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1021
HLA Class II Defects in Burkitt Lymphoma: Bryostatin-1-Induced 17 kDa Protein Restores CD4+ T-Cell Recognition
Published 2011-01-01“…We further demonstrate that BL cells express the components of the class II pathway, and the defect was not caused by faulty Ag/class II interaction, because antigenic peptides bound with measurable affinity to BL-associated class II molecules. …”
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1022
Probiotic Bacterium-Derived p40, p75, and HM0539 Proteins as Novel Postbiotics and Gut-Associated Immune System (GAIS) Modulation: Postbiotic-Gut-Health Axis
Published 2024-12-01“…Postbiotics are bioactive metabolites such as organic acids, peptides/proteins, cell wall components, functional enzymes, short-chain fatty acids, vitamins, and phenols. …”
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1023
Identification of TTLL8, POTEE, and PKMYT1 as immunogenic cancer-associated antigens and potential immunotherapy targets in ovarian cancer
Published 2025-12-01“…From this dataset, we identified TTLL8, POTEE, and PKMYT1 peptides as candidate tumor antigens with low expression in normal tissues and upregulated expression in OC. …”
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1024
Beneficial effects of high-pressure homogenization on the dispersion stability of aqueous hydrolysate from Mytilus edulis
Published 2020-12-01“…Owing to the formation of aggregation and gelation during storage, certain proteins and peptides exhibit limited applications in aqueous protein food products. …”
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1025
Effects of brain renin- angiotensin system inhibition in ISIAH rats with inherited stress-induced arterial hypertension
Published 2017-11-01“…The renin-angiotensin system (RAS) is one of the main systems regulating arterial pressure and water-salt homeostasis of the body and is involved in the pathogenesis of cardiovascular diseases. Angiotensin peptides – products of enzymatic hydrolysis of angiotensinogen – can be synthesized not only in the blood stream, but also in tissues, including various regions of the brain. …”
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1026
The gut microbiota‐derived metabolite indole‐3‐propionic acid enhances leptin sensitivity by targeting STAT3 against diet‐induced obesity
Published 2024-12-01“…High‐fat diet (HFD), rather than genetic factors, induces excessive secretion of antimicrobial peptides by Paneth cells, inhibiting the growth of Clostridia in the gut and resulting in decreased production of the beneficial metabolite IPA. …”
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1027
Engineered a dual-targeting biomimetic nanomedicine for pancreatic cancer chemoimmunotherapy
Published 2022-02-01“…To this end, we developed a biomimetic dual-targeting nanomedicine (PG@KMCM) where gemcitabine-loaded poly (lactic-co-glycolic acid) (PLGA) nanoparticles are coated with a layer of bioengineered cancer cell membrane that stably expresses peptides targeting M2-like macrophages (M2pep) while reserving tumor-associated antigens (TAAs). …”
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1028
Marine natural products as an important source of bioactive substances for non-alcoholic fatty liver disease management
Published 2025-01-01“…Marine bioactive substances from natural products, such as polysaccharides, polyphenols, polyunsaturated fatty acids, and peptides, have been shown to benefit liver health by alleviating metabolic dysfunction through multiple mechanisms. …”
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1029
Serological diagnosis of soil-transmitted helminth (Ascaris, Trichuris and hookworm) infections: A scoping review.
Published 2024-04-01“…Almost all records targeted antibodies as analytes, employing proteins and peptides as analyte detection agents. Approximately 60% of sample sets described pertained to human samples. …”
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1030
Cross-sectional study of proteomic differences between moderate and severe psoriasis
Published 2025-01-01“…The main active pathways were antimicrobial peptides and PTEN signalling, while the inhibitory pathways were the neutrophil extracellular trap pathway, neutrophil degranulation, and IL-8 signalling. 4D-parallel reaction monitoring (4D-PRM) suggested that KRT6A were downregulated in severe psoriasis. …”
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1031
Differential proteome analysis of pea roots at the early stages of symbiosis with nodule bacteria
Published 2018-04-01“…To identify the proteins, a mass spectrometric analysis of tryptic peptides was performed on a quadrupole-time-of-flight mass spectrometer combined with a high-performance liquid chromatograph. …”
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1032
Adipokines in Breast Cancer: Decoding Genetic and Proteomic Mechanisms Underlying Migration, Invasion, and Proliferation
Published 2025-01-01“…Anne Ließem, Uwe Leimer, Günter K Germann, Eva Köllensperger Clinic for Plastic, Aesthetic and Reconstructive Surgery, Spine, Orthopedic and Hand Surgery, Preventive Medicine – ETHIANUM, Heidelberg, 69115, GermanyCorrespondence: Eva Köllensperger, Clinic for Plastic, Aesthetic and Reconstructive Surgery, Spine, Orthopedic and Hand Surgery, Preventive Medicine – ETHIANUM, Heidelberg, 69115, Germany, Email Eva.Koellensperger@ethianum.deBackground: Adipokines, bioactive peptides secreted by adipose tissue, appear to contribute to breast cancer development and progression. …”
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1033
Biofunctional Characterization of Collagen from Orange-Spotted Grouper, <i>Epinephelus coioides</i>: Maintenance of Cartilage in Aged Zebrafish
Published 2024-12-01“…The enzymatic hydrolysis of fin-derived collagen using pepsin yielded low-molecular-weight peptides (PHC), which were subsequently incorporated into the diet of 1.5-year-old zebrafish, either alone or in combination with glucosamine (GC), to assess their biological effects. …”
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1034
Importance of Cheese Whey Processing: Supplements for Sports Activities – a Review
Published 2019-01-01“…Whey protein (WP) is a highly nutritious, commercially available alternative food source that is used primarily as a food supplement by athletes and physically active individuals to provide them with essential amino acids and bioactive peptides, and additional benefits have been attributed to WP consumption. …”
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1035
Cottonseed Meal Protein Hydrolysate Improves the Growth Performance of Chinese Mitten Crab (Eriocheir sinensis) by Promoting the Muscle Growth and Molting Performance
Published 2023-01-01“…Plant protein hydrolysates contain a large number of small peptides and free amino acids, which can improve the growth performance of aquatic animals. …”
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1036
Proline‐Selective Electrochemiluminescence Detecting a Single Amino Acid Variation Between A1 and A2 β‐Casein Containing Milks
Published 2025-02-01“…Abstract The proline amino acid and prolyl residues of peptides/proteins confer unique biological and biochemical properties that motivates the development of proline‐selective analysis. …”
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1037
Controversial Roles of Regenerating Family Proteins in Tissue Repair and Tumor Development
Published 2024-12-01“…Successively, short peptides derived from Reg3δ and Reg3α have been employed in clinical trials, showing favorable therapeutic effects in patients with type I and type II diabetes. …”
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1038
Elevated Concentration of Defensins in Hepatitis C Virus-Infected Patients
Published 2016-01-01“…Defensins, small cysteine-rich cationic peptides, are shown to have potent antibacterial, antiviral, and antifungal properties. …”
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1039
Non-specific effect of double-stranded RNAs on Egyptian broomrape (Phelipanche aegyptiaca) seed germination
Published 2025-01-01“…While the effect of biomaterials such as amino acids and microRNA-encoded peptides have been explored, the effect of double-stranded RNAs (dsRNAs) has remained unexamined during the germination process. …”
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1040
The future of plant lectinology: Advanced technologies and computational tools
Published 2025-01-01“…Phage display libraries enable the identification of carbohydrate-mimetic peptides and the development of ligands for lectins by presenting diverse peptide libraries on bacteriophages. …”
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