Immobilization of NTPDase-1 from Trypanosoma cruzi and Development of an Online Label-Free Assay by Felipe Antunes Calil, Juliana Maria Lima, Arthur Henrique Cavalcante de Oliveira, Christiane Mariotini-Moura, Juliana Lopes Rangel Fietto, Carmen Lucia Cardoso

“…The enzyme nucleoside triphosphate diphosphohydrolase (NTPDase-1) from Trypanosoma cruzi acts as a pathogen infection facilitator, so it is a good target in the search for inhibitors. …”
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Correlation of blood coagulation parameters with comorbidities in COVID-19 patients: A retrospective study by Shuba N, Michael A

“…COVID-19 is a respiratory pathogenic strain with the potential to cause severe systemic inflammation and coagulopathy. …”
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Exploring glycolytic enzymes in disease: potential biomarkers and therapeutic targets in neurodegeneration, cancer and parasitic infections by Maura Rojas-Pirela, Diego Andrade-Alviárez, Verónica Rojas, Miguel Marcos, Daniel Salete-Granado, Marirene Chacón-Arnaude, María Á. Pérez-Nieto, Ulrike Kemmerling, Juan Luis Concepción, Paul A. M. Michels, Wilfredo Quiñones

“…Although energy transduction by glucose metabolism is the main function of this pathway, involvement in virulence, growth, pathogen–host interactions, immunomodulation and adaptation to environmental conditions are other functions attributed to this metabolic pathway. …”
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Polymorphonuclear Leukocytes or Hydrogen Peroxide Enhance Biofilm Development of Mucoid Pseudomonas aeruginosa by Qi Tan, Qing Ai, Qi Xu, Fang Li, Jialin Yu

“…Pseudomonas aeruginosa is an opportunistic pathogenic bacterium involved in many human infections, including pneumonia, diabetic foot ulcers, and ventilator-associated pneumonia. …”
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Cuminum Cyminum L Encapsulation on Perlite/calcium alginate/single walled carbon nanotubes -Glucose Composite: Fabrication, Characterization, Antibacterial and Antifungal Propertie... by Mahdieh Chegeni, Mozhgan Mehri, Zahra Shokri Rozbahani

“…Finally, this work demonstrates the efficient application of perlite/calcium alginate/single walled carbon nanotubes-Glucose for the encapsulation of cumin and pathogen detection.…”
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Multifactorial Origin of Exertional Rhabdomyolysis, Recurrent Hematuria, and Episodic Pain in a Service Member with Sickle Cell Trait by Nyamkhishig Sambuughin, Mingqiang Ren, John F. Capacchione, Ognoon Mungunsukh, Kevin Chuang, Iren Horkayne-Szakaly, Francis G. O’Connor, Patricia A. Deuster

“…The service member was taking prescription medications known to be associated with exertional rhabdomyolysis. He carried a pathogenic mutation, NPHS2 p.V260E, reported in nephropathy and a new variant p.R838Q in SCN11A, a gene involved in familial episodic pain syndrome. …”
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Potency of the Consortium of Pseudomonad fluorescent pf-142 and Bacillus mycoides Isolates Against Bacterial Wilt Disease In-Vitro by Yosua Nathanael Itona Sagala, Endang Triwahyu Prasetyawati, Yenny Wuryandari

“…The variables observed were the symptoms of attack and pathogenicity of R. solanacearum, compatibility and inhibitory rate of the consortium of Pseudomonad fluorescens pf-142 and B. mycoides against R. solanacearum. …”
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Sex-Related Differences in Immune Response and Symptomatic Manifestations to Infection with Leishmania Species by Ryan D. Lockard, Mary E. Wilson, Nilda E. Rodríguez

“…Ultimately, the combination of both pathogen and host factors determines the outcome of infection. …”
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YgaE Regulates Out Membrane Proteins in Salmonella enterica Serovar Typhi under Hyperosmotic Stress by Min Wang, Ping Feng, Xun Chen, Haifang Zhang, Bin Ni, Xiaofang Xie, Hong Du

“…Typhi) is a human-specific pathogen that causes typhoid fever. In this study, we constructed ΔygaE mutant and a microarray was performed to investigate the role of ygaE in regulation of gene expression changes in response to hyperosmotic stress in S. …”
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Microbial Translocation in Chronic Liver Diseases by Marilia Rita Pinzone, Benedetto Maurizio Celesia, Michele Di Rosa, Bruno Cacopardo, Giuseppe Nunnari

“…The intestinal microflora is not only involved in the digestion of nutrients, but also in local immunity, forming a barrier against pathogenic microorganisms. The derangement of the gut microflora may lead to microbial translocation, defined as the passage of viable microorganisms or bacterial products (i.e., LPS, lipopeptides) from the intestinal lumen to the mesenteric lymph nodes and other extraintestinal sites. …”
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Antimicrobial activity of Chitosan-silver nanoparticles made from jewelry industry silver waste by Perdana Muhammad Iqbal, Kusuma Ikhwan Yuda, Dwandaru Wipsar Sunu Brams, Yulianti Evy, Tóth Barbara, Csupor Dezső, Takó Miklós, Vágvölgyi Csaba

“…This study aimed to synthesize chitosan-silver nanoparticles (CS-AgNPs) from reusable silver waste of the jewelry industry and investigate their antimicrobial properties against pathogenic microorganisms. X-Ray diffraction (XRD) analysis was used to confirm the crystalline structure of the recycled silver, with a strong diffraction peak observed at 2θ=38.60°. …”
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Identification of a comprehensive set of transcriptional regulators involved in the long-term survivability of Escherichia coli in soil by Soma Nakamoto, Ikki Kobayashi, Koichi Watanabe, Takeru Kikuta, Sousuke Imamura, Tomohiro Shimada

“…These transcription factors are often global regulators and conserved among other pathogenic bacterial species. Taken together, we successfully identified a comprehensive set of transcription factors involved in the long-term survival of E. coli in soil. …”
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AI allows pre-screening of FGFR3 mutational status using routine histology slides of muscle-invasive bladder cancer by Pierre-Antoine Bannier, Charlie Saillard, Philipp Mann, Maxime Touzot, Charles Maussion, Christian Matek, Niklas Klümper, Johannes Breyer, Ralph Wirtz, Danijel Sikic, Bernd Schmitz-Dräger, Bernd Wullich, Arndt Hartmann, Sebastian Försch, Markus Eckstein

“…Abstract Pathogenic activating mutations in the fibroblast growth factor receptor 3 (FGFR3) drive disease maintenance and progression in urothelial cancer. 10–15% of muscle-invasive and metastatic urothelial cancer (MIBC/mUC) are FGFR3-mutant. …”
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Analysis of Mycoplasma gallisepticum Infection Factors in Commercial Layer Chicken Farm Using Analytical Hierarchy Process by Diyantoro Diyantoro, Eko Sugeng Pribadi

“…Background : Mycoplasma galliseptium (MG) is a pathogenic microbial often found in poultry farm industry. …”
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Preparation and Antibacterial Activity of Mixed Ligand Complexes of Co(II), Ni(II), Cu(II) and Cd(II) Derived from 1-Phenylazo-2-naphthol and Salicylaldehyde by S. A. I. Sharif, A. N. El-Tajoury, A. A. Elamari

“…The ligands and mixed ligand complexes have been tested on antibacterial activity against three strains of pathogenic bacteria such as Escherichia coli, Staphylococcus aureus and Pseudomonas aeruginosa…”
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Prevalence of red, orange, and green microbial complexes in periodontal pockets of chronic kidney disease patients on hemodialysis: a systematic review and meta-analysis by Diego José Gambin, Jayne de Oliveira Manica, Daniela Dal Olmo Merib, Caroline Mirek, Felipe Gomes Dallepiane, Thais Mageste Duque, João Paulo De Carli, Micheline Sandini Trentin

“…In the subgingival microbiota of CKD patients on hemodialysis, the red complex showed higher rates and prevalences, and Tannerella forsythia was the most common pathogen. …”
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Immune Modulation as Adjunctive Therapy for Pneumocystis pneumonia by Jing Wang, Terry W. Wright, Francis Gigliotti

“…Pneumocystis is an opportunistic fungal respiratory pathogen that causes life-threatening pneumonia (Pcp) in patients suffering from defects in cell-mediated immunity, including those with acquired immunodeficiency syndrome (AIDS) and immunosuppression secondary to chemotherapy or organ transplantation. …”
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MicroRNAs in Diabetic Kidney Disease by Rong Li, Arthur C. K. Chung, Xueqing Yu, Hui Y. Lan

“…Therefore, identification of the pathogenic role of microRNAs possesses an important clinical impact in terms of prevention and treatment of progression in diabetic kidney disease because it allows us to design novel and specific therapies and diagnostic tools for diabetic kidney disease.…”
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Cellular and humoral immune responses in cats vaccinated with feline herpesvirus 1 modified live virus vaccine by Hongchao Wu, Hongchao Wu, Peipei Qiao, Yunyu Chen, Caihong Liu, Ningning Huo, Hangtian Ding, Xiaojuan Wang, Lulu Wang, Xiangfeng Xi, Yuxiu Liu, Kegong Tian, Kegong Tian

“…Feline herpesvirus 1 (FHV-1) is an important pathogen causing infectious rhinotracheitis in felids, mainly infecting the upper respiratory tract and conjunctiva. …”
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Oxidative Stress Biomarkers: Establishment of Reference Values for Isoprostanes, AOPP, and NPBI in Cord Blood by Mariangela Longini, Elisa Belvisi, Fabrizio Proietti, Francesco Bazzini, Giuseppe Buonocore, Serafina Perrone

“…Oxidative stress (OS) is a common pathogenic factor involved in the onset of several diseases in humans, from immunologic disorders to malignancy, being a serious public health problem. …”
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