All-Cause Mortality Risk in Australian Women with Impaired Fasting Glucose and Diabetes by Lelia L. F. de Abreu, Kara L. Holloway, Mohammadreza Mohebbi, Muhammad A. Sajjad, Mark A. Kotowicz, Julie A. Pasco

“…This study included 1167 women (ages 20–94 yr) enrolled in the Geelong Osteoporosis Study. Hazard ratios for all-cause mortality in diabetes, IFG, and normoglycaemia were calculated using a Cox proportional hazards model. …”
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Fracture Risk in Type 2 Diabetes: Current Perspectives and Gender Differences by Giuseppina T. Russo, Annalisa Giandalia, Elisabetta L. Romeo, Morabito Nunziata, Marco Muscianisi, Maria Concetta Ruffo, Antonino Catalano, Domenico Cucinotta

“…The pathophysiological mechanisms linking diabetes to osteoporosis have not been fully explained, but alterations in bone structure and quality are well described in diabetic subjects, likely due to a combination of different factors. …”
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Cross-trait multivariate GWAS confirms health implications of pubertal timing by Siquan Zhou, Yujie Xu, Jingyuan Xiong, Guo Cheng

“…Linkage disequilibrium score regression and Mendelian randomisation analysis establish causal associations between earlier puberty and both accelerated ageing and the risk of developing cardiovascular disease and osteoporosis. We find that alanine aminotransferase, glycated haemoglobin, high-density lipoprotein cholesterol and Parabacteroides levels are mediators of these relationships, and establish that controlling oily fish and retinol intake may be beneficial for promoting healthy pubertal development.…”
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Socioeconomic status and morbidity pattern among the elderly population in Bankura district, West Bengal by Ujjwal Das, Nishamani Kar

“…Hypertension was found to have the highest burden of morbidity, followed by bone diseases such as osteoporosis and osteoarthritis. Therefore, enhancing geriatric health services is urgently needed to improve their quality of life.…”
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Subchondral Insufficiency Fracture of the Femoral Head Caused by Excessive Lateralization of the Acetabular Rim by Tetsuya Kimura, Tomohiro Goto, Daisuke Hamada, Takahiko Tsutsui, Keizo Wada, Shoji Fukuta, Akihiro Nagamachi, Koichi Sairyo

“…We present a case of a 53-year-old woman with subchondral insufficiency fracture (SIF) of the femoral head without history of severe osteoporosis or overexertion. Plain radiographs showed acetabular overcoverage with excessive lateralization of the acetabular rim. …”
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Biological function of d-tryptophan: a bibliometric analysis and review by Fei Wang, Runyu Du, Yunxiao Shang

“…Furthermore, d-tryptophan plays a role in the therapy of atherosclerosis, osteoporosis, tuberculosis, and cancer.ConclusionThe results of bibliometric analysis highlight that future research should focus on the biological functions of d-tryptophan as a food preservative and its use in immunomodulation and drug development, providing strong guidance for future research.…”
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Dysglycaemia and Other Predictors for Progression or Regression from Impaired Fasting Glucose to Diabetes or Normoglycaemia by L. de Abreu, Kara L. Holloway, Mark A. Kotowicz, Julie A. Pasco

“…This study included 1167 women, aged 20–94 years, enrolled in the Geelong Osteoporosis Study. Multivariable logistic regression was used to identify predictors for progression to diabetes or regression to normoglycaemia (from IFG), over 10 years of follow-up. …”
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Rapid Destruction of the Humeral Head Caused by Subchondral Insufficiency Fracture: A Report of Two Cases by Kenichi Goshima, Katsuhiko Kitaoka, Junsuke Nakase, Hiroyuki Tsuchiya

“…Although shoulder RDA is rare, this disease should be included in the differential diagnosis of acute onset shoulder pain in elderly female patients with osteoporosis and persistent joint effusion.…”
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Periodontal Care as a Fundamental Step for an Active and Healthy Ageing by Carlo Cafiero, Marco Matarasso, Gaetano Marenzi, Vincenzo Iorio Siciliano, Loredana Bellia, Gilberto Sammartino

“…Diabetes mellitus, obesity, and osteoporosis are very frequent pathological situations in older age. …”
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miR-468-3p suppresses osteogenic differentiation of BMSCs by targeting Runx2 and inhibits bone formation by Tao Fang, Ranxi Zhang, Feng Song, Xueru Chu, Qin Fu, Qianqian Wu

“…Abstract An improved understanding of the molecular actions underpinning bone marrow mesenchymal stem cell (BMSC) differentiation could highlight new therapeutics for osteoporosis (OP). Current evidence indicates that microRNAs (miRNAs) exert critical roles in many biological systems, including osteoblast differentiation. …”
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Lipopolysaccharide inhibits osteoblast formation and receptor activator of nuclear factor-κB ligand degradation via autophagy inhibition by Huaizhi Zhang, Jianhua Lin, Xu Chen, Jianhui Dai, Haibin Lin

“…Lipopolysaccharide (LPS) and Receptor Activator of Nuclear Factor-κB Ligand (RANKL) are the two important factors causing bone loss, which is an important pathogenesis for osteoporosis. However, the relationship between LPS and RANKL is not yet clear. …”
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Current and future perspectives on clinical management of classic 21-hydroxylase deficiency by Analia Yogi, Kenichi Kashimada

“…Meanwhile, overtreatment with glucocorticoids causes iatrogenic Cushing’s syndrome which could result in growth impairment, obesity, osteoporosis, and hypertension. The dilemma of 21OHD treatment is that glucocorticoid supplementation therapy at physiological dosage does not sufficiently suppress ACTH, consequently leading to adrenal androgen excess. …”
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Effects of Obesity on Bone Mass and Quality in Ovariectomized Female Zucker Rats by Rafaela G. Feresin, Sarah A. Johnson, Marcus L. Elam, Edward Jo, Bahram H. Arjmandi, Reza Hakkak

“…Obesity and osteoporosis are two chronic conditions that have been increasing in prevalence. …”
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The Effect of Subchondral Claw-Deploying Lag Screw on Lateral Sliding Distance and Cut-Out in Treating Intertrochanteric Fractures by Mehmet Cakmak, Levent Horoz

“…Introduction: The incidence of intertrochanteric fractures has increased in recent years due to the growing elderly population at risk of hip fractures, primarily attributed to osteoporosis. Among hip fractures, the prevalence of intertrochanteric fractures is progressively rising. …”
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Trends and disparities in the surgical management of spinal fractures in Sweden during 2008–2023 by Niklas Barle, Michael Axenhus

“…Probable influencing factors may be increased life-spans and osteoporosis. This may also explain the observed shift towards older age groups in spinal fracture surgery. …”
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siRNA therapeutics for effective management of rheumatoid arthritis by Vishakha R. Chakole, Tathagata Dutta, Priyankar Sen

“…This property makes siRNA a valuable tool for developing RNAi therapeutics, particularly for managing conditions like osteoporosis, cancer, genetic disorders, and autoimmune disorders. …”
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Establishment of a UPLC-MS/MS Method for Studying the Effect of Salt-Processing on Tissue Distribution of Twelve Major Bioactive Components of Qing’e Pills in Rats by Jingxia Hou, Shangyang Lin, Jinlan Lu, Yu Wu, Li Wu, Zhipeng Chen, Weidong Li

“…Qing’e pills is clinically used for treating osteoporosis in postmenopausal women in China. Eucommiae Cortex and Psoraleae Fructus are the main herbs of Qing’e pills and are both required to be salt-processed. …”
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Effects of physical multimorbidity on cognitive decline trajectories among adults aged 50 years and older with different wealth status: a 17-year population-based cohort study by Chen Chen, Shan Zhang, Ning Huang, Mingyu Zhang, JinXin Fu, Jing Guo

“…Individuals with high wealth and hypertension/diabetes patterns have significantly lower composite global cognitive z scores over time as compared with respiratory/osteoporosis patterns. Physical multimorbidity at baseline is associated with the trajectory of cognitive decline, and the magnitude of the association increased over time. …”
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Bone Mineral Density in Thalassemia Major Patients from Antalya, Turkey by Ibrahim Aslan, Duran Canatan, Nihal Balta, Gulizar Kacar, Cengaver Dorak, Ahmet Ozsancak, Nurgul Oguz, Ruya Cosan

“…Conclusion. he prevalence of osteoporosis is high in patients with thalassemia major, possibly related to delayed puberty.…”
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A novel approach to intraoperative diagnosis of primary pigmented nodular adrenocortical disease by Nethrani Sameera Wijesekara Pathirana, Hasitha Udayakumara, A S K Banagala, M R Sumanatilleke, A V T Damayanthi, S R Constantine, G W Katulanda, Z T M Thowfeek, T Sasikanth, S Pathmanathan

“…Here, we describe a case of ACTH-independent CS due to primary pigmented nodular adrenocortical disease (PPNAD) in a 33-year-old female patient with several complications of CS, including diabetes, hypertension, osteoporosis and severe depression with suicidal ideation. …”
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