Methionine-driven methylation modification overcomes plasmid-mediated high-level tigecycline resistance by Dan Fang, Tianqi Xu, Fulei Li, Yue Sun, Jingyi Sun, Yanqing Yin, Haijie Zhang, Zhiqiang Wang, Yuan Liu

“…Abstract Tigecycline is a last-resort antibiotic to treat complicated infections caused by multidrug-resistant pathogens, while the emergence of plasmid-mediated tet(X) family severely compromises its clinical efficacy. …”
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Biocontrol Potential of Rhizospheric Bacillus Strains Against <i>Sclerotinia minor</i> Jagger Causing Lettuce Drop by Lihui Xu, Qinghua Shang, Mogens Nicolaisen, Rong Zeng, Shigang Gao, Ping Gao, Zhiwei Song, Fuming Dai, Jingze Zhang

“…Bac20 inhibited oxalic acid formation in early-stage lettuce leaves infected with <i>S. minor</i> Jagger, delaying pathogen infestation. Greenhouse experiments for controlling lettuce drop demonstrated that inoculation with Bac20 controlled lettuce drop by 71.7%. …”
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Laboratory capacity-building during COVID-19 in Somalia: improving access to essential diagnostics for national health security in a fragile setting by Salvador Figuereo, Sahra Isse Mohamed, Desalegn Takele, Abdulrahman M. Sheikh, Solomon Chane Abera, Ayni Muhiadin Mohamed, Mutaawe Lubogo, Hassan Mukhtar Abukar, Mary Joan Karanja, Sulaiman Bangura, Antoine Abou Fayad, Ali Haji Adam, Abdinasir Yusuf Osman, Sk Md Mamunur Rahman Malik

“…We describe how the country moved rapidly from no testing capability to molecular testing and genomic sequencing for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and other pathogens. Methods We reviewed primary sources information as well as data and records from secondary sources from 1 January 2020 to 31 December 2023. …”
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homeRNA self-blood collection enables high-frequency temporal profiling of presymptomatic host immune kinetics to respiratory viral infection: a prospective cohort studyResearch in... by Fang Yun Lim, Hannah G. Lea, Ashley M. Dostie, Soo-Young Kim, Tammi L. van Neel, Grant W. Hassan, Meg G. Takezawa, Lea M. Starita, Karen N. Adams, Michael Boeckh, Joshua T. Schiffer, Ollivier Hyrien, Alpana Waghmare, Erwin Berthier, Ashleigh B. Theberge

“…In this nationwide prospective cohort study, we leveraged a Tasso-SST based self-blood collection and stabilization tool (homeRNA) to profile detailed kinetics of the presymptomatic to convalescence host immunity to contemporaneous respiratory pathogens. Methods: We enrolled non-symptomatic adults with recent exposure to ARIs who subsequently tested negative (exposed-uninfected) or positive for respiratory pathogens. …”
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Inflammasome in Intestinal Inflammation and Cancer by Tiago Nunes, Heitor S. de Souza

“…The activation of specific cytosolic pathogen recognition receptors, the nucleotide-binding-oligomerization-domain- (NOD-) like receptors (NLRs), leads to the assembly of the inflammasome, a multimeric complex platform that activates caspase-1. …”
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PRIMARY MENINGOENCEPHALITIS CAUSED BY NAEGLERIA FOWLERI: A MINI REVIEW by Hassan Bin-Asif et al

“…FLA other than N. fowleri such as Acanthamoeba and Balamuthia species are also harmful because they are vectors of many bacterial pathogens including Vibrio, Pseudomonas, Legionella, Enterobacter and Mycobacterium species which help them to feed and colonize in environments, thus contributing to their pathogenesis and transferability to their hosts. …”
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Infectious Keratitis: Secreted Bacterial Proteins That Mediate Corneal Damage by Mary E. Marquart, Richard J. O'Callaghan

“…Studies of these bacterial pathogens have determined the proteins of interest that could be targets for future therapeutic options for decreasing corneal damage.…”
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Phytophthora Identification and Sampling in Citrus Nurseries by Jamie D. Burrow, Diane B. Bright, Tim D. Riley, Evan G. Johnson, James H. Graham

“… Phytophthora species are important soilborne, fungus-like pathogens that attack the root systems, trunk, and fruit of citrus trees at any age. …”
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Discovery of a parallel family of euglenatide analogs in Euglena gracilis by Ahmed H. Elbanna, Xinhui Kou, Dilip V. Prajapati, Surasree Rakshit, Rebecca A. Butcher

“…These compounds have antiproliferative activity against fungal pathogens and mammalian cancer cell lines. Analysis of E. gracilis extracts revealed that the algae produce not only the euglenatides, but also a corresponding family of analogs that have the same molecular weights as the euglenatides, but are lacking the characteristic triene chromophore. …”
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Septic Systems and Springs Water Quality: An Overview for Florida by Mary Lusk, Andrea Albertin, Whitney Elmore, William Lester, James Moll

“… Wastewater carries pathogens, nutrients (nitrogen and phosphorus), and trace organic chemicals that may be harmful to human health and ecosystem functioning. …”
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Botryosphaeria Stem Blight on Southern Highbush Blueberry in Florida by Norma C. Flor, Douglas A. Phillips, Philip F. Harmon

“…Biotic or abiotic stresses from a variety of sources can make plants more susceptible to infection by stem blight pathogens. This new 5-page publication is intended for Florida blueberry growers to use as a guide in the identification and management of Botryosphaeria stem blight on southern highbush blueberry. …”
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Diarrhea in Farmed White-tailed Deer Fawns by Juan Manuel Campos Krauer, Samantha Wisely

“…Wisely and published by the UF/IFAS Department of Wildlife Ecology and Conservation focuses on disease in fawns caused by pathogenic types of Escherichia coli, describes the pathogens and how they infect fawns, and includes advice about treatment and prevention. https://edis.ifas.ufl.edu/uw463   …”
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Synthesis, Characterization, and Biotoxicity of NN⌢ Donor Sulphonamide Imine Silicon(IV) Complexes by Mukta Jain, R. V. Singh

“…In the search for better fungicides, bactericides, nematicides, and insecticides studies were conducted to assess the growth-inhibiting potential of the synthesized complexes against various pathogenic fungal, bacterial strains, root-knot nematode Meloidogyne incognita, and insect Trogoderma granarium These studies demonstrate that the concentrations reached levels which are sufficient to inhibit and kill the pathogens, nematode, and insect.…”
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Dual role of pyroptosis in liver diseases: mechanisms, implications, and therapeutic perspectives by Siyuan Yang, Yunyi Zou, Chunhua Zhong, Zuoqiong Zhou, Xiyang Peng, Changfa Tang

“…It facilitates the clearance of damaged hepatocytes, preventing secondary injury, and triggers immune responses to eliminate pathogens and damaged cells. Conversely, excessive pyroptosis intensifies inflammatory responses, exacerbates hepatocyte damage and promotes the activation and proliferation of hepatic stellate cells, accelerating liver fibrosis. …”
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Regulation of Dendritic Cell Function in Inflammation by André Said, Günther Weindl

“…During steady state immune surveillance in skin, DC act as sentinels against commensals and invading pathogens. Under pathological skin conditions, inflammatory cytokines, secreted by surrounding keratinocytes, dermal fibroblasts, and immune cells, influence the activation and maturation of different DC populations including Langerhans cells (LC) and dermal DC. …”
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Peptidoglycan and Bacterial DNA Induce Inflammation and Coagulation Markers in Synergy by Marie-Claude Amoureux, Nandani Rajapakse, Lazlo Stipkovits, Susan Szathmary

“…Bacterial compounds signal the presence of foreign pathogens in the innate immune system. These microbial components are key players in infectious diseases and implicate toll-like receptors in the activation of inflammation and coagulation. …”
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Sous Vide Cookery: Foodservice Application for Larger, Less Tender Cuts by Chad Carr, Derek Griffing, Kaylie Madore, Dwain Johnson, Jason Scheffler, João Neto

“… Meat with an abundance of connective tissue presents a certain challenge to cooks who want to make it more tender while still properly eliminating pathogens that cause foodborne illness. Sous vide cookery provides precise temperature control and tenderness improvement with minimal supervision throughout cooking as well as consistent, almost perfect reproducibility. …”
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Effects of isolation and slaughter strategies in different species on emerging zoonoses by Jing-An Cui, Fangyuan Chen

“…Zoonosis is the kind of infectious disease transmitting among different species by zoonotic pathogens. Different species play different roles in zoonoses. …”
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Phytophthora Identification and Sampling in Citrus Nurseries by Jamie D. Burrow, Diane B. Bright, Tim D. Riley, Evan G. Johnson, James H. Graham

“… Phytophthora species are important soilborne, fungus-like pathogens that attack the root systems, trunk, and fruit of citrus trees at any age. …”
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Therapeutic Drug Monitoring of Meropenem in Neonate with Necrotizing Enterocolitis: A Challenge by Steven De Keukeleire, Daniëlle Borrey, Wim Decaluwe, Marijke Reynders

“…Dosing strategy will achieve adequate patient outcome when treating pathogens with elevated MIC. As safe as meropenem is, there are not enough data for 40 mg/kg, every 8 h infused over 4 h; accordingly, strict monitoring of blood levels is mandatory. …”
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