome analysis of early and late senescence types by Prakash Basnet, Sevin Lee, Ka Hee Moon, Nam-Il Park, Gang-Seob Lee, Seongkon Lee, Taeyoung Um, Ik-Young Choi

“…To understand the molecular mechanisms underlying this senescence, we performed transcriptome analysis of leaves from 50 to 95 DAS of ES- and LS-type plants. …”
Get full text

Mechanism of Spica Prunellae in Suppressing Proliferation and Stem Cell Properties of Colorectal Cancer Cells Based on Notch Signaling Pathway by TIAN Haoyuan, XIE Yi, FANG Yi, CHENG Ying, LIN Yan, SU Daifeng, WEI Lihui

“…After 24 hours of intervention, the subsequent experiments were performed. The cell growth morphology and density were observed by inverted microscope. …”
Get full text

PSA LEVEL AND ADVERSE EVENTS IN SIXTH AND TENTH SERIES DOCETAXEL CHEMOTHERAPY IN CASTRATE-RESISTANT PROSTATE CANCER (CRPC) PATIENTS by Kurnia Penta Seputra, Andri Kustono, Muhammad Baihaqy Ibnu Hakim

“…Statistical analysis was performed using a differential T-test. Results: A total of 32 participants were involved. …”
Get full text

Near-infrared spectroscopy combined with vascular occlusion test to predict acute kidney injury in patients undergoing cardiac surgery: a prospective observational study by Ling Peng, Yeying Zheng, Fei Guo, Mengdan Su, Wei Wei

“…StO2 was continuously monitored at the right forearm and ipsilateral VOT procedure was performed before initiation of CPB, at the time before weaning from CPB, and at the end of surgery. …”
Get full text

Migraine and subsequent chronic kidney disease risk: a nationwide population-based cohort study by Ming-Ju Wu, Chew-Teng Kor, Chia-Chu Chang, Shuo-Chun Weng, Chia-Lin Wu, Ping-Fang Chiu, Der-Cherng Tarng

“…All the participants were registered in the National Health Insurance Research Database.Participants Finally, data from 7156 subjects with migraine and 7156 propensity-score-matched control subjects were analysed.Primary outcome measure We used Cox proportional hazards regression to estimate adjusted HRs for incident CKD; subgroup analyses were performed to assess the interactive effects of migraine with demographics, comorbidities and long-term medications.Results The incidence of CKD was higher in the migraine group than in the control group. …”
Get full text

Profiles of physician follow-up care, correlates and outcomes among patients affected by an incident mental disorder by Marie-Josée Fleury, Louis Rochette, Zhirong Cao, Guy Grenier, Victoria Massamba, Alain Lesage

“…Latent class analysis was performed to identify follow-up care profiles, mostly within one year of MD detection. …”
Get full text

Idiopathic pulmonary fibrosis is a risk factor for cardiovascular disease: potential role of KL-6 and systemic inflammation by Mohamed F. AbdelGhany, Waleed GamalEldin Khaleel, Asmaa Omar Ahmed, Ahmad BaheyElden Ahmed, Lamees M. Bakkar

“…Methods This prospective case–control study was performed on 134 IPF patients above 18 years. Diagnosis of IPF was based on diagnostic radiologic criteria addressed by ATS guidelines. …”
Get full text

Comparative transcriptome and metabolome analysis of sweet potato (Ipomoea batatas (L.) Lam.) tuber development by Yanhui Lin, Yapeng Li, Yapeng Li, Honglin Zhu, Liqiong Tang, Jing Xu

“…IntroductionSweet potato is an important food, feed and industrial raw material, and its tubers are rich in starch, carotenoids and anthocyanins.MethodsTo elucidate the gene expression regulation and metabolic characteristics during the development of sweet potato tubers, transcriptomic and metabolomic analyses were performed on the tubers of three different sweet potato varieties at three developmental stages (70, 100, and 130 days (d)).ResultsRNA-seq analysis revealed that 16,303 differentially expressed genes (DEGs) were divided into 12 clusters according to their expression patterns, and the pathways of each cluster were annotated. …”
Get full text

Propofol Priming for Enhancing Induction Safety in Hypertensive Patients: A Prospective Double-blind Randomised Controlled Trial by Tarun Yadav, Mayuri Golhar, Chhavi Saini

“…Materials and Methods: This prospective, comparative, double-blind randomised controlled trail was performed at the Department of Anaesthesiology, Pt. …”
Get full text

Long noncoding RNA Gm4419 promotes mesangial cell proliferation and extracellular matrix accumulation via the miR-455-3p/histone deacetylase 2 axis by Yang Wen, Hua Gan, Qing Zhong, Ying Gong

“…Cell transfection, fluorescence in situ hybridization, RNA immunoprecipitation, and dual luciferase reporter assay were also performed. Our results revealed significant cell proliferation and extracellular matrix accumulation in high glucose-treated mesangial cells. …”
Get full text

Modern Contraceptive Use and Influencing Factors in Amhara Regional State: Further Analysis of Ethiopian Demographic Health Survey Data 2016 by Melash Belachew Asresie, Gedefaw Abeje Fekadu, Gizachew Work Dagnew, Yared Mulu Gelaw

“…Both descriptive and logistic regression analyses were performed using STATA V.14. A 95% confidence interval was used to declare statistical significance. …”
Get full text

Huanglian Ejiao Decoction Alleviates Ulcerative Colitis in Mice Through Regulating the Gut Microbiota and Inhibiting the Ratio of Th1 and Th2 Cells by Tang J, Hu Y, Fang J, Zhu W, Xu W, Yu D, Zheng Z, Zhou Q, Fu H, Zhang W

“…Transcriptome sequencing was performed on colon tissue and 16S rRNA gene sequencing was enforced on intestinal contents.Results: The administration of HED enhanced the survival rate of colitis mice, significantly restored body weight, DAI score, colon weight and index, spleen weight and index. …”
Get full text

Recent trends in research on the role of cholesterol in leukemia: a bibliometric and visualization study by Huijuan Lv, Ke Lu, Ximing Wang, Yanfang Zhang, Mengqi Zhuang, Jing Li, Keli Su, Wen Gao

“…This study employs bibliometric analysis and visualization techniques to investigate research trends regarding cholesterol in leukemia and identify key hotspots.MethodsA systematic search of the Web of Science Core Collection was performed for literature published from 1980 to 2024 using the keywords “cholesterol” and “leukemia,” yielding 1,220 articles. …”
Get full text

SARS-CoV-2 infection rates and associated risk factors in healthcare workers: systematic review and meta-analysis by Amit Bansal, Mai-Chi Trieu, Emily M. Eriksson, Fan Zhou, Jodie McVernon, Karl Albert Brokstad, Rebecca Jane Cox

“…Household exposure (odds ratio (OR) 7.07; 95% CI 3.93–12.73), working as a cleaner (OR 2.72; 95% CI 1.39–5.32), occupational exposure (OR 1.79; 95% CI 1.49–2.14), inadequate training on infection prevention and control (OR 1.46; 95% CI 1.14–1.87), insufficient use of personal protective equipment (OR 1.45; 95% CI 1.14–1.84), performing aerosol generating procedures (OR 1.36; 95% CI 1.21–1.52) and inadequate hand hygiene (OR 1.17; 95% CI 0.79–1.73) were associated with an increased SARS-CoV-2 infection. …”
Get full text

Development and experimental validation of dephosphorylation-related biomarkers to assess prognosis and immunotherapeutic response in gliomas by Hui Tang, Xuping Yang, Xuping Yang, Guoqian Li, Ke Peng, Yang Sun, Longyang Jiang, Longyang Jiang, Yilan Huang, Yilan Huang

“…Gene set enrichment analysis (GSEA), immune cell infiltration, immunotherapy response and chemotherapeutic drug sensitivity analysis were performed in this study. The correlation between chemotherapeutic drugs and the half maximal inhibitory concentration (IC50) values of 12 DRGs was analyzed. …”
Get full text

Effect of conservative treatment on greater trochanteric pain syndrome: a systematic review and network meta-analysis of randomized controlled trials by Si-Qi Wang, Ning-Yi Guo, Wei Liu, Hong-jie Huang, Bing-bing Xu, Jian-quan Wang

“…Network meta-analysis was performed using random effects models to evaluate the effects of treatment modalities on pain reduction and functional improvement. …”
Get full text