Blood-based biomarkers and plasma Aβ assays in the differential diagnosis of Alzheimer’s disease and behavioral-variant frontotemporal dementia by Pablo Mohaupt, Jana Kindermans, Jérôme Vialaret, Sarah Anderl-Straub, Leonie Werner, Sylvain Lehmann, Christophe Hirtz, Markus Otto, Patrick Oeckl

“…Methods We devised a novel assay combining immunoprecipitation and mass spectrometry (IP-MS) to quantify Amyloid-beta (Aβ) peptides in plasma. We then assessed its performance against existing assays (Shimadzu and Simoa) and evaluated a range of other blood-based biomarkers, including GFAP, NfL, and pTau-181, for differentiating between AD and bvFTD. …”
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Pseudomonas azotoformans and Pseudomonas putida: Novel kiwifruit-native biological control agents against Pseudomonas syringae pv. actinidiae by Cristiana Correia, Antonio Cellini, Irene Donati, Panagiotis Voulgaris, Adebayo Ebenezer Obafemi, Elia Soriato, Elodie Vandelle, Conceição Santos, Francesco Spinelli

“…Moreover, several biosynthetic gene clusters of secondary metabolites, were predicted in the genome of both strains, including non-ribosomal peptides, and the bacteriocin pyocin was predicted in the genome of BG1. …”
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iTRAQ-based quantitative proteomic analysis of herbicide stress in Avena ludoviciana Durieu by Hossein Adim, Leila Fahmideh, Barat Ali Fakheri, Hamid Najafi Zarrini, Hamidreza Sasanfar

“…In this study, a total of 18,313 peptides were identified with ≤ 0.01 FDR, which could be classified into 484 protein groups. …”
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Impact of eggshell membrane on metabolism and cell adhesion in oxidatively stressed canine chondrocytes by Juraj Vozar, Nikola Hudakova, Natalia Nosalova, Mykhailo Huniadi, Dana Marcincakova, Slavomir Hornak, Lubica Hornakova, Petra Majerova, Dasa Cizkova, Dasa Cizkova

“…Eggshell membrane (ESM) is a rich source of bioactive compounds, including proteins, peptides, and antioxidants, contributing to its potential therapeutic benefits. …”
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Health benefits of algae and marine-derived bioactive metabolites for modulating ulcerative colitis symptoms by Najmeh Oliyaei, Saghar Zekri, Aida Iraji, Alireza Oliyaei, Romina Tanideh, Nadiar M. Mussin, Amin Tamadon, Nader Tanideh

“…It has been reported that algal sulfated polysaccharides, peptides, pigments, polyphenols, and marine oil are useful for controlling ulcerative colitis via different pathways including modulating of TNF-α and other related inflammatory cytokines secretion, increasing the antioxidant enzymes [superoxide dismutase (SOD) and catalase(CAT)] activities, reduction of myeloperoxidase (MPO) activity and malondialdehyde (MDA) production, improving the intestinal barrier function and repairing histological damage in the colon. …”
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The MSDIN family in amanitin-producing mushrooms and evolution of the prolyl oligopeptidase genes by Hong Luo, Qing Cai, Yunjiao Lüli, Xuan Li, Rohita Sinha, Heather E. Hallen-Adams, Zhu L. Yang

“…Abstract The biosynthetic pathway for amanitins and related cyclic peptides in deadly Amanita (Amanitaceae) mushrooms represents the first known ribosomal cyclic peptide pathway in the Fungi. …”
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Exploring the Mechanism of <i>Clostridium autoethanogenum</i> Protein for Broiler Growth Based on Gut Microbiota and Serum Metabolomics by Chunqiao Shan, Yan Liu, Sisi Liu, Chuang Li, Chaoxin Ma, Hongmin Yu, Juan Li, Guotuo Jiang, Jing Tian

“…Metabolomic analyses indicated that the effect of incorporating CAP into the diet on serum metabolites primarily focused on organic acids and their derivatives, small peptides, amino acid derivatives, and oxidized lipids. …”
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Mapping knowledge landscapes and emerging trends in artificial intelligence for antimicrobial resistance: bibliometric and visualization analysis by Zhongli Wang, Zhongli Wang, Gaopei Zhu, Shixue Li, Shixue Li

“…Keyword analysis identified six enduring research clusters from 2014 to 2024: sepsis, artificial neural networks, antimicrobial resistance, antimicrobial peptides, drug repurposing, and molecular docking, demonstrating the sustained integration of AI in antimicrobial therapy development. …”
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Towards more efficient, more specific, and safer MRI contrast agents: a Portuguese–French collaborative journey by Pinto, Sara Martinho Almeida, Lacerda, Sara, Morfin, Jean-François, Aroso, Rafael Tiago,  Teixeira, Daniela Sofia de Sousa, Garda, Zoltán, Pereira, Maria Miguens,  Geraldes, Carlos Frederico Gusmão Campos, Tóth, Éva

“…For the specific targeting of amyloid peptides implicated in many pathologies such as Alzheimer’s disease and diabetes, they have designed benzothiazole-derivative metal chelates with detection potential in MRI, optical, and nuclear imaging modalities. …”
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Structural and functional features of phytoene synthase isoforms PSY1 and PSY2 in pepper Capsicum annuum L. cultivars by E. A. Dyachenko, M. A. Filyushin, G. I. Efremov, E. A. Dzhos, A. V. Shchennikova, E. Z. Kochieva

“…All identified PSY1 and PSY2 homologs contained the phytoene synthase domain HH-IPPS and the transit peptide. In the PSY1 and PSY2 HH-IPPS domains, functionally significant sites were determined. …”
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Two-hit mouse model of heart failure with preserved ejection fraction combining diet-induced obesity and renin-mediated hypertension by Justin H. Berger, Yuji Shi, Timothy R. Matsuura, Kirill Batmanov, Xian Chen, Kelly Tam, Mackenzie Marshall, Richard Kue, Jiten Patel, Renee Taing, Russell Callaway, Joanna Griffin, Attila Kovacs, Dinesh Hirenallur-Shanthappa, Russell Miller, Bei B. Zhang, Rachel J. Roth Flach, Daniel P. Kelly

“…HFD-Renin (aka “HFpEF”) mice demonstrated obesity and insulin resistance, moderate left ventricular hypertrophy, preserved systolic function, and diastolic dysfunction indicated by echocardiographic measurements; increased left atrial mass; elevated natriuretic peptides; and exercise intolerance. Transcriptomic and metabolomic profiling of HFD-Renin myocardium demonstrated upregulation of pro-fibrotic pathways and downregulation of metabolic pathways, in particular branched chain amino acid catabolism, similar to human HFpEF. …”
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Lower Plasma β-Amyloid 1-42 Levels in Amnestic Mild Cognitive Impairment Compared to Healthy Individuals by Cynthia Cynthia, Jusak Nugraha, Muhammad Hamdan, Hari Basuki Notobroto, Silvia Francina Lumempouw, Rahajuningsih Dharma

“…KEYWORDS: blood biomarkers, amyloid beta peptides, amnestic mild cognitive impairment (aMCI)…”
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Accumulation and distribution of cadmium at organic-mineral micro-interfaces across soil aggregates by Qi Li, Linfeng Li, Bohao Yin, Xiaoyang Lin, Anwen Xiao, Weijie Xue, Hengjie Liu, Yichun Li

“…Additionally, the mineral and microbial amendments reduced the binding of Fe oxides with microbial-derived peptides in the macroaggregates and enhanced the interaction of Fe oxides with plant-derived lignin in the silt+clay fractions. …”
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A wheat germ-rich diet preserves bone homeostasis by regulating gut microbiota and plasma metabolites in aged rats by Luanfeng Wang, Zebin Weng, Tong Chen, Yu Li, Ling Xiong, Haizhao Song, Fang Wang, Xiaozhi Tang, Bo Ren, Xuebo Liu, Xinchun Shen

“…Wheat germ (WG) is consists of high amounts of bioactive peptides, polyunsaturated fatty acids, and dietary fibre. …”
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Antimicrobial Activity and Mode of Action of N-Heterocyclic Carbene Silver(I) Complexes by Giusy Castagliuolo, Michela Di Napoli, Tshering Zangmo, Joanna Szpunar, Luisa Ronga, Anna Zanfardino, Mario Varcamonti, Diego Tesauro

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Analysis of quality-related proteins in golden pompano (Trachinotus ovatus) fillets with modifi ed atmosphere packaging under superchilling storage by Chuang Pan, Xiaofan Zhang, Shengjun Chen, Yong Xue, Yanyan Wu, Yueqi Wang, Di Wang

“…Total sulfhydryl content, TCA-soluble peptides and Ca2+-ATPase activity also showed that the fillet protein had a deterioration by oxidation and denaturation. …”
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Valorisation of shell waste of invasive crayfish from Danube River (Faxonius limosus): Protein extraction and characterization by Hromiš Nevena M., Popović Senka Z., Šuput Danijela Z., Pantić Jovana R., Rakita Slađana M., Tomičić Zorica M., Čabarkapa Ivana S.

“…The DPPH assay revealed high antioxidant activity of the concentrates (72.00-88.06 %), probably originating from active peptides derived from proteins and residual carotenoids, mainly astaxanthin.…”
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A Review of Marine Bacterial Intracellular and Extracellular Bioactive Compounds as Novel Antibacterial and Anti-Inflammation Agents by Harningsih Karim, Arief Azis, Ananda Ramadani, Anita Anita, Ahyar Ahmad, Hasnah Natsir, Paulina Taba, Suriati Eka Putri, Sarlan Sarlan, Siti Halimah Larekeng, Rizal Irfandi

“…A crucial resource in the ongoing search for novel peptides, proteins, lipids, nucleosides, enzymes, alkaloids, polyketides, and terpenoids is the diversity of marine bacterium strains. …”
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First whole genome report of Mangrovibacter phragmitis PSU-3885–11 isolated from a patient in Thailand by Nattarika Chaichana, Thunchanok Yaikhan, Mingkwan Yingkajorn, Nonthawat Thepsimanon, Sirikan Suwannasin, Kamonnut Singkhamanan, Sarunyou Chusri, Rattanaruji Pomwised, Monwadee Wonglapsuwan, Komwit Surachat

“…The presence of ribosomally synthesized and post-translationally modified peptides (RiPPs) and bacteriocins indicates the antimicrobial properties that may provide a competitive advantage in both environmental and clinical settings of this strain. …”
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Reduced Expression of Antimicrobial Protein Secretory Leukoprotease Inhibitor and Clusterin in Chronic Rhinosinusitis with Nasal Polyps by Yanran Huang, Ming Wang, Yu Hong, Xiangting Bu, Ge Luan, Yang Wang, Ying Li, Hongfei Lou, Chengshuo Wang, Luo Zhang

“…Introduction. Antimicrobial peptides and proteins (AMPs) constitute the first line of defense against pathogenic microorganisms in the airway. …”
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