The Impact of Polyethylene Glycol-Modified Chitosan Scaffolds on the Proliferation and Differentiation of Osteoblasts by Wei-Bor Tsai, Ibrahim Nasser Ahmed

“…The chitosan polymer was initially modified by the predetermined concentration of the photoreactive azido group for UV-crosslinking and with RGD peptides (N-acetyl-GRGDSPGYG-amide). The PEG was mixed at different ratios (0, 10, and 20 wt%) with modified chitosan in 96-well tissue culture polystyrene plates to prepare CHI-100, CHI-90, and CHI-80 scaffolds. …”
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Anti-CCP: History and its Usefulness by M. Herold, V. Boeser, E. Russe, W. Klotz

“…Antibodies directed to cyclic citrullinated peptides (anti-CCP) are highly specific for rheumatoid arthritis (RA) and can easily be detected in sera by using commercially available immunoassays. …”
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Biological Synthesis of Silver Nanoparticles by Cell-Free Extract of Spirulina platensis by Gaurav Sharma, Nakuleshwar Dut Jasuja, Manoj Kumar, Mohammad Irfan Ali

“…FTIR and UV-Vis spectra showed that biomolecules, proteins and peptides, are mainly responsible for the formation and stabilisation of AgNPs. …”
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Upper Gastrointestinal Bleeding from Gastric Amyloidosis in a Patient with Smoldering Multiple Myeloma by Mihajlo Gjeorgjievski, Treta Purohit, Mitual B. Amin, Paul J. Kurtin, Mitchell S. Cappell

“…Liquid chromatography tandem mass spectrometry performed on peptides extracted from Congo red-positive microdissected areas of paraffin-embedded stomach specimens revealed a peptide profile consistent with AL- (lambda-) type amyloidosis. …”
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Spectroscopically Well-Characterized RGD Optical Probe as a Prerequisite for Lifetime-Gated Tumor Imaging by Julia Eva Mathejczyk, Jutta Pauli, Christian Dullin, Joanna Napp, Lutz-F. Tietze, Horst Kessler, Ute Resch-Genger, Frauke Alves

“…Labeling of RGD peptides with near-infrared fluorophores yields optical probes for noninvasive imaging of tumors overexpressing α v β 3 integrins. …”
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Antifibrotic Activity of Acylated and Unacylated Ghrelin by Elia Angelino, Simone Reano, Michele Ferrara, Emanuela Agosti, Andrea Graziani, Nicoletta Filigheddu

“…Although unacylated ghrelin does not bind or activate GHSR-1a, it shares with the acylated form several biological activities. Ghrelin peptides exhibit anti-inflammatory, antioxidative, and antiapoptotic activities, suggesting that they might represent an efficient approach to prevent or reduce fibrosis. …”
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Far beyond Phagocytosis: Phagocyte-Derived Extracellular Traps Act Efficiently against Protozoan Parasites In Vitro and In Vivo by Liliana M. R. Silva, Tamara Muñoz-Caro, Rafael A. Burgos, Maria A. Hidalgo, Anja Taubert, Carlos Hermosilla

“…Released ETs consist of nuclear DNA as backbone adorned with histones, antimicrobial peptides, and phagocyte-specific granular enzymes thereby producing a sticky extracellular matrix capable of entrapping and killing pathogens. …”
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Protein Glycation in Diabetes as Determined by Mass Spectrometry by Annunziata Lapolla, Laura Molin, Pietro Traldi

“…Enzymatic degradation products of in vitro glycated HSA were studied in order to simulate the in vivo enzymatic digestion of glycated species by the immunological system leading to the highly reactive advanced glycation end-products (AGEs) peptides. Further studies led to the evaluation of glycated Apo A-I and glycated haemoglobin levels. …”
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Effectiveness of the tetrapeptide HAEE: an innovative approach to Alzheimer's treatment in experimentation by Evgenii A. Patrakhanov

“…At the baseline (point 0), peptides and drugs were administered to two groups of animals aged 6 months. …”
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Arabidopsis conditional photosynthesis mutants abc1k1 and var2 accumulate partially processed thylakoid preproteins and are defective in chloroplast biogenesis by Joy Collombat, Manfredo Quadroni, Véronique Douet, Rosa Pipitone, Fiamma Longoni, Felix Kessler

“…They are synthesized in the cytoplasm with cleavable targeting sequences and the lumenal ones have bi-partite targeting sequences (first for the chloroplast envelope, second for the thylakoid membrane). Cleavage of these peptides is required to establish photosynthesis and a critical step of chloroplast biogenesis. …”
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Unveiling Cathepsin B inhibition with repurposed drugs for anticancer and anti-Alzheimer's drug discovery. by Mohammed Alrouji, Sabina Yasmin, Mohammed S Alshammari, Fahad A Alhumaydhi, Sharaf E Sharaf, Moyad Shahwan, Anas Shamsi

“…Alzheimer's disease (AD) is characterized by the aggregation of amyloid β (Aβ) peptides and the formation of plaques in the brain, primarily derived from the proteolytic degradation of amyloid precursor protein (APP). …”
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Current State of Type 1 Diabetes Immunotherapy: Incremental Advances, Huge Leaps, or More of the Same? by Brett Phillips, Massimo Trucco, Nick Giannoukakis

“…Other approaches have included intact putative autoantigens or autoantigen peptides. Considerable logistical outlays have been deployed to develop and to translate humanised antibodies targeting immune cells, cytokines, and cytokine receptors to the clinic. …”
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Trichosanthes dioica Roxb.: A vegetable with diverse pharmacological properties by Mahia Khandaker, Saleha Akter, Mohammad Zafar Imam

“…Different types of bioactive compounds have been identified and isolated from T. dioica including peptides namely trichosanthin and lectin; a number of triterpenes like cucurbitacin B, euphol, α-amyrin, β-amyrin, lupeol, taraxerol, betulin, and karounidiol; sterols, steroidal saponin, tannin, flavonoids etc. …”
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Harnessing the power of seaweed: unveiling the potential of marine algae in drug discovery by Leonel Pereira, Ana Valado

“…This review explores the emerging field of seaweed-based drug discovery and highlights the diverse range of bioactive compounds found in seaweeds, including polysaccharides, phlorotannins, pigments, and peptides. These compounds exhibit various pharmacological activities such as antioxidant, anti-inflammatory, antimicrobial, antiviral, and anticancer effects. …”
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Study of Traditional Uses, Extraction Procedures, Phytochemical Constituents, and Pharmacological Properties of Tiliacora triandra by Gitishree Das, Sushanto Gouda, Rout George Kerry, Hernán Cortes, María L. Del Prado-Audelo, Gerardo Leyva-Gómez, Patrick Valere Tsouh Fokou, Erick P. Gutiérrez-Grijalva, J. Basilio Heredia, Han-Seung Shin, Jayanta Kumar Patra

“…Bioactive compounds contained in T. triandra include phenolic compounds, alkaloids, flavonoids, terpenoids, fatty acids, essential amino acids, peptides, carbohydrates, vitamins, and nucleic acid precursors. …”
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Complete genome of mangrove-derived anti-MRSA streptomycete, Streptomyces pluripotens MUSC 135T by Hooi-Leng Ser, Kok-Gan Chan, Wen-Si Tan, Wai-Fong Yin, Bey-Hing Goh, Nurul-Syakima Ab Mutalib, Learn-Han Lee

“…Using bacteriocin mining tool, BAGEL detected eights gene clusters associated with bacteriocin production including lanthipeptides and linear azol(in)e-containing peptides (LAPs). Members of Streptomyces have contributed greatly towards improving lives, particularly against deadly infections and chronic diseases. …”
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Methodological considerations and implications for appetite and feeding behaviour research in PKU; Current knowledge, practical application and future perspectives by Ben Green

“…Regulated through homeostatic and non-homeostatic influences, appetite-related peptides and external cues existing in the physical environment work synergistically to maintain energy homeostasis. …”
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Transmission Electron Microscopic Morphological Study and Flow Cytometric Viability Assessment of Acinetobacter baumannii Susceptible to Musca domestica cecropin by Shuiqing Gui, Rongjiang Li, Yongwen Feng, Sanming Wang

“…Expectations about antimicrobial peptides' use as new powerful antibacterial agents have been raised on the basis of their unique mechanism of action. …”
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Antimicrobial proteins from oyster hemolymph improve the efficacy of conventional antibiotics. by Kate Summer, Qi Guo, Lei Liu, Bronwyn Barkla, Sarah Giles, Kirsten Benkendorff

“…Antimicrobial proteins and peptides (AMPPs) are considered among the most promising antibiotic alternatives and complementary therapies. …”
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Nose to brain strategy coupled to nano vesicular system for natural products delivery: Focus on synaptic plasticity in Alzheimer's disease by Nunzia Maisto, Dalila Mango

“…However, several compounds, administered parenterally and orally, are unable to reach the brain due to the presence of the blood-brain barrier (BBB) which prevents the passage of external substances, such as proteins, peptides, or phytocompounds, representing a limit to the development of treatment for neurodegenerative diseases, such as AD. …”
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