Neuroinflammation and ALS: Transcriptomic Insights into Molecular Disease Mechanisms and Therapeutic Targets by Giovanna Morello, Antonio Gianmaria Spampinato, Sebastiano Cavallaro

“…Despite the mechanism underlying motor neuron death is not yet clarified, multiple pathogenic processes have been proposed to account for ALS. …”
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Isolation, Identification, and Resistance Test of Escherichia coli to Antibiotics in Ujung Berung Broiler Poultry by Fatia Nasyna Afifa Kantamaryana, Roostita L Balia, Wendry Setiyadi Putranto

“…Escherichia coli is commensal bacteria in the intestinal of broiler chickens with low virulence. However, mostly pathogenic and cause colibacillosis illness. Inappropriate use of antibiotics in broiler chickens has been widely reported. …”
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Regulatory Role of CD4+ T Cells in Myocarditis by Daria Vdovenko, Urs Eriksson

“…In the presence of tissue damage and innate immune activation, however, activated self-antigen-loaded dendritic cells promote CD4+ effector T cell expansion and myocarditis. So far, a direct pathogenic role has been described for both activated Th17 and Th1 effector CD4+ T cell subsets, though Th1 effector T cell-derived interferon-gamma was shown to limit myocarditis severity and prevent transition to inflammatory dilated cardiomyopathy. …”
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Identifying Safeguards Disabled by Epstein-Barr Virus Infections in Genomes From Patients With Breast Cancer: Chromosomal Bioinformatics Analysis by Bernard Friedenson

“…Breakpoint distributions in breast and EBV-associated cancers on some chromosomes were not confidently distinguished (P ConclusionsEBV infection predisposes one to breast cancer and metastasis, even if the virus disappears. Identifying this pathogenic viral damage may improve screening, treatment, and prevention. …”
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The Interplay Between Viral Infection and Cell Death: A Ping-Pong Effect by Alireza Nourazarian, Hadi Yousefi, Cigir Biray Avci, Behrouz Shademan, Emad Behboudi

“…This study emphasizes the importance of investigating the mechanisms by which viruses control the host’s PCD machinery to gain insight into the evolutionary dynamics of host-pathogen interactions and to develop new approaches for predicting and managing viral threats. …”
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Recent Advances in Drug-Induced Hypersensitivity Syndrome/Drug Reaction with Eosinophilia and Systemic Symptoms by Hideaki Watanabe

“…TNF-α and TARC levels also reflect therapeutic responses and may be useful markers of the DIHS disease process. Recently, the pathogenic mechanism of T-cell activation triggered by human leukocyte antigen- (HLA-) restricted presentation of a drug or metabolites was elucidated. …”
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Culturable Bacterial Communities Related to Different Larval Stages of Sanys irrosea (Guenee, 1852) (Lepidoptera: Noctuoidae) by Elif Sevim, Ali Sevim

“…In addition, some potential slug, human and plant pathogenic bacteria (Moraxella osloensis, Kocuria rosea and Clavibacter michi-ganensis) were isolated. …”
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PERBANDINGAN KEMAMPUAN EKSTRAK KULIT PISANG AGUNG SEMERU DAN PISANG MAS KIRANA VARIETAS LUMAJANG DALAM MENGHAMBAT PERTUMBUHAN Candida albicans by Dwi Nur Rikhmasari

“…The purpose of this research is to know the difference of banana extract of Agung Semeru and banana Mas Kirana varieties of lumajang, in inhibiting the growth of pathogenic fungi Candida albicans, and to know the optimal concentration which can inhibit the growth of Candida albicans. …”
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Dynamic collateral sensitivity profiles highlight opportunities and challenges for optimizing antibiotic treatments. by Jeff Maltas, Anh Huynh, Kevin B Wood

“…Here, we use laboratory evolution in the opportunistic pathogen Enterococcus faecalis to phenotypically characterize collateral profiles through evolutionary time. …”
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Post-COVID Mucormycosis: An Emerging Threat in Developing Countries - A Prospective Review by Debpratim Chakraborty, Sudipa Adhikary

“…The growth of the mucor pathogen requires free iron, which is elevated in conditions like diabetic ketoacidosis. …”
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The Role of TLR2, TLR4, and TLR9 in the Pathogenesis of Atherosclerosis by Mohsin H. K. Roshan, Amos Tambo, Nikolai P. Pace

“…They are expressed by a variety of immune cells where they recognize pathogen-associated molecular patterns (PAMPs). TLRs recruit adaptor molecules, including myeloid differentiation primary response protein (MYD88) and TIRF-related adaptor protein (TRAM), to mediate activation of MAPKs and NF-kappa B pathways. …”
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COVID-19: Lessons from the Past to Inform the Future of Healthcare by Camilla Mattiuzzi, Giuseppe Lippi

“…The key issues that hindered an effective response to coronavirus disease 2019 (COVID-19) are numerous and multifaceted, and some of these will be critically examined in this article, including delayed identification of the pathogen, inadequate public health preparedness, inadequate therapeutic management, and deficiencies in laboratory diagnostics. …”
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Contamination with escherichia coli of homemade fresh butter in rural areas of ferizaj and gjilan in kosovo by Enver Bajrami, Kapllan Sulaj

“…<p> <b> Conclusions:</b> Homemade fresh butter produced from fresh cows milk in rural areas of Kosovo is commonly contaminated with different kinds of microorganisms as well as by pathogenic strains of E. coli. The poor hygienic home conditions in some rural areas in Kosovo have impact in the butter quality and are associated with the increasing number of E. coli.…”
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It Is All in the Genes: A Story of Unexpected Survival in a 67-Year-Old Male with Metastatic Pancreatic Cancer by Patsy W. P. Lee, Scott W. Strum, Elena Tsvetkova

“…Genetic testing revealed a pathogenic heterozygous germline BRCA2 6643delT p.(Tyr2215Thrfs∗14) frameshift mutation and somatic GNAS 2531G>A p.…”
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Mechanisms of allorecognition and xenorecognition in transplantation by Il Hee Yun, Jaeseok Yang

“…Innate immune cells, such as dendritic cells, identify pathogen- or danger-associated molecular patterns through pattern recognition receptors, thereby facilitating effective antigen presentation to T cells. …”
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The chemistry of gut microbiome in health and diseases by Agnes Wei Yin Lau, Loh Teng-Hern Tan, Nurul-Syakima Ab Mutalib, Sunny Hei Wong, Vengadesh Letchumanan, Learn-Han Lee

“…The balance between protective and pathogenic microbes must be kept in check to prevent disease onset. …”
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Essential Oils as Natural Food Preservatives: Special Emphasis on Antimicrobial and Antioxidant Activities by Nooshin Noshirvani

“…EOs and their components have exhibited high antimicrobial properties toward different pathogenic and spoilage microorganisms containing Gram-negative and Gram-positive species, mycobacteria, yeasts, and molds. …”
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Chaperone Hsp70 helps Salmonella survive infection-relevant stress by reducing protein synthesis. by Carissa Chan, Eduardo A Groisman

“…We now report that the Hsp70 from the bacterial pathogen Salmonella enterica serovar Typhimurium-termed DnaK-independently reduces protein synthesis in vitro and in S. …”
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The Role of Combining Probiotics in Preventing and Controlling Inflammation: A Focus on the Anti-Inflammatory and Immunomodulatory Effects of Probiotics in an In Vitro Model of IBD by Shadi Aghamohammad, Amin Sepehr, Seyedeh Tina Miri, Saeideh Najafi, Mohammad R. Pourshafie, Mahdi Rohani

“…A quantitative real-time polymerase chain reaction (qPCR) assay was conducted to analyze the expression of JAK/STAT and inflammatory genes after treatment with the probiotic mixture before, after, and simultaneously with the sonicated pathogen in the HT-29 cell line. The production of IL-6 and IL-1β after probiotic treatment was investigated via cytokine assay. …”
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Bioconversion of Keratin Wastes Using Keratinolytic Microorganisms to Generate Value-Added Products by Muhammed Seid Anbesaw

“…Due to the introduction of this waste associated with different pathogenic organisms into soil and water bodies, human beings and other small and large animals are affected by different diseases. …”
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