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1461
Proteomic Identification and Functional Analysis of Babesia microti Reveals Heparin-Binding Proteins
Published 2025-01-01“…Further studies were carried out to analyze those specific proteins with unique peptide segments of two or more, yielding 15 B. microti proteins, most of which are cell surface proteins and secretory proteins. …”
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1462
Efficacy and safety of once-weekly semaglutide monotherapy in a young subject with Prader-Willi syndrome, obesity, and type 2 diabetes: a case report
Published 2025-02-01“…BackgroundThe treatment of obesity and type 2 diabetes (T2D) in Prader-Willi syndrome (PWS) is still a challenge. Glucagon-like peptide 1 receptor agonists (GLP-1 RA) are attractive options, since they effectively reduce weight and improve blood glucose, without increasing the risk of hypoglycemia. …”
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1463
Reconstruction of Alzheimer’s Disease Cell Model In Vitro via Extracted Peripheral Blood Molecular Cells from a Sporadic Patient
Published 2020-01-01“…In conclusion, this study has successfully generated an AD cell model with pathological features of beta-amyloid peptide deposition using PBMC from a patient with sAD.…”
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1464
2′-O-Methylperlatolic Acid Enhances Insulin-Regulated Blood Glucose-Lowering Effect through Insulin Receptor Signaling Pathway
Published 2022-01-01“…Mice were injected with 2-O-M or normal saline and the average blood glucose concentration after 120 min, and the serum levels of insulin, glucagon, and C-peptide were measured. Next, qRT-PCR was performed to detect the mRNA expression of genes involved in lipid and glucose metabolism in the liver and muscle tissues. …”
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1465
Negative Association of Gulf War Illness Symptomatology with Predicted Binding Affinity of Anthrax Vaccine Antigen to Human Leukocyte (HLA) Class II Molecules
Published 2025-01-01“…Since the binding of a peptide to an HLA-II molecule is the first and necessary step in initiating the production of antibodies, the findings above support our hypothesis that the severity of GWI symptomatology is partly due to a lack of HLA-II protection. …”
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1466
Acupuncture and Kinesitherapy Improve Physical Activity More than Kinesitherapy Alone in Patients with Acute Decompensated Chronic Heart Failure with Reduced Ejection Fraction Who...
Published 2025-01-01“…Improvement in physical activity was measured by the modified Barthel index (A test), 2 or 6 min walking tests, an endurance walking test, and decrease of blood brain natriuretic peptide (BNP). <b>Results</b>: A total of 120 patients completed the study. …”
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1467
A simple staging system using biomarkers for wild‐type transthyretin amyloid cardiomyopathy in Japan
Published 2022-06-01“…We examined and validated the staging system using hs‐cTnT, eGFR, and B‐type natriuretic peptide (BNP) in Japanese patients with ATTRwt‐CM. …”
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1468
Biochemistry : the molecular basis of life /
Published 2017Table of Contents: “…Machine generated contents note: -- Table of Contents -- Chapter 1 Biochemistry: An Introduction -- Chapter 2 Living Cells -- Chapter 3 Water: The Matrix of Life -- Chapter 4 Energy -- Chapter 5 Amino Acids, Peptides, and Proteins -- Chapter 6 Enzymes -- Chapter 7 Carbohydrates -- Chapter 8 Carbohydrate Metabolism -- Chapter 9 Aerobic Metabolism I: The Citric Acid Cycle -- Chapter 10 Aerobic Metabolism II: Electron Transport and Oxidative Phosporylation -- Chapter 11 Lipids and Membranes -- Chapter 12 Lipid Metabolism -- Chapter 13 Photosynthesis -- Chapter 14 Nitrogen Metabolism I: Synthesis -- Chapter 15 Nitrogen Metabolism I: Degradation -- Chapter 16 Integration of Metabolism -- Chapter 17 Nucleic Acids -- Chapter 18 Genetic Information -- Chapter 19 Protein Synthesis.…”
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1469
Biochemistry : the molecular basis of life /
Published 2017Table of Contents: “…Machine generated contents note: -- Table of Contents -- Chapter 1 Biochemistry: An Introduction -- Chapter 2 Living Cells -- Chapter 3 Water: The Matrix of Life -- Chapter 4 Energy -- Chapter 5 Amino Acids, Peptides, and Proteins -- Chapter 6 Enzymes -- Chapter 7 Carbohydrates -- Chapter 8 Carbohydrate Metabolism -- Chapter 9 Aerobic Metabolism I: The Citric Acid Cycle -- Chapter 10 Aerobic Metabolism II: Electron Transport and Oxidative Phosporylation -- Chapter 11 Lipids and Membranes -- Chapter 12 Lipid Metabolism -- Chapter 13 Photosynthesis -- Chapter 14 Nitrogen Metabolism I: Synthesis -- Chapter 15 Nitrogen Metabolism I: Degradation -- Chapter 16 Integration of Metabolism -- Chapter 17 Nucleic Acids -- Chapter 18 Genetic Information -- Chapter 19 Protein Synthesis.…”
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1470
Photodynamic and photothermal bacteria targeting nanosystems for synergistically combating bacteria and biofilms
Published 2025-01-01“…In this current study, we have used chlorin e6 (Ce6), zeolitic imidazolate framework-8 (ZIF-8), polydopamine (PDA), and UBI peptide to formulate an innovative nanosystem meticulously engineered to confront bacterial infections and effectually dismantle biofilm architectures through the concerted mechanism of photodynamic therapy (PDT)/photothermal therapy (PTT) therapies, including in-depth research, especially for oral bacteria and oral biofilm. …”
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1471
Study on gene expression in the liver at various developmental stages of human embryos
Published 2025-01-01“…Concurrently, numerous genes related to vitamin response, brown adipocyte differentiation, T cell differentiation, hormone secretion, hemostasis, peptide hormone response, steroid metabolism, and hematopoietic regulation exhibited increased expression aligned with liver development. …”
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1472
The impact of the novel starch-lipid complexes on the glucolipids metabolism, inflammation, and gut dysbiosis of type 2 diabetes mellitus rats
Published 2024-11-01“…According to a serial of biochemical analyses, we found that RS5 diets were strongly correlated with enhanced homeostatic model assessment for insulin secretion (HOMA-IS), high-density lipoprotein cholesterol (HDL-C), adiponectin (ADP), insulin action index (IAI), glucagon-like peptide-1 (GLP1), and short-chain fatty acids (SCFAs) in T2DM rats whilst negatively associated with the low-density lipoprotein (LDL-C) and inflammatory cytokines, showing the capabilities to ameliorate T2DM symptoms by regulation of glucolipid metabolism, gut metabolites, and inflammation. …”
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1473
Retinoprotective therapy of glaucoma
Published 2022-11-01“…</p> <p> <b>Keywords</b>: glaucoma, systemic blood pressure, peptide preparation, retinal ganglion cells, neuroprotection, retinoprotection. …”
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1474
ВЫДЕЛЕНИЕ, ХАРАКТЕРИСТИКА И ПЕРСПЕКТИВЫ ИСПОЛЬЗОВАНИЯ ПЕПТИДОВ МОЛОЗИВА КОРОВ
Published 2022-10-01“…Белковые фракции ферментативного гидролизата молозива коров исследовали на масс-спектрометре МАЛДИ-ТОФ, расшифровку проводили с помощью базы данных Mascot, опция Peptide Fingerprint («Matrix Science», США) с использованием базы данных Protein NCBI. …”
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1475
NMR Studies on the Structure of Yeast Sis1 and the Dynamics of Its Interaction with Ssa1-EEVD
Published 2024-12-01“…We employed NMR spectroscopy to investigate the structure and dynamics of the class B J domain protein (JDP) of <i>S. cerevisiae</i> (Sis1) complexed with an EEVD peptide of Ssa1. Our study is based on the extraordinary 70.5% residue assignment of the full-length (352 residues long) Sis1. …”
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1476
Angiopoietin-2 and D-dimer add prognostic information to clinical risk in pulmonary arterial hypertension
Published 2025-02-01“…We assessed treatment response with Reveal Lite 2 scores (all patients had N-terminal-pro-brain natriuretic peptide, 6-minute walk, and functional class assessment at both visits) and followed clinical outcomes for 3 years. …”
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1477
How do serum cytokine levels change in myocarditis and inflammatory dilated cardiomyopathy relative to healthy individuals? A protocol for a systematic review and meta-analysis
Published 2025-02-01“…Subgroup analysis will be stratified by age, sex, sample size, New York Heart Association scale, cardiac Troponin T, N-terminal prohormone of brain natriuretic peptide, C reactive protein, number of lymphocytes per mm2 in the endomyocardial biopsy.Ethics approval and dissemination This study does not require ethics approval. …”
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1478
Risk Factors and Changes of Peripheral NK and T Cells in Pulmonary Interstitial Fibrosis of Patients with Rheumatoid Arthritis
Published 2019-01-01“…Rheumatoid factor, anti-cyclic citrulline peptide antibody, erythrocyte sedimentation rate, immunoglobulin, and C-reactive protein were examined. …”
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1479
Safety and Efficacy in Mitral Regurgitation Management with the MitraClip<sup>®</sup> G4 System: Insights from a Single-Center Study
Published 2024-12-01“…Lower baseline N-terminal pro-brain natriuretic peptide (NT-proBNP) predicted achieving NYHA class I at 30 days (HR: 0.63, 95% CI: 0.41–0.95, <i>p</i> = 0.030), while lower European System for Cardiac Operative Risk Evaluation II (EuroSCORE II) and NT-proBNP predicted it at 1 year [(HR: 0.50, 95% CI: 0.28–0.89, <i>p</i> = 0.019), (HR: 0.67, 95% CI: 0.44–0.99, <i>p</i> = 0.049), respectively]. …”
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1480
Vasoreactive testing prevalence and characteristics in patients with idiopathic pulmonary arterial hypertension
Published 2025-01-01“…Patients with negative VRT demonstrated worse hemodynamics and exercise tolerance, higher N-terminal pro-brain-type natriuretic peptide (NT-proBNP) level, and right heart dilatation compared with VRT+. …”
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