Application of metagenomic next-generation sequencing in the diagnosis of post-stroke infections: a case series study using multiple sample types by Xiaopu Chen, Yong Liang, Wei Yang, Wenzhen He, Zhiqiang Xing, Shunxian Li, Shaoyu Cai, Jiping Fu, Xiaotang Peng, Manli Chen, Jiaming Wu

“…BackgroundMetagenomic high-throughput sequencing (mNGS) represents a powerful tool for detecting nucleic acids from various pathogens, such as bacteria, fungi, viruses and parasites, in clinical samples. …”
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The mcpC mutant of Salmonella enteritidis exhibits attenuation and confers both immunogenicity and protective efficacy in mice by Lu Zhang, Li Chen, Xuqiang Zhang, Yang Li, Qingfeng Zheng, Yun Li, Ning Li, Qiumei Shi, Yanying Zhang, Tonglei Wu

“…This presents a significant threat to public health. To eliminate this pathogen, the development of novel vaccines targeting SE is imperative. …”
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Comparison of the Impact of tNGS with mNGS on Antimicrobial Management in Patients with LRTIs: A Multicenter Retrospective Cohort Study by Li D, Li Q, Huang Z, Wu W, Fan X, Liu J, Li R, Zhang Q, Su X

“…The distribution of detected pathogens was similar between tNGS and mNGS, with bacteria being the predominant microorganisms. …”
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Akkermansia muciniphila identified as key strain to alleviate gut barrier injury through Wnt signaling pathway by Xin Ma, Meng Li, Yuanyuan Zhang, Tingting Xu, Xinchen Zhou, Mengqi Qian, Zhiren Yang, Xinyan Han

“…As the largest mucosal surface, the gut has built a physical, chemical, microbial, and immune barrier to protect the body against pathogen invasion. The disturbance of gut microbiota aggravates pathogenic bacteria invasion and gut barrier injury. …”
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Deep mutational scanning of the Trypanosoma brucei developmental regulator RBP6 reveals an essential disordered region influenced by positive residues by Saúl Rojas-Sánchez, Nikolay G. Kolev, Christian Tschudi

“…Abstract To regain infectivity, Trypanosoma brucei, the pathogen causing Human and Animal African trypanosomiasis, undergoes a complex developmental program within the tsetse fly known as metacyclogenesis. …”
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Investigation of virulence factors in resistance and sensitive pseudomonas aeruginosa clinical isolates by Zeinab Waheed kadim, Hala Mouayed Radif

“… The pathogen "Pseudomonas aeruginosa" is extremely hazardous for people with weak immune systems because it has several virulence factors and can resist antibiotics. …”
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First report of Pseudomonas marginalis causing tuber soft rot of potato in Iran by Simin Ghasemi, Pejman Khodaygan, Srđan G Aćimović, Esmaeil Basavand

“…Bacteria, which appeared as white to creamy colonies, were isolated from diseased tissues and shown to be pathogenic on potato tubers after inoculation and re-isolation of the isolates. …”
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Current status of recombinant duck enteritis virus vector vaccine research by Wen-Feng Jia, An-Ping Wang, Zhi Wu, Xin-Nuo Lei, Yu-Ting Cheng, Shan-Yuan Zhu

“…Duck enteritis virus (DEV), the pathogen of duck viral enteritis, belongs to the α-herpesvirus subfamily. …”
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The Management of Inflatable Penile Prosthesis Erosion and Infection following Iatrogenic Aspiration by Ali Baydoun, Alexander Benben, Matthew Skalak, Jordan Bilbrew, Mazen Abdelhady

“…Intraoperative cultures identified Escherichia cloacae as the causative pathogen. This case highlights the importance of thorough chart review to identify patients with IPPs before aspiration procedures and emphasizes the need for healthcare provider education regarding potential complications in this patient population. …”
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Modulation by NPY/NPF-like receptor underlies experience-dependent, sexually dimorphic learning by Sonu Peedikayil-Kurien, Rizwanul Haque, Asaf Gat, Meital Oren-Suissa

“…Here, we reveal sexual dimorphism in learning: C. elegans males do not learn to avoid the pathogenic bacteria PA14 as efficiently and rapidly as hermaphrodites. …”
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N-Acetylglucosamine Functions in Cell Signaling by James B. Konopka

“…For example, GlcNAc stimulates the human fungal pathogen Candida albicans to undergo changes in morphogenesis and expression of virulence genes. …”
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Bacteriophage Administration Reduces the Concentration of Listeria monocytogenes in the Gastrointestinal Tract and Its Translocation to Spleen and Liver in Experimentally Infected... by Volker Mai, Maria Ukhanova, Lee Visone, Tamar Abuladze, Alexander Sulakvelidze

“…To investigate the efficacy of phage supplementation in reducing pathogen numbers, mice were treated via oral gavage with a Listeria monocytogenes phage preparation (designated ListShield) before being orally infected with L. monocytogenes. …”
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Preventing Foodborne Illness: E. coli O157:H7 by Keith R. Schneider, Renée Goodrich Schneider, Ploy Kurdmongkoltham, Bruna Bertoldi

“… This seven-page fact sheet discusses the common foodborne pathogen E. coli O157:H7, especially as it concerns food handlers, processors and retailers. …”
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First autochthonous case of Opisthorchis felineus in Austria by Lisa-Maria Kulmer, Maria Sophia Unterköfler, Yasamin Vali, Ilse Schwendenwein, Nicole Luckschander-Zeller

“…Abstract Background Opisthorchis felineus is a feline pathogen with zoonotic potential that can be a causative agent of human opisthorchiasis and cholangiocarcinoma. …”
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Molecular Detection and Characterization of Pasteurella multocida Infecting Camels in Marsabit and Turkana Counties, Kenya by Justus K. Kasivalu, George I. Omwenga, Gabriel O. Aboge

“…Pasteurella multocida infection is common in Kenya though there is little knowledge of the genetic diversity of the pathogen. P. multocida is part of the normal flora in the respiratory tract of camels, but it becomes pathogenic when the resistance of the camel body is diminished by bad ecological conditions. …”
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Suppurative Mediastinitis Secondary to Burkholderia Cepacia in a Patient with Cystic Fibrosis by Ronald B George, Yannick Cartier, Alan G Casson, Paul Hernandez

“…Burkholderia cepacia is an important opportunistic pathogen among patients with cystic fibrosis (CF); it is associated with deterioration of lung function, poor outcome following lung transplantation and increased mortality. …”
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Roles of Inflammasomes in Inflammatory Kidney Diseases by Jinjin Fan, Kaifeng Xie, Liqin Wang, Nuoyan Zheng, Xueqing Yu

“…The immune system has a central role in eliminating detrimental factors, by frequently launching inflammatory responses towards pathogen infection and inner danger signal outbreak. …”
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Streptococcus intermedius Bacteremia and Liver Abscess following a Routine Dental Cleaning by Lachara V. Livingston, Elimarys Perez-Colon

“…In fact, the development of liver abscesses secondary to dental procedures is very rare in general, and there are only a few case reports in the literature describing this in relation to any pathogen. We present a rare case of S. intermedius bacteremia and liver abscess following a dental cleaning. …”
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Effect of Noradrenaline on the Virulence Properties of Campylobacter Species by Sree V. Aroori, Tristan A. Cogan, Tom J. Humphrey

“…Several studies have shown that it stimulated growth and increased the pathogenicity of organisms including E. coli and Campylobacter jejuni. …”
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A systematic review on malaria and Tuberculosis (TB) vaccine challenges in sub-Saharan African clinical trials. by Maonezi Abas Hamisi, Nur Ain Mohd Asri, Aini Syahida Mat Yassim, Rapeah Suppian

“…<h4>Conclusion</h4>Factors such as population characteristics, pathogen genetic diversity, vaccine nature, strategy, and formulation were associated with slow progress of the malaria and TB vaccine candidates in sub-Saharan African clinical trials.…”
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