Association between Metrnl and carotid atherosclerosis in patients with type 2 diabetes mellitus by Chunmei Li, Chunmei Li, Qiongzhu Huang, Qiongzhu Huang, Yanqian Zhuang, Yanqian Zhuang, Pin Chen, Pin Chen, Yiyang Lin, Yiyang Lin

“…The ROC curve used to identify the diagnostic accuracy of serum Metrnl level in the predication of T2DM subjects with carotid atherosclerosis revealed an area under the curve (AUC) of 0.742. The optimal cut-off value was 0.61 ng/ml with a sensitivity of 77.6% and a specificity of 58.8%.ConclusionsThis cross-sectional study clearly demonstrated that elevated serum Metrnl level was significantly associated with higher risk of the presence of carotid atherosclerosis. …”
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Assessing the impact of land use and cover change on above-ground carbon storage in subtropical forests: a case study of Zhejiang Province, China by Zihao Huang, Huaqiang Du, Fangjie Mao, Xuejian Li, Guomo Zhou, Jiaqian Sun, Yanxin Xu, Jie Xuan, Yagang Lu, Lei Huang, Meixuan Song

“…We first mapped the land cover patterns using the random forest and spatiotemporal filtering algorithm and then applied these patterns to drive an optimized BIOME-BGC model to simulate the spatiotemporal distribution of AGC density. …”
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Isolation, Characterization, and Safety Evaluation of Human Skin-Derived Precursors from an Adherent Monolayer Culture System by Ru Dai, Wei Hua, Wei Chen, Lidan Xiong, Li Li, Yiming Li

“…Several studies have transcultured human SKPs (termed tSKPs) from fibroblasts (FBs) expanded in monolayer culture. Herein, we optimized the procedure by treating flasks with poly-2-hydroxyethyl methacrylate (poly-HEMA). …”
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Organic iron and iodine in laying hen diet: Performance, egg quality, thyroid hormones, antioxidant status, serum and yolk lipids, and egg iron and iodine contents by Sima Sarlak, Sayed Ali Tabeidian, Majid Toghyani, Amir Davar Foroozandeh Shahraki, Mohammad Goli, Mahmood Habibian

“…Conclusion: It is advisable to enhance the diet with 120 mg.kg-1 of organic iron and 1 mg.kg-1 of organic iodine to ensure optimal performance, egg quality, and overall health in laying hens.…”
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Cerebellar white and gray matter abnormalities in temporal lobe epilepsy: a voxel-based morphometry study by Yini Chen, Jingyu Pan, Andong Lin, Lu Sun, Yufei Li, Hongsen Lin, Renwang Pu, Ying Wang, Yiwei Qi, Bo Sun

“…We used a voxel-based morphometry (VBM) approach utilizing the SUIT toolbox to provide an optimized and fine-grained exploration of cerebellar structural alterations associated with TLE.ResultsCompared with HC, TLE patients showed a significant reduction in the volume of gray matter in the Left lobule VI and white matter in the Right Crus II. …”
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Development of a duplex real-time recombinase aided amplification assay for the simultaneous and rapid detection of PCV3 and PCV4 by Renjie Sun, Hanze Liu, Siqi Sun, Yating Wang, Ying Shan, Xiaoliang Li, Weihuan Fang, Yongle Yang, Ronghui Xie, Lingyan Zhao

“…The assay was completed within 20 min at 39℃ with the designed optimal primers and probes. Results The established assay was more convenient and simpler operation compared with conventional molecular biological assays. …”
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A self-configuration framework for balancing services in the fog of things by Edson Mota, Jurandir Barbosa, Gustavo B. Figueiredo, Maycon Peixoto, Cássio Prazeres

“…Our key contributions include developing the FoT Balance Management service, which dynamically configures and optimizes the distribution of services across the network. …”
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Automatic etiological classification of stroke thrombus digital photographs using a deep learning model by Álvaro Lucero-Garófano, Álvaro Lucero-Garófano, Alicia Aliena-Valero, Isabel Vielba-Gómez, Isabel Vielba-Gómez, Irene Escudero-Martínez, Irene Escudero-Martínez, Lluís Morales-Caba, Lluís Morales-Caba, Fernando Aparici-Robles, Fernando Aparici-Robles, Diana L. Tarruella Hernández, Diana L. Tarruella Hernández, Gerardo Fortea, Gerardo Fortea, José I. Tembl, José I. Tembl, Juan B. Salom, Juan B. Salom, José V. Manjón

“…The segmentation network achieved an average DICE coefficient of 0.96 [SD, 0.13]. The optimal fused imaging and clinical classification network had a 0.968 accuracy [95% CI, 0.935–0.994], and AUC of 0.947 [95% CI, 0.870–1]. …”
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Pioglitazone Attenuates Drug-Eluting Stent-Induced Proinflammatory State in Patients by Blocking Ubiquitination of PPAR by Zhongxia Wang, Tao Zhang, Lizhe Sun, Ruifeng Li, Yuanyuan Wei, Xiaojuan Fan, Zuyi Yuan, Junhui Liu, Tao Chen

“…Twenty-eight patients with coronary artery disease and who underwent DES implantations were randomly assigned to pioglitazone (30 mg/d; PIO) or placebo (control; Con) treatment in addition to optimal standard therapy. After 12 weeks of treatment, plasma concentrations of high-sensitivity C-reactive protein (hs-CRP), interleukin-6 (IL-6), tumor necrosis factor-α (TNF-α), and matrix metalloproteinase-9 (MMP-9) were significantly decreased in PIO group compared to the Con group (P=0.035, 0.011, 0.008, and 0.012, resp.). …”
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Power-free plasma separation based on negative magnetophoresis for rapid biochemical analysis by Lin Zeng, Chao Liu, Yi Yang, Shi Hu, Ruihan Li, Xiaotian Tan, Jienan Shen, Yi Zhang, Shaohui Huang, Hui Yang

“…This innovative device utilizes an advanced long-short alternating double Halbach magnetic array, specifically engineered for optimal magnetic separation. The array’s adaptability allows for seamless integration with separation channels of varying sizes, enabling static separation of whole blood. …”
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A Fine-Grained Aircraft Target Recognition Algorithm for Remote Sensing Images Based on YOLOV8 by Xiao-Nan Jiang, Xiang-Qian Niu, Fan-Lu Wu, Yao Fu, He Bao, Yan-Chao Fan, Yu Zhang, Jun-Yan Pei

“…Finally, a multitype feature fusion is designed, which optimizes the generation of feature maps by integrating local features, high-level semantic information, and low-level texture information, enhancing the accuracy of fine-grained target recognition. …”
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Computer-Aided Construction and Evaluation of Poly-L-Lysine/Hyodeoxycholic Acid Nanoparticles for Hemorrhage and Infection Therapy by Qin Qin, Wenxing Wu, Ling Che, Xing Zhou, Diedie Wu, Xiaohui Li, Yumin Yang, Jie Lou

“…Theoretical simulations and experimental studies were combined to optimize their structure and functionality. In vitro platelet aggregation, antibacterial assays, cytotoxicity tests, and hemolysis evaluations were performed. …”
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Compensation Mechanisms for Early Maturity and High Yield in Tartary Buckwheat (<i>Fagopyrum tataricum</i>): A Study on ‘Source–Sink’ Relationship and Phosphorus Utilization by Xuling Chen, Li Yang, Chunxia Zhao, Shunjiang Zhao, Ziye Meng, Xiaona Zhang, Qijiao Chen, Kesu Wei, Dabing Xiang, Yan Wan, Yu Fan, Yan Wang, Chenggang Liang

“…This study highlights the potential of optimizing the ‘source–sink’ relationship and phosphorus utilization in early-maturing, high-yield Tartary buckwheat breeding.…”
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Oligomerization of Fischer-Tropsch Olefins by Radical Initiation Method for Synthesizing Poly Olefin Base Oils by Yash Vijay Kataria, Vera P. Kashparova, Victor А. Klushin, Olga P. Papeta, Roman E. Yakovenko, Ivan N. Zubkov

“…It was determined that when the oligomerization is carried out in polar solvents such as acetone and dichloromethane the yield of product increases by ~2.1 and ~1.7 times, respectively, while at the same time adding a non-polar solvent such as tetrachloromethane to the reaction mixture decreases the product yield by ~2.0 times. The optimal technological parameters for carrying out oligomerization process of synthetic gasoline and diesel fractions were determined: where azobisisobutyronitrile, content 0.5 wt.%., is used as an initiator, acetone as solvent, with reaction temperature of 200 °C, and duration of 12 hrs. under inert atmosphere. …”
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Neoadjuvant Immunotherapy and De-escalation of Surgery in Locally Advanced Breast Implant-associated Anaplastic Large Cell Lymphoma by Marzia Salgarello, Jaroslaw Krupa, Rebecca Allchin, Simon Pilgrim, Fiona Miall, Arianna Di Napoli, Maurizio Martelli, Giulio Tarantino

“…Due to the complex nature of this disease, a multidisciplinary approach is necessary for optimal management, particularly in locally advanced disease or inoperable patients. …”
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Stapled End-To-Side Ileocolic Anastomosis in Crohn’s Disease: Old Dog, Reliable Tricks? A Retrospective Two-Center Cohort Study by Volkan Doğru, MD, Jean H. Ashburn, MD, Umut Akova, BS, Alton G. Sutter, MD, Eren Esen, MD, Emily M. Gardner, MD, Andre da Luz Moreira, MD, Arman Erkan, MD, John Kirat, MD, Michael J. Grieco, MD, Feza H. Remzi, MD

“…Yet, despite heterogeneous data from different anastomotic configurations, there remains no clear guidance as to the optimal technique. Methods:. In a retrospective cohort design, patients undergoing ileocolic anastomosis in the setting of Crohn’s disease between 2016 and 2021 at two institutions were identified. …”
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Higher incidence of postoperative complications in patients with simultaneous patellar tendon and anterior cruciate ligament ruptures following single surgery: a case series and li... by Hao-ran Su, Xi Gong, Cheng Wang, Hai-jun Wang, Yi-Tian Gao, Jian Wang, Yong Ma, Jian-quan Wang, Wei-li Shi

“…However, due to the limited cases, the design of previous studies was mostly case report with varying conclusions regarding recommended surgical strategy selection, the optimal surgical strategy remains a subject of debate. …”
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Design of a novel Cu-Cr-X alloy with high strength and high electrical conductivity based on mechanical learning by Yunqing Zhu, Yicheng Cao, Lijun Peng, Qian Yu, Zhen Yang, Zengde Li, Junsheng Wu, Haofeng Xie

“…The Cu-Cr-Zr-Mg-Ti alloy with superior properties was optimally designed by genetic algorithm from the massive solutions, which the experimental tensile strength and conductivity reached 668 MPa and 71.5 %IACS, respectively. …”
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Establishment of a prognostic signature and immune infiltration characteristics for uterine corpus endometrial carcinoma based on a disulfidptosis/ferroptosis-associated signature by Yong Huang, Huibin Li, Zhifu Wei, Wanshan He, Bin Chen, Shuang Cheng, Zhifang Zhao, Lv Deng, Lv Deng, Xiaohua Chen, Yu Lin, Yu Lin, Xiaoshan Hong, Xiaoshan Hong

“…Finally, we validated the prognostic gene expression profile in clinical samples.ResultsWe identified five optimal DFRGs that were differentially expressed and associated with the prognosis of uterine corpus endometrial carcinoma (UCEC). …”
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Recent progress in triboelectric platforms: engineering materials to industrial applications from the perspective of manufacturing by Yoonsang Ra, Minjun Song, Donghan Lee, Sunmin Jang, Yu-seop Kim, Joonmin Chae, Sumin Cho, Dongik Kam, Donghyun Lee, Gibeom Lee, Younghoon Lee, Dongwhi Choi

“…Given its unique strength, which includes a diverse material selection and a simple working mechanism, the triboelectric platform can use a variety of manufacturing technologies and the process can be optimized as needed. Numerous research groups have clearly demonstrated the triboelectric platform’s advantages. …”
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