Isolation of Mesophyll Protoplasts from Leaves of <i>Dalbergia sissoo</i> Roxb by I Mukhtar, R Bajwa, G Nasim

“…In case of die back, Dalbergia is facing the threat of destruction in its natural habitats due to lack of potential pathogenicity test which is the major bottleneck in pathogen assessment and tree improvement programmes. …”
Get full text

Modelling the human immune response mechanisms to mycobacterium tuberculosis infection in the lungs by Gesham Magombedze, Winston Garira, Eddie Mwenje

“…We use the model topredict disease progression scenarios, including primary, latency or clearance.Model analysis shows that occurrence of active disease is much attributedto the Mtb pathogen ability to persist outside the intracellular environmentand that high levels of CTLs result in latent TB, while low levels of CTLsresult in active TB. …”
Get full text

Dendritic Cells and Leishmania Infection: Adding Layers of Complexity to a Complex Disease by Daniel Feijó, Rafael Tibúrcio, Mariana Ampuero, Cláudia Brodskyn, Natalia Tavares

“…Leishmaniasis is a group of neglected diseases whose clinical manifestations depend on factors from the host and the pathogen. It is an important public health problem worldwide caused by the protozoan parasite from the Leishmania genus. …”
Get full text

Role of Verticillium dahliae effectors in interaction with cotton plants by Lingling Yang, Tingyuan Fu, Ruichen Sha, Guihuan Wei, Yuhe Shen, Zhen Jiao, Bing Li

“…However, the widespread and destructive soilborne pathogen, Verticillium dahliae, causes Verticillium wilt, leading to severe yield losses and reduced fiber quality of cotton. …”
Get full text

Computational design of multi-epitope vaccine against Hepatitis C Virus infection using immunoinformatics techniques. by Sara Zubair, Fahed Parvaiz, Turki Abualait, Khalid Al-Regaiey, Tasneem Anwar, Mahnoor Zafar, Imdad Kaleem, Shahid Bashir

“…Hepatitis C Virus (HCV) is a blood borne pathogen that affects around 200 million individuals worldwide. …”
Get full text

Inflammation and Immune Response in COPD: Where Do We Stand? by Nikoletta Rovina, Antonia Koutsoukou, Nikolaos G. Koulouris

“…Furthermore, viral and bacterial infections interfere with the chronic inflammation seen in stable COPD and exacerbations via pathogen-associated molecular patterns (PAMPs). Finally, autoimmunity is another novel aspect that may play a critical role in the pathogenesis of COPD. …”
Get full text

Preserving Darwin’s fox: genomic tools for the conservation of South America’s most endangered canid by Cristóbal Valenzuela-Turner, José Horacio Grau, Jörns Fickel, Jörns Fickel, Daniel W. Förster

“…Here we highlight the potential of HTS to address these challenges, such as clarifying its taxonomy, demographic history, geographic distribution, population structure, genetic diversity, and pathogen exposure. Integrating molecular data into conservation planning will be pivotal in ensuring the long-term survival of Darwin’s fox by identifying priorities for targeted management interventions, highlighting areas of critical habitat for conservation, and guiding genetic rescue efforts to enhance genetic diversity and resilience.…”
Get full text

Immunity in the Cervix: Interphase between Immune and Cervical Epithelial Cells by Jorgelina Barrios De Tomasi, Michael Makokha Opata, Chishimba Nathan Mowa

“…These (ways) include mounting physical (intercellular junctions, secretion of mucus) and immune barriers (pathogen-recognition receptor-mediated pathways), which collectively and ultimately lead to the release of specific chemokines and or cytokines. …”
Get full text

Staphylococcus aureus Infections in the Paediatric Intensive Care Unit: Illustrated Cases by Kam Lun Hon, Ronald C. M. Fung, Karen K. Y. Leung, Alexander K.C. Leung, Wun Fung Hui, Wing Lum Cheung

“…Staphylococcus aureus is known to be one of the most common gram-positive microorganisms and an important pathogen associated with sepsis and toxic shock. We present four anonymized consecutive cases in a paediatric intensive care unit (PICU) to illustrate the different clinical manifestations of staphylococcal infections, including local infection versus systemic infection, toxic shock versus septic shock, and osteomyelitis. …”
Get full text

Activation of Macrophages by Oligomeric Proteins of Different Size and Origin by Indrė Dalgėdienė, Asta Lučiūnaitė, Aurelija Žvirblienė

“…Activation of macrophages is one of the key processes in generating the immune response against pathogens or misfolded/aggregated otherwise unharmful host’s proteins. …”
Get full text

First VIM-producing representative of Pseudomonas putida group from the largest Bulgarian hospital by Atanaska Petrova, Ivan N. Ivanov, Liubomir Paunov, Angel Uchikov, Ivan Stoikov, Todor Kantardjiev, Marianna Murdjeva

“…Despite P. putida not being a common pathogen, it still could survive in hospital conditions causing difficult-to-treat infections and becoming a source of resistant genes, including MBL-encoding genes.…”
Get full text

Severe Case of Plasmodium falciparum Malaria in a Pregnant Woman from Nigeria by Kruti Yagnik, Bilal Farooqi, Molly W. Mandernach, Anthony P. Cannella, Gautam Kalyatanda

“…Human malaria has arguably affected more of human history than any other pathogen. Pregnant women have a higher risk of developing severe malaria as well as the risk of severe complications. …”
Get full text

Receptor for Advanced Glycation End Products and Its Involvement in Inflammatory Diseases by Yaw Kuang Chuah, Rusliza Basir, Herni Talib, Tung Hing Tie, Norshariza Nordin

“…These effects endow RAGE with the role in the signal transduction from pathogen substrates to cell activation during the onset and perpetuation of inflammation. …”
Get full text

Whole transcriptomic and proteomic analyses of an isogenic M. tuberculosis clinical strain with a naturally occurring 15 Kb genomic deletion. by Carla Duncan, Frances B Jamieson, JoLynn Troudt, Linda Izzo, Helle Bielefeldt-Ohmann, Angelo Izzo, Carolina Mehaffy

“…These include the ability of the host to control the infection which may directly relate to nutritional status, presence of co-morbidities and genetic predisposition. Pathogen factors, in particular the ability of different Mycobacterium tuberculosis strains to respond to the harsh environment of the host granuloma, which includes low oxygen and nutrient availability and the presence of damaging radical oxygen and nitrogen species, also play an important role in the success of different strains to cause disease. …”
Get full text

Diversity of Rust Fungi with Special Emphasis on <i>Hyalopsora erlangensis</i> Causing Disease in <i>Cystopteris chinensis</i> by An Yu, Xia Zhao, Xiaohong Chen

“…Our research not only identifies the pathogen but also offers fundamental insights for fern rust diversity, and the future management and conservation of this endangered fern, aiming to mitigate the impact of this devastating rust.…”
Get full text

Brain Imaging and Ultrastructural Studies of the Effect of Electroacupuncture on Improving Learning and Memory Impairments in the Focal Cerebral Isch-emia Rats by Ruhui LIN, Kunqiang YU, Xiaojie LI, Congkuai ZHAO, Chunyan LI

“…Objective:To investigate the effect of electroacupuncture(EA)at <italic>Baihui</italic> and <italic>Shenting</italic> on the learning and memory ability in focal cerebral ischemia(MCAO)rats, and then explore the underlying mechanism.Methods:Forty-five male SPF(Specific Pathogen Free)rats were randomly divided into the sham operation control group(SC group), the ischemia model group(IC group)and the electroacupuncture group(EA group). …”
Get full text

The Prevalence of Shiga Toxin-Producing Escherichia coli and Enteropathogenic Escherichia coli Isolated from Raw Chicken Meat Samples by Omid Zarei, Leili Shokoohizadeh, Hadi Hossainpour, Mohammad Yousef Alikhani

“…Shiga toxin-producing Escherichia coli (STEC) is known as a crucial zoonotic food-borne pathogen. A total of 257 raw chicken meat samples were collected from different markets in Hamadan, west of Iran, from January 2016 to May 2017. …”
Get full text

One-year surveillance of Chlamydia spp. infection in stray cats from northeastern Italy by Laura Bellinati, Letizia Ceglie, Elisa Mazzotta, Mery Campalto, Laura Lucchese, Alda Natale

“…For this reason, stray cats appear to be particularly susceptible to this pathogen. Aim of the study was to identify the molecular occurrence of Chlamydiaceae in stray and colony cats. …”
Get full text

Mycophenolate Mofetil and Clostridium difficile-associated Colitis by A. I. Dolgushina, A. A. Selyanina, E. A. Mezenceva, A. G. Vasilenko, L. I. Pozdeeva, L. Yu. Zhuravleva, E. R. Olevskaya, E. A. Fedorova

“…Catarrhal ulcerative colitis in colonoscopy, C. difficile toxins in pathogen stool panel. Ulcerative, ischaemic colitises and the graft-versus-host disease were ruled out in examination. …”
Get full text

ANTHRAX GLOBAL EPIZOOTOLOGY. 1. SUSCEPTIBLE ANIMALS by Makhamat Nguerabe Yamtitina, V. V. Makarov

“…The susceptibility of animal species to anthrax depends not only on the dose, but also on the form (vegetative or spore) of the anthrax bacterium, the mode of infection, and the site of introduction of the pathogen into the organism. Anthrax affects mammals of 19 species: mostly cattle, which are intermediate hosts and hosts in the global parasitoid system; sheep and goats, horses, pigs, many species of wild ruminants and herbivorous, mostly deer, gazelles, bisons, hippopotamuses and even elephants, as well as Carnivora. …”
Get full text