HMGB1 Promotes Systemic Lupus Erythematosus by Enhancing Macrophage Inflammatory Response by Mudan Lu, Shanshan Yu, Wei Xu, Bo Gao, Sidong Xiong

“…HMGB1, which may act as a proinflammatory mediator, has been proposed to contribute to the pathogenesis of multiple chronic inflammatory and autoimmune diseases including systemic lupus erythematosus (SLE); however, the precise mechanism of HMGB1 in the pathogenic process of SLE remains obscure. Method. The expression of HMGB1 was measured by ELISA and western blot. …”
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Modeling the Distribution of Dominant Hard Ticks in Southeastern Coastal Areas of the Caspian Sea by Sedighe Nabian, Elahe Ebrahimzadeh, Abbas Farahi, Ahmad Ali Hanafi-Bojd

“… Background: Ticks are hematophagous arthropods that have direct and indirect effects on hosts, including the trans­mission of pathogens. An environmental suitability study of some vector species of hard ticks was conducted using the MaxEnt model in the south-eastern region of the Caspian Sea in Iran. …”
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Intestinal Mucosal Barrier Is Injured by BMP2/4 via Activation of NF-κB Signals after Ischemic Reperfusion by Kang Chen, Wei Xie, Binyu Luo, Weidong Xiao, Daniel H. Teitelbaum, Hua Yang, Kebin Zhang, Chaojun Zhang

“…On the basis of these data, we conclude that BMP2/4 may act as the pathogenic basis for intestinal mucosal barrier dysfunction when the intestines suffer an I/R injury. …”
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Spent Coffee Ground and Its Derivatives as Soil Amendments—Impact on Soil Health and Plant Production by Yi Hu, Juan Li, Yiping Wu, Dongdong Zhang, Zhiyong Qi, Rui Yang

“…SCG and its derivatives may be used as biocontrol agents for weeds, soil-borne pathogens, and pests. Novel bio-organic fertilizers based on SCG have also been developed. …”
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Whole-Genome Expression Analysis and Signal Pathway Screening of Synovium-Derived Mesenchymal Stromal Cells in Rheumatoid Arthritis by Jingyi Hou, Yi Ouyang, Haiquan Deng, Zhong Chen, Bin Song, Zhongyu Xie, Peng Wang, Jinteng Li, Weiping Li, Rui Yang

“…Our study found that differentially expressed genes in the MAPK signaling, rheumatoid arthritis, and p53 signaling pathways may help to explain the pathogenic mechanism of RA and lead to therapeutic RA SMSC applications.…”
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Physiological and Antagonistic Properties of Pichia kluyveri for Curative and Preventive Treatments Against Post-Harvest Fruit Fungi by Maxwell Mewa Ngongang, Heinrich Wilbur Du Plessis, Chidi Silas Boredi, Ucrecia Faith Hutchinson, Karabo Seteno Obed Ntwampe, Vincent Ifeanyi Okudoh, Neil Paul Jolly

“…Similarly, preventive application on grapes was also effective against the fungal pathogens studied. In general, the antagonistic responses were both fungus- and treatment- (curative and preventive) dependent. …”
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Stimulation of MMP-1 and CCL2 by NAMPT in PDL Cells by Marjan Nokhbehsaim, Sigrun Eick, Andressa Vilas Boas Nogueira, Per Hoffmann, Stefan Herms, Holger Fröhlich, Søren Jepsen, Andreas Jäger, Joni Augusto Cirelli, James Deschner

“…Periodontitis is an inflammatory disease caused by pathogenic microorganisms and characterized by the destruction of the periodontium. …”
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A cGAMP‐Containing Hydrogel for Prolonged SARS‐CoV‐2 Receptor‐Binding Domain Subunit Vaccine Exposure Induces a Broad and Potent Humoral Response by Volker Böhnert, Emily C. Gale, Lauren J. Lahey, Jerry Yan, Abigail E. Powell, Ben S. Ou, Jacqueline A. Carozza, Lingyin Li, Eric A. Appel

“…The cGAMP‐adjuvanted hydrogel platform can be further explored for the delivery of other antigens to enhance immunity against a broad range of pathogens.…”
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Faecalibacterium prausnitzii: A Next-Generation Probiotic in Gut Disease Improvement by Xiaoya He, Shuyang Zhao, Yan Li

“…The researchers are paying more attention to the role of gut commensal bacteria in health development beyond the classical pathogens. It has been widely demonstrated that dysbiosis, which means the alternations of the gut microbial structure, is closely associated with development of intestinal chronic inflammation-related diseases such as inflammatory bowel disease (IBD), and even infectious diseases including bacterial and viral infection. …”
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Antagonistic Activity of Extremophilic Bacteria Against Phytopathogens in Agricultural Crops by Lyudmila K. Asyakina, Yuliya R. Serazetdinova, Anna S. Frolova, Natalya V. Fotina, Olga A. Neverova, Andrey N. Petrov

“…The resulting consortium can be used as a biopesticide since it is highly effective in protecting wheat from Alternaria and Fusarium pathogens.…”
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New Insights in the Pathogenesis of HPV Infection and the Associated Carcinogenic Processes: The Role of Chronic Inflammation and Oxidative Stress by Simona Roxana Georgescu, Cristina Iulia Mitran, Madalina Irina Mitran, Constantin Caruntu, Maria Isabela Sarbu, Clara Matei, Ilinca Nicolae, Sandra Milena Tocut, Mircea Ioan Popa, Mircea Tampa

“…The host’s immunity plays a central role in the course of the infection; therefore, it may not be clinically manifest or may produce various benign or malignant lesions. The pathogenic mechanisms are complex and incompletely elucidated. …”
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Gain-of-Function Mutations in STAT1: A Recently Defined Cause for Chronic Mucocutaneous Candidiasis Disease Mimicking Combined Immunodeficiencies by Sanem Eren Akarcan, Ezgi Ulusoy Severcan, Neslihan Edeer Karaca, Esra Isik, Guzide Aksu, Mélanie Migaud, Ferda Evin Gurkan, Elif Azarsiz, Anne Puel, Jean-Laurent Casanova, Necil Kutukculer

“…Chronic-recurrent infections with different pathogens leading to significant morbidity suggested combined immunodeficiency, CMC, or Mendelian susceptibility to mycobacterial diseases. …”
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Genomic Landscape Reveals Chromosomally-Mediated Antimicrobial Resistome and Virulome of a High-Risk International Clone II Acinetobacter baumannii AB073 from Thailand by Rattiya Cheewapat, Jadsadaporn Redkimned, Sirikran Lekuthai, Thawatchai Kitti, Kannipa Tasanapak, Aunchalee Thanwisai, Sutthirat Sitthisak, Thanet Sornda, Hathaichanok Impheng, Sudarat Onsurathum, Udomluk Leungtongkam, Supaporn Lamlertthon, Siriwat Kucharoenphaibul, Jintana Wongwigkarn, Pantira Singkum, Pattrarat Chanchaithong, Rapee Thummeepak

“…In addition, the genomic epidemiological study showed that AB073-like strains were successful pathogens widespread in various geographic locations and clinical sources. …”
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Prenatal diagnosis of mucopolysaccharidosis type I on hepatosplenomegaly and coarse features: a case-report by Maxime Agranier, Florence Demurger, Christele Dubourg, Jerome Fromageot, Anne-Sophie Cabaret Dufour, Erika Launay, Magalie Gournay, Charles Lefèvre, Roseline Froissart, Magali Pettazzoni, Paul Rollier

“…Whole exome sequencing after amniocentesis identified two likely pathogenic IDUA gene variants (in trans), raising suspicion of a diagnosis of MPS I. …”
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Concomitant of Pulmonary Hydatid Cyst and Aspergilloma: A Rare Coinfection by Zahra Zareshahrabadi, Bahador Sarkari, Nadereh Shamsolvaezin, Bizhan Ziaian, Alireza Tootoonchi, Reza Shahriarirad, Kamiar Zomorodian

“…Further attention is recommended to control fungal pathogens during pulmonary hydatidosis. The coexistence of aspergilloma should always be kept in mind for the better management of CE.…”
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Complete Genome Sequence Analysis of Bacillus subtilis MC4-2 Strain That against Tobacco Black Shank Disease by Chunlan Shi, Shuquan Zeng, Xi Gao, Mehboob Hussain, Mingchuan He, Xurong Niu, Congcong Wei, Rui Yang, Mingxian Lan, Yonghui Xie, Zhijiang Wang, Guoxing Wu, Ping Tang

“…The MC4-2 bacterium strain was isolated and purified from the Periplaneta americana intestine as a biocontrol agent with good antagonistic effect against the pathogens of a soil-borne disease called tobacco black shank. …”
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Contribution of Phosphorylation Modification to Stability and Antibacterial Activity of Egg White Protein Nanogels Loaded with Cinnamon Bark Essential Oil by Sheng-Qi Rao, Xin-Ru Gao, Hui Liu, Zhi-Rong Wang, Zhen-Quan Yang

“…In addition, the results of the antibacterial experiments on <i>Escherichia coli</i>, <i>Staphylococcus aureus</i>, and <i>Listeria monocytogenes</i> showed that the MIC values of P-EWP-CBEO nanogels were two times lower than those of EWP-CBEO nanogels and could completely inhibit the growth of pathogenic bacteria within 108 h. Hence, we have suggested that P-EWP-CBEO nanogels are successfully fabricated with improved physicochemical properties as novel potential natural preservatives in the food industry.…”
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Modeling the Combined Effects of Temperature, pH, and Sodium Chloride and Sodium Lactate Concentrations on the Growth Rate of Lactobacillus plantarum ATCC 8014 by Francieli Dalcanton, Elena Carrasco, Fernando Pérez-Rodríguez, Guiomar Denisse Posada-Izquierdo, Gláucia Maria Falcão de Aragão, Rosa María García-Gimeno

“…Lactic acid bacteria are able to synthetize compounds with antimicrobial activity against pathogenic and spoilage flora. Among them, Lactobacillus plantarum ATCC 8014 has exhibited this capacity, and further studies reveal that the microorganism is able to produce bacteriocins. …”
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Molecular Detection of FIPV among Imported Felines through Soekarno Hatta Airport, Indonesia by Fidyah Fitrawati, Suwarno, Ira Sari Yudaniayanti, Jola Rahmahani, Muchammad Yunus, Soeharsono, Desniwaty Karo-karo, Haeriah

“…Type I is a highly pathogenic strain, feline infectious peritonitis virus (FIPV). …”
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Myoclonic status epilepticus with dystonia-like symptoms in patients with dementia: Report of two cases by Rosario V. Rossi, Rosanna Melis, Noemi Murdeu, Sara Lizzos, Maria Luigia Piras, Loretta Racis, Silvia Serusi, Maria Valeria Saddi

“…A time-locked relationship between the frontocentral EEG activity and the EMG myoclonic potentials demonstrated the cortical origin of myoclonus and therefore the epileptic nature of the disorder, whereas the oromandibular and cervical dystonic-like postures suggested the pathogenic involvement of subcortical structures. The intravenous administration of diazepam suppressed the clinical symptoms and the EEG–EMG correlate of myoclonus. …”
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