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Correction: The landscape of BRAF transcript and protein variants in human cancer
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22
Epstein-Barr virus reactivation induces divergent abortive, reprogrammed, and host shutoff states by lytic progression.
Published 2024-10-01“…These data reveal previously unknown and promiscuous outcomes of lytic reactivation with broad implications for viral replication and EBV-associated oncogenesis.…”
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23
Host factor PLAC8 is required for pancreas infection by SARS-CoV-2
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24
Bases evolutivas y ecológicas de la carcinogénesis humana ¿cuestión de mala suerte?
Published 2018-01-01“…De hecho, la oncogénesis adaptativa incluso puede ser extendida al nivel del "macroambiente" poblacional y social. …”
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25
Chimeric RNA in Cancer and Stem Cell Differentiation
Published 2018-01-01“…They have demonstrated importance in normal cell physiology, and their dysregulation can induce oncogenesis and impact cell differentiation. In this review, we outline proven mechanisms through which intergenically spliced chimeric RNAs are involved in carcinogenesis. …”
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26
HPV and head and neck cancer: A comprehensive review
Published 2024-06-01“…The following is a narrative review of mechanism of oncogenesis by HPV, diagnosis, comparison of the prognosis and clinical features between HPV positive and negative cases, histological features and finally a brief overview of the management options of HPV positive cancers.…”
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27
A Role for RNA Viruses in the Pathogenesis of Burkitt's Lymphoma: The Need for Reappraisal
Published 2012-01-01“…The Flavivirus, Hepatitis C, a Class 1 Human Carcinogen, closely related to the arboviruses, Yellow Fever, and Dengue, is also more distantly related to Chikungunya Virus. The mechanisms of oncogenesis believed to operate in Hepatitis C lymphomagenesis are discussed, as is their potential applicability to Chikungunya Virus.…”
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28
Centrosome amplification and aneuploidy driven by the HIV-1-induced Vpr•VprBP•Plk4 complex in CD4+ T cells
Published 2024-03-01“…We propose that the Vpr•VprBP•Plk4 complex serves as a molecular link that connects HIV-1 infection to oncogenesis and that inhibiting the Vpr C-terminal motif may reduce the occurrence of HIV-1-associated cancers.…”
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T Cells in Gastric Cancer: Friends or Foes
Published 2012-01-01“…Unfortunately T cells, instead of protecting from the onset of cancer, can contribute to oncogenesis. Herein we review the different types, “friend or foe”, of T-cell response in gastric cancer.…”
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30
Epigenetic and epitranscriptomic regulation during oncogenic γ-herpesvirus infection
Published 2025-01-01“…Oncogenic gamma herpesviruses, including Epstein–Barr Virus (EBV) and Kaposi’s Sarcoma-associated Herpesvirus (KSHV), are opportunistic cancer-causing viruses and induces oncogenesis through complex mechanisms, which involves manipulation of cellular physiology as well as epigenetic and epitranscriptomic reprogramming. …”
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31
Modeling Cancer in HIV-1 Infected Individuals: Equilibria, Cycles and Chaotic Behavior
Published 2006-01-01“…Gaining insight into the epidemiology and mechanisms that underlieAIDS-related cancers can provide us with a better understanding of cancer immunity and viral oncogenesis. In this paper, an HIV-1 dynamicalmodel incorporating the AIDS-related cancer cells was studied. …”
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32
Molecular Pathogenesis of MALT Lymphoma
Published 2015-01-01“…There is now increasing evidence suggesting that the oncogenic product of translocation cooperates with immunological stimulation in oncogenesis, that is, the association with chronic bacterial infection or autoaggressive process. …”
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33
Ensuring the Stability of the Genome: DNA Damage Checkpoints
Published 2001-01-01“…An examination of this research, with emphasis on the function of checkpoint proteins, their relationship to DNA repair, and their involvement in oncogenesis is undertaken here.…”
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The amount of DNA and RNA in primary cancer cells and their metastases
Published 2024-08-01“…Considering the significant impact of oncopathology on global morbidity and mortality, as well as changes in its prevalence and typology, research into the molecular-genetic mechanisms of oncogenesis and metastasis, particularly the role of nucleic acids, becomes crucial. …”
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Stochastic modelling of PTEN regulation in brain tumors: A model for glioblastoma multiforme
Published 2015-05-01“…This work is the outcome of the partnership between the mathematical group of Department DISBEF and the biochemical group of Department DISB of the University of Urbino "Carlo Bo" in order to better understand some crucial aspects of brain cancer oncogenesis.Throughout our collaboration we discovered that biochemists are mainly attracted to the instantaneous behaviour of the whole cell, while mathematicians are mostly interested in the evolution along time of small and different parts of it. …”
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Multiple Factors Determine the Oncolytic or Carcinogenic Effects of TLRs Activation in Cancer
Published 2024-01-01“…In this review, the potential therapeutic value of TLRs in immunotherapy and its role in oncogenesis are explored. The emerging use of artificial intelligence is mentioned.…”
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BCL6 (B-cell lymphoma 6) expression in adenomyosis, leiomyomas and normal myometrium.
Published 2025-01-01“…The BCL6 protein, a transcriptional repressor implicated in cell proliferation and oncogenesis, has been linked to the pathogenesis of endometriosis. …”
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38
Assessment of Hsp90β-selective inhibitor safety and on-target effects
Published 2025-01-01“…Abstract The heat shock protein 90 (Hsp90) family of molecular chaperones mediates the folding and activation of ~ 400 client proteins, many of which contribute to oncogenesis. As a result, Hsp90 pan-inhibitors, which inhibit all four Hsp90 isoforms, have been investigated in the clinic for the treatment of cancer. …”
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Peripheral membrane protein endophilin B1 probes, perturbs and permeabilizes lipid bilayers
Published 2025-02-01“…BAR protein endophilin B1 plays a key role in multiple cellular processes critical for oncogenesis, including autophagy and apoptosis. Amphipathic regions in endophilin B1 drive membrane association and tubulation through membrane scaffolding. …”
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Elevated expression of ANTXR1 gene in tumors is a poor prognostic biomarker for patients with bladder cancer
Published 2025-01-01“…In addition to the various roles TEM8 plays in oncogenesis, including angiogenesis, epithelial-to-mesenchymal transition, and cell migration, it has also been shown that the overexpression of the ANTXR1 gene in solid tumors correlates with poor prognostic indicators in several solid tumor histologies. …”
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