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Purification and identification of anti-inflammatory peptides from sturgeon (Acipenser schrenckii) cartilage
Published 2023-11-01“…The current study aimed to investigate the potential anti-inflammatory activity of peptides derived from sturgeon (Acipenser schrenckii) cartilage in lipopolysaccharide (LPS)-stimulated RAW264.7 macrophages. Five peptide sequences, including four novel peptides, were identified from ethanol-soluble cartilage hydrolysates. …”
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Research Progress on Enzymatic Preparation and Functional Properties of Bioactive Peptides in Hairtail
Published 2025-02-01“…However, research on the specific peptide sequences responsible for bioactivity and their underlying mechanisms remains limited. …”
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23
AVP-GPT2: A Transformer-Powered Platform for De Novo Generation, Screening, and Explanation of Antiviral Peptides
Published 2024-12-01“…Trained on a significantly expanded dataset, AVP-GPT2 employs a transformer-based architecture to generate diverse peptide sequences. A multi-modal screening approach, incorporating Star-Transformer and Vision Transformer, enables accurate prediction of antiviral activity and toxicity, leading to the identification of potent and safe candidates. …”
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Synthetic Peptides as Potential Antigens for Cutaneous Leishmaniosis Diagnosis
Published 2017-01-01“…The research on the similarity of the peptides’ sequences in protein databases showed that they match a 63 kDa glycoprotein. …”
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25
UniAMP: enhancing AMP prediction using deep neural networks with inferred information of peptides
Published 2025-01-01“…Subsequently, we analyze the relations among peptide sequences, manually extracted features, and automatically inferred information by deep learning models, leading to observations that the inferred information is more comprehensive and non-redundant for the task of predicting AMPs. …”
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Applying the Concept of Peptide Uniqueness to Anti-Polio Vaccination
Published 2015-01-01“…Sequence analyses produced a set of consensus epitopic peptides potentially able to generate specific anti-polio immune responses exempt from cross-reactivity with the human host. Conclusion. Peptide sequences unique to poliovirus proteins and conserved among polio strains might help formulate a specific and universal anti-polio vaccine able to react with multiple viral strains and exempt from the burden of possible cross-reactions with human proteins. …”
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Production of antihypertensive and antidiabetic peptide fractions from quinoa (Chenopodium quinoa Willd.) by electrodialysis with ultrafiltration membranes
Published 2022-11-01“…Nevertheless, further characterization is needed towards peptide sequencing, their respective role in the metabolism and scaling-up production using EDUF.…”
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Kinetics of Mushroom Tyrosinase and Melanogenesis Inhibition by N-Acetyl-pentapeptides
Published 2014-01-01“…We investigated the kinetics of 4N-acetyl-pentapeptides, Ac-P1, Ac-P2, Ac-P3, and Ac-P4, regarding inhibition of mushroom tyrosinase activity. The peptides sequences of Ac-P1, Ac-P2, Ac-P3, and Ac-P4 were Ac-RSRFK, Ac-KSRFR, Ac-KSSFR, and Ac-RSRFS, respectively. …”
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Small peptides from non-edible fish waste with antimicrobial activity
Published 2025-01-01“…The result revealed that 11.15 mg/mL of hydrophobic peptide hydrolysate from intestines in pH during 3-10and 11.94 mg/mL of hydrophobic peptide hydrolysate from gill in pH 8-10 were able to inhibit the bacterial growths. 8 Peptide sequences from LCMS/MS were synthesized [GGLGVGGY; GLSGWAS; GAQEGSY; ALMAISL; LYMGLAVPL; VILLVAPAS; GGQSTDY; AFSGVEA]. …”
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Accelerating antimicrobial peptide design: Leveraging deep learning for rapid discovery.
Published 2024-01-01“…The investigation assesses 1,360 peptide sequences that exhibit anti- E. coli activity. …”
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31
Antimicrobial Peptides from Porcine Blood Cruor Hydrolysates as a Promising Source of Antifungal Activity
Published 2024-12-01“…To this end, a total of sixteen peptides were chemically synthesized and their antimicrobial activities (antibacterial, anti-mold, and anti-yeast) were evaluated using microtitration and agar well diffusion methods against a wide range of microorganisms. Five new peptide sequences demonstrated antifungal activity, with Pep5 (FQKVVAGVANALAHKYH), an alpha-helix peptide, exhibiting the most promising results. …”
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Advancing the accuracy of tyrosinase inhibitory peptides prediction via a multiview feature fusion strategy
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Molecular Assessment of Domain I of Apical Membrane Antigen I Gene in Plasmodium falciparum: Implications in Plasmodium Invasion, Taxonomy, Vaccine Development, and Drug Discovery
Published 2022-01-01“…The conserved short peptide sequences found in Domain I of Plasmodium falciparum apical membrane antigen 1 (PfAMA1), which are exposed on the parasite cell surface and in charge of Plasmodium falciparum invasion of host cells, make PfAMA1 a promising vaccine candidate antigen. …”
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Identification of a Novel Anticancer Oligopeptide from Perilla frutescens (L.) Britt. and Its Enhanced Anticancer Effect by Targeted Nanoparticles In Vitro
Published 2018-01-01“…The structure of the oligopeptide was determined using a peptide sequencer, and its anticancer effect was examined by the MTT assay. …”
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Isolation and identification of novel casein-derived bioactive peptides and potential functions in fermented casein with Lactobacillus helveticus
Published 2019-06-01“…Intracellular peptides are much larger in quantity and more complex in composition than extracellular peptides, between which the correlation reveals proteolytic and metabolic mechanisms.In addition, totally 241 different peptide sequences were identified by Nano LC–MS/MS from casein (212) and Lactobacillus helveticus proteins (29). …”
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