Rotating antibiotics selects optimally against antibiotic resistance, in theory by Robert E. Beardmore, Rafael Peña-Miller

“…The purpose of this paper is to use mathematical models to investigate the claim made in the medical literature over a decade ago that the routine rotation of antibiotics in an intensive care unit (ICU) will select against the evolution and spread of antibiotic-resistant pathogens. In contrast, previous theoretical studies addressing this question have demonstrated that routinely changing the drug of choice for a given pathogenic infection may in fact lead to a greater incidence of drug resistance in comparison to the random deployment of different drugs.…”
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Combination of metagenomic next-generation sequencing and morphology for identifying Coccidioides immitis: a case report by Hong Liu, Kaixin Zhou, Chaoran Zhong, Ming Guan

“…As coccidioidomycosis is a rare disease in China, its pathogen-specific diagnostic methods are limited. In this case, we combined two universal methods, mNGS and traditional morphological observation, to confirm the diagnosis. …”
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Prevalence of Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates in Nepal by Ranjeeta Odari, Prabin Dawadi

“…In the meta-analysis, 14 studies were combined for determining the prevalence of K. pneumoniae in total positive clinical isolates which was 16% (95% CI: 0.11–0.20), while from 12 research studies, MDR status in the pathogen was found to be 64% (95% CI, 0.53–0.74). Conclusion. …”
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A note on dynamics of an age-of-infection cholera model by Jinliang Wang, Ran Zhang, Toshikazu Kuniya

“…The model is incorporated with both the infection age of infectious individuals and biological age of pathogen in the environment. The basic reproduction number is proved to be a sharp threshold determining whether or not cholera dies out. …”
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Modeling environmental transmission of MAP infection in dairy cows by Kokum R. De Silva, Shigetoshi Eda, Suzanne Lenhart

“…To investigate the effect of persistence of this bacteria on the farm on transmission in our model, we include environmental compartments, representing the pathogen input in an explicit way. The effect of indirect transmission from the bacteria in the environment and the culling of high-shedding adults can be seen in the numerical simulations. …”
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Anthroponoses: humans infecting animals with infectious diseases by Clement Meseko, Peace Ochai, Meshach Maina

“…Also, most recently, SARS-CoV-2, the causative pathogen of COVID-19, has been retransmitted from humans to animals in a phenomenon described as “reverse zoonoses.” …”
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Potential of ethyl acetate and methanol extract from Eupatorium odoratum and Morinda citrifolia plants as Fusarium Oxysporum fungicide by Puspitasari Etika Dyah, Ma’rifah Destri Ratna, Matsjeh Sabirin

“…Fusarium oxysporum is a significat plant pathogen that affects various crops. Fusarium causing diseases and substantial agricultural losses. …”
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A Mosquito Culex cedecei Stone and Hair (Insecta: Diptera: Culicidae) by Kristin Elizabeth Sloyer, Nathan Daniel Burkett-Cadena

“…Culex cedecei is therefore considered a vector of a zoonotic pathogen that can affect human health. …”
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Metabolomic analysis of murine tissues infected with Brucella melitensis. by Bárbara Ponzilacqua-Silva, Alexis S Dadelahi, Charles R Moley, Mostafa F N Abushahba, Jerod A Skyberg

“…Brucella is a gram negative, facultative intracellular bacterial pathogen that constitutes a substantial threat to human and animal health. …”
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Development of a sustainable, green, and solar-powered filtration system for E. coli removal and greywater treatment by R. Abdallat, A.N. Bdour, A. Abu Haifa, F.F. Al-Rawash, L. Almakhadmeh, S. Hazaimeh

“…The study concludes that the solar filtration setup consistently delivers high-quality, pathogen-free greywater, meeting stringent regulatory requirements. …”
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mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against Klebsiella pneumoniae by Ting Huang, Siyou Che, Zheng Lv, Danrui Hao, Runyu Wang, Qinxuan Yi, Ling Mei, Yang Yuan, Hang Zou, Yidong Guo, Xinrong Wang, Yiwen Chu, Kelei Zhao

“…ABSTRACT Klebsiella pneumoniae is a prominent Gram-negative and encapsulated opportunistic pathogen that causes a multitude of infections such as severe respiratory and healthcare-associated infections. …”
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Small RNA CjNC110 regulates the activated methyl cycle to enable optimal chicken colonization by Campylobacter jejuni by Brandon Ruddell, Alan Hassall, Orhan Sahin, Paul J. Plummer, Qijing Zhang, Amanda J. Kreuder

“…ABSTRACT Post-transcriptional gene regulation by non-coding small RNAs (sRNAs) is critical for colonization and survival of enteric pathogens, including the zoonotic pathogen Campylobacter jejuni. …”
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Whole-genome sequencing and phylogenetic analysis of Salmonella isolated from pullets through final raw product in the processing plant of a conventional broiler complex: a longitu... by Yagya Adhikari, Matthew A. Bailey, Steven Kitchens, Pankaj Gaonkar, Luis R. Munoz, Stuart B. Price, Dianna V. Bourassa, Laura Huber, Richard J. Buhr, Kenneth S. Macklin

“…Furthermore, improper cooking or handling of contaminated raw chicken meat and meat products with Salmonella and other zoonotic pathogens can potentially cause foodborne illness in humans.…”
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Topologically constrained DNA-mediated one-pot CRISPR assay for rapid detection of viral RNA with single nucleotide resolutionResearch in context by Yanan Li, Ru Xu, Fenglei Quan, Yonghua Wu, Yige Wu, Yongyuan Zhang, Yan Liang, Zhenzhong Zhang, Hua Gao, Ruijie Deng, Kaixiang Zhang, Jinghong Li

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Epidemiology of community-acquired pneumonia among hospitalised children in Indonesia: a multicentre, prospective study by Rina Triasih, Yan Mardian, Dewi Lokida, Helmia Farida, Herman Kosasih, Adhella Menur Naysilla, Arif Budiman, Chakrawati Hayuningsih, Moh Syarofil Anam, Dwi Wastoro, Mujahidah Mujahidah, Setya Dipayana, Amalia Setyati, Abu Tholib Aman, Nurhayati Lukman, Muhammad Karyana, Ahnika Kline, Aaron Neal, Chuen-Yen Lau, Clifford Lane

“…The PCR assays on induced sputum (IS) specimens captured most of the pathogens identified in this study.Conclusions Our study found that H. influenzae non-type B and RSV were the most frequently identified pathogens causing hospitalised CAP among Indonesian children aged 2–59 months old. …”
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Computational identification of promising genetic markers associated with molecular mechanisms of reduced rice resistance to <i>Rhizoctonia solani</i> under excess nitrogen fertili... by E. A. Antropova, A. R. Volyanskaya, A. V. Adamovskaya, P. S. Demenkov, I. V. Yatsyk, T. V. Ivanisenko, Y. L. Orlov, Ch. Haoyu, M. Chen, V. A. Ivanisenko

“…Although nitrogen fertilizers increase rice yield, their excess can impair plant resistance to diseases, particularly sheath blight caused by Rhizoctonia solani. This pathogen can destroy up to 50 % of the crop, but the mechanisms underlying reduced resistance under excess nitrogen remain poorly understood. …”
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Identification of an immunological signature of long COVID syndrome by Gisella Guerrera, Manolo Sambucci, Eleonora Timperi, Mario Picozza, Andrea Misiti, Andrea Misiti, Roberta Placido, Silvia Corbisiero, Silvia D’Orso, Andrea Termine, Carlo Fabrizio, Francesca Gargano, Sharon Eleuteri, Luisa Marchioni, Veronica Bordoni, Luigi Coppola, Marco Iannetta, Chiara Agrati, Giovanna Borsellino, Luca Battistini

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Seroprevalence of Borrelia burgdorferi sensu lato antibodies in English adult blood donors: A nationwide cross-sectional study, 2021–2022 by Eilish Hart, John Tulloch, Daniel Bailey, Tim Brooks, Heli Harvala, Peter Simmonds, Roberto Vivancos, Neil French, Amanda Semper

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Studying a collection of common-wheat varieties for leaf rust resistance, crop yield and grain quality in the environmental conditions of Novosibirsk region by L. P. Sochalova, V. A. Aparina, N. I. Boyko, E. V. Zuev, E. V. Morozova, E. V. Musinov, N. A. Vinichenko, I. N. Leonova, V. V. Piskarev

“…The study of leaf rust resistance in 49 common wheat varieties was carried out in the field against the natural pathogen background and under laboratory conditions using single-pustule isolates with virulence to Lr9 and Lr24. …”
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The increasing burden of group B Streptococcus from 2013 to 2023: a retrospective cohort study in Beijing, China by Yingxing Li, Wenhang Yang, Yi Li, Kexin Hua, Ying Zhao, Taie Wang, Lingli Liu, Yali Liu, Yao Wang, Wenjing Liu, Li Zhang, Renyuan Zhu, Shuying Yu, Hongli Sun, Hongtao Dou, Qiwen Yang, Yingchun Xu, Lina Guo

“…ABSTRACT Group B Streptococcus (GBS) is a leading pathogen responsible for fatal infections in newborns primarily due to vertical transmission from colonized mothers. …”
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