Portrait global de l’exposition aux contraintes psychosociales au travail des paramédics québécois by Sandrine Hegg-Deloye, Patrice Brassard, Jérôme Prairie, Dominique Larouche, Nathalie Jauvin, Angelo Tremblay, Philippe Corbeil

“…Psychosocial constraints at work are a major concern, since they can have a pathogenic effect on the mental and physical health of workers. …”
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Streptococcus intermedius Bacteremia and Liver Abscess following a Routine Dental Cleaning by Lachara V. Livingston, Elimarys Perez-Colon

“…In fact, the development of liver abscesses secondary to dental procedures is very rare in general, and there are only a few case reports in the literature describing this in relation to any pathogen. We present a rare case of S. intermedius bacteremia and liver abscess following a dental cleaning. …”
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Down but Not Out: The Consequences of Pretangle Tau in the Locus Coeruleus by Termpanit Chalermpalanupap, David Weinshenker, Jacki M. Rorabaugh

“…In this review, we combine the literature on how pathogenic tau affects forebrain neurons with the known properties and degeneration patterns of LC neurons to synthesize hypotheses on hyperphosphorylated tau-induced dysfunction of LC neurons and the prion-like spread of pretangle tau from the LC to the forebrain. …”
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Electroacupuncture Stimulation Suppresses Postoperative Inflammatory Response and Hippocampal Neuronal Injury by Xiang-feng Wang, Qin Lin, Guan-hui Wang, Gen-ming Zhan, Wei Liu, Zhi-wei Lin

“…These findings indicated the POCD was the synergistic outcome of anaesthesia and surgical stimulation but with different pathogenic mechanism. The surgery with mental tri-needles (surgery+MTN) group outperformed the surgery group in terms of cognitive function performance. …”
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A systematic review on malaria and Tuberculosis (TB) vaccine challenges in sub-Saharan African clinical trials. by Maonezi Abas Hamisi, Nur Ain Mohd Asri, Aini Syahida Mat Yassim, Rapeah Suppian

“…<h4>Conclusion</h4>Factors such as population characteristics, pathogen genetic diversity, vaccine nature, strategy, and formulation were associated with slow progress of the malaria and TB vaccine candidates in sub-Saharan African clinical trials.…”
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Microevolution during Chronic Infection May Lead T. asahii to Coexist with the Host by Gen Ba, Xuelian Lv, Xin Yang, Wenling Wang, Junhong Ao, Rongya Yang

“…Compared with the primary T. asahii strain, the microevolved strain induced much lower expression of TNF-α by mice bone marrow-derived DC and had a much superior survival rate, a total of 2212 significantly differentially expressed genes were identified in the microevolved strain, and functional analysis showed significance in the downregulated transcription and metabolic process, especially the valine, leucine, and isoleucine degradation pathways, which were associated with pathogenicity and virulence; hence, the results were highly consistent with the decreased immunogenicity and virulence of the microevolved strain. …”
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Deubiquitinases: Novel Therapeutic Targets in Immune Surveillance? by Gloria Lopez-Castejon, Mariola J. Edelmann

“…It occurs when the immune system recognizes Pathogen-Associated Molecular Patterns (PAMPs) or Damage-Associated Molecular Pattern (DAMPs) through the activation of Pattern Recognition Receptors. …”
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Drugs Involved in Dyslipidemia and Obesity Treatment: Focus on Adipose Tissue by Sofia Dias, Sílvia Paredes, Laura Ribeiro

“…Obesity and dyslipidemia are main features of metabolic syndrome, and both can present with adipose tissue dysfunction, involved in the pathogenic mechanisms underlying this syndrome. We revised the effects, and underlying mechanisms, of the current approved drugs for dyslipidemia and obesity (fibrates, statins, niacin, resins, ezetimibe, and orlistat; sibutramine; and diethylpropion, phentermine/topiramate, bupropion and naltrexone, and liraglutide) on adipose tissue. …”
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Green-Synthesized Sm3+-Doped ZnO Nanoparticles for Multifunctional Applications by Lavanya R., Ramakrishnappa T., Girish K. M., Suresh Kumar K., Basavaraju N., Shilpa B. M.

“…The antibacterial activity was performed against two pathogenic strains, i.e., Escherichia coli and Streptococcus aureus. …”
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Cepacia Syndrome in a Non-Cystic Fibrosis Patient by Naomi Hauser, Jose Orsini

“…The potential for this pathogen to infect non-cystic fibrosis patients is limited and its epidemiology is poorly understood. …”
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Chinese guidelines for the diagnosis and treatment of human immunodeficiency virus infection/acquired immunodeficiency syndrome (2024 edition) by Acquired Immunodeficiency Syndrome Professional Group, Society of Infectious Diseases, Chinese Medical Association; Chinese Center for Disease Control and Prevention, Wei Zhao

“…This edition of the Guidelines covers 14 sections: epidemiology, pathogenic characteristics, laboratory tests, pathogenesis, clinical presentation and staging, diagnostic criteria, common opportunistic infections, antiretroviral therapy, immune reconstitution inflammatory syndrome, incomplete immune reconstitution, AIDS-related neoplasms, prevention of mother-to-child transmission and conception in serodiscordant couples, pre- and post-exposure prophylaxis, and whole-course management of HIV infection. …”
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Seroprevalence of HCMV among Pregnant Women and Its relation to CD4 and CRP by Staar Mohammed Qader

“…The HCMV is a widespread viral pathogen characterized by strict host specificity and is limited to humans. …”
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Periodontal Status in Smokers and Nonsmokers: A Clinical, Microbiological, and Histopathological Study by Maddipati Sreedevi, Alampalli Ramesh, Chini Dwarakanath

“…It is quite possible that many of the pathogenic mechanisms involved in tissue degradation in periodontitis in smokers could be quite different from those in nonsmokers.…”
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Preventing Foodborne Illness: E. coli O157:H7 by Keith R. Schneider, Renée Goodrich Schneider, Ploy Kurdmongkoltham, Bruna Bertoldi

“… This seven-page fact sheet discusses the common foodborne pathogen E. coli O157:H7, especially as it concerns food handlers, processors and retailers. …”
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Pathogenesis of Helicobacter pylori-Related Gastroduodenal Diseases from Molecular Epidemiological Studies by Yoshio Yamaoka

“…Helicobacter pylori is a major human pathogen that infects the stomach and produces inflammation that is responsible for various gastroduodenal diseases. …”
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Colitis in spondyloarthritis by Muhammed Hafis, Vikas Agarwal

“…Several therapeutic targets have emerged in the last few years based on the understanding of the pathogenic mechanism and have considerably changed the management of both IBD and SpA.…”
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MPO Expression of Background Neutrophils in MPO Negative Acute Promyelocytic Leukemia, An Easy Clue to Corroborate a Challenging Diagnosis: A Case Report and Review of Literature by Kritika Krishnamurthy, Jui Choudhuri, K. H. Ramesh, Yanhua Wang

“…Acute promyelocytic leukemia (APL) is characterized by the pathogenic driver fusion transcript PML-RARA resulting from the t(15;17) translocation. …”
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Drug Target Identification and Prioritization for Treatment of Ovine Foot Rot: An In Silico Approach by Abhishek Acharya, Lalit C. Garg

“…In addition, a total of 13 targets were identified that are common in at least 10 pathogenic bacterial species.…”
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Combination of metagenomic next-generation sequencing and morphology for identifying Coccidioides immitis: a case report by Hong Liu, Kaixin Zhou, Chaoran Zhong, Ming Guan

“…As coccidioidomycosis is a rare disease in China, its pathogen-specific diagnostic methods are limited. In this case, we combined two universal methods, mNGS and traditional morphological observation, to confirm the diagnosis. …”
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Selective Induced Altered Coccidians to Immunize and Prevent Enteritis by Helieh S. Oz

“…Chicks received oral gavage immunized with serial low doses of normal or altered organisms or sham treatment and were challenged with high infective normal organisms to compare pathogenicity and immunogenicity. Mature induced altered forms of E. tenella and E. necatrix lacked developmental stage of “sporocysts” and contained free sporozoites. …”
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