Epilepsy and preventive antiepileptic treatment in tuberous sclerosis complex. Literature review by I. Kasiulevičiūtė

“… Tuberous sclerosis complex (TSC) is a rare genetic disorder characterized by the presence of benign tumors in many organs. The pathogenic mutation is found in either the TSC1 or TSC2 tumor suppressor genes. …”
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An Advanced Understanding of Uterine Microbial Ecology Associated with Metritis in Dairy Cows by Soo Jin Jeon, Klibs N. Galvão

“…According to culture-dependent studies, uterine pathogens include Escherichia coli, Trueperella pyogenes, Fusobacterium necrophorum, and Prevotella melaninogenica. …”
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Epidemiology of Enterocytozoon bieneusi Infection in Humans by Olga Matos, Maria Luisa Lobo, Lihua Xiao

“…Studies on the prevalence of these emerging microsporidian pathogens in humans, in developed and developing countries, the different clinical spectra of E. bieneusi intestinal infection in children, in different settings, and the risk factors associated with E. bieneusi infection have been reviewed. …”
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Guide to Using Rhizomal Perennial Peanut in the Urban Landscape by Robert E. Rouse, Elan M. Miavitz, Fritz M. Roka

“… Perennial peanut has recently shown promise as an ornamental groundcover due to its high resistance to drought, nematodes, and pathogens and its minimal fertilizer needs. This translates into savings in water, energy, dollars, and reduced impacts to the environment. …”
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Invasive Microascus trigonosporus Species Complex Pulmonary Infection in a Lung Transplant Recipient by Kelly E. Schoeppler, Martin R. Zamora, Noelle M. Northcutt, Gerard R. Barber, Gayle O’Malley-Schroeder, Dennis M. Lyu

“…However, this prophylaxis is not universally effective and may contribute to the selection of emerging, resistant pathogens. Here we present a rare case of invasive infection caused by Microascus trigonosporus species complex in a human, which developed during voriconazole prophylaxis in a lung transplant recipient. …”
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Phylobook: a tool for display, clade annotation and extraction of sequences from molecular phylogenies by Jeffrey C Furlong, Peter D Darley, Wenjie Deng, James I Mullins, Roger E Bumgarner

“…As the volume of sequence data from variable pathogens increases, means of analyzing, annotating and extracting specific taxa for study becomes more difficult. …”
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Thyroid Storm Triggered by Rotavirus Infection in a 10-Year-Old Girl by Masazumi Miyahara, Shizuka Otsuki

“…Our case highlights the need for further investigation into the potential triggering pathogens in patients with TS to better clarify details regarding the patient’s status or disease pathogenesis.…”
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Hypoxic-Ischemic Injury in the Developing Brain: The Role of Reactive Oxygen Species Originating in Mitochondria by Vadim S. Ten, Anatoly Starkov

“…This paper focuses on current data that support a pathogenic role of ROS originating from mitochondrial respiratory chain in the promotion of secondary energy failure and proposes potential therapeutic strategy against reperfusion-driven oxidative stress following hypoxia-ischemia-reperfusion injury of the developing brain.…”
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PDE12 mediated pruning of the poly-A tail of mitochondrial DNA-encoded tRNAs is essential for survival by Chenxiao Yu, Marco Tigano, Erin L Seifert

“…A new study by Van Haute and colleagues (Van Haute et al, 2024) describes the first pathogenic variants in the human PDE12 gene. The 3 missense mutations that were identified each carry severe phenotypic consequences that correlate with the presence or not of residual PDE12 protein, show cell-type-specific adaptive responses, and specificity in the mtDNA-encoded electron transport chain subunits that are most affected. …”
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Role of Transient Receptor Potential Canonical Channel 6 (TRPC6) in Diabetic Kidney Disease by Regulating Podocyte Actin Cytoskeleton Rearrangement by Qian Wang, Xuefei Tian, Yuyang Wang, Yan Wang, Jialin Li, Tingting Zhao, Ping Li

“…Actin cytoskeleton rearrangement in podocyte induced by multiple pathogenic factors is believed to be the key process resulting in glomerular injury. …”
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Molecular Detection of Porcine Torovirus in Piglets with Diarrhea in Southwest China by Yuancheng Zhou, Lei Chen, Ling Zhu, Zhiwen Xu

“…Statistical analysis of the PToV positive rate as well as a survey for other enteric pathogens in diarrheic pigs suggests that PToV may play a role as a causative agent of severe diarrhea in piglets.…”
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Anti-N-Methyl-D-aspartate Receptor Encephalitis: A Severe, Potentially Reversible Autoimmune Encephalitis by Cai-yun Liu, Jie Zhu, Xiang-Yu Zheng, Chi Ma, Xu Wang

“…Anti-NMDAR antibodies in cerebrospinal fluid (CSF) and serum are characteristic features of the disease, thereby suggesting a pathogenic role in the disease. Here, we summarize recent studies that have clearly documented that both clinical manifestations and the antibodies may contribute to early diagnosis and multidisciplinary care. …”
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Altered Immunoregulation in Rheumatoid Arthritis: The Role of Regulatory T Cells and Proinflammatory Th17 Cells and Therapeutic Implications by Alessia Alunno, Mirko Manetti, Sara Caterbi, Lidia Ibba-Manneschi, Onelia Bistoni, Elena Bartoloni, Valentina Valentini, Riccardo Terenzi, Roberto Gerli

“…In recent years several studies investigated the role of T lymphocyte subpopulations in the pathogenesis of rheumatoid arthritis (RA). Pathogenic Th17 cells mediate pannus growth, osteoclastogenesis, and synovial neoangiogenesis; hence they are key players in the development of the disease. …”
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A human-induced pluripotent stem cell (iPSC) line (SMUSHi006-A) from an ALS patient carrying a mutation c.1126C > T in the FUS gene by Chunyan Huang, Liying Qiu, Wenyan Zhou, Congwen Shao, Xichun Wang, Qiwen Zhang, Weilin Chen, Min Xiong, Min Huang, Mei Tang, Liangyu Zou, Xueqing Xu

“…The objective of this study is to create another iPS cell line featuring the pathogenic c.1126C > T mutation in the FUS gene. This research aims not only to establish a disease model for ALS linked to FUS mutations but also to pave the way for potential therapeutic interventions.…”
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Florida Beekeeping Management Calendar by James D. Ellis, Mary C. Bammer, William H. Kern Jr.

“…It is specific to region (north, central, and south Florida) and month and includes recommendations for major management considerations like when to treat for parasites or pathogens and when to feed colonies or harvest honey. …”
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Virological Aspects of COVID-19 in Patients with Hematological Malignancies: Duration of Viral Shedding and Genetic Analysis by Asma Themlaoui, Massimo Ancora, Kais Ghedira, Yosra Mhalla, Manel Hamdoun, Maroua Bahri, Lamia Aissaoui, Raihane Ben Lakhal, Adriano Di Pasquale, Cesare Camma, Olfa Bahri

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Septoriablotch epidemic process on spring wheat varieties by E. Yu. Toropova, O. A. Kazakova, V. V. Piskarev

“…In the control systems of Septoriablotch the main ecologically safe element is resistant  varieties, which are designed to slow down the pathogens reproduction rate and slow down or stop the development of the epiphytotic process. …”
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In ovo delivery of carvacrol triggers expression of chemotactic factors, antimicrobial peptides and pro-inflammatory pathways in the yolk sac of broiler chicken embryos by Mila M. Y. Meijer, Henry van den Brand, Shahram Niknafs, Eugeni Roura

“…Conclusion In conclusion, these findings suggest that in ovo delivery of carvacrol has the potential to enhance anti-pathogenic and pro-inflammatory responses in the yolk sac via upregulation of antimicrobial peptides, and NOD-like receptor pathways.…”
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Improving prenatal diagnosis with combined karyotyping, CNV-seq and QF-PCR: a comprehensive analysis of chromosomal abnormalities in high-risk pregnancies by Jia-pei Liu, Shan-Bing Wang, Li Luo, Ya-mei Guo

“…CNV-seq uniquely identified additional pathogenic copy number variations in 2.1% of cases and variants of uncertain significance (VUS) in 3.2% of cases, both undetectable by conventional karyotyping. …”
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Surveillance of SARS-CoV-2 variants in Henan, China from 2023 to 2024 by Yun Song, Bicong Wu, Hongxia Ma, Yafei Li, Su Yan, Jingjing Pan, Haifeng Wang, Ying Ye, Xueyong Huang, Wanshen Guo

“…Both XBB and BA.2.86 variants exhibit lower pathogenicity. This study provides vital scientific evidence on the epidemiological features, clinical manifestations, and control strategies of SARS-CoV-2 variants. …”
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