An Exhaled Breath Sampler Based on Condensational Growth and Cyclone Centrifugation (BSCC) by Lebing Wang, Jianguo Deng, Dongbin Wang, Menghao Chen, Xue Li, Yun Lu, Jingkun Jiang

“…This enables rapid sample collection and eliminates certain pre-treatment steps for pathogenic microorganism analysis. Laboratory-generated aerosols were mixed with saturated water vapor to simulate exhaled breath, and the collection efficiency and the virus infectivity conservation efficiency of the BSCC were evaluated. …”
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A Novel Spontaneous Mutation of the SOX10 Gene Associated with Waardenburg Syndrome Type II by Sen Chen, Yuan Jin, Le Xie, Wen Xie, Kai Xu, Yue Qiu, Xue Bai, Hui-Min Zhang, Xiao-Zhou Liu, Xiao-Hui Wang, Wei-Jia Kong, Yu Sun

“…WS is classified into four types depending on the clinical phenotypes. Currently, pathogenic mutation of PAX3, MITF, EDNRB, EDN3, SNAI2, or SOX10 can cause corresponding types of WS. …”
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Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells by Jonathan Kevin Sia, Maria Georgieva, Jyothi Rengarajan

“…TB is caused by the human pathogen, Mycobacterium tuberculosis (Mtb), which infects primarily innate immune cells patrolling the lung. …”
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Synthesis, Spectroscopic Characterisation, and Biopotential and DNA Cleavage Applications of Mixed Ligand 4-N,N-Dimethylaminopyridine Metal Complexes by C. Surendra Dilip, K. Manikandan, D. Rajalaxmi (a) Subahashini, R. Thiruneelakandan

“…The antimicrobial studies against various pathogenic bacterial and fungal serums insist on that the enhanced potential of the complexes over their ligand and their biopotential properties increases with concentration. …”
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Coffea canephora Peptides in Combinatorial Treatment with Fluconazole: Antimicrobial Activity against Phytopathogenic Fungus by Gabriela C. V. Bard, Gabriel B. Taveira, Thaynã A. M. Souza, Érica O. Mello, Sávio B. Souza, Alessandro C. Ramos, André O. Carvalho, Lídia S. Pereira, Umberto Zottich, Rosana Rodrigues, Valdirene M. Gomes

“…The objective of the present study was to evaluate the antimicrobial activity of the Cc-LTP2 and Cc-GRP peptides isolated from Coffea canephora seeds and their possible synergistic activity with the azole drug fluconazole and characterize their mechanisms of action on cells of pathogenic fungi. Cc-LTP2 and Cc-GRP alone or in combination with 20 µg/mL of fluconazole were evaluated for their antimicrobial activity on the fungus Fusarium solani, and the effects of these peptides on the permeability of membranes and the induction of oxidative stress were determined. …”
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Role of Mitochondria-Associated Endoplasmic Reticulum Membrane in Inflammation-Mediated Metabolic Diseases by Themis Thoudam, Jae-Han Jeon, Chae-Myeong Ha, In-Kyu Lee

“…MAM provides an excellent platform for numerous signaling pathways; among them, inflammatory signaling pathways associated with MAM play a critical role in cellular defense during pathogenic infections and metabolic disorders. However, induction of MAM causes deleterious effects by amplifying mitochondrial reactive oxygen species generation through increased calcium transfer from the ER to mitochondria, thereby causing mitochondrial damage and release of mitochondrial components into the cytosol as damage-associated molecular patterns (DAMPs). …”
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Traffic Control of Bacteria-Derived Molecules: A New System of Host-Bacterial Crosstalk by Hiroaki Konishi, Mikihiro Fujiya, Yutaka Kohgo

“…Virulent microorganisms, such as pathogenic bacteria and viruses, are recognized by pattern recognition receptors (PRRs), including toll-like receptors (TLRs) and nucleotide-binding oligomerization-domain proteins (NODs), and induce inflammatory responses in mammalian hosts. …”
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Pisonia Alba Assisted Synthesis of Nanosilver for Wound Healing Activity by Suba Kannaiyan, D. Easwaramoorthi, Karthik Kannan, Andal Gopal, R. Lakshmipathy, Khadijah Mohammedsaleh Katubi, Nayef S. Almuaikel, Ivan Leandro Rodriguez Rico

“…Antibacterial and antibiofilm potential of synthesized silver nanoparticles against pathogenic organisms Gram-positive (Staphylococcus aureus) and Gram-negative (Escherichia coli) bacteria were investigated. …”
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Microbial Contamination of Nebulizers in Patients With Cystic Fibrosis by Cansu Yilmaz Yegit, Pinar Ergenekon, Nurcan Duman, Hakan Mursaloglu, Muruvvet Cenk, Burcu Suzer Uzunoglu, Gamze Tastan, Yasemin Gokdemir, Ela Erdem Eralp, Aysegul Karahasan Yagci, Fazilet Karakoc, Bulent Karadag

“…Conclusion: The nebulizer contamination rate with pathogenic microorganisms is low in the present study. …”
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Molecular Identification of Mycobacterium Species of Public Health and Veterinary Importance from Cattle in the South State of México by Adrian Zaragoza Bastida, Nallely Rivero Pérez, Benjamín Valladares Carranza, Keila Isaac-Olivé, Pablo Moreno Pérez, Horacio Sandoval Trujillo, Ninfa Ramírez Durán

“…Except M. parafortuitum, the other species identified are of public health and veterinary concern because they are pathogenic to humans, especially those with underlying medical conditions.…”
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Immunomodulatory Properties of HLA-G in Infectious Diseases by Laurence Amiot, Nicolas Vu, Michel Samson

“…In this review, we summarize the features of HLA-G expression by type of infections (i.e, bacterial, viral, or parasitic) detailing the state of knowledge for each pathogenic agent. The polymorphism, the interference of viral proteins with HLA-G intracellular trafficking, and various cytokines have been described to modulate HLA-G expression during infections. …”
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A thermodynamic bottleneck in the TCA cycle contributes to acetate overflow in Staphylococcus aureus by Nabia Shahreen, Jongsam Ahn, Adil Alsiyabi, Niaz Bahar Chowdhury, Dhananjay Shinde, Sujata S. Chaudhari, Kenneth W. Bayles, Vinai C. Thomas, Rajib Saha

“…Overall, our findings suggest that overflow metabolism offers S. aureus distinct bioenergetic advantages over a thermodynamically constrained TCA cycle, potentially supporting its commensal–pathogenic lifestyle.…”
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Current Advance and Future Prospects of Tissue Engineering Approach to Dentin/Pulp Regenerative Therapy by Ting Gong, Boon Chin Heng, Edward Chin Man Lo, Chengfei Zhang

“…Apart from the potential health risks of immunological rejection and pathogenic transmission, the lack of a well-established banking system for the isolation and storage of dental-derived stem cells is the most pressing issue that awaits resolution and the properties of supportive scaffold materials vary across different studies and remain inconsistent. …”
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Transition Metal(II) Complexes with Cefotaxime-Derived Schiff Base: Synthesis, Characterization, and Antimicrobial Studies by Aurora Reiss, Mariana Carmen Chifiriuc, Emilia Amzoiu, Cezar Ionuţ Spînu

“…All the synthesized complexes were tested for in vitro antibacterial activity against some pathogenic bacterial strains, namely Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Bacillus subtilis, and Staphylococcus aureus. …”
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SPD_0410 negatively regulates capsule polysaccharide synthesis and virulence in Streptococcus pneumoniae D39 by Ye Tao, Li Lei, Shuhui Wang, Xuemei Zhang, Yibing Yin, Yuqiang Zheng

“…Streptococcus pneumoniae capsular polysaccharide (CPS) is a crucial virulence factor for this pathogenic bacterium and is partially under transcriptional control. …”
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C-Reactive Protein in Human Atherogenesis: Facts and Fiction by Oliver Zimmermann, Kefei Li, Myron Zaczkiewicz, Matthias Graf, Zhongmin Liu, Jan Torzewski

“…Whereas initial experimental studies suggested a pathogenic role for CRP in atherogenesis, more recent genetic data from Mendelian randomization trials failed to provide evidence for a causative role of CRP in cardiovascular disease. …”
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Hygienic Evaluation of Electrolyzed or Ozonated Water-Washed Apples Stored under Different Temperatures and Relative Humidity Conditions by Jiao Wang, Yuequi Pei, Hyejin Kim, Sung-Yong Hong, Ae-Son Om

“…The presence of spoilage and pathogenic microorganisms is a concern for the safety of apples. …”
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Novel Mutations in the MKKS, BBS7, and ALMS1 Genes in Iranian Children with Clinically Suspected Bardet–Biedl Syndrome by Roghayeh Dehghan, Mahdiyeh Behnam, Mansoor Salehi, Roya Kelishadi

“…All variants were interpreted as pathogenic according to American College of Medical Genetics and Genomics (ACMG) guidelines and confirmed through Sanger sequencing. …”
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A Curious Case of MRSA Bacteremia and Septic Pulmonary Embolism Secondary to Peripheral Venous Catheter by Joshua Twito, Syeda Sahra, Abdullah Jahangir, Neville Mobarakai

“…Peripherally inserted catheters are an important portal for pathogen entry and need periodic site assessment and frequent evaluation of their need for insertion. …”
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Early detection of sepsis using machine learning algorithms by Rasha M. Abd El-Aziz, Alanazi Rayan

“…Sepsis triggers a complicated immune reaction to pathogenic microbes, which frequently leads to septic shock and organ failure. …”
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