The Pathology of Orthopedic Implant Failure Is Mediated by Innate Immune System Cytokines by Stefan Landgraeber, Marcus Jäger, Joshua J. Jacobs, Nadim James Hallab

“…However, a consensus of studies agrees that the dominant form of this response is due to innate reactivity by macrophages to implant debris where both danger (DAMP) and pathogen (PAMP) signalling elicit cytokine-based inflammatory responses. …”
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Effectiveness of a commercial LAMP technology-based kit for rapid detection of Bursaphelenchus xylophilus in Pinus pinaster by María Menéndez-Gutiérrez, Lucía Villar, Raquel Díaz

“…Don under field conditions, thus contributing to the advancement of efficient surveillance and management strategies to combat this pathogen. Material and methods: In three different experiments, the detection rate of the B. xylophilus LAMP kit was compared to the traditional Baermann funnel technique for nematode extraction. …”
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Inflammasomes in neurodegenerative diseases by Qianchen Wang, Songwei Yang, Xuan Zhang, Shanshan Zhang, Liping Chen, Wanxue Wang, Naihong Chen, Jiaqing Yan

“…Abstract Inflammasomes represent a crucial component of the innate immune system, which respond to threats by recognizing different molecules. These are known as pathogen-associated molecular patterns (PAMPs) or host-derived damage-associated molecular patterns (DAMPs). …”
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Enterococcus faecium HDRsEf1 Protects the Intestinal Epithelium and Attenuates ETEC-Induced IL-8 Secretion in Enterocytes by Zhongyuan Tian, Xiaofang Liu, Ran Dai, Yuncai Xiao, Xiliang Wang, Dingren Bi, Deshi Shi

“…In this study, using the IPEC-J2 cell line to mimic intestinal epithelial cells and enterotoxigenic Escherichia coli (ETEC) K88ac as a representative intestinal pathogen, the mechanism underlying Ef1 protection against an enteropathogen was investigated. …”
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Occurrence of Virulence Genes and Antimicrobial Resistance of E. coli O157:H7 Isolated from the Beef Carcass of Bahir Dar City, Ethiopia by Habtamu Yalew Ayenew, Birhan Agmas Mitiku, Tesfaye Sisay Tesema

“…E. coli O157:H7 is one of the most virulent foodborne pathogens. The aim of this study was to isolate E. coli O157:H7, determine virulence genes carried by the organism, and assess the antimicrobial susceptibility pattern of the isolates from beef carcass samples at Bahir Dar city. …”
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Pyoverdine, the Major Siderophore in Pseudomonas aeruginosa, Evades NGAL Recognition by Mary E. Peek, Abhinav Bhatnagar, Nael A. McCarty, Susu M. Zughaier

“…Pseudomonas aeruginosa is the most common pathogen that persists in the cystic fibrosis lungs. …”
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Plant Colonization by Biocontrol Bacteria and Improved Plant Health: A Review by Roohallah Saberi Riseh, Fariba Fathi, Mozhgan Gholizadeh Vazvani, Mika Tapio Tarkka

“…It highlights the need for a deeper understanding of the colonization mechanisms employed by biocontrol bacteria to enhance their efficacy in plant pathogen control. The present review deals with the in-depth understanding of steps involved in host colonization by biocontrol bacteria. …”
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Dendritic Cells from Aged Subjects Display Enhanced Inflammatory Responses to Chlamydophila pneumoniae by Sangeetha Prakash, Sudhanshu Agrawal, Dandan Ma, Sudhir Gupta, Ellena M. Peterson, Anshu Agrawal

“…Chlamydophila pneumoniae (CPn) is a common respiratory pathogen that causes a chronic and persistent airway infection. …”
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Metagenomic next-generation sequencing assists in the diagnosis of visceral leishmaniasis in non-endemic areas of China by Rui Zhao, Guilun He, Lin Xiang, Melinda Ji, Rongheng He, Xudong Wei

“…Direct identification of infected tissues is currently the primary method of diagnosis; however, the low sensitivity and inconvenience of microscopic examination in detecting amastigotes, parasitic manifestations of Leishmania, leads to the possibility of misdiagnosis, delayed diagnosis, and underdiagnosis.MethodsWith the development of metagenomic nextgeneration sequencing (mNGS) technology for pathogen identification, it is possible to detect specific nucleic acid sequences characteristic of Leishmania parasites, which opens new avenues for the more accurate diagnosis of leishmaniasis. …”
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Recombinant SpTransformer proteins bind to specific sites on sea urchin phagocytes and modulate SpTransformer gene expression and immune responsiveness by Ryley S. Crow, Leon Grayfer, L. Courtney Smith

“…IntroductionThe California purple sea urchin, Strongylocentrotus purpuratus, relies exclusively on an innate immune system to survive in its pathogen rich marine environment. Central to this defense is the SpTransformer (SpTrf) gene family that is unique to the euechinoid group of echinoderms. …”
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Serotype Distribution and Antimicrobial Resistance Profile of Haemophilus influenzae Isolated from School Children with Acute Otitis Media by Dodi Safari, Daniel Joko Wahyono, Wisnu Tafroji, Anton Budhi Darmawan, Yayah Winarti, Wahyu Dwi Kusdaryanto, Wisiva Tofriska Paramaiswari, Hendro Pramono, Meyta Pratiwi, Muhamad Riza Chamadi

“…Haemophilus influenzae is a Gram-negative opportunistic bacterial pathogen of the human respiratory tract. This study describes the prevalence, serotype distribution, and susceptibility profiles of H. influenzae strains isolated from the nasopharynx of school children with acute otitis media (AOM) in Banyumas Regency, Central Java, Indonesia. …”
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Expression of Helicobacter pylori hspA Gene in Lactococcus lactis NICE System and Experimental Study on Its Immunoreactivity by Xiao-Juan Zhang, Shu-Ying Feng, Zhi-Tao Li, Yan-Ming Feng

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A comprehensive method on black-legged tick larvae and nymph feeding on mice to study Lyme disease transmission and acquisition by Aaron Scholl, Bingjie Li, John Dennis, Sandip De

“…Human-driven changes in climate and ecosystems have expanded the habitat of pathogen-carrying ticks, facilitating the spread of these infections. …”
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Control of <i>Vibrio parahaemolyticus</i> in Seafood Using the Combination of Lytic Phages and Citric Acid by Xiaoshuang Zheng, Lu Gao, Lei Yuan, Caowei Chen, Zhenquan Yang

“…<i>Vibrio parahaemolyticus</i> is a key foodborne pathogen in seafood that poses health risks to consumers. …”
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Occurrence of <i>Salmonella</i> and presumptive <i>Bacillus cereus</i> in sesame products from Swiss retail stores by Karen Barmettler, Sara Boss, Michael Biggel, Roger Stephan

“… Sesame products such as tahini (tahin) or halva (halwa or helva), originating from Arabic cuisine, are becoming increasingly popular in Switzerland. Pathogens, such as Salmonella, can contaminate sesame products, as evidenced by various product recalls. …”
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A strategy for controlling Hypervirulent Klebsiella pneumoniae: inhibition of ClpV expression by Wenke Liu, Dan Wang, Qiangxing He, Shiwen Cao, Jiaxin Cao, Huajie Zhao, Junwei Cui, Fan Yang

“…In the present study, the clpV gene deletion strain of hvKP (ΔclpV-hvKP) was constructed using CRISPR-Cas9 technology, and the biological characteristics of ΔclpV-hvKP were investigated to explore the new targets for controlling this pathogen. The results showed that clpV gene deletion did not affect the growth ability of hvKP. …”
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Ecological relationships of Haemaphysalis longicornis Neumann with other tick species on wildlife hosts at cow–calf farms implementing integrated pest management in eastern Tenness... by Rebecca A. Butler, Lisa I. Muller, Dan Grove, Rebecca T. Trout Fryxell, Ala Tabor

“…Longhorned tick (Haemaphysalis longicornis) is an invasive tick species that parasitizes a variety of vertebrate hosts and transmits pathogens affecting humans and livestock in the United States (US). …”
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Patterns of Antimicrobial Resistance in the Causative Organisms of Spontaneous Bacterial Peritonitis: A Single Centre, Six-Year Experience of 1981 Samples by Sara Sheikhbahaei, Alireza Abdollahi, Nima Hafezi-Nejad, Elham Zare

“…The most prevalent isolated pathogen was E. coli (33.8%), followed by staphylococcus aureus (8.9%) and Enterococcus (8.6%). …”
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Adipose Tissue Remodeling as Homeostatic Inflammation by Michiko Itoh, Takayoshi Suganami, Rumi Hachiya, Yoshihiro Ogawa

“…Such a sustained interaction between endogenous ligands derived from parenchymal cells and pathogen sensors expressed in stromal immune cells should lead to chronic inflammatory responses ranging from the basal homeostatic state to diseased tissue remodeling, which may be referred to as “homeostatic inflammation”. …”
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Study of the vaccination effects against <i>Staphylococcus aureus</i>, causing mastitis and endometritis in cows by E. V. Ivanov, A. V. Kapustin, N. N. Avduevskaya

“…In the test group, the pathogen was detected in 20% of cases, which is 2.5 times lower than in the control group.…”
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