Prevalence and determinants of post-neonatal mortality in East Africa: a multilevel analysis of the recent demographic and health survey by Alebachew Ferede Zegeye, Desale Bihonegn Asmamaw, Wubshet D. Negash, Wubshet D. Negash, Tadele Biresaw Belachew, Elsa Awoke Fentie, Atitegeb Abera Kidie, Tsegaw Amare Baykeda, Samrawit Mihret Fetene, Banchlay Addis, Sisay Maru Wubante, Abel Endawkie, Tadesse Tarik Tamir

“…The data were interpreted using the adjusted odds ratio (AOR) and confidence interval (CI). The best-fit model has been found to be the one with the lowest deviance and highest logliklihood ratio.ResultsIn East Africa, post-neonatal mortality was found to be 15 per 1,000 live births. …”
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The impact of pre-transplant ventricular assist device support in pediatric patients with end-stage heart failure on the outcomes of heart transplantation—“a single center experien... by L. Lily Rosenthal, L. Lily Rosenthal, L. Lily Rosenthal, Carola Grinninger, Sarah Marie Ulrich, Robert Dalla Pozza, Nikolaus A. Haas, Paolo Brenner, Michael Schmoeckel, Sebastian Michel, Sebastian Michel, Sebastian Michel, Christian Hagl, Christian Hagl, Jürgen Hörer, Jürgen Hörer, Jürgen Hörer

“…Early primary-graft-failure was 10% in group 1 and 13% in group 2. Odds ratio [OR] is as follows: 1.992, 95% confidence interval [CI]: 0.983–1.007, p = 0.266, aortic clamp time per minutes: OR: 1.008, 95% CI: (0.997–1.019), p = 0.164, HLM time per minutes: OR: 0.996, 95% CI: (0.991–1.001), p = 0.146, Operation time per minutes: OR: 1.000, 95% CI: (0.995–1.004), p = 0.861.ConclusionThe provision of pre-HTx VAD support does not have an adverse effect on the short- and long-term survival of pediatric patients undergoing HTx. …”
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The diagnostic performance of International Ovarian Tumor Analysis: Simple Rules for diagnosing ovarian tumors—a systematic review and meta-analysis by Awadia Gareeballah, Moawia Gameraddin, Moawia Gameraddin, Sultan Abdulwadoud Alshoabi, Amirah Alsaedi, Maisa Elzaki, Walaa Alsharif, Ibrahim Mohamed Daoud, Ibrahim Mohamed Daoud, Shrooq Aldahery, Magbool Alelyani, Elrashed AbdElrahim, Fahad H. Alhazmi, Zuhal Y. Hamd, Raga Ahmed Abouraida, Mayeen Uddin Khandaker, Mayeen Uddin Khandaker, Mayeen Uddin Khandaker, Mohamed Adam

“…After estimating the pooled effect of the sensitivity, specificity, and diagnostic odds ratio (DOR), the summary receiver operating characteristic (SROC) curve was estimated using the bivariate random effects model. …”
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Impact of Late Ventricular Arrhythmias on Cardiac Mortality in Patients with Acute Myocardial Infarction by Takuma Takada, Koki Shishido, Takahiro Hayashi, Shohei Yokota, Hirokazu Miyashita, Hiroaki Yokoyama, Takashi Nishimoto, Tomoki Ochiai, Noriaki Moriyama, Kazuki Tobita, Shingo Mizuno, Futoshi Yamanaka, Masato Murakami, Yutaka Tanaka, Saeko Takahashi, Shigeru Saito

“…Moreover, independent predictors of in-hospital cardiac mortality among patients with AMI who had sustained VT/VF were higher peak CK-MB [Odds ratio (OR: 1.001, 95%confidence interval (CI): 1.000-1.002, p= 0.03)], higher Killip class (OR: 1.484, 95%CI 1.017-2.165, p= 0.04), and late VT/VF (OR: 3.436, 95%CI 1.115-10.59, p= 0.03). …”
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Prevalence and clinical profile of comorbidity among newly diagnosed pulmonary tuberculosis patients: a multi-center observational study in eastern China by Wei Wang, Wei Wang, Xiaomeng Wang, Xiaomeng Wang, Songhua Chen, Jun Li, Qinglin Cheng, Yu Zhang, Qian Wu, Qian Wu, Kui Liu, Kui Liu, Xuli Jiang, Bin Chen, Bin Chen

“…Compared to patients without comorbidities, patients with diabetes mellitus (adjusted odds ratio [AOR]: 2.88, 95% confidence interval [CI]: 2.42–3.43) were more likely to show cavities in chest X-ray, while patients with pleuritis (AOR: 0.27, 95% CI: 0.23–0.32), other extrapulmonary tuberculosis (AOR: 0.48, 95% CI: 0.36–0.64), and tracheobronchial tuberculosis (AOR: 0.40–0.79) were less likely to show chest cavities in X-ray. …”
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Analysis of the risk of oncological adverse events associated with infliximab in combination with azathioprine compared to monotherapy: insights from the FAERS database by Qian Qiao, Qian Qiao, Qian Qiao, Jiachen Sun, Jiachen Sun, Jiachen Sun, Ya Zheng, Ya Zheng, Yingying Mi, Yingying Mi, Yingying Mi, Yanan Gong, Yanan Gong, Jiahui Liu, Jiahui Liu, Jiahui Liu, Wenyue Rui, Wenyue Rui, Wenyue Rui, Yumei Ma, Yumei Ma, Yumei Ma, Yongning Zhou, Yongning Zhou, Min Liu, Min Liu

“…Signal mining employed methods such as Reported Odds Ratio (ROR), Proportional Reporting Ratio (PRR), Multiple Gamma-Poisson Scaling Assessment (MGPSA) and Bayesian Confidence Interval Progressive Neural Network (BCPNN).ResultsOur analysis of the FAERS database revealed that the highest number of reported cases involved skin-related tumors, both individually and in combination. …”
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Prognostic and diagnostic value of circRNA expression in cervical cancer: a meta analysis by Yi Xu, Yi Xu, Changxia Li, Changxia Li, Lifang Cheng, Shaoheng Wang, Yuqing Wu, Shiyang Li, Mingqiang Liu, Xiaohua Tao

“…The importance of circRNAs was further evaluated in terms of clinical relevance, pathological features, and prognostic value using pooled odds ratios (ORs) and hazard ratios (HRs).ResultsThe meta-analysis included 27 studies, which were categorised based on diagnostic applications (n=3), clinicopathological correlations (n=15), and prognostic evaluations (n=23). …”
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Toxoplasma gondii in dromedary camels (Camelus dromedarius) in Egypt: a comparative seroepidemiological study in Upper and Lower Egypt by Ehab Kotb Elmahallawy, Ehab Kotb Elmahallawy, Nady Khairy Elbarbary, David Cano-Terriza, David Cano-Terriza, Tomás Fajardo, Nada Oudah Albalawi, Débora Jiménez-Martín, Marwa M. I. Ghallab, Ahmed Gareh, Refaat Ras, Refaat Ras, Isabelle Villena, Sabry A. S. Sadek, Hajar AlQadeeb, Hind Alzaylaee, Sonia Almería, Ignacio García-Bocanegra, Ignacio García-Bocanegra

“…Thus, camels from Lower Egypt had significantly higher seroprevalence of T. gondii (19.92%, 51/256) compared to those from Upper Egypt (7.78%; 20/257; p < 0.001; odds ratio [OR] = 2.94; 95% CI: 1.70–5.10). Our results provide evidence of moderate, widespread, and heterogeneous spatial distribution of T. gondii among camel populations in Egypt, which might have important implications for animal and public health in that country. …”
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Knowledge towards health impacts of climate change among Amhara Sayint community, Northeastern Ethiopia by Genanew Mulugeta Kassaw, Asmamaw Malede, Adinew Gizeyatu, Metadel Adane, Asha Embrandiri, Awoke Keleb, Gete Berihun, Abebe Kassa Geto, Belachew Tekleyohannes Wogayehu, Gebremeskel Kibret Abebe, Tibebu Habtie Zewde, Sisay Abebe Debela, Solomon Seyoum, Amana Ogeto Luke, Gashaw Wondaya, Atitegeb Abera Kide, Mekonnen Moges, Denise Metoyer, Mesfin Gebrehiwot

“…Proportional odds model analysis result indicated that gender (female) (adjusted odds ratio [AOR] = 1.49; 95% CI: 1.053, 2.13), wealth status (poorest) (AOR = 1.97; 95% CI: 1.01, 3.83), educational status (unable to read and write) (AOR = 4.13; 95% CI: 1.25, 13.68) and participation status in environmental protection activities (not) (AOR = 1.78; 95% CI: 1.17, 2.71) were factors that significantly associated with inadequate and medium levels of knowledge towards the health impacts of climate change. …”
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Association between solid cooking fuels exposure and metabolic syndrome: Evidence from China by Jiaming Xue, Shuai Chen, Yicheng Jiang, Qi Liu, Yu Wang, Yuwen Jiao, Yuancheng Shao, Jie Zhao, Yan Zhou, Dongmei Wang, Liming Tang

“…Through cross-sectional and longitudinal studies, we found that the use of solid fuels reduced the risk of MetS in participants compared with clean fuels (cross-sectional study: 2011: Odds ratio (OR): 0.819, 95 %confidence interval (CI): 0.747–0.897, P < 0.001; 2015: OR: 0.766, 95 %CI: 0.708–0.851, P < 0.001; longitudinal study: OR: 0.736, 95 %CI: 0.652–0.831, P < 0.001).This impact ceases to exist whenever a switch in fuel type occurs (Non persistent clean: OR: 0.937, 95 %CI: 0.837–1.050, P = 0.262; Persistent solid: OR: 0.767, 95 %CI: 0.691–0.853, P < 0.001). …”
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Prevalence and determinants of unintended pregnancy among rural reproductive age women in Ethiopia by Melak Jejaw, Kaleb Assegid Demissie, Misganaw Guadie Tiruneh, Kaleab Mesfin Abera, Yawkal Tsega, Abel Endawkie, Wubshet D. Negash, Amare Mesfin Workie, Lamrot Yohannes, Mihret Getnet, Nigusu Worku, Adina Yeshambel Belay, Lakew Asmare, Hiwot Tadesse Alemu, Demiss Mulatu Geberu, Asebe Hagos

“…Variables significantly associated with unintended pregnancy were declared at p-value < 0.05 with adjusted odds ratio and 95% confidence interval (CI). The prevalence of unintended pregnancy in rural women was 31.66% ( 95%CI 28.8%, 34.66%). …”
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Neurotrophin-3 as a mediator in the link between PM2.5 exposure and psychiatric disorders: A Mendelian randomization study by Yuan Zhang, Wei Wang, Xuening Zhang, Ran Jing, Xin Wen, Peng Xiao, Xinjie Liu, Zengle Zhao, Tongmin Chang, Yufei Li, Wen Liu, Chenxi Sun, Xiaorong Yang, Lejin Yang, Ming Lu

“…Results: Our findings indicated that PM2.5 was positively associated with major depressive disorder (odds ratio (OR): 1.33, 95 % confidence interval (CI): 1.11–1.55), anxiety disorder (OR: 2.96, 95 % CI: 2.13–3.79), schizophrenia (OR: 1.55, 95 % CI: 1.29–1.81), and attention deficit hyperactivity disorder (ADHD) (OR: 1.95, 95 % CI: 1.66–2.24). …”
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Renal function and clinical outcomes in survivors of out-of-hospital cardiac arrest by Hao-Wei Lee, Ming-Jen Kuo, Pai-Feng Hsu, I-Hsin Lee, Chih-Yu Yang, Teh-Fu Hsu, Chorng-Kuang How, Yenn-Jiang Lin, Chin-Chou Huang

“…Multivariable analysis using regression models revealed that unfavorable neurological outcomes at discharge and higher mortality at 2 years were associated with AKI (odds ratio [OR] 7.684, 95% confidence interval (CI) 2.683–22.010, P < 0.001; hazard ratio [HR] 2.159, 95% CI 1.272–3.664, P = 0.004), AKI without recovery (OR 5.275, 95% CI 2.049–13.583, P < 0.001; HR 5.470, 95% CI 3.304–9.862, P < 0.001), and impaired pre-discharge renal function (OR 3.164, 95% CI 1.442–6.940, P = 0.004; HR 2.876, 95% CI 1.861–4.443, P < 0.001). …”
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Inter-pregnancy interval and uterine rupture during a trial of labour after one previous caesarean delivery and no previous vaginal births: a retrospective population-based cohort... by Pejman Adily, Travis Bettison, Mark Lauer, Rajit Narayan, Adam Mackie, Hala Phipps, Vincenzo Berghella, Marjan M. Haghighi, Katelyn Perren, George Johnson, Bradley de Vries

“…Findings: We examined 491,998 trials of labour among parturients with one previous livebirth by caesarean delivery and no previous vaginal births. The odds ratio (OR) of uterine rupture per three months interpregnancy interval was 0.91 (95% CI 0.88–0.94) between zero and 21 months after adjusting for confounders, with no further change in risk detected beyond 21 months. …”
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Clonal hematopoiesis of indeterminate potential is a risk factor of gastric cancer: A Prospective Cohort in UK Biobank study by Zhihui Xi, Huolun Feng, Kunling Chen, Xin Guo, Dandan Zhu, Jiabin Zheng, Yong Li

“…Main outcomes and measures: Odds ratio (OR) of CHIP with gastric cancer risk was estimated using multivariable logistic regression models. …”
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Abnormal Liver Tests during Hospitalization Predict Mortality in Patients with COVID-19: A Multicenter Study from South America by Domingo Balderramo, Angelo Z. Mattos, Victoria Mulqui, Talita Chiesa, Zuly Plácido-Damián, Jaysoom Abarca, Andrea Bolomo, Yanina Carlino, Isadora Z. Bombassaro, Denusa Wiltgen, Laura Tenorio Castillo, Karina Díaz, Johana Acuña, Estela Manero, Jhon Prieto, Enrique Carrera, Javier Díaz-Ferrer, Jose D. Debes

“…ALEx2 on admission was present in 87 (29.2%) patients and was found to be independently associated with 1-week mortality (odds ratio (OR) = 3.55; 95% confidence interval (95%CI) 1.05–12.05). …”
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Association Between Gastrointestinal-Related Quality of Life and Frailty Using Baseline Data of the Prospective Cohort Study (JUSTICE-TOKYO Study) by Daisuke Asaoka, Osamu Nomura, Koji Sugano, Kei Matsuno, Hiroyuki Inoshita, Nobuto Shibata, Hideki Sugiyama, Noemi Endo, Yoshiyuki Iwase, Miyuki Tajima, Naoko Sakuma, Megumi Inoue, Mariko Nagata, Taeko Mizutani, Mizuki Ishii, Sachi Iida, Yoshiko Miura, Yuji Nishizaki, Naotake Yanagisawa, Tsutomu Takeda, Akihito Nagahara, Katsumi Miyauchi

“…The multivariate analysis revealed that age (odds ratio [OR]: 1.070, <i>p</i> < 0.001), QOL (OR: 0.982, <i>p</i> = 0.009), a history of falls (OR: 1.702, <i>p</i> = 0.029), sarcopenia (OR: 4.708, <i>p</i> < 0.001), steroid use (OR: 3.741, <i>p</i> = 0.001), analgesic drug use (OR: 2.056, <i>p</i> = 0.014), Mini Mental State Examination (OR: 0.915, <i>p</i> = 0.011), Geriatric Depression Scale 15 (OR: 1.101, <i>p</i> = 0.008), fullness-related QOL score (OR: 1.119, <i>p</i> = 0.010), chronic obstructive pulmonary disease assessment test (OR: 1.048, <i>p</i> = 0.007), and 10-item Eating Assessment Tool (OR: 1.071, <i>p</i> = 0.009) were related to frailty. …”
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Viral load suppression rate of third-line antiretroviral therapy and its association with gender among HIV patients after second-line treatment failure in Africa: a systematic revi... by Tilahun Degu Tsega, Sintayehu Simie Tsega, Asaye Alamneh Gebeyehu, Getaneh Atikilt Yemata, Rahel Mulatie Anteneh, Almaw Genet Yeshiwas, Getasew Yirdaw, Chalachew Yenew, Anley Shiferaw Enawgaw, Amare Genetu Ejigu, Ahmed Fentaw Ahmed, Zeamanuel Anteneh Yigzaw, Berhanu Abebaw Mekonnen, Meron Asmamaw Alemayehu, Abathun Temesgen, Abebaw Molla, Habitamu Mekonen, Assefa Andargie Kassa, Gashaw Melkie Bayeh

“…Meta-regression, subgroup and sensitivity analyses were also performed. The odds ratio with a 95% confidence interval was used to assess the association of gender with the viral load suppression rate in patients on third-line antiretroviral therapy. …”
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Determinants of the Continuum of Maternal Healthcare Services in Northwest Ethiopia: Findings from the Primary Health Care Project by Asmamaw Atnafu, Adane Kebede, Bisrat Misganaw, Destaw Fetene Teshome, Gashaw Andargie Biks, Getu Debalkie Demissie, Haileab Fekadu Wolde, Kassahun Alemu Gelaye, Mezgebu Yitayal, Tadesse Awoke Ayele, Telake Azale, Terefe Derso, Tsegaye Gebremedhin, Endalkachew Dellie

“…Bivariable and multivariable logistic regression analysis were computed, and in the multivariable logistic regression analysis, adjusted odds ratio (AOR) with 95% confidence interval (CI) and a p value of less than 0.05 were used to identify the associated factors with completion of the continuum of maternal healthcare services. …”
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Associations between Osteocalcin, Calciotropic Hormones, and Energy Metabolism in a Cohort of Chinese Postmenopausal Women: Peking Vertebral Fracture Study by Ruizhi Jiajue, Shuying Liu, Yu Pei, Xuan Qi, Yan Jiang, Qiuping Wang, Wenbo Wang, Xiran Wang, Wei Huang, Xin Zheng, Zhiwei Ning, Ou Wang, Mei Li, Xiaoping Xing, Wei Yu, Ling Xu, Weibo Xia

“…In the logistic regression model, both OC and PTH were negatively associated with the prevalence of diabetes (odds ratio [OR], 95% confidence interval [95% CI]: 0.967, 0.948–0.986 for OC and 0.986, 0.978–0.994 for PTH). …”
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