Intramedullary Chondrosarcoma of Proximal Humerus by Pratiksha Yadav, Dolly Thakkar, S. S. Thind

“…Primary chondrosarcoma is the third most frequent primary malignancy of bone after myeloma and osteosarcoma. It is ranging from slow growing nonmetastasising lesions to highly aggressive lesions. …”
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Carbohydrate ligand engagement with CD11b enhances differentiation of tumor-associated myeloid cells for immunotherapy of solid cancers by Mei Zhang, Veronique Roche, Victor Sandoval, Claire Wolford, Zachary Senders, Julian Anthony Kim, Susan Pereira Ribeiro, Alex Yicheng Huang, Rafick-Pierre Sekaly, Joshua Lyons

“…This engagement significantly impacts the biological function of tumor-associated inflammatory monocytes (TAIMs) in osteosarcoma, advanced melanoma, and PDAC backgrounds. …”
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Involvement of HMGB1 in Resistance to Tumor Vessel-Targeted, Monoclonal Antibody-Based Immunotherapy by Vito Pistoia, Annalisa Pezzolo

“…HMGB1-induced autophagy promotes tumor resistance to chemotherapy, as shown in different models of malignancy, for example, osteosarcoma, leukemia, and gastric cancer. To the best of our knowledge, there is virtually no information on the relationships between HMGB1 and resistance to immunotherapy. …”
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Predicting cell morphological responses to perturbations using generative modeling by Alessandro Palma, Fabian J. Theis, Mohammad Lotfollahi

“…We show that IMPA accurately captures morphological and population-level changes of both seen and unseen perturbations on breast cancer and osteosarcoma cells. Additionally, IMPA accounts for batch effects and can model perturbations across various sources of technical variation, further enhancing its robustness in diverse experimental conditions. …”
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The role of tribbles homolog 2 in cell proliferation by Wenkang Zhang, Mingkang Li, Minhao Zhang, Gaoliang Yan, Chengchun Tang

“…TRIB2 is not only involved in the physiological proliferation of cells (granulosa cells, myoblasts, naive T cells, and thymocytes) during normal development but also in the pathological proliferation of vascular smooth muscle cells and a variety of cancer cells (lung cancer cells, liver cancer cells, leukemia cells, pancreatic cancer cells, gastric cancer cells, prostate cancer cells, thyroid cancer cells, cervical cancer cells, melanoma cells, colorectal cancer cells, ovarian cancer cells and osteosarcoma cells) under disease conditions. Its expression level and functional role predominantly hinge on the specific tissue and cell type it targets. …”
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Clinical Trials of Immunogene Therapy for Spontaneous Tumors in Companion Animals by Gerardo Claudio Glikin, Liliana María Elena Finocchiaro

“…A variety of tumors such as canine melanoma, soft tissue sarcomas, osteosarcoma and lymphoma, feline fibrosarcoma, and equine melanoma were subjected to different treatment approaches. …”
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Research progress of circRNAs in bone-related diseases by Xianming Hua, Lingfeng Yu, Hao Zhu, Yan Zhu, Gentao Fan, Guangxin Zhou, Guangxin Zhou, Guangxin Zhou

“…Studies have shown that circRNAs play an irreplaceable role in the pathogenesis, disease progression, diagnosis, and targeted therapy of motor system tumors (osteosarcoma), metabolic diseases (osteoporosis), and degenerative diseases (osteonecrosis of the femoral head, osteoarthritis, intervertebral disc degeneration). …”
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Maternal Mortality: 10 Year Experience of a Tertiary Center in Turkey by Erdem Fadiloglu, Canan Unal, Atakan Tanacan, Serpil Ocal, Banu Kilicaslan, Seda Banu Akinci, Arzu Topeli, M. Sinan Beksac

“…Maternal mortality causes were cardiopulmonary failure secondary to veno-occlusive disease, septic shock secondary to osteosarcoma, pulmonary thromboembolism secondary to metastatic breast cancer, septic shock secondary to cholecystitis, and postpartum hemorrhage secondary to Niemann–Pick disease. …”
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Two Cases of Sarcoma Arising in Giant Cell Tumor of Bone Treated with Denosumab by Cory Julian Broehm, Erika L. Garbrecht, Jeff Wood, Therese Bocklage

“…We report two cases of sarcomatous transformation of GCT to osteosarcoma in patients receiving denosumab. One was a 59-year-old male with a 12-year history of GCT and multiple recurrences taking denosumab for 2.5 years. …”
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Numb Chin Syndrome as First Symptom of Diffuse Large B-Cell Lymphoma by Mario Carbone, Francesco Della Ferrera, Lucio Carbone, Gaia Gatti, Marco Carrozzo

“…Many malignant and metastatic neoplasms are causing this syndrome, like primary osteosarcoma, squamous cell carcinoma, and mandibular metastasis of primary carcinoma of breast, lung, thyroid, kidney, prostate, and nasopharynx. …”
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Primary Clear Cell Chondrosarcoma of the Spine: A Case Report of a Rare Entity and a Review of the Literature by Nikolaos A. Paidakakos, Aristides Rovlias, Evaggelos Rokas, Spyridon Theodoropoulos, Patroklos Katafygiotis

“…Chondrosarcoma is the third most common primary malignant bone tumor after osteosarcoma and Ewing’s sarcoma. Clear cell chondrosarcoma is a rare subtype variant of chondrosarcoma, most commonly encountered in the proximal part of the femur or humerus. …”
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Saving a Child’s Elbow Joint: A Novel Reconstruction for a Tumour of the Distal Humerus by Calogero Graci, Czar Louie Gaston, Robert Grimer, Lee Jeys, Korhan Ozkan

“…We describe a 12-year-old girl with parosteal osteosarcoma of the distal right humerus treated by en bloc resection, intraoperative extracorporeal irradiation, and implantation. …”
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Durvalumab and tremelimumab in patients with advanced rare cancer: a multi-centre, non-blinded, open-label phase II basket trialResearch in context by Abha A. Gupta, Anna Tinker, Derek Jonker, Rahma Jamal, Hal Hirte, Eric W. Winquist, Quincy Chu, Christian Kollmannsberger, Ralph Wong, Thierry Alcindor, Torsten O. Nielsen, Ming Tsao, Tricia R. Cottrell, Diane Provencher, John Hilton, Monika K. Krzyżanowska, Christine Elser, Sebastien Hotte, Joana Sederias, Siwei Zhang, Wei Tu, Janet Dancey

“…Durable responses were noted in all cohorts except for osteosarcoma. The overall response rate for eligible patients was 16% (95% CI: 10–23%). …”
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Effects of Genipin Concentration on Cross-Linked Chitosan Scaffolds for Bone Tissue Engineering: Structural Characterization and Evidence of Biocompatibility Features by Simona Dimida, Amilcare Barca, Nadia Cancelli, Vincenzo De Benedictis, Maria Grazia Raucci, Christian Demitri

“…Finally, basic biocompatibility was investigated in vitro, by evaluating proliferation of two human-derived cell lines, namely, the MG63 (human immortalized osteosarcoma) and the hMSCs (human mesenchymal stem cells), as suitable cell models for bone tissue engineering applications of biomaterials.…”
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Regulatory Role of the RUNX2 Transcription Factor in Lung Cancer Apoptosis by Camila Bernal, Andrea Otalora, Alejandra Cañas, Alfonso Barreto, Karol Prieto, Martin Montecino, Adriana Rojas

“…Current studies have confirmed that RUNX2 is closely related to the proliferation, invasion, and bone metastasis of multiple cancer types, such as osteosarcoma, breast cancer (BC), prostate cancer, gastric cancer, colorectal cancer, and lung cancer. …”
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ANTITUMOR EFFECT OF ELECTROMAGNETIC FIELDS AND THEIR EFFECT ON PAIN IN EXPERIMENTAL AND CLINICAL ONCOLOGY by E. M. Frantsiyants, E. A. Sheiko

“…It has been shown that chemotherapy together with electromagnetic fields induces apoptosis and has an inhibitory effect on DNA synthesis in osteosarcoma cells, breast cancer, colon cancer, melanoma and other tumors. …”
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Paravertebral Well-Differentiated Liposarcoma with Low-Grade Osteosarcomatous Component: Case Report with 11-Year Follow-Up, Radiological, Pathological, and Genetic Data, and Liter... by Nicolas Macagno, Stéphane Fuentes, Gonzague de Pinieux, André Maues de Paula, Sébastien Salas, Jean-Camille Mattéi, Charlotte Dupuis, Romain Appay, Alain Aurias, Henry Dufour, Dominique Figarella-Branger, Corinne Bouvier

“…After surgical resection, histopathological examination revealed a tumor harboring combined features of well-differentiated liposarcoma and low-grade osteosarcoma. Tumor cells displayed overexpression of MDM2, CDK4, and P16 by immunohistochemistry and CGH revealed amplification of 12q13-15 as the only genetic imbalance. …”
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Synergistic Approach of High-Precision 3D Printing and Low Cell Adhesion for Enhanced Self-Assembled Spheroid Formation by Chunxiang Lu, Aoxiang Jin, Chuang Gao, Hao Qiao, Huazhen Liu, Yi Zhang, Wenbin Sun, Shih-Mo Yang, Yuanyuan Liu

“…We successfully formed three types of spheroids—human immortalized epidermal cells (HaCaTs), umbilical cord mesenchymal stem cells (UC-MSCs), and human osteosarcoma cells (MG63s)—on the chip. Fluorescent viability staining confirmed the biocompatibility and reliability of the chip. …”
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Pregnancy after Cancer Treatment and Pregnancy Associated Cancer: A Single Center Experience with 96 Cases by Mert Turğal, Kemal Beksaç, Derman Başaran, Aslıhan Yazıcıoğlu, Özgür Özyüncü, Ömer Aran, M. Sinan Beksaç

“…The most common type of cancer was the breast cancer in 25 patients, followed by thyroid, leukemia, osteosarcoma, lymphoma and ovarian cancer. Patients were treated for their cancer with different modalities including surgery, chemotherapy and radiotherapy. …”
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scSMD: a deep learning method for accurate clustering of single cells based on auto-encoder by Xiaoxu Cui, Renkai Wu, Yinghao Liu, Peizhan Chen, Qing Chang, Pengchen Liang, Changyu He

“…Comprehensive evaluation on both public datasets and proprietary osteosarcoma data highlights the SMD model’s efficacy in achieving precise classifications for single-cell data clustering, showcasing its potential for advanced transcriptomic analysis. …”
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