Evaluation of Bacterial Load and Antibiotic Resistance Pattern of Staphylococcus aureus from Ready-to-Eat Raw Beef in Bahir Dar City, Ethiopia by Bizuneh Tsehayneh, Taddesse Yayeh, Birhan Agmas

“…Staphylococcus aureus is one of the most important causes of food-borne intoxication and the most frequent antibiotic-resistant pathogen in the world. Regular evaluation of the current safety status of food is a proactive measure to minimize the possible danger of food-borne pathogens. …”
Get full text

Diagnosing gastrointestinal infections based on cycle threshold cut-offs of PCR by Rania Karam, Peter Kechker, Shifra Ken-Dror, Avi Peretz, Maya Azrad

“…This study suggests to consider a Ct threshold for each pathogen in order to reduce inaccurate diagnosis. Alternatively, culture should be performed for PCR-positive samples.…”
Get full text

Helicobacter Pylori infection in systemic sclerosis and its association with upper gastrointestinal dysfunction by Chilukuri Balaji, Mahendran Bhuvanesh, Chinnadurai Saranya, Ramamoorthy Ramesh, Mayilsamy Saravanan, Sankaralingam Rajeswari

“…Helicobacter pylori (H. pylori) a pathogen well known to cause gastric ulcers and has been associated with several autoimmune diseases. …”
Get full text

Habitat sharing and interspecies interactions in caves used by bats in the Republic of Congo by Morgane Labadie, Serge Morand, Mathieu Bourgarel, Fabien Roch Niama, Guytrich Franel Nguilili, N’Kaya Tobi, Alexandre Caron, Helene De Nys

“…There is a need to protect bat populations and to mitigate the risks associated with pathogen spillover. Caves are key habitats for many bat species, which use them as roosting and breeding sites. …”
Get full text

In-Depth Global Analysis of Transcript Abundance Levels in Porcine Alveolar Macrophages Following Infection with Porcine Reproductive and Respiratory Syndrome Virus by Laura C. Miller, John D. Neill, Gregory P. Harhay, Kelly M. Lager, William W. Laegreid, Marcus E. Kehrli

“…Porcine reproductive and respiratory syndrome virus (PRRSV) is a major pathogen of swine worldwide and causes considerable economic loss. …”
Get full text

Greenbug resistance in barley landraces from Uzbekistan by E. E. Radchenko, K. D. Dyatlova, D. E. Akimova, I. A. Zveinek

“…Cultivation of resistant varieties can significantly limit the pathogen’s harmfulness. At the same time, specific interaction with the genotypes of the host plant, characteristic of S. graminum, requires a continuous search for new resistance donors to broaden the genetic diversity of barley cultivars. …”
Get full text

Chitosan Modulates Inflammatory Responses in Rats Infected with Enterotoxigenic Escherichia coli by Gang Liu, Shuai Chen, Guiping Guan, Jun Tan, Naif A. Al-Dhabi, Hongbing Wang, Veeramuthu Duraipandiyan, Jun Fang

“…This study aims to investigate the effects of dietary chitosan (COS) on gastrointestinal pathogen resistance in mice model. For two weeks, a control group of ICR mice received a basal diet whilst the intervention group received the basal diet supplemented with 300 mg/kg COS. …”
Get full text

Evolution and importance of Molecular Microbiology in the Laboratory of the Provincial Center for Hygiene, Epidemiology and Microbiology by María de Lourdes Sánchez Alvarez, Rafael Abreu Duarte, Edenis García Alvarez, Adrian Fernández García, Ermis Alexander González Martínez, Maidelys Mendoza Acosta

“…Introduction: the need to have rapid, sensitive and specific laboratory techniques for the detection of pathogens that are difficult to diagnose led to the creation of the Molecular Biology Laboratory at the Provincial Center of Hygiene, Epidemiology and Microbiology of Villa Clara. …”
Get full text

Mycobacterium bovis BCG Surface Antigens Expressed under the Granuloma-Like Conditions as Potential Inducers of the Protective Immunity by Yingyu Chen, Lia Danelishvili, Sasha J. Rose, Luiz E. Bermudez

“…We also demonstrated that the pathogen exposed to the biologically relevant environment has greater binding and invasion abilities to host cells than those of bacteria incubated under regular laboratory conditions. …”
Get full text

Genome-Wide Identification and Characterization of the LRR-RLK Gene Family in Two Vernicia Species by Huiping Zhu, Yangdong Wang, Hengfu Yin, Ming Gao, Qiyan Zhang, Yicun Chen

“…Leucine-rich repeat receptor-like kinases (LRR-RLKs) make up the largest group of RLKs in plants and play important roles in many key biological processes such as pathogen response and signal transduction. To date, most studies on LRR-RLKs have been conducted on model plants. …”
Get full text

Exploitation of Unconventional CD8 T-Cell Responses Induced by Engineered Cytomegaloviruses for the Development of an HIV-1 Vaccine by Joseph Bruton, Tomáš Hanke

“…Despite some safety concerns regarding using HCMV as a vaccine vector in humans, there is a vision of immune programming of HCMV to induce pathogen-tailored CD8⁺ T-cells effective against HIV-1 and other life-threatening diseases.…”
Get full text

Controlling Listeria monocytogenes Scott A on Surfaces of Fully Cooked Turkey Deli Product Using Organic Acid-Containing Marinades as Postlethality Dips by Gerardo Casco, Jennifer L. Johnson, T. Matthew Taylor, Carlos N. Gaytán, Mindy M. Brashears, Christine Z. Alvarado

“…The application of the SL/PL/SDA treatment to turkey product surfaces extended the lag phase through 42 d, with pathogen numbers declining after 21 d. Combination organic acid dips prolonged the lag phase for 2 to 6 wk on turkey product surfaces and can be useful as antimicrobial agents for Lm control on postlethality exposed sliced deli products.…”
Get full text

Identification of <i>Rpv3</i> and <i>Rpv12</i> loci in the progenies of the ‘Talisman’ grape cultivar by E. T. Ilnitskaya, M. V. Makarkina, T. D. Kozina, E. A. Kozhevnikov, V. S. Petrov

“…Currently, when implementing breeding programs to produce pathogen-resistant grape genotypes, the DNA marker assessment method is used both directly in breeding-oriented selection and in evaluation of the initial gene pool. …”
Get full text

Occurrence and Antimicrobial Resistance Pattern of Listeria monocytogenes Isolated From Bovine’s Milk and Meat in Mekelle City, Ethiopia by Tesfay Hailu, Getachew Gugsa, Yisehak Tsegaye, Meselu Ahmed, Nesibu Awol

“…Listeria monocytogenes is an opportunistic and emerging foodborne zoonotic pathogen that encompasses a diversity of strains with varied virulence and can cause serious human and animal infections worldwide. …”
Get full text

Synthesis and Antimicrobial Evaluation of a New Series of N-1,3-Benzothiazol-2-ylbenzamides by Domenico Armenise, Alessia Carocci, Alessia Catalano, Marilena Muraglia, Ivana Defrenza, Nicolino De Laurentis, Antonio Rosato, Filomena Corbo, Carlo Franchini

“…However, it is also an opportunistic pathogen and has emerged as a leading cause of hospital-acquired extraintestinal infections. …”
Get full text

Clinical Characteristics and Microorganisms Isolated in Community-Acquired Pneumonia in the COVID-19 Period by Meritxell Gavalda, Maria Isabel Fullana, Adrià Ferre, Rebecca Rowena Peña, Julen Armendariz, Orla Torrallardona, Aina Magraner, Alejandro Lorenzo, Carles García, Gemma Mut, Lluís Planas, Carla Iglesias, Pablo Fraile-Ribot, Maria Dolores Macia Romero, Melchor Riera, Mercedes García-Gasalla

“…Molecular tests are available for multiple pathogen detection and are under research to improve the causal diagnosis. …”
Get full text

Design of a new class of broad-spectrum therapeutics targeted to drug-resistant bacteria by Amrutha Surendran, Agnes Turnbull, Allen Flockhart, Fern Findlay-Greene, Martyna Nowosielska, Donald Morrison, David J. Mincher, Samantha Donnellan

“…Key policy highlights Development of a novel class of antimicrobial compounds Drug screen against a WHO ‘high’ priority drug-resistant pathogen that poses the greatest threat to human health (methicillin-resistant Staphylococcus aureus) Drug screen against a surrogate for Mycobacterium tuberculosis, one of the leading causes of mortality worldwide.…”
Get full text

Antimicrobial peptide AP2 ameliorates Salmonella Typhimurium infection by modulating gut microbiota by Lianglan Li, Qiufen Mo, Yi Wan, Yuanhao Zhou, Weiqin Li, Weifen Li

“…Abstract Background Endogenous antimicrobial peptides and proteins are essential for shaping and maintaining a healthy gut microbiota, contributing to anti-inflammatory responses and resistance to pathogen colonization. Salmonella enterica subsp. enterica serovar Typhimurium (ST) infection is one of the most frequently reported bacterial diseases worldwide. …”
Get full text

Genomic insights into a clinical Salmonella Typhimurium isolate carrying plasmid-mediated blaNDM-5 by Fan Huang, Genglin Guo, Lu Feng, Tongbo Cai, Xu Huang

“…Moreover, we conducted an epidemiologic analysis and focused on studying the mechanisms of plasmid-mediated blaNDM transmission, incorporating genomes deposited in the NCBI Pathogen Detection database. Results: The clinical isolate 23S9 belonged to serovar Typhimurium, antigenic profile 4:i:-, ST34, and carried pNDM_23S9 harbouring several antimicrobial resistance genes, including aac(6′)-Ib-cr6, OXA-1, catB3, arr-3, qacEdeltal and blaNDM. …”
Get full text

Recent advances in bacterial outer membrane vesicles: Effects on the immune system, mechanisms and their usage for tumor treatment by Shuo Xiang, Qiufang Yao, Arshad Khan, Dong Wang

“…Bacterial outer membrane vesicles (OMVs) secreted by gram-negative bacteria are nanoscale lipid bilayer structures rich in bacterial antigens, pathogen-associated molecular patterns (PAMPs), various proteins, and vesicle structures. …”
Get full text