Role of Pore-Forming Toxins in Neonatal Sepsis by Andreas F.-P. Sonnen, Philipp Henneke

“…Protein toxins are important virulence factors contributing to neonatal sepsis. The major pathogens of neonatal sepsis, group B Streptococci, Escherichia coli, Listeria monocytogenes, and Staphylococcus aureus, secrete toxins of different molecular nature, which are key for defining the disease. …”
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Overview of Mink Immunity and Resistance to Pseudomonas aeruginosa by Jiangsong Bai, Xiao Wang, Zihui Zhang, Pengjing Lian, Jian Qiao

“…Pseudomonas aeruginosa is one of the most host-susceptible pathogenic bacteria to cause acute and chronic infections in humans and animals. …”
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Quantitative Evaluation of Bacteria Adherent and in Biofilm on Single-Wall Carbon Nanotube-Coated Surfaces by Fabrizio Pantanella, Francesca Berlutti, Daniele Passeri, Daniela Sordi, Alessandra Frioni, Tiziana Natalizi, Maria Letizia Terranova, Marco Rossi, Piera Valenti

“…However, data about the antibacterial properties of nano-structured surfaces are fragmentary and controversial, and, in particular, the susceptibility of nano-structured materials to colonization and biofilm formation by bacterial pathogens has not been yet thoroughly considered. Here, the ability of the pathogenic Streptococcus mutans and Pseudomonas aeruginosa to adhere and form biofilm on surfaces coated with single-wall carbon nanotubes (SWCNTs) was analyzed. …”
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A review of COVID-19-related thrombosis and anticoagulation strategies specific to the Asian population by Kai Chin Poh, Victoria Yu Jia Tay, Sarah Huixin Lin, Huei Leng Chee, Suhitharan Thangavelautham

“…It is increasingly being recognised that the pathogenicity of COVID-19 extends beyond the respiratory system. …”
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Repurposing of Drugs for Antibacterial Activities on Selected ESKAPE Bacteria Staphylococcus aureus and Pseudomonas aeruginosa by Bridget Kamurai, Molly Mombeshora, Stanley Mukanganyama

“…Increasing cases of multidrug-resistant pathogens have evolved into a global health crisis. …”
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Bacterial aetiology of chronic otitis media with effusion in children - risk factors by Izabela Korona-Glowniak, Agata Wisniewska, Marek Juda, Karolina Kielbik, Grazyna Niedzielska, Anna Malm

“…However, one third of MEF samples had multiple bacterial pathogens.…”
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Immunopathology of Airway Surface Liquid Dehydration Disease by Brandon W. Lewis, Sonika Patial, Yogesh Saini

“…In particular, the mucociliary escalator provides an effective mechanism for the continuous removal of inhaled insults including pathogens. Defects in the functioning of the mucociliary escalator compromise the mucociliary clearance (MCC) of inhaled pathogens, which favors microbial lung infection. …”
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Functional analysis of a novel homozygous missense IVD gene variant: a case report with dual genetic diagnoses by Yuying Zhu, Ke Wu, Hanying Wen

“…BackgroundGenomic or exome sequencing is beneficial for identifying more than one pathogenic variation causing blended atypical and/or severe phenotypes. …”
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DETECTION OF PORCINE CIRCOVIRUS TYPE 3 IN RUSSIAN PIG HOLDINGS by M. V. Biryuchenkova, A. M. Timina, A. V. Shcherbakov

“…Further studies are required for identification of actual PCV-3 pathogenicity and its prevalence in the territory of the Russian Federation.…”
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Assessing the Prevalence of Viral and Virus-Like Diseases in Citrus Orchards of Northeast Morocco: A Contribution to Orchard Health by Abdelhak Khallou, Zineb Belabess, Yassine Boualam, Safae Mohsini, Rachid Lahlali

“…However, this agricultural heritage faces significant threats from various pathogens, transmitted either naturally or mechanically, among which viruses and virus-like organisms are predominant. …”
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Antimicrobial Potential of Streptomyces spp. Isolated from the Rift Valley Regions of Ethiopia by Firew Elias, Sudhamani Muddada, Diriba Muleta, Belachew Tefera

“…Among the isolates, 172 (69.1%) showed antimicrobial activities against tested pathogens. The inhibition zone of the isolates ranged from 5 ± 0.31 to >40 mm during primary screening. …”
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Identification of novel RIPK4 variants in a Chinese patient with Arthrogryposis Multiplex Congenita (AMC) by Yi-Lei Lu, Meng-wei Liu, Jie-Yuan Jin, Ding Pan

“…Whole-exome sequencing (WES) was employed to determine the genetic etiologies of the patient’s disease. The pathogenic mechanisms of the identified variations were analyzed using protein tolerance profiling and modeling. …”
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Correlation between uterine microbiota and pregnancy outcomes of embryo transfer in overweight and obese women by Ying Yan, Ying Li, Lingling Wu, Yuxuan Zhang, Hong Guo, Yazhong Ji

“…In individuals with higher BMI, pathogenic bacteria are more likely to impair endometrial receptivity, ultimately leading to adverse pregnancy outcomes. …”
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Genome-wide quantification of polycistronic transcription in Leishmania major by Janne Grünebast, Stephan Lorenzen, Joachim Clos

“…ABSTRACT Leishmania major is a human-pathogenic, obligate parasite and the etiological agent of the most prevalent, cutaneous form of leishmaniasis, which is an important neglected, tropical disease with ~1.2 million new infections per year. …”
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Genomic insights into the probiotic potential and genes linked to gallic acid metabolism in Pediococcus pentosaceus MBBL6 isolated from healthy cow milk. by Md Morshedur Rahman, Naim Siddique, Soharth Hasnat, Md Tanvir Rahman, Mustafizur Rahman, Munirul Alam, Ziban Chandra Das, Tofazzal Islam, M Nazmul Hoque

“…Furthermore, MBBL6 exhibited susceptibility to a wide range of antibiotics in-vitro, and effectively suppressed mastitis pathogens in an in-vivo mouse mastitis model trial. …”
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Host Defence to Pulmonary Mycosis by Christopher H Mody, Peter W Warren

“…OBJECTIVE: To provide a basic understanding of the mechanisms of host defense to pathogenic fungi. This will help physicians understand why some patients are predisposed to fungal infections and update basic scientists on how microbial immunology applies to fungal disease.…”
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Systematic literature review on Calcium Pyrophosphate Deposition (CPPD) nomenclature: condition elements and clinical states— A Gout, Hyperuricaemia and Crystal-Associated Disease... by Georgios Filippou, Antonella Adinolfi, Emilio Filippucci, Nicola Dalbeth, Robert Terkeltaub, Tristan Pascart, Edoardo Cipolletta, Silvia Sirotti, Charlotte Jauffret, Sara Tedeschi, Daniele Cirillo, Luca Ingrao, Alessandro Lucia

“…Eight reviewers independently and manually extracted labels related to CPPD concepts, according to an a priori list generated by the authors: pathogenic conditions and pathogenic crystal labels, elementary imaging condition elements and asymptomatic and symptomatic condition states. …”
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Isolation and Characterization of Colistin-Resistant <i>Enterobacteriaceae</i> from Foods in Two Italian Regions in the South of Italy by Rosa Fraccalvieri, Angelica Bianco, Laura Maria Difato, Loredana Capozzi, Laura Del Sambro, Stefano Castellana, Adelia Donatiello, Luigina Serrecchia, Lorenzo Pace, Donatella Farina, Domenico Galante, Marta Caruso, Maria Tempesta, Antonio Parisi

“…Virulence gene analysis showed that <i>E. coli</i> and other isolates carried genes linked to pathogenicity, increasing the potential risk to public health. …”
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Auditory Phenotype of a Novel Missense Variant in the CEACAM16 Gene in a Large Russian Family With Autosomal Dominant Nonsyndromic Hearing Loss by Tatiana G. Markova, Natalia N. Alekseeva, Oxana P. Ryzhkova, Olga L. Shatokhina, Anna A. Orlova, Viktoriia V. Zabnenkova, Olga S. Groznova, Olesya V. Sagaydak, Svetlana S. Chibisova, Alexander V. Polyakov, George A. Tavartkiladze

“…Currently, 8 pathogenic variants in this gene have been described. …”
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Clinical and molecular analyses of isolated central congenital hypothyroidism based on a survey conducted in Japan by Nao Shibata, Chikahiko Numakura, Takashi Hamajima, Kenichi Miyako, Ikuma Fujiwara, Jun Mori, Akihiko Saitoh, Keisuke Nagasaki

“…The results revealed IGSF1 and TBL1X pathogenic variants in nine and one patient, respectively. …”
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