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1361
Biomarkers predicting postoperative adverse outcomes in children with congenital heart disease: a systematic review and meta-analysis
Published 2025-01-01“…Lower postoperative N-terminal pro-B-type natriuretic peptide (NT-pro BNP) levels were associated with lower mortality (OR: 0.23, 95% CI: 0.08–0.68) and shorter mechanical ventilation time (OR: 0.40, 95% CI: 0.18–0.90). …”
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1362
Review: Application of Protein-Based Raw Materials in Health Foods in China
Published 2024-12-01“…In short, through data analysis, this study found that in 1996~2024, a total of 1142 health foods containing raw protein materials were approved in China, which are mainly divided into animal proteins, vegetable proteins, microbial proteins, and peptide raw materials, and peptide raw materials comprise the majority. …”
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1363
Significance of single-nucleotide variants of anorexigenic hormone genes in childhood obesity
Published 2024-04-01“…The aim of the study was to determine the level of association of single-nucleotide variants of genes that determine eating behavior – Neuronal growth regulator 1, Fat mass and obesity associated gene, Glucagon-like peptide-1 receptor, ghrelin, leptin receptor, cholecystokinin, in the development of metabolically unhealthy obesity. 252 obese children aged 6-18 years were examined. …”
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1364
The efficacy of cholecalciferol in the comprehensive treatment of patients with autoimmune diabetes
Published 2024-12-01“…Particularly significant was an increase in C-peptide levels observed in patients with LADA, reflecting enhanced β-cell function in the pancreas. …”
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1365
Chemokines and Chemokine Receptors in Multiple Sclerosis
Published 2014-01-01“…Chemokines, which are small peptide mediators, can attract pathogenic cells to the sites of inflammation. …”
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1366
Turnour necrosis factor stimulates endothelin-1 gene expression in cultured bovine endothelial cells
Published 1992-01-01“…TNF-α induced endothelin-1 gene expression was associated with a parallel increase in the release of the corresponding peptide in the culture medium. These findings suggest that the enhanced synthesis and release of endothelin-1 occurring in conditions of increased generation of TNF, may act as a modulatory factor that counteracts the hypotensive effect and the excessive platelet aggregation and adhesion induced by TNF.…”
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1367
The Potential of Single-Chain Variable Fragment Antibody: Role in Future Therapeutic and Diagnostic Biologics
Published 2024-01-01“…Genes of variable regions, the heavy and light chains that are genetically linked into a single transcript by a short flexible linker peptide, are used to generate this fragment from cellular and synthetic libraries. …”
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1368
Targeting the Hepcidin-Ferroportin Axis in the Diagnosis and Treatment of Anemias
Published 2010-01-01“…The hepatic peptide hormone hepcidin regulates dietary iron absorption, plasma iron concentrations, and tissue iron distribution. …”
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1369
Alpha-Fetoprotein and Hepatocellular Carcinoma Immunity
Published 2018-01-01“…AFP-modified immune cell vaccine or peptide vaccine has displayed the specific antitumor immunity against AFP-positive tumor cells and laid a better foundation for the immunotherapy of liver cancer.…”
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1370
Oxytocin in the Treatment of Psychiatric Disorders
Published 2023-09-01“…Oxytocin is a peptide hormone that is most known for its role in reproduction. …”
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1371
An electronic tongue system with automatic sample mixing function for long-term in-situ monitoring of chemical reactions
Published 2025-01-01“…Proven effective in studying nucleotide selection and amino acid regulation during peptide formation, this device broadened the possibilities of automated monitoring designs and was deployed in the Wentian module of Tiangong space station, advancing the application prospects of the electronic tongue system in space chemistry.…”
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1372
Solid-Phase Extraction Strategies to Surmount Body Fluid Sample Complexity in High-Throughput Mass Spectrometry-Based Proteomics
Published 2015-01-01“…Various sample preparation methods that involve solid-phase extraction (SPE) including affinity enrichment strategies have been automated. Obtained peptide and protein fractions can be mass analyzed by direct infusion into an electrospray ionization (ESI) source or by means of matrix-assisted laser desorption ionization (MALDI) without further need of time-consuming liquid chromatography (LC) separations.…”
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1373
Aggrephagy: Selective Disposal of Protein Aggregates by Macroautophagy
Published 2012-01-01“…The aggregates can be degraded by the proteasome and by chaperone-mediated autophagy only after dissolution into soluble single peptide species. Hence, protein aggregates as such are degraded by macroautophagy. …”
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1374
Iatrogenic cerebral amyloid angiopathy and Alzheimer's disease co‐pathology
Published 2025-01-01“…Abstract Iatrogenic cerebral amyloid angiopathy, a disease caused by contact with neurosurgical material or human growth hormone contaminated by beta‐amyloid peptide (Aβ), has a prion‐like transmission mechanism. …”
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1375
Characteristics and Determinants of Partial Remission in Children with Type 1 Diabetes Using the Insulin-Dose-Adjusted A1C Definition
Published 2014-01-01“…We show that, at diagnosis of T1D, parameters associated with β-cell mass reserve (A1C, C-peptide, and DKA) correlate with the occurrence of PR, which affects post-PR A1C levels. …”
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1376
Comparative efficacy of different drugs in acute heart failure with renal dysfunction: a systematic review and network meta-analysis
Published 2025-01-01“…The primary outcome measures were N-terminal pro-B type natriuretic peptide (NT-proBNP), B-type natriuretic peptide (BNP), glomerular filtration rate (GFR), blood urea nitrogen, serum creatinine, all-cause mortality within 60 days, and cardiovascular mortality.ResultsAfter screening 30,697 citations, 13 studies (21,745 patients) were included, and drugs including nesiritide, dopamine, tolvaptan, levosimendan, dobutamine, furosemide, and spirolactone, and high dose of diuretics (HDD, furosemide, and spirolactone) were estimated. …”
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1377
The ABC transporter A7 modulates neuroinflammation via NLRP3 inflammasome in Alzheimer’s disease mice
Published 2025-01-01“…ABCA7 transports lipids from/across cell membranes, regulates Aβ peptide processing and clearance, and modulates microglial and T-cell functions to maintain immune homeostasis in the brain. …”
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1378
The sexually dimorphic expression of glutamate transporters and their implication in pain after spinal cord injury
Published 2025-11-01“…Analyses of peptidergic (calcitonin gene-related peptide-α) and non-peptidergic (isolectin B4) fibers outgrowth in the dorsal horn after spinal cord injury showed an increased calcitonin gene-related peptide-α/ isolectin B4 ratio in comparison with sham, suggesting increased receptive fields in the dorsal horn. …”
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1379
The Role of RaxST, a Prokaryotic Sulfotransferase, and RaxABC, a Putative Type I Secretion System, in Activation of the Rice XA21-Mediated Immune Response
Published 2014-01-01“…These observations suggest a model where RaxST sulfates a molecule that contains a leader peptide, which is cleaved by the peptidase domain of the RaxB protein and secreted outside the bacterial cell by the RaxABC T1SS.…”
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1380
Hexapeptide dalargin in clinical gastroenterology: 30 years' of clinical application of the drug
Published 2016-08-01“…Dalargin is the first synthetic opioid peptide agent created on the basis of endogenous leucineenkephaline. …”
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