SHASI-ML: a machine learning-based approach for immunogenicity prediction in Salmonella vaccine development by Ottavia Spiga, Ottavia Spiga, Ottavia Spiga, Anna Visibelli, Francesco Pettini, Bianca Roncaglia, Annalisa Santucci, Annalisa Santucci, Annalisa Santucci

“…IntroductionAccurate prediction of immunogenic proteins is crucial for vaccine development and understanding host-pathogen interactions in bacterial diseases, particularly for Salmonella infections which remain a significant global health challenge.MethodsWe developed SHASI-ML, a machine learning-based framework for predicting immunogenic proteins in Salmonella species. …”
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Identification and characterization of the functional tetrameric UDP-glucose pyrophosphorylase from Klebsiella pneumoniae by Isabel Ramón Roth, Pavel Kats, Timm Fiebig, Françoise Routier, Roman Fedorov, Larissa Dirr, Jana I. Führing

“…Targeting the respective molecular interfaces, which are absent in human UGP, could provide a means of selectively inhibiting the bacterial virulence factor UGP and potentially rendering pathogenic species avirulent.IMPORTANCEThe enzyme uridine diphosphate-glucose pyrophosphorylase (UGP) is important for the virulence of bacterial pathogens and, therefore, a potential drug target. …”
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Relationship between weapon size and six key behavioural and physiological traits in males of the European earwig by Blackwell, Samantha E M, Pasquier, Laura, Dupont, Simon, devers, Severine, Lecureuil, Charlotte, Meunier, Joël

“…We sampled hundreds of males from two populations, selected 60 males with the longest and shortest forceps from each population, and then measured locomotor performance, boldness, aggregation behaviour, survival under harsh conditions, sperm storage, and survival after pathogen exposure. Contrary to our predictions, we detected no main association between forceps length and the traits measured. …”
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Clinical Characteristics and Nomogram for Predicting Mortality in Patients with Postoperative Bloodstream Infection in Surgical Intensive Care Unit by Zengli Xiao, Yao Sun, Huiying Zhao, Youzhong An

“…The distribution of pathogens and clinical characteristics of patients with PBSI were analyzed. …”
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Microbial Predominance and Antimicrobial Resistance in a Tertiary Hospital in Northwest China: A Six-Year Retrospective Study of Outpatients and Patients Visiting the Emergency Dep... by Caifeng Wang, Wen Li, Juanjuan Gao, Dancheng Zhang, Yali Li, Fang Li, Jine Lei

“…Timely understanding of microbial pathogen profiles and the change of antimicrobial resistance provide an important guidance for effective and optimized use of antibiotics in local healthcare systems. …”
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Feruloyl-amides as natural antimicrobials for crop and food protection by Denise Dozio, Sharmila Ghosh, Daniele Alessandro Consolini, Josè Luis Ermini Starna, Loris Pinto, Federico Baruzzi, Martina Letizia Contente, Andrea Pinto, Paolo Cortesi, Salvatore Princiotto, Andrea Kunova, Sabrina Dallavalle

“…The compounds were tested against fungal and bacterial pathogens to assess their antimicrobial potential. …”
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Prevention of White Spot Syndrome Virus Infection on Penaeus monodon by Immersion in CEPM Extract of Avicennia sp. and Sonneratia sp. by D. Wahjuningrum, S.H. Sholeh, Sri Nuryati

“…Prevention of disease infection using chemicals can offer negative impacts on water, pathogen resistance and consumers.  This study was conducted to examine the efficacy of an alternative prevention compound as liquid mangrove extract (CEPM) from Avicennia sp. and Sonneratia sp. …”
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The Development of a One-Step PCR Assay for Rapid Detection of an Attenuated Vaccine Strain of Duck Hepatitis Virus Type 3 in Korea by Cheng-Dong Yu, Jong-Yeol Park, Sang-Won Kim, Yu-Ri Choi, Se-Yeoun Cha, Hyung-Kwan Jang, Min Kang, Bai Wei

“…Duck hepatitis A virus type 3 (DHAV-3) is a viral pathogen that causes acute, high-mortality hepatitis in ducklings, and vaccination with attenuated live vaccines is currently the main preventive measure against it. …”
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Resistance to causal agents of late blight and golden potato nematode of the modern cultivars of seed potatoes and their phytosanitary status in various agroclimatic zones of the E... by A. V. Khiutti, D. A. Rybakov, T. A. Gavrilenko, O. S. Afanasenko

“…The active expansion of foreign potato cultivars on the territory of the Russian Federation has led to a change in the dominant pathogen species and to the emergence of new pathotypes of causal agents of harmful potato diseases. …”
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The influence of farm connectedness on foot‐and‐mouth disease outbreaks in livestock by Jean B. Contina, Rachel L. Seibel, Bhim Chaulagain, Karasi B. Mills, Michael J. Tildesley, Christopher C. Mundt

“…Host connectivity provides early information on the host‐pathogen landscape and could be used as an assessment tool for predicting epidemic risks, as well as enabling preemptive control strategies to limit the size of disease outbreaks.…”
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Generation and characterization of chicken monocyte-derived dendritic cells by Elie Ngantcha Tatchou, Elie Ngantcha Tatchou, Romane Milcamps, Romane Milcamps, Guillaume Oldenhove, Bénédicte Lambrecht, Fiona Ingrao

“…However, these responses were downregulated after 24 hours.ConclusionThese findings provide a comprehensive characterization of chicken MoDCs and suggest their potential as a model for studying host-pathogen interactions.…”
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Intestinal obstruction caused by disseminated mycobacterium avium complex disease following solid organ transplantation: a case report by Akane Mita, Sho Nakakubo, Yusuke Nishimura, Hideki Shima, Masaaki Watanabe, Tsuyoshi Shimamura, Satoshi Konno

“…Abstract Background Mycobacterium avium complex (MAC) is a common pathogen causing non-tuberculous mycobacterial infections, primarily affecting the lungs. …”
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Cell-free supernatants from plant growth-promoting rhizobacteria Bacillus albus strains control Aspergillus flavus disease in peanut and maize seedlings by Lai Loi Trinh, Kim Ngoc Le, Hoang Anh Le Lam, Hoai Huong Nguyen

“…Abstract Background Aspergillus flavus, a seed-borne fungal pathogen, colonizes host plants and exploits nutrients, hindering the growth of seedlings such as peanut and maize. …”
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Cell Wall Protein 2 as a Vaccine Candidate Protects Mice Against <i>Clostridioides difficile</i> Infection by Shaohui Wang, Joshua Heuler, Jessica Bullock, Junling Qin, Soumyadeep Chakraborty, Agbendeh Lubem Nathaniel, Shifeng Wang, Xingmin Sun

“…Background/Objectives: <i>Clostridioides difficile</i> is a Gram-positive, spore-forming enteric pathogen that causes intestinal disorders, including inflammation and diarrhea, primarily through toxin production. …”
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γ-Aminobutyric Acid (GABA) Metabolic Bypass Plays a Crucial Role in Stress Tolerance and Biofilm Formation in <i>C. sakazakii</i> ATCC 29544 by Jiangchao Wu, Yigang Yu, Fengsong Liu, Yifang Cao, Jiahao Ren, Yiting Fan, Xinglong Xiao

“…<i>Cronobacter sakazakii</i> is a foodborne pathogen characterized by its robust stress tolerance and ability to form biofilms, which facilitates its survival in powdered infant formula (PIF) processing environments for prolonged periods. …”
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Research Progress on the Role of Inflammasomes in Kidney Disease by Kun Chi, Xiaodong Geng, Chao Liu, GuangYan Cai, Quan Hong

“…Inflammasomes are assembled by sensing pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs) and initiate inflammatory responses by activating caspase-1. …”
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Sero-epidemiological Study of Toxoplasma gondii among Pregnant Women in Akre City by Hogir Mohammed Shukri Saadi, Ahmed Jumaa Ahmed

“…Many previous studies were suggested this pathogen transmits by ingesting of undercooked or raw meat contaminated with the oocytes of this parasite. …”
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Functional Prediction of Hypothetical Proteins from and Validation of the Predicted Models by Using ROC Curve Analysis by Md. Amran Gazi, Sultan Mahmud, Shah Mohammad Fahim, Mohammad Golam Kibria, Parag Palit, Md. Rezaul Islam, Humaira Rashid, Subhasish Das, Mustafa Mahfuz, Tahmeed Ahmeed

“…Shigella spp. constitutes some of the key pathogens responsible for the global burden of diarrhoeal disease. …”
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Endophytic Colletotrichum siamense for Biocontrol and Resistance Induction in Guarana Seedlings by Luana L. Casas, José O. Pereira, Pedro Q. Costa-Neto, José F. Silva, Lucas N. Almeida, Roberto A. Bianco, João L. Azevedo

“…Leaflets were randomly collected from each treatment group at 0, 48, 72, and 96 hours after pathogen inoculation and analyzed for total protein and enzyme production (POX, PAL, and CHI). …”
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Role of nasal microbiota in regulating host anti-influenza immunity in dogs by Jinzhu Geng, Yuhao Dong, Hao Huang, Xia Wen, Ting Xu, Yanbing Zhao, Yongjie Liu

“…Abstract Background Numerous studies have confirmed a close relationship between the pathogenicity of influenza and respiratory microbiota, but the mechanistic basis for this is poorly defined. …”
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