Discovering CRISPR-Cas system with self-processing pre-crRNA capability by foundation models by Wenhui Li, Xianyue Jiang, Wuke Wang, Liya Hou, Runze Cai, Yongqian Li, Qiuxi Gu, Qinchang Chen, Peixiang Ma, Jin Tang, Menghao Guo, Guohui Chuai, Xingxu Huang, Jun Zhang, Qi Liu

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In Vivo and In Vitro Study of a Polylactide-Fiber-Reinforced β-Tricalcium Phosphate Composite Cage in an Ovine Anterior Cervical Intercorporal Fusion Model by Janek Frantzén, Aliisa Pälli, Esa Kotilainen, Harri Heino, Bettina Mannerström, Heini Huhtala, Hannu Kuokkanen, George K. Sándor, Kari Leino, Matias Röyttä, Riitta Parkkola, Riitta Suuronen, Susanna Miettinen, Hannu T. Aro, Suvi Haimi

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Incorporating insulin into alginate-chitosan 3D-printed scaffolds: A comprehensive study on structure, mechanics, and biocompatibility for cartilage tissue engineering by Afsaneh Jahani, Mohammad Sadegh Nourbakhsh, Ali Moradi, Marzieh Mohammadi, Lobat Tayebi

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hnRNPU-mediated pathogenic alternative splicing drives gastric cancer progression by Guoguo Jin, Yanming Song, Shaobo Fang, Mingyang Yan, Zhaojie Yang, Yang Shao, Kexin Zhao, Meng Liu, Zhenwei Wang, Zhiping Guo, Zigang Dong

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Identification of Two Novel Immune Subtypes Characterized by Distinct Prognosis and Tumor Microenvironment in Osteosarcoma by Shunhan Yao, Meiling Deng, Xiaojing Du, Qingfeng Chen, Rongzhi Huang

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Fibrodysplasia Ossificans Progressiva and Pregnancy: A Case Series and Review of the Literature by Alexandra D. Forrest, Danielle M. Vuncannon, Jane E. Ellis, Zvi Grunwald, Frederick S. Kaplan

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Symptomatic Secondary Selective IgM Immunodeficiency in Adult Man with Undiagnosed Celiac Disease by Eli Magen, Viktor Feldman, Mishal Joseph, Hadari Israel

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Bilateral De Quervain Syndrome after Aromatase Inhibitor Administration: A Case Report and Review of the Literature by Konstantinos Papadimitriou, Panteleimon Kountourakis, Emmanouil Morakis, Vassilios Vassiliou, Vasileios Barbounis, Alexandros Ardavanis

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Intraarticular Involvement of Extraarticular Giant Cell Tumor of the Tendon Sheath in the Thumb of a Pediatric Patient: A Case Report by Aiko Makino, Susumu Saito, Tsuyoshi Taba

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Reduction in Surgical Wound Infection Rates Associated with Reporting Data to Surgeons by GD Taylor, M Buchanan-Chell, T Kirkland, M McKenzie, B Sutherland, R Wiens

“…Since inception through to December 1993, ssi rates have fallen 68% in clean contaminated general surgery cases (relative risk [rr] 0.36, 95% ci 0.2 to 0.6, P=0.0001), 64% in clean plastic surgery cases (rr 0.35, 95% ci 0.06 to 1.8), 72% in caesarean section cases (rr 0.23, 95% ci 0.03 to 1.96) and 42% in clean cardiovascular surgery cases (rr 0.59, 95% ci 0.34 to 1.0). In clean orthopedic surgery the ssi rate remained stable from 1987 through 1992. …”
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Comparison of the Effect of Adding Dexmedetomidine as an Adjuvant to Bupivacaine for Postoperative Pain Management in Patients Undergoing Shoulder Rotator Cuff Repair – A Randomize... by Shahryar Sane, Alireza Mahoori, Ali Tabrizi, Hamed Koohsoltani

“…Background: Shoulder rotator cuff repair postoperative pain management is more critical than orthopedic surgeries in other limbs. This study aimed to investigate the effect of adding dexmedetomidine as an adjuvant to bupivacaine for postoperative pain management. …”
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Glenohumeral Instability and Arm Pain in Overhead Throwing Athletes: A Correlational Study by Max Wardell, Doug Creighton, Carter Kovalcik

“… # Methods Actively competing baseball pitchers were recruited and evaluated once with the anterior-posterior Load and Shift examination procedure, the Kerlan-Jobe Orthopedic Clinic Shoulder and Elbow Questionnaire (KJOC), and the Functional Arm Scale for Throwers (FAST). …”
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Trends in spinal implant utilization and pricing by Gabrielle Lucia Dykhouse, Rachel A. Bratescu, Osama N. Kashlan, McGrath Lynn Jr., Roger Härtl, Galal A. Elsayed

“…Materials and Methods: Spine implant utilization and pricing averages between 2013 and 2022 were extracted from Orthopedic Network News. The total sample composed of 664,310 spine procedure purchase orders. …”
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Use of Antibiotics in Companion Animals from 133 German Practices from 2018 to 2023 by Roswitha Merle, Leonie Feuer, Katharina Frenzer, Jan-Lukas Plenio, Astrid Bethe, Nunzio Sarnino, Antina Lübke-Becker, Wolfgang Bäumer

“…Indications varied by species, with respiratory issues more frequent in cats and orthopedic problems in dogs. Body weight and breed characteristics influenced the likelihood of antibiotic treatment, with short-nosed breeds showing higher odds. …”
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Effect of Orthodontic Treatment on Airway Dimensions in Patients with Obstructive Sleep Apnea: A Prospective Study by Mohammad K. Alam, Mohammad Y. Hajeer, Abdullah H. Alshammari, Saud A. A. Alshammari, Zeyad M. M. Alenezi

“…The participants were split into two groups: Group A (n = 25) had orthodontic therapy that included expanding the upper jaw and advancing the mandible, whereas Group B (n = 25) acted as the control group and did not get any orthopedic intervention. Prior to and after therapy, the airway dimensions were evaluated using cone beam computed tomography (CBCT) at two time points: baseline and 12 months after treatment. …”
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PEDIATRIC FRACTURES IN A TERTIARY PUBLIC HOSPITAL: WHAT ARE WE DEALING WITH? by Leonardo Lima de Almeida, Edgard Eduard Engel, Jose Batista Volpon

“…Abstract Objective: Orthopedic trauma is significant in modern society due to its incidence and its impact on healthcare and social interactions. …”
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Respiratory dysfunction in whiplash associated disorders (WAD) with cervical plexus syndrome – A case report by NA Nystrom, SR Daulat, A Zakaria, M Petersen, VM Moodley, LP. Champagne

“…In 2019, his condition deteriorated, with significantly increased pain and dyspnea leading to further evaluations that included laboratory studies and consultations with specialists in neurosurgery, neurology, pulmonology, neurophysiology, ENT, general internal medicine, cardiology, radiology, speech pathology, physical medicine, orthopedic surgery, and hand surgery at three separate academic centers in Norway.Eventually, the patient was diagnosed with a condition that is regularly observed among patients referred to our office for evaluation and surgical treatment of chronic, whiplash related pain, and that we propose to label Cervical Plexus Syndrome.One year following exploration and neurolysis of sensory nerves to the right and left superficial cervical plexus, the patient remains pain free, with unimpeded speech and breathing as demonstrated by postoperative spirometry and video recordings.Although the underlying pathophysiology remains unclear, we report what we believe to be the first successful surgical treatment of serious respiratory dysfunction from pain generators in tissue that historically is considered anatomically and functionally separate from the mechanics of breathing. …”
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Preoperative risk assessment and optimization integrating surgical and anesthetic principles and practices: a national survey for internists by Marc-Antoine Lepage, Annie Lecavalier, Gabriele Baldini, Ning-Zi Sun, Amal Bessissow

“…However, they tended to underestimate procedure-specific bleeding risk for general (58%) and orthopedic (76%) surgeries and to overestimate procedure-specific thrombotic risk for vascular (63%) and genitourinary (60%) surgeries. …”
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A Randomized Controlled Trial of the Treatment of Rotator Cuff Tears with Bone Marrow Concentrate and Platelet Products Compared to Exercise Therapy: A Midterm Analysis by Christopher Centeno, Zachary Fausel, Ian Stemper, Ugochi Azuike, Ehren Dodson

“…Patients enrolled into the study were between 18 and 65 years of age presenting to an outpatient orthopedic clinic with partial to full thickness, nonretracted supraspinatus tendon tears. …”
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Complicated caries of permanent teeth in children: status of the problem and modern solution ways by N.S. Proshchenko, H.V. Sorochenko, O.I. Ostapko, O.M. Plyska, Yu.V. Trokhimets

“…The usage of modern technologies of orthopedic dentistry and materials science (3D scanner, 3D printer, T-scan, polymers) will allow to significantly improve the quality of comprehensive treatment and rehabilitation of children with complications of caries of permanent teeth.…”
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