Impact of frequent ARID1A mutations on protein stability provides insights into cancer pathogenesis by Rajen K. Goutam, Gangtong Huang, Exequiel Medina, Feng Ding, William J. Edenfield, Hugo Sanabria

“…This research paves the way for identifying and categorizing which ARID1A mutations are most pathogenic, potentially guiding the development of targeted therapies tailored to specific mutation profiles in cancer treatment.…”
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Use of real-time polymerase chain reaction for investigation of Senecavirus infection occurrence in Russia by M. V. Timanov, A. M. Timina, M. V. Biryuchenkova

“…This is the first report on Senecavirus detection in the Russian Federation. The threat of the pathogen introduction from other countries requires further Senecavirus infection investigation and control. …”
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Analysis of the low density lipoprotein receptor gene (<i>LDLR</i>) mutation spectrum in Russian familial hypercholesterolemia by V. B. Vasilyev, F. M. Zakharova, T. Yu. Bogoslovskaya, M. Yu. Mandelshtam

“…Other regions are poorly studied. The majority of pathogenic mutations (142 out of 203 reported here or 70 %) were revealed in single pedigrees; 61 variants of mutations were described in two or more genealogies; only 5 mutations were found in 10 or more families. …”
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Selected microwave irradiation effectively inactivates airborne avian influenza A(H5N1) virus by Pietro Bia, Margherita Losardo, Antonio Manna, Silvio Brusaferro, Gaetano P. Privitera, Alberto Sangiovanni Vincentelli

“…Abstract The highly pathogenic avian influenza A(H5N1) virus threatens animal and human health globally. …”
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Altering the redox status of Chlamydia trachomatis directly impacts its developmental cycle progression by Vandana Singh, Scot P Ouellette

“…Chlamydia trachomatis is an obligate intracellular bacterial pathogen with a unique developmental cycle. It differentiates between two functional and morphological forms: the elementary body (EB) and the reticulate body (RB). …”
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Comparative investigation of specific enzyme activities in the organs and tissues of the skin parasite Macrogyrodactylus congolensis (Monogenea: Gyrodactylidae) by Safaa Zaky Arafa, El-Sayed Kasem Abd El-Hady, Samir Ahmed El-Abbassy

“…Abstract Background Macrogyrodactylus congolensis is a pathogenic skin parasite that infects the economically important fish Clarias gariepinus. …”
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The Genetic Perspective of Familial Glucocorticoid Deficiency: In Silico Analysis of Two Novel Variants by Katayoun Heshmatzad, Nejat Mahdieh, Ali Rabbani, Abdolah Didban, Bahareh Rabbani

“…A comprehensive search was conducted to find the reported variants of MC2R and MRAP genes. In silico pathogenic analysis was performed for the reported variants. …”
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Review of non-Helicobacter pylori Helicobacter species: Insights into pathogenesis, epidemiology, and clinical implications by M. Kroiß, B. Teodorescu, T. Song, R. Vasapolli

“…Although there has been a significant improvement in the overall awareness regarding NHPH infections, it remains a challenge to identify new species and distinguish between low and high pathogenicity levels. Further research is needed to understand how NHPH impacts human health, with a focus on improved diagnostic tools and treatment strategies.…”
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In Vitro Antibacterial Activities of Methanolic Extracts of Fruits, Seeds, and Bark of Zanthoxylum armatum DC by Nirmala Phuyal, Pramod Kumar Jha, Pankaj Prasad Raturi, Sangeeta Rajbhandary

“…The fruits, seeds, and bark extracts of Z. armatum exhibited remarkable antibacterial properties against different pathogenic bacteria causing several diseases, which suggests the potential use of this plant for treating different bacterial diseases such as skin infection, urinary tract infection, dental problems, diarrhea, and dysentery.…”
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Transcription factor TCF4: structure, function, and associated diseases by R. R. Savchenko, N. A. Skryabin

“…This review focuses on the TCF4 gene that encodes a transcription factor crucial for nervous system development and functioning. Pathogenic variants in this gene have been linked to a rare genetic disorder, Pitt–Hopkins syndrome, and TCF4 polymorphic variants are associated with several socially significant diseases, including various psychiatric disorders. …”
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Severe Pulmonary Infection in a 20-Month-Old Female by Yasmeen Mann, Paul Zeller, Kristen Carrillo-Kappus, Melissa Victor, Mary Moore

“…Seven days after second VATS, a respiratory pathogen panel was positive for rhinovirus/enterovirus. …”
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Identification of G-quadruplex-forming Sequences in Nucleocapsid Gene of SARS-CoV-2 Variants of Concern: An In Silico Analysis by Saeedeh Ghazaey Zidanloo

“…Therefore, due to the loss of this important PQS or indeed an obstacle to viral replication, the Delta variant could exhibit higher reproduction and pathogenicity than other variants of concern.…”
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Sustainable Nutritional Strategies for Gut Health in Weaned Pigs: The Role of Reduced Dietary Crude Protein, Organic Acids and Butyrate Production by Kathryn Ruth Connolly, Torres Sweeney, John V. O’Doherty

“…Reducing dietary crude protein mitigates the availability of undigested proteins for pathogenic bacteria, lowering harmful by-products like ammonia and branched-chain fatty acids, which exacerbate dysbiosis. …”
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The prevalence of multidrug resistance in Staphylococcus hominis isolated from clinical materials by Magdalena Szemraj, Paulina Glajzner, Kamila Olszowiec, Monika Sienkiewicz

“…Moreover, these bacteria can constitute a reservoir of resistance genes for more pathogenic bacteria.…”
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Unveiling the prenatal features of HADDS: A case report and literature review by Lina Hu, Dongzhi Li, Li Zhen, Yanan Wang

“…The variant is a de novo shifted code mutation, which expands the pathogenic gene spectrum of EBF3. Furthermore, we did a retrospective analysis of HADDS patients with a history of pregnancy and childbirth. …”
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Interesting Cytokine Profile Caused by Clinical Strains of Pseudomonas aeruginosa MDR Carrying the exoU Gene by Nallely S. Badillo-Larios, Edgar Alejandro Turrubiartes-Martínez, Esther Layseca-Espinosa, Roberto González-Amaro, Luis Fernando Pérez-González, Perla Niño-Moreno

“…Pseudomonas aeruginosa is an opportunistic pathogen in HAIs with two facets: the most studied is the high rate of antimicrobial resistance, and the less explored is the long list of virulence factors it possesses. …”
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Streptococcus constellatus Peritonitis and Subsequent Septic Shock following Intrauterine Device Removal by Joan Tymon-Rosario, Jessica M. Atrio, Hyun Ah Yoon, David Erlichman, Veronica Lerner

“…Streptococcus constellatus is a highly pathogenic organism once a systemic septic infection has become established that can cause an ascending genital tract infection resulting in tubo-ovarian abscess formation, peritonitis, and septic shock.…”
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Major Outer Membrane Protein from Legionella pneumophila Inhibits Phagocytosis but Enhances Chemotaxis of RAW 264.7 Macrophages by Regulating the FOXO1/Coronin-1 Axis by Zehui Yang, Yingying Chen, Qiang Zhang, Xiaodong Chen, Ze Deng

“…Legionella pneumophila is an intracellular pathogen that can cause Legionnaire’s disease by invading alveolar epithelial cells and macrophages. …”
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Unusual Findings of Human-Associated Four-Nucleated <i>Entamoeba</i> Species in Captive Wild Animals by Lorena Esteban-Sánchez, Juan José García-Rodríguez, Francisco Ponce-Gordo

“…Several species of amoebae in the genus <i>Entamoeba</i> forming four-nucleated mature cysts are pathogenic, but their identification is challenging due to a lack of distinctive morphological traits. …”
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Changing Landscape of Haemophilus influenzae Meningitis and Implication on Public Health by John Allonce, Mohammed Ahsan, Angelina Browne, Rebecca Witherell, Mark Rasnake

“…Haemophilus influenzae (H. influenzae) has evolved as a prominent pathogen, with nontypeable strains (NTHi) emerging as a leading cause of invasive disease, particularly among the elderly. …”
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