-
941
Recent Advances in Natural Products Derived from Marine Echinoderms and Endophytic Microbes: Chemical Insights and Therapeutic Potential
Published 2025-01-01“…These metabolites, including polysaccharides, triterpenoids, steroids, and peptides, demonstrate potent bioactivities such as anticancer, anti-inflammatory, antiviral, and antimicrobial effects, providing valuable insights and scaffolds for drug discovery. …”
Get full text
Article -
942
Microalgal proteins as ingredients for creating dairy mimetic products: Prospects for substituting bovine milk proteins
Published 2025-06-01“…Notably, calcium-chelating peptides from microalgae offer osteogenic benefits, highlighting a key health advantage. …”
Get full text
Article -
943
Treatment of the Induration of the Soft Tissue of the Lower Eyelids After Accidental Oil Injections
Published 2025-01-01“…Various substances are injected into the periorbital region for skin quality increase and correction of tear trough deformity, including hyaluronic acid, peptides, collagen, and others. Sometimes patients get accidentally injected with different substances that are not approved for cosmetic treatment in this anatomic area. …”
Get full text
Article -
944
Polyaminated, acetylated and stop codon readthrough of recombinant Francisella tularensis universal stress protein in Escherichia coli.
Published 2024-01-01“…To determine the source of the higher molecular weight for rUsp/His6, post translational modifications were examined. Tryptic peptides of purified rUsp/His6 were subjected to liquid chromatography tandem mass spectrometry (LC-MS/MS) and fragmentation spectra were searched for acetylated lysines and polyaminated glutamines. …”
Get full text
Article -
945
A new crustin-like gene from the redclaw crayfish Cherax quadricarinatus and its response to decapod iridescent virus 1 (DIV1) challenge
Published 2025-01-01“…Crustin, a widely-studied antimicrobial peptides (AMPs), has been proven to be involved in mediating innate immune responses against intruding pathogens. …”
Get full text
Article -
946
Regulation and Roles of Urocortins in the Vascular System
Published 2012-01-01“…Urocortins (Ucns) are members of the corticotropin-releasing factor (CRF) family of peptides. Ucns would have potent effects on the cardiovascular system via the CRF receptor type 2 (CRF2 receptor). …”
Get full text
Article -
947
BACE1 Is Necessary for Experience-Dependent Homeostatic Synaptic Plasticity in Visual Cortex
Published 2014-01-01“…Alzheimer’s disease (AD) is the most common form of age-related dementia, which is thought to result from overproduction and/or reduced clearance of amyloid-beta (Aβ) peptides. Studies over the past few decades suggest that Aβ is produced in an activity-dependent manner and has physiological relevance to normal brain functions. …”
Get full text
Article -
948
PG102 Upregulates IL-37 through p38, ERK, and Smad3 Pathways in HaCaT Keratinocytes
Published 2019-01-01“…It was found that knockdown of IL37 resulted in the augmented expression of antimicrobial peptides (AMPs) in response to cytokine stimulation. …”
Get full text
Article -
949
Lipoprotein Nanoplatform for Targeted Delivery of Diagnostic and Therapeutic Agents
Published 2008-03-01“…A semisynthetic nanoparticle has been constructed by coating magnetite iron oxide nanoparticles with carboxylated cholesterol and overlaying a monolayer of phospholipid to which apolipoprotein A1 or E was adsorbed for targeting HDL or adsorbing synthetic amphipathic helical peptides ltargeting LDL or folate receptors. These particles can be used for in situ loading of magnetite into cells for MRI-monitored cell tracking or gene expression.…”
Get full text
Article -
950
Adrenomedullin as a Growth and Cell Fate Regulatory Factor for Adult Neural Stem Cells
Published 2012-01-01“…An emerging molecule involved in this process is adrenomedullin (AM). AM, a 52-amino acid peptide which exerts a plethora of physiological functions, acts as a growth and cell fate regulatory factor for adult neural stem and progenitor cells. …”
Get full text
Article -
951
Canine Leishmaniasis in Brazil: Serological Follow-Up of a Dog Population in an Endemic Area of American Visceral Leishmaniasis
Published 2009-01-01“…By WB, it was observed that the same percentage and sera from positive dogs presented the recognition of the peptides of 29 and 32 kDa up to 8 months before IFA serum conversion. …”
Get full text
Article -
952
A Chromosome level assembly of pomegranate (Punica granatum L.) variety grown in arid environment
Published 2025-01-01“…The new reference genome will contribute to identifying stress resistance traits in pomegranates thriving in arid environments as well as new dietary antioxidants and antimicrobial peptides with pharmaceutical and therapeutic applications.…”
Get full text
Article -
953
Changes in the Intestinal Microbiota in Patients with Chronic Pancreatitis: Systematizing Literature Data
Published 2022-12-01“…The severe CP is associated with impaired synthesis of antimicrobial peptides, bicarbonates, and digestive enzymes by the pancreas, which is a risk factor for dysbiotic changes in the intestinal microbiota, consisting in the development of small intestinal bacterial overgrowth (SIBO) and gut dysbiosis. …”
Get full text
Article -
954
Injectable hyaluronic acid-based hydrogel niches to create localized and time-controlled therapy delivery
Published 2025-04-01“…We designed a system based on hyaluronic acid, crosslinked via click-reaction with multi-arm polyethyleneglycol and functionalized with RGD peptides. Additionally, we incorporated thiol-modified heparin into the formulation, which provides specific binding sites for cytokines. …”
Get full text
Article -
955
An HLA-Transgenic Mouse Model of Type 1 Diabetes That Incorporates the Reduced but Not Abolished Thymic Insulin Expression Seen in Patients
Published 2016-01-01“…Immune cell populations are not grossly altered, and the mice exhibit typical signs of islet autoimmunity, including CD8 T cell responses to beta cell peptides also targeted in HLA-A∗02:01-positive type 1 diabetes patients. …”
Get full text
Article -
956
Lipoxins and Annexin-1: Resolution of Inflammation and Regulation of Phagocytosis of Apoptotic Cells
Published 2006-01-01“…ALXR, originally identified as a low-affinity N-formyl-methionyl-leucyl-phenylalanine receptor-like 1, can bind pleiotropic ligands, i.e., both lipid and peptides, including the glucocorticoid-inducible protein, annexin-1. …”
Get full text
Article -
957
Direct detection and identification of viruses in saliva using a SpecID ionization modified mass spectrometer.
Published 2025-01-01“…Saliva testing has slowly gained popularity in the diagnostics based on biomarkers and other constituents ranging from organic compounds (e.g., food additives), peptides, and even microorganisms. Polymerase chain reaction (PCR) remains the gold standard for sensitive detection of SARS-CoV-2 infection in biological samples. …”
Get full text
Article -
958
Role of Opioid Ligands in the Irritable Bowel Syndrome
Published 1999-01-01“…Endogenous opioid peptides – enkephalins, beta-endorphin and dynorphins – are located in specific sites of the brain, the spinal cord, the autonomic ganglia and the enteric nervous system. …”
Get full text
Article -
959
Epitope-imprinted biomaterials with tailor-made molecular targeting for biomedical applications
Published 2025-03-01“…Additionally, we discuss the application of epitope-imprinted materials in the recognition and detection of peptides, proteins, and cells. Despite these advancements, challenges such as template complexity, imprinting efficiency, and scalability remain. …”
Get full text
Article -
960
Chronic Kidney Disease, Obesity, and Hypertension: The Role of Leptin and Adiponectin
Published 2012-01-01“…Remarkable improvements have been recently achieved in the study of the endocrine features of the adipose tissue and have been able to produce hormone-like peptides named adipokines or adipocytokines. Among these adipocytokines, which represent a link between obesity, hypertension, and chronic nephropathy, leptins and adiponectin appear to play an important role. …”
Get full text
Article