Thermal Development, Mortality, and Fertility of an Apulian Strain of <i>Drosophila suzukii</i> at Different Temperatures by Nuray Baser, Luca Rossini, Gianfranco Anfora, Kürşat Mustafa Temel, Stefania Gualano, Emanuele Garone, Franco Santoro

“…The species successfully developed from egg to adult at 13–29 °C, while between 6–9 and 29–33 °C the development was limited to L2/L3 stages. Optimal temperatures are around 26–28 °C, depending on the life stage. …”
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Contemporary Management of Patients With Chagas Cardiomyopathy in Bolivia by Evan Czulada, BS, Sascha Bercovitch, BA, Yazan Alshawkani, MD, Natalia Noya Weise, MD, Adriana E. Hernani Rodrigo, BS, Ronald Gustavo Durán Saucedo, MD, Marcelo Buhezo Chamón, MD, Robert H. Gilman, MD, David T. Martin, MD

“…Background: Chagas cardiomyopathy (CCM) is the debilitating result of a parasitic infection that causes structural and electrical abnormalities. Yet, optimal CCM management is challenging in the resource-poor communities where it predominates. …”
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Flow Cytometric Assessment of FcγRIIIa-V158F Polymorphisms and NK Cell Mediated ADCC Revealed Reduced NK Cell Functionality in Colorectal Cancer Patients by Phillip Schiele, Stefan Kolling, Stanislav Rosnev, Charlotte Junkuhn, Anna Luzie Walter, Jobst Christian von Einem, Sebastian Stintzing, Wenzel Schöning, Igor Maximilian Sauer, Dominik Paul Modest, Kathrin Heinrich, Lena Weiss, Volker Heinemann, Lars Bullinger, Marco Frentsch, Il-Kang Na

“…Elevated PD1+ NK cell levels, reduced lysis of PDL1-expressing CRC cells and improved NK cell activation in combination with the PDL1-targeting avelumab indicate that the PD1-PDL1 axis contributes to impaired cetuximab-induced NK cell function. Together, these optimized assays effectively identify NK cell dysfunctions in mCRC patients and offer potential for broader application in evaluating NK cell functionality across cancers and therapeutic settings.…”
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Dynamics and associations of selected agrometeorological variables in Robusta growing regions of Uganda by Ronald Ssembajwe, Catherine Mulinde, Saul D. Ddumba, Godfrey H. Kagezi, Ronald Opio, Judith Kobusinge, Frank Mugagga, Yazidi Bamutaze, Anthony Gidudu, Geoffrey Arinaitwe, Mihai Voda

“…Therefore, urgent interventions in form of seasonal schedule restructuring and optimal irrigation use and management to increase productivity especially in areas where CWB is below 0 for over 3 months, offset the increasing VPD and as well effectively manage pest and diseases are recommended.…”
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Impact of thyrotropin levels on outcomes in T1N0M0 papillary thyroid cancer after microwave ablation by Ying Wei, Zhen-Long Zhao, Jie Wu, Shi-Liang Cao, Na Yu, Li-Li Peng, Yan Li, Ming-An Yu

“…However, progression-free survival rates in M-PTC patients showed convergence across all TSH levels by the 5-year follow-up.Conclusion Maintaining TSH levels within the normal range post-ablation may be appropriate for managing T1N0M0 PTC treated with MWA, but randomized controlled trials are needed to confirm optimal TSH targets and their impact on outcomes.…”
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Liver transplantation for homozygous familial hypercholesterolemia: a retrospective analysis from Chinese experience by Hao-Su Zhan, Lin Wei, Wei Qu, Zhi-Gui Zeng, Ying Liu, Yu-Le Tan, Jun Wang, Liang Zhang, En-Hui He, Guang-Peng Zhou, Hai-Ming Zhang, Zhi-Jun Zhu, Li-Ying Sun

“…Method To assess the clinical efficacy, prognosis, and optimal timing of LT for HoFH, a retrospective analysis was conducted on the preoperative, surgical conditions, and postoperative follow-up of children who received an LT for HoFH at the Beijing Friendship Hospital over the period from December 2014 to August 2022. …”
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Synthesis of Fe3O4@MIL-101-OH/Chitosan for adsorption and release of doxorubicin by Iman Najafipour, Nafiseh Emami, Pegah Sadeh, Adonis Amoli, Sareh Mosleh-Shirazi, Ali Mohammad Amani, Hesam Kamyab, Shreeshivadasan Chelliapan, Seyed Reza Kasaee, Ehsan Vafa

“…In this article, the effect of pH, contact time, and drug concentration on DOX adsorption were investigated, and the results showed that at optimal conditions, pH = 8, contact time = 90 min, and drug concentration is 350 ppm, the adsorption capacity of MIL-101-OH/Chitosan and Fe3O4@MIL-101-OH/Chitosan are equal to 185 and 174.3 mg/g. …”
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Exploring the Role of the Pharmacist in the Prevention and Management of Hypertensive Disorders in Pregnancy in Ashanti Region, Ghana by Pauline Boachie‐Ansah, Berko Panyin Anto, Afia Frimpomaa Asare Marfo, Edward Tieru Dassah, Morrison Asiamah, Ivan Eduku Mozu, Nana Ofori Adomako, Kwaku Gyamfi Oppong

“…Prompt management of these disorders is usually recommended to optimize outcomes. Administration of pharmacotherapeutic agents is critical in the prevention and management of these disorders. …”
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Immunological pathogenesis and treatment progress of adenovirus pneumonia in children by Yaowen Liang, Jie Wei, Jianjun Shen, Zihao Liang, Xiuchang Ma, Yuchen Du, Wenxian Qian, Hui Dong, Ping Huang, Apeng Chen, Changhua Yi

“…There are many treatments for adenovirus pneumonia in children, which must be personalized based on a thorough assessment to optimize treatment outcomes. Recent advancements in pharmaceutical development have provided new treatment options for children. …”
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Semaglutide and laparoscopic sleeve gastrectomy in an adolescent with congenital adrenal hyperplasia due to 21-hydroxylase: a case report by Alaina P. Vidmar, Linus Kaiser, Matthew J. Martin, Stuart Abel, Aimee G. Kim, Madeleine Weitzner, Cynthia E. Muñoz, Lynda K. Fisher, Mimi S. Kim, Kamran Samakar

“…The successful outcomes from both pharmacotherapy and bariatric surgery suggest that tailored obesity management strategies can optimize health in this unique population, reinforcing the need for further research into comprehensive obesity care in individuals with congenital adrenal hyperplasia.…”
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Effect of probiotics on the growth, blood profile, and nutritional-metabolic profile of feedlot cattle by Flavia I. Mansilla, María C. Aristimuño Ficoseco, María H. Miranda, Marcela D’Urso Villar, Graciela M. Vignolo, María E. F. Nader-Macías

“…Analysis of clinical parameters showed optimal animal body condition and sensorium state. …”
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A survey of the commercial traits and antioxidant status of goat milk in Mediterranean pastoral farms by Manuel Delgado-Pertiñez, Juan M. Mancilla-Leytón, Eduardo Morales-Jerrett, Sara Muñoz-Vallés, Verónica Cruz, Yolanda Mena

“…The negative correlation between the TAC and the somatic cell count contributes to the important role of antioxidants in maintaining optimal udder health. Vitamin A could be involved in this antioxidant mechanism due to the positive correlation between the TAC and retinol determined in a previous study. …”
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Mapping Susceptibility and Risk of Land Subsidence by Integrating InSAR and Hybrid Machine Learning Models: A Case Study in Xi&#x0027;an, China by Chen Chen, Mimi Peng, Mahdi Motagh, Xinxin Guo, Mengdao Xing, Yinghui Quan

“…In this study, four machine learning models are compared to determine the optimal model, and found that the Random Forest (RF) performs the best in predicting InSAR-derived spatial deformation (Root Mean Square Error = 3.53 mm) and susceptibility (Area Under the Curve = 0.97). …”
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Effect of Fortification with High-Milk-Protein Preparations on Yogurt Quality by Justyna Żulewska, Maria Baranowska, Marika Magdalena Bielecka, Aneta Zofia Dąbrowska, Justyna Tarapata, Katarzyna Kiełczewska, Adriana Łobacz

“…These findings indicate the potential applicability of membrane filtration-derived protein preparations in yogurt production while underscoring the necessity for further investigation to enhance and optimize their sensory characteristics.…”
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Transition to Virtual Care Services during COVID-19 at Canadian Pain Clinics: Survey and Future Recommendations by Victoria Borg Debono, Samuel Neumark, Norman Buckley, Ramesh Zacharias, Eleni Hapidou, Jennifer Anthonypillai, Susy Faria, Carrie-Lynn Meyer, Thomas Carter, Nadia Parker, Brenda Lau, Emmanuel Abreu, Scott Duggan, Etienne Bisson, Josie Pierre, Regina Visca, Patricia Poulin

“…This study aimed to (1) describe and compare the transition from in-person to virtual pain care services at Canadian pain clinics during the onset of the COVID-19 pandemic and (2) provide postpandemic recommendations for pain care services to optimize the quality of patient care. Materials and Methods. …”
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Microclimate monitoring in commercial tomato (Solanum Lycopersicum L.) greenhouse production and its effect on plant growth, yield and fruit quality by Jakub Šalagovič, Dorien Vanhees, Pieter Verboven, Kristof Holsteens, Bert Verlinden, Marlies Huysmans, Bram Van de Poel, Bram Van de Poel, Bart Nicolaï, Bart Nicolaï, Bart Nicolaï

“…These findings could encourage the sector to deploy larger sensor networks for optimal greenhouse climate control. A sensor grid covering the whole area of the greenhouse is a necessity for climate control strategies to mitigate suboptimal conditions.…”
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CFD Modelling of a Centrifugal Compressor with Experimental Validation through Radial Diffuser Static Pressure Measurement by Brett Dewar, Jonna Tiainen, Ahti Jaatinen-Värri, Mike Creamer, Mariana Dotcheva, Jovana Radulovic, James M. Buick

“…The simulation results were also used to investigate the effect of the position (from the blade trailing edge) of the impeller-diffuser interface (a characteristic of the frozen rotor simulation approach). Here an optimal position for the interface was found to be 2% of the blade radius. …”
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Increasing Health Burdens Driven by Global Trade Induced Air Pollution by Ruifei Li, Yu Luo, Xu Zhu, Jin Zhang, Pei Hua, Zhenyu Wang, Wenyu Yang, Qiuwen Chen, Hui Li

“…Accordingly, our findings provide profound suggestions for future policy decisions from different perspectives and demonstrate that optimizing global supply chain through cooperation would mitigate the PM2.5‐related health impacts.…”
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Mitochondrial DNA oxidation and content in different metabolic phenotypes of women with polycystic ovary syndrome by Mailén Rojo, Mailén Rojo, Hernán Pérez, Hernán Pérez, Andrea Liliana Millán, Andrea Liliana Millán, María Constanza Pautasso, Alejandra Duarte, Alejandra Duarte, Giselle Adriana Abruzzese, Alicia Beatriz Motta, Alicia Beatriz Motta, Gustavo Daniel Frechtel, Gustavo Daniel Frechtel, Gustavo Daniel Frechtel, Gloria Edith Cerrone, Gloria Edith Cerrone

“…Additionally, the decline in mtDNA content and the increase in oxidation levels between controls and patients with PCOS lost significance when these relationships were adjusted for the HOMA index.DiscussionThis finding suggests that IR could be the main factor contributing to mitochondrial dysfunction in PCOS. Maintaining optimal mtDNA copies are crucial for mitochondrial and cell function, suggesting potential therapeutic targets for PCOS-associated metabolic disturbances.…”
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Body composition and physical performance of mountain bike athletes by Rayane Carvalho de Moura, Crislane de Moura Costa, Cirley Pinheiro Ferreira, Bruna Lorena Soares Cavalcante Sousa, Leandra Caline dos Santos, Michelly da Silva Pinheiro, Sérgio Luís Galan Ribeiro, Sandro Soares Almeida, Joseline Lima e Silva Pinho, Naíza Monge Lages, Maria Flávia de Sousa, Iago Alves Costa, Glêbia Alexa Cardoso, Acácio Salvador Veras Silva, Alisson Alves Silva, Jefferson Cruz dos Santos Leite, Felipe Machado Brito, Lailson Henrique Oliveira dos Santos, Rubens Lima Rodrigues, Jairo da Costa Souza, Marcos Antonio Pereira dos Santos

“…Understanding these aspects can help optimize training and maximize results. This study aimed to analyze the influence of body composition on physical performance in mountain bike athletes. …”
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