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841
Antimicrobial Properties of α-MSH and Related Synthetic Melanocortins
Published 2006-01-01“…The natural antimicrobial peptides are ancient host defense effector molecules, present in organisms across the evolutionary spectrum. …”
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842
Antioxidant and Chelating Activity of Nontoxic Jatropha curcas L. Protein Hydrolysates Produced by In Vitro Digestion Using Pepsin and Pancreatin
Published 2015-01-01“…These fractions were characterized by a large presence of peptides with different molecular masses. The hydrolysates exhibited both Cu2+ and Fe2+ chelating activity. …”
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843
Enzymatic Hydrolysis Systems Enhance the Efficiency and Biological Properties of Hydrolysates from Frozen Fish Processing Co-Products
Published 2024-12-01“…This study highlights the value of fish co-products as sources of functional peptides, contributing to waste reduction, and their potential applications in food, agriculture, and nutraceuticals.…”
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844
Neurobiology of Major Depressive Disorder
Published 2013-01-01“…Clinically, descriptive gene and protein expression analysis and genetic and functional studies revised here show that individual alterations of a complex signaling network, which includes the hypothalamic-pituitary-adrenal axis; the production of neurotrophins and growth factors; the expression of miRNAs; the production of proinflammatory cytokines; and, even, the abnormal delivery of gastrointestinal signaling peptides, are able to induce major mood alterations. …”
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845
Immunotherapeutic Strategies for Alzheimer's Disease Treatment
Published 2009-01-01“…Active and/or passive immunization against the amyloid-β peptide has been proposed as a method for preventing and/or treating AD. …”
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846
Cytokines and Liver Diseases
Published 2001-01-01“…Cytokines are pleiotropic peptides produced by virtually every nucleated cell in the body. …”
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847
Exploring covalent inhibitors of SARS-CoV-2 main protease: from peptidomimetics to novel scaffolds
Published 2025-12-01“…Peptidomimetic inhibitors mimic natural peptide substrates, employing electrophilic warheads to covalently interact with the catalytic Cys145 of Mpro. …”
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848
The Use of N-Terminal-Pro-BNP in Preterm Infants
Published 2009-01-01“…The use of natriuretic peptides in the neonatal population is emerging. B-type Natriuretic Peptide (BNP) and N-terminal-Pro-BNP (NTpBNP) are used in the adult population to assess myocardial function and volume loading. …”
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849
Development of Class IIa Bacteriocins as Therapeutic Agents
Published 2012-01-01“…Class IIa bacteriocins have been primarily explored as natural food preservatives, but there is much interest in exploring the application of these peptides as therapeutic antimicrobial agents. Bacteriocins of this class possess antimicrobial activity against several important human pathogens. …”
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850
Small Bowel Review: Part II
Published 1996-01-01“…Topics discussed are enterocyte proliferation and growth factors; amino acids, peptides and allergies; motility; salt and water absorption and secretion – diarrhea; vitamins and minerals; early development and ageing of the intestine; and ethanol effects.…”
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851
The Role of the Estimated Plasma Volume Variation in Assessing Decongestion in Patients with Acute Decompensated Heart Failure
Published 2025-01-01“…Conclusions: Indirect estimation of plasma volume and its variation are valuable, accessible, and cost-effective parameters for assessing decongestive treatment in ADHF patients, complementing natriuretic peptides.…”
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852
Biological evaluation and interaction mechanism of beta-site APP cleaving enzyme 1 inhibitory pentapeptide from egg albumin
Published 2020-06-01“…Then, molecular docking and molecular dynamics simulation were used to explain the molecular mechanism of the interactions between BACE1 and peptides. The IC50 value of peptide KLPGF, with satisfactory ADMET properties, against BACE1 was (8.30 ± 0.56) mmol/L. …”
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853
A Review on Factors Influencing the Fermentation Process of Teff (Eragrostis teff) and Other Cereal-Based Ethiopian Injera
Published 2022-01-01“…Biogenic amines, bioactive peptides, antinutrient reduction, and polyphenol conversion to physiologically active chemicals are all possible health benefits of fermentation process products. …”
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854
Radioimmunotherapy: A Specific Treatment Protocol for Cancer by Cytotoxic Radioisotopes Conjugated to Antibodies
Published 2014-01-01“…Radioimmunotherapy (RIT) represents a selective internal radiation therapy, that is, the use of radionuclides conjugated to tumor-directed monoclonal antibodies (including those fragments) or peptides. In a clinical field, two successful examples of this treatment protocol are currently extended by 90Y-ibritumomab tiuxetan (Zevalin) and 131I-tositumomab (Bexxar), both of which are anti-CD20 monoclonal antibodies coupled to cytotoxic radioisotopes and are approved for the treatment of non-Hodgkin lymphoma patients. …”
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855
Protein carbamylation and proteomics: from artifacts to elucidation of biological functions
Published 2025-01-01“…In addition, anti-acetyllysine antibodies co-purify carbamylated and acetylated peptides. In a recent paper, we leveraged co-purification with anti-acetyllysine antibodies to develop a method for analyzing carbamylated proteomes. …”
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856
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857
High-throughput Identification of Phage-derived Imaging Agents
Published 2006-01-01“…The use of phage-displayed peptide libraries is a powerful method for selecting peptides with desired binding properties. …”
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858
Signal and modulating role of enzymes of digestive glands
Published 2011-03-01“…Proteinases realize effects through protease-activated receptors of four types which are localized on membranes of glandular cells, leiomyocytes, sensory terminals of afferent neurons and neuroendocrine producers of regulatory peptides, yielding direct and mediated morphofunctional effects.Conclusion. …”
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859
Tribute to Roger Guillemin, a pioneer in neuroendocrinology (1924–2024), Nobel Prize in Physiology or Medicine
Published 2024-08-01“…He consequently demonstrated that these brain peptides regulate a large number of major body activities through neuroendocrine mechanisms. …”
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860
Convergence of Synapses, Endosomes, and Prions in the Biology of Neurodegenerative Diseases
Published 2013-01-01“…However, it is not thought that the prion-like quality of these proteins/peptides that allows their cell-to-cell transmission implies a role for human-to-human spread in common age-related neurodegenerative diseases. …”
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