Cardiopulmonary bypass associated acute kidney injury: better understanding and better prevention by Xutao Yang, Li Zhu, Hong Pan, Yi Yang

“…Finally, we explore current interventions aimed at preventing and attenuating renal impairment related to CPB, and presenting these measures from three perspectives: (1) avoiding CPB to eliminate the fundamental impact on renal function; (2) optimizing CPB by adjusting equipment parameters, optimizing surgical procedures, or using improved materials to mitigate kidney damage; (3) employing pharmacological or interventional measures targeting pathogenic factors.…”
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Peripheral proteinopathy in neurodegenerative diseases by Bin Xu, Xia Lei, Ying Yang, Jiayi Yu, Jun Chen, Zhi Xu, Keqiang Ye, Jing Zhang

“…This review summarizes the distribution, transportation pathways, and pathogenic mechanisms of several neurodegenerative disease-related pathological proteins in the periphery, proposing that targeting these peripheral pathological proteins could be a promising strategy for preventing and managing neurological diseases.…”
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Empedobacter brevis Bacteremia in a Patient Infected with HIV: Case Report and Review of Literature by Syed Bokhari, Naeem Abbas, Manisha Singh, Richard B. Cindrich, Cosmina Zeana

“…In conclusion, E. brevis is an emerging pathogen that can cause serious health care associated infections.…”
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In vivo regulation of the monocyte phenotype by Mycobacterium marinum and the ESX-1 type VII secretion system by Kristina Munke, Line Wulff, Julia Lienard, Fredric Carlsson, William W. Agace

“…Abstract Pathogenic mycobacteria require the conserved ESX-1 type VII secretion system to cause disease. …”
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A note on dynamics of an age-of-infection cholera model by Jinliang Wang, Ran Zhang, Toshikazu Kuniya

“…The model is incorporated with both the infection age of infectious individuals and biological age of pathogen in the environment. The basic reproduction number is proved to be a sharp threshold determining whether or not cholera dies out. …”
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Manipulation of Type I Interferon Signaling by HIV and AIDS-Associated Viruses by Buyuan He, James T. Tran, David Jesse Sanchez

“…However, as additional studies into the function of Type I Interferons progressed, it was also seen that pathogenic viruses have coevolved to encode potent mechanisms allowing them to evade or suppress the impact of Type I Interferons on their replication. …”
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Genomic analysis of antimicrobial resistant Escherichia coli isolated from manure and manured agricultural grasslands by C. Tyrrell, C. M. Burgess, F. P. Brennan, D. Münzenmaier, D. Drissner, R. J. Leigh, F. Walsh

“…The environment can harbour Escherichia coli that are pathogenic or commensal. Escherichia coli is used as an indicator of environmental faecal contamination. …”
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Antifungal Resistance and New Strategies to Control Fungal Infections by Patrick Vandeputte, Selene Ferrari, Alix T. Coste

“…Discovery of new putative antifungal targets is performed through genome-wide approaches for a better understanding of the human pathogenic fungi biology.…”
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The Association Between Human Cytomegalovirus and Salivary Gland Cancer: An Analytical Study and Literature Review by Hagir Abd Rahman Mahmoud, Ahmed Mohamed Suleiman, Elwaleed Mohamed Elamin, Sawsan Abdel Rahim Mohammed

“… Background: Human cytomegalovirus (HCMV) is a widespread human pathogen that triggers varying clinical symptoms depending on the host’s age and immune status. …”
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A Case of Cardiac Arrest during C1 Laminectomy for Irreducible Atlantoaxial Subluxation by Yosuke Shibao, Masao Koda, Keita Nakayama, Tomoyuki Asada, Kosuke Sato, Mamoru Kono, Fumihiko Eto, Kentaro Mataki, Hiroshi Kumagai, Katsuya Nagashima, Kousei Miura, Hiroshi Noguchi, Hiroshi Takahashi, Toru Funayama, Tetsuya Abe, Masashi Yamazaki

“…There was no postoperative worsening of neurological symptoms, and the improvement of sensory and motor palsy was favorable. The pathogenic mechanism was presumed to be trigeminocardiac reflex. …”
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Immunomagnetic Separation of Salmonella Typhimurium Based on Microfluidic Chip by JIN Yan, WANG Jingyi, CHENG Jianing, YU Lemin, ZHANG Bichen, ZHANG Yibo, XU Tongyu

“…This highly integrated immunomagnetic separation microfluidic system can enrich target bacteria from complex food matrices rapidly and accurately, thus providing an effective solution for the rapid detection of foodborne pathogenic bacteria, which is of great significance in addressing public health problems caused by foodborne diseases.…”
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Cotton (Gossypium hirsutum) Cultivars Exhibiting Tolerance to the Reniform Nematode (Rotylenchulus reniformis) by Julie A. Blessitt, Salliana R. Stetina, Ted P. Wallace, Peggy T. Smith, Gabriel L. Sciumbato

“…Though they will not suppress the reniform nematode population, these cultivars can help reduce economic losses attributed to this pathogen in the Midsouth region of the USA.…”
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Juvenile Hemochromatosis due to a Homozygous Variant in the HJV Gene by María-Belén Moreno-Risco, Manuel Méndez, María-Isabel Moreno-Carralero, Ana-María López-Moreno, José-Manuel Vagace-Valero, María-José Morán-Jiménez

“…Juvenile hemochromatosis type 2a and 2b is an autosomal recessive disease caused by pathogenic variants in HJV and HAMP genes, respectively. …”
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Classification of distinct tendinopathy subtypes for precision therapeutics by Chenqi Tang, Zetao Wang, Yuanhao Xie, Yang Fei, Junchao Luo, Canlong Wang, Yue Ying, Peiwen He, Ruojing Yan, Yangwu Chen, Jiayun Huang, Yiwen Xu, Zicheng Wang, Boon Chin Heng, Hengzhi Liu, Jianyou Li, Zi Yin, Haobo Wu, Weishan Chen, Hongwei Ouyang, Xiao Chen, Weiliang Shen

“…Hence, this study attempted a classification of 126 diseased tendons into three distinct subtypes with opposite pathogenic mechanisms based on transcriptomic and clinical features. …”
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Strategies for the Development of Bioprotective Cultures in Food Preservation by Luana Virgínia Souza, Evandro Martins, Isabella Maria Fernandes Botelho Moreira, Antônio Fernandes de Carvalho

“…In this context, the lactic acid bacteria (LAB) have been extensively prospected as a bioprotective culture, as they have a long history in food production and their antimicrobial activity against spoilage and pathogenic microorganisms is well established. However, to make LAB cultures available in the market is not that easy, the strains should be characterized phenotypically and genotypically, and studies of safety and technological application are necessary to validate their bioprotection performance. …”
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Compound Heterozygous Mutations in TMC1 and MYO15A Are Associated with Autosomal Recessive Nonsyndromic Hearing Loss in Two Chinese Han Families by Pengcheng Xu, Jun Xu, Hu Peng, Tao Yang

“…The two novel mutations identified in this study, p.M413T in TMC1 and p.R1407T in MYO15A, are classified as likely pathogenic according to the guidelines of ACMG. Our study expanded the mutation spectrums of TMC1 and MYO15A and illustrated that genotype-phenotype correlation in combination with next-generation sequencing may improve the accuracy for genetic diagnosis of deafness.…”
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Potential of ethyl acetate and methanol extract from Eupatorium odoratum and Morinda citrifolia plants as Fusarium Oxysporum fungicide by Puspitasari Etika Dyah, Ma’rifah Destri Ratna, Matsjeh Sabirin

“…Fusarium oxysporum is a significat plant pathogen that affects various crops. Fusarium causing diseases and substantial agricultural losses. …”
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Toll-Like Receptors and Diabetic Nephropathy: A Review of Recent Advances by Mohammad Sadra Gholami Chahkand, Yasaman Tavakoli, Ava Aghakhani, Monireh Askarzadeh, Hosein Azimi, Nogol Ghalamkarpour, Alaleh Alizadeh, Iman Archin, Sajad Kermani, Akram Ansari, Mohadeseh Poudineh, Zahra Mali, Elaheh Foroughi, Gisou Erabi, Seyed Amirhossein Mazhari, Mohammad Sadegh Fallahi, Niloofar Deravi, Parisa Alsadat Dadkhah

“…Toll-like receptors (TLRs) are innate immune receptors that recognize pathogen- and danger-associated molecular patterns, which can result in an inflammatory response. …”
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Gradual Increase of High Mobility Group Protein B1 in the Lungs after the Onset of Acute Exacerbation of Idiopathic Pulmonary Fibrosis by Masahito Ebina, Hiroyuki Taniguchi, Taku Miyasho, Shingo Yamada, Naoko Shibata, Hiromitsu Ohta, Shu Hisata, Shinya Ohkouchi, Tsutomu Tamada, Hidekazu Nishimura, Akitoshi Ishizaka, Ikuro Maruyama, Yoshinori Okada, Kondo Takashi, Toshihiro Nukiwa

“…These results suggest pathogenic roles for HMGB1 and MCP-1 in the late phase of acute exacerbation of IPF.…”
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Isolation of probiotics bacterium from coral reef for controlling vibriosis in tiger shrimp (Penaeus monodon) larvae by Ade Dwi Sasanti, . Widanarni, . Sukenda

“… Pathogenic Vibrio, especially luminous Vibrio harveyi, could cause mass mortality in tiger shrimp culture. …”
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