Study on the pathogenesis of pathophysiological changes of burn systemic infection by Li Ao (Ngao), Huang Yuesheng, Yang Zongcheng

“…These suggested that TXA2/PGI2. imbalance promoting microaggregate and thrombus formation may be one of the pathogenic effects of toxic shock and MOF in burn patients.…”
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Macrophages in sepsis-induced acute lung injury: exosomal modulation and therapeutic potential by Kaiying Lv, Qun Liang

“…It highlights the regulation of macrophages by exosomes derived from pathogenic germs, neutrophils, alveolar epithelial cells, and mesenchymal stromal cells. …”
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Meningococcal B Vaccination (4CMenB) in Infants and Toddlers by Susanna Esposito, Claudia Tagliabue, Samantha Bosis

“…Neisseria meningitidis is a Gram-negative pathogen that actively invades its human host and leads to the development of life-threatening pathologies. …”
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A Rare Interstitial Duplication of 8q22.1–8q24.3 Associated with Syndromic Bilateral Cleft Lip/Palate by Regina Ferreira Rezek, Ana Angélica Rodrigues Abbas, Juliana Forte Mazzeu, Siliana Maria Duarte Miranda, Cibele Velloso-Rodrigues

“…Chromosome microarray analysis evidenced a 49 Mb duplicated segment of chromosome 8q with no pathogenic imbalances on chromosome 22. Two siblings also carry the balanced translocation. …”
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Organ-based characterization of B cells in patients with systemic lupus erythematosus by Yunan Wang, Rui Zhao, Qian Liang, Shiwen Ni, Mei Yang, Liwei Qiu, Juan Ji, Zhifeng Gu, Chen Dong

“…Currently, there is no systematic review that examines the specificity of B cell characteristics and pathogenic mechanisms across various organs. This paper reviews current research on B cells in lupus patients and summarizes the distinct characteristics of B cells in different organs. …”
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The Role of p38 MAPK in the Aetiopathogenesis of Psoriasis and Psoriatic Arthritis by Athanasios Mavropoulos, Eirini I. Rigopoulou, Christos Liaskos, Dimitrios P. Bogdanos, Lazaros I. Sakkas

“…Emerging data suggest a potential pathogenic role for mitogen activated protein kinases p38 (p38 MAPK) extracellular signal-regulated kinase 1/2 (ERK1/2), and c-Jun N-terminal kinase (JNK) in the development of psoriasis. …”
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A case of stroke as a unique sign of subclinical infective endocarditis by Abiotrophia defectiva: a case report by Silvia Puxeddu, Valeria Virdis, Daniele Sacco, Mario Depau, Alessandro M. Atzei, Lorella Pisano, Marcello Di Rosa, Stefania Vacquer, Giorgio Accardi, Emiliano M. Cirio, Aldo Manzin, Cristiana Marinelli, Fabrizio Angius

“…Abstract Purpose Here we describe a patient admitted for a stroke that was unexpectedly correlated with subclinical infective endocarditis attributable to a rarely opportunistic pathogen, Abiotrophia defectiva. Case report A 75-year-old man presented with a stroke. …”
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Bilateral Glaucoma as Possible Additional Feature for PGAP3-Associated Hyperphosphatasia by Osama Obaid, Reem Batawi, Heba Alqurashi, Thana Ewis, Ahmad A. Obaid

“…Whole exome sequencing revealed a possible pathogenic variant of PGAP3 in a homozygous state (c.320C > T, p.Ser107Leu) which supported the diagnosis of HPRMS type-4. …”
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RNA Degradation in Staphylococcus aureus: Diversity of Ribonucleases and Their Impact by Rémy A. Bonnin, Philippe Bouloc

“…Here we present an overview on the diversity of ribonucleases (RNases) and their impact at the posttranscriptional level in the human pathogen Staphylococcus aureus. RNases in prokaryotes have been mainly studied in the two model organisms Escherichia coli and Bacillus subtilis. …”
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Inflammasomes in neurodegenerative diseases by Qianchen Wang, Songwei Yang, Xuan Zhang, Shanshan Zhang, Liping Chen, Wanxue Wang, Naihong Chen, Jiaqing Yan

“…Abstract Inflammasomes represent a crucial component of the innate immune system, which respond to threats by recognizing different molecules. These are known as pathogen-associated molecular patterns (PAMPs) or host-derived damage-associated molecular patterns (DAMPs). …”
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The possible therapeutic role of advanced glycation end-product inhibitors in ischemic stroke by Nada H. Aljarba, Hayder M. Al-Kuraishy, Ali I. Al-Gareeb, Mustafa M. Shokr, Marios Papadakis, Athanasios Alexiou, Mubarak Alruwaili, Mohammed Alrouji, Mohammed S. Alshammari, Gaber El-Saber Batiha

“…Many studies highlighted that AGEs serum levels are correlated with the incidence, pathogenicity, and severity of AIS. However, the relationship between AGEs and AIS is not elucidated completely. …”
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Diagnosis and treatment of the functional dyspepsia: clinical guidelines of the Russian Gastroenterological Association by V. T. Ivashkin, I. V. Mayev, A. A. Sheptulin, T. L. Lapina, A. S. Trukhmanov, I. M. Kartavenko, V. A. Kiprianis, O. Z. Okhlobystina

“…It’s etiology includes genetic predisposition, bad habits, previous intestinal infections, psychosocial factors. The basic pathogenic factors may include HCl hypersecretion, stomach and duodenal dysmotility and visceral hypersensitivity. …”
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Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membrane. by Lilli Stergiou, Manuel Bauer, Waltraud Mair, Damaris Bausch-Fluck, Nir Drayman, Bernd Wollscheid, Ariella Oppenheim, Lucas Pelkmans

“…Simian Virus 40 (SV40) is a paradigm pathogen with multivalent binding sites for the sphingolipid GM1, via which it induces its endocytosis for infection. …”
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Dengue infection changes the expressions of CD154 and CD148 in human platelets by Sayali Vedpathak, Sonali Palkar, AkhileshChandra Mishra, Vidya A Arankalle, Shubham Shrivastava

“…Platelets recognize dengue virus through the DC-SIGN receptor. Upon pathogen recognition, platelets rapidly modulate the expression of adhesion molecules to trigger immune cell interactions and regulate the immune response. …”
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The Role of RaxST, a Prokaryotic Sulfotransferase, and RaxABC, a Putative Type I Secretion System, in Activation of the Rice XA21-Mediated Immune Response by Pamela C. Ronald

“…We have recently demonstrated that the plant pathogen Xanthomonas oryzae pv. oryzae (Xoo) carries a functional sulfotransferase (RaxST). raxST is required for activation of rice Xa21-mediated immunity indicating the critical, but unknown, function of raxST in mediating the Xoo/rice interaction. …”
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Two Pediatric Cases of Primary Ciliary Dyskinesia Caused by Loss-of-Function Variants in Oral-Facial-Digital Syndrome Gene, OFD1 by Yifei Xu, Yuki Tsurinaga, Tsubasa Matsumoto, Ryuji Muta, Taichi Yano, Hiroshi Sakaida, Sawako Masuda, Koki Ueda, Guofei Feng, Shimpei Gotoh, Satoru Ogawa, Makoto Ikejiri, Kaname Nakatani, Mizuho Nagao, Masaki Tanabe, Kazuhiko Takeuchi

“…We report two male pediatric cases of PCD caused by hemizygous pathogenic variants in the OFD1 centriole and centriolar satellite protein (OFD1) gene. …”
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Generation and heterozygous repair of human iPSC lines from two individuals with the neurodevelopmental disorder, TRAPPC4 deficiency by Riley Hall, Tim Sikora, Annabelle Suter, Jia Yi Kuah, John Christodoulou, Nicole J Van Bergen

“…We have generated stem cells from fibroblasts of two individuals with the same homozygous TRAPPC4 c.454 + 3A > G pathogenic variant and used CRISPR/Cas9 editing to generate heterozygous gene-corrected isogenic controls. …”
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Use of Gibberellic Acid to Improve Health and Productivity of HLB-Affected ‘Valencia’ Trees by Tripti Vashisth

“…Although GA treatment cannot eradicate the pathogen that causes HLB in affected citrus trees, the current GA application recommendation can provide growers an alternative remedy to alleviate HLB symptoms and ameliorate the production issues that are associated with the disease, including yield decline, reduced fruit size, increased preharvest fruit drop, and rapid tree health decline, until a cure for HLB or complete HLB-resistant cultivars can be developed. …”
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Prebiotic products based on kepok banana starch (Musa paradisiaca Formatypica) and moringa (Moringa oleifera) as functional food for female wistar rats by Luthfiyah Fifi, Ikayanti Retno, Dwipajati

“…Results showed significant differences in gut microbiota with MBS consumption, with higher concentrations of beneficial bacteria and reduced levels of pathogenic bacteria observed in the group receiving the highest MBS dose. …”
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Gray Leaf Spot of St. Augustinegrass: Cultural and Chemical Management Options by Philip Harmon, Lawrence Datnoff, Russell Nagata, Matt Brecht, Carol Stiles

“…However, from the mid-Atlantic states north and throughout much of the Midwest, the pathogen blights the cool season species of annual and perennial ryegrass as well as tall fescue. …”
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