The Microbiome-Gut-Brain Axis, Nutrition and Parkinson’s Disease by Jevgenija Guk, Rūta Kaladytė Lokominienė, Dalius Jatužis

“…According to Braak’s hypothesis, an unknown pathogen in the gastrointestinal tract may initiate the production of pathogenic α synuclein, which would subsequently spread to the central nervous system. …”
Get full text

A Systemic Network Triggered by Human Cytomegalovirus Entry by Anyou Wang, Li Ren, Hong Li

“…Here, by employing systems biology approaches, we reveal a systemic virus-entry network initiated by human cytomegalovirus (HCMV), a widespread opportunistic pathogen. This network contains ten functional modules (i.e., groups of proteins) that coordinately respond to HCMV entry. …”
Get full text

A Rare Case of Mediastinal Bronchogenic Cyst Infected by Salmonella enteritidis by Jasleen Kaur, Philip J. McDonald, Ravinder D. Bhanot, Reda A. Awali, Sorabh Dhar, James Rowley

“…Gram-positive, Gram-negative, and mycobacterial infections have been reported, though frequently a pathogen is not identified. We present the case of a 46-year-old female with known history of bronchogenic cyst who presented with suspected postobstructive pneumonia. …”
Get full text

Gene Technology for Papaya Ringspot Virus Disease Management by Md. Abul Kalam Azad, Latifah Amin, Nik Marzuki Sidik

“…The genetic diversity of PRSV depends upon geographical distribution and the influence of PRSV disease management on a sequence of PRSV isolates. The concept of pathogen-derived resistance has been employed for the development of transgenic papaya, using a coat protein-mediated, RNA-silencing mechanism and replicase gene-mediated transformation for effective PRSV disease management. …”
Get full text

Burkholderia Aortic Aneurysm: A Case Report and Review of the Literature by Sreelakshmi Panginikkod, Aishwarya Ramachandran, Pratyusha Bollimunta, Roshanak Habibi, Roshan Kumar Arjal, Venu Gopalakrishnan

“…It is a rare imported pathogen in the United States and is a potential bioterror agent. …”
Get full text

Viral diversity and phloem transcriptional changes in grapevine Shiraz disease infected vines by Cristobal Onetto, Dilrukshi Nagahatenna, Yeniu Mickey Wang, Vinay Pagay, Anthony Borneman

“…Similar to other plant pathogen infections, SD upregulated genes associated with the systemic acquired resistance (SAR) mechanism and downregulated genes related to vine immunity. …”
Get full text

Cytokines and Chemokines at the Crossroads of Neuroinflammation, Neurodegeneration, and Neuropathic Pain by Geeta Ramesh, Andrew G. MacLean, Mario T. Philipp

“…Although inflammation may induce beneficial effects such as pathogen clearance and phagocytosis of apoptotic cells, uncontrolled inflammation can result in detrimental outcomes via the production of neurotoxic factors that exacerbate neurodegenerative pathology. …”
Get full text

Bacteremia due to Leuconostoc pseudomesenteroides in a Patient with Acute Lymphoblastic Leukemia: Case Report and Review of the Literature by Kazuko Ino, Kazunori Nakase, Kei Suzuki, Akiko Nakamura, Atsushi Fujieda, Naoyuki Katayama

“…Physicians should be aware of Leuconostoc species as causative pathogen if they encounter Gram-positive cocci bacteremia resistant to standard antibiotics such as vancomycin and teicoplanin, especially in patients with hematologic malignancies.…”
Get full text

<i>Helicobacter pylori</i> HP0135 Is a Small Lipoprotein That Has a Role in Outer Membrane Stability by Doreen Nguyen, Rachel G. Ivester, Kyle Rosinke, Timothy R. Hoover

“…<i>Helicobacter pylori</i> is a Gram-negative bacterium and human pathogen that is linked to various gastric diseases, including peptic ulcer disease, chronic gastritis, and gastric cancer. …”
Get full text

The Immune Response and Its Therapeutic Modulation in Bronchiectasis by Massoud Daheshia, James D. Prahl, Jacob J. Carmichael, John S. Parrish, Gilbert Seda

“…Bronchiectasis (BC) is a chronic pulmonary disease with tremendous morbidity and significant mortality. As pathogen infection has been advocated as a triggering insult in the development of BC, a central role for the immune response in this process seems obvious. …”
Get full text

Septic Shock Induced by Bacterial Prostatitis with Morganella morganii subsp. morganii in a Posttransplantation Patient by Xiaofan Li, Jianhui Chen

“…Taken together, Morganella morganii should be considered a possible pathogen when immunocompromised patients develop prostatitis. …”
Get full text

Optimal Pest Control Strategies with Cost-effectiveness Analysis by Ihza Rizkia Fitri, Farida Hanum, Ali Kusnanto, Toni Bakhtiar

“…A model was built to describe the interaction between plants and insects as well as the circulation of the pathogen. Optimal control measures are sought in such a way they maximize the healthy plant density jointly with the pests’ density under the lowest possible control efforts. …”
Get full text

Empedobacter brevis Bacteremia in a Patient Infected with HIV: Case Report and Review of Literature by Syed Bokhari, Naeem Abbas, Manisha Singh, Richard B. Cindrich, Cosmina Zeana

“…In conclusion, E. brevis is an emerging pathogen that can cause serious health care associated infections.…”
Get full text

The Association Between Human Cytomegalovirus and Salivary Gland Cancer: An Analytical Study and Literature Review by Hagir Abd Rahman Mahmoud, Ahmed Mohamed Suleiman, Elwaleed Mohamed Elamin, Sawsan Abdel Rahim Mohammed

“… Background: Human cytomegalovirus (HCMV) is a widespread human pathogen that triggers varying clinical symptoms depending on the host’s age and immune status. …”
Get full text

Neonatal Sepsis due to Coagulase-Negative Staphylococci by Elizabeth A. Marchant, Guilaine K. Boyce, Manish Sadarangani, Pascal M. Lavoie

“…In this paper, we review the epidemiology, immunological risk factors, diagnosis, prevention, treatment, and outcomes of neonatal infection due to the predominant neonatal pathogen CoNS.…”
Get full text

Innate Immune Defenses in Human Tuberculosis: An Overview of the Interactions between Mycobacterium tuberculosis and Innate Immune Cells by Jonathan Kevin Sia, Maria Georgieva, Jyothi Rengarajan

“…TB is caused by the human pathogen, Mycobacterium tuberculosis (Mtb), which infects primarily innate immune cells patrolling the lung. …”
Get full text

THE PREVALENCE, ISOLATION, AND ANTIMICROBIAL SUSCEPTIBILITY TESTING OF ENTEROCOCCUS SPECIES FROM VARIOUS CLINICAL SAMPLES IN A TERTIARY CARE HOSPITAL by Turin Afroz

“…Background: Enterococcus is routinely considered a low-grade pathogen. The synergistic action of Enterococci with other bacteria increases the risk of infection. …”
Get full text

Stage-specific expression and divergent functions of two insulinase-like proteases associated with host infectivity in Cryptosporidium. by Yue Huang, Shifeng Pei, Xin Lv, Fuxian Yang, Xiaoqing Gong, Na Li, Yaqiong Guo, Yaoyu Feng, Lihua Xiao

“…Immunofluorescence analysis revealed that INS-19 and INS-20 are expressed at different developmental stages of the pathogen. Although knockout of either had no detectable effect on the in vitro growth of C. parvum, knockout of INS-20, deletion of its multiple domains, or mutation of the active motif in the functional domain reduced the intensity of C. parvum infection in IFN-γ knockout mice. …”
Get full text

A mathematical model for cellular immunology of tuberculosis by Eduardo Ibarguen-Mondragon, Lourdes Esteva, Leslie Chávez-Galán

“…Macrophages and T cell populations are the main responsible for fighting the pathogen. A better understanding of the interaction between Mtb, macrophages and T cells will contribute to the design of strategies to control TB. …”
Get full text

Canine circovirus: an emerging virus of dogs and wild canids by Farzad Beikpour, Arash Letafati, Zahra Ahmadi Fakhr, Nicoal Decaro, Sayed-Hamidreza Mozhgani

“…Abstract Canine Circovirus (CanineCV) is an emerging viral pathogen affecting dogs and wild canids worldwide. …”
Get full text