Acetylation of proximal cysteine-lysine pairs by alcohol metabolism by Courtney D. McGinnis, Peter S. Harris, Brenton I.M. Graham, John O. Marentette, Cole R. Michel, Laura M. Saba, Richard Reisdorph, James R. Roede, Kristofer S. Fritz

“…Our analysis revealed that alcohol metabolism induces redox changes and acetylation selectively on proximal Cys-Lys pairs with an odds ratio of 1.88 (p < 0.0001). Key Cys-Lys redox signaling hubs were impacted in metabolic pathways associated with ALD, including lipid metabolism and the electron transport chain. …”
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Effect of differences in vascular anatomy on surgical outcomes of left pancreatectomy: a retrospective study by Masahiro Fukada, Noriki Mitsui, Takeshi Horaguchi, Yuji Hatanaka, Itaru Yasufuku, Yuta Sato, Jesse Yu Tajima, Shigeru Kiyama, Yoshihiro Tanaka, Katsutoshi Murase, Nobuhisa Matsuhashi

“…In all LP cases, the pancreatic resection line (above the portal vein: odds ratio [OR] 3.47; 95% confidence interval [CI] 1.69–11.18; p < 0.01), the SpA type (type 2; OR 2.77; 95% CI 1.16–6.94; p = 0.02), and surgery type (MIS; OR 5.24; 95% CI 2.17–14.00; p < 0.001) were independently associated with prolonged operation times. …”
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Exploring the potential association between serum selenium and hypertension in obese adult males in the United States by Bei Li, Haiyan Ma, Ying Yu, Jieli Chen, Shengnan He, Lan Yang

“…After rigorous adjustment for sociodemographic, physical, and laboratory test covariates, the weighted odds ratio (OR) of hypertension increased by 103% for every 1 standard deviation (SD) increase (approximately 24.41 µg) in the serum selenium concentration in participants assigned to the highest serum selenium group (weighted OR = 2.03; 95% CI = 1.24–3.32; P = 0.013). …”
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Clinical and molecular analysis of JCPyV and BKPyV infection and associated risk of urothelial carcinoma development in the upper tract by Chun-Nun Chao, Chi-Feng Hung, Wei‑Hong Lai, Chun-Liang Tung, Wan-Yun Yeh, Kai-Wu Yang, Meilin Wang, Ya-Yan Lai, Pei-Lain Chen, Cheng-Huang Shen

“…JCPyV infection and LT protein expression increased the odds ratio (OR) of UTUC by 9.13-fold. The OR of UTUC was higher by 10.34-fold in patients with mutant p53 and by 10.37-fold in those with simultaneous LT and mutant p53 expression. …”
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Clinical characteristics, etiology, and treatment of young adult‐onset epilepsy: A 24‐year retrospective study by Xu Zhang, Feng Xiang, Ziyu Wang, Yang Li, Chenjing Shao, Xiaoyang Lan, Senyang Lang, Xiangqing Wang

“…Multifactorial regression analysis showed that the factors associated with poor seizure control included longer seizure duration (odds ratio [OR] 1.85; 95% confidence interval [CI] 1.58‐2.16; p < 0.001), electroencephalography (EEG) epileptic discharge (OR 1.37; 95% CI 1.17–1.67; p < 0.001), focal seizure (OR 1.69; 95% CI 1.38–2.07; p < 0.001), and seizure clusters (OR 3.35; 95% CI 2.70–4.15; p < 0.001). …”
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Regulatory problems and developmental psychopathology within the first 2 years of living—a nested in cohort population-based study by Janni Ammitzbøll, Janni Ammitzbøll, Anne Lise Olsen, Susanne Landorph, Christian Ritz, Anne Mette Skovgaard, Anne Mette Skovgaard

“…Data analyses included logistic regression models and analyses of the mediation effect of maternal mental health and relationship problems.ResultsRP of sleep were associated with a 2-fold increased risk of child mental disorder specifically sleep disorders, adjusted odds ratio (OR) 9.3 [95% confidence interval (CI): 2.0–42.9], disorders of behavior and emotions, adjusted OR 2.9 (95% CI: 1.0–8.4), and DC:0-3R regulatory disorders, adjusted OR 2.7 (95% CI: 1.0–7.5). …”
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Factors associated with early hospital readmission for acute decompensation of cirrhosis - prospective cohort study by Tamara Liana Zocche, Cláudia Maccali, Fernanda Cristina de Augustinho, Elayne Cristina de Morais Rateke, Camila Matiollo, Ariane Borgonovo Rayes, Dariana Carla Maggi, Esther Buzaglo Dantas-Corrêa, Leonardo de Lucca Schiavon, Janaina Luz Narciso-Schiavon

“…In the logistic regression analysis, CLIF-SOFA variables (odds ratio [OR] 1.137, 95% confidence interval [CI] 1.003–1.289, p=0.045) and several complications present in the initial hospitalization (OR 1.503, 95% CI 1.074–2.105, p=0.018) independent of early readmission. …”
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Safety evaluation of medroxyprogesterone acetate: a pharmacovigilance analysis using FDA adverse event reporting system data by Luyang Su, Ren Xu, Yanan Ren, Shixia Zhao, Weilan Liu, Zeqing Du

“…Disproportionality analyses were conducted using several statistical methods, including reporting odds ratio (ROR), proportional reporting ratio (PRR), empirical Bayesian geometric mean (EBGM). …”
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Transforming Growth Factor-β Protects against Inflammation-Related Atherosclerosis in South African CKD Patients by Muzamil Olamide Hassan, Raquel Duarte, Therese Dix-Peek, Caroline Dickens, Sagren Naidoo, Ahmed Vachiat, Sacha Grinter, Pravin Manga, Saraladevi Naicker

“…In multiple logistic regression, age, TGF-β2, and TGF-β3 were the only independent predictors of subclinical atherosclerosis in CKD patients [age: odds ratio (OR), 1.054; 95% confidence interval (CI): 1.003 – 1.109, p=0.039; TGF-β2: OR, 0.996; 95% CI: 0.994–0.999, p=0.018; TGF-β3: OR, 0.992; 95% CI: 0.985–0.999, p=0.029). …”
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The impact of the National Syphilis Prevention Program on the prevalence of syphilis among people living with HIV in China: a systematic review and meta‐analysis by Qingling Zeng, Yuhui Yang, Limin Zhang, Jiangyu Yan, Jian Wang, Jingmin Nie, Qingmei Wang, Yu Luo, Gaoming Li

“…The prevalence of syphilis was significantly higher in men living with HIV than in women living with HIV (pooled odds ratio 1.67, 95% CI 1.29–2.15), with the highest prevalence in the eastern region (2.55, 95% CI 1.80–3.59). …”
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Patterns of general and abdominal obesity and their association with hypertension control in the iranian hypertensive population: insights from a nationwide study by Fataneh Esmaeili, Keyvan Karimi, Samaneh Akbarpour, Mohammadreza Naderian, Shirin Djalalinia, Ozra Tabatabaei-Malazy, Ali Golestani, Nazila Rezaei

“…Compared to normal weight, underweight (adjusted odds ratio [AOR] = 0.94, 95% CI: 0.57–1.56), overweight (1.37 [1.16–1.61]), and general obesity (1.47 [1.24–1.75]) were associated to uncontrolled HTN compared to normal weight. …”
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Silent cerebral lesions after catheter ablation for atrial fibrillation using cryoballoon, hotballoon, laserballoon and radiofrequency catheters: a Bayesian network meta-analysis by Tiantian Zheng, Youjin Kong, Li Wu, Chenxia Wu, Chenxia Wu, Wei Mao, Wei Mao, Xinbin Zhou, Xinbin Zhou

“…Laserballoon ablation (LBA) had a higher incidence of SCLs than cryoballoon ablation (CBA) [odds ratio [OR] = 1.86, 95% confidence interval [CI] 1.06–3.27, p = 0.032] in the PMA, while no significant difference was detected between the CA techniques according to the NMA. …”
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Discriminant analysis of occupational performance characteristics in patients with major depressive disorders and healthy individuals by Tomonari Hayasaka, Izumi Nagashima, Miku Hoshino, Koji Teruya, Yasuyuki Matumoto, Masami Murao, Taku Maruki, Masako Watanabe, Takeshi Katagiri, Yayoi Imamura, Mariko Kurihara, Yuki Oe, Yoshikazu Takaesu, Takashi Tsuboi, Koichiro Watanabe, Hitoshi Sakurai

“…Key discriminators included “Ask questions and consult” (p < 0.001, odds ratio [OR] = 0.051, 95% confidence interval [CI] = 0.009–0.283), “Concentrate on work” (p = 0.003, OR = 0.078, 95% CI = 0.015–0.416), “Choose simple work” (p = 0.004, OR = 17.803, 95% CI = 2.446–129.597), and “Punctual” (p = 0.017, OR = 0.030, 95% CI = 0.002–0.530). …”
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A Systematic Review and Meta-analysis of Randomized Controlled Trials on Comparing Transabdominal Preperitoneal Versus Lichtenstein Operations for Primary Inguinal Hernia Repair by Muhammad Aslam Javed, Muhammad Arshad Abbas, Mudassar Murtaza, Wasif Majeed Chaudhry, Adnan Faisal, Muhammad Mohsin Gillani

“…The overall complication rate was lower for the TAPP group (Odds Ratio = 0.461) as compared to Lichtenstein repair. …”
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Knowledge, attitudes and practices of oral HIV pre-exposure prophylaxis (PrEP) among healthcare workers in the Ekurhuleni District, South Africa by E Mahlare, E Ramutshila, A Musekiwa, L Kuonza, T Mabuto

“…Participants who were aged >50 years had poor HIV PrEP knowledge (adjusted odds ratio (aOR) 0.1; 95% confidence interval (CI) 0.0 - 0.4; p=0.01) compared with participants <30 years old. …”
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Oxidative balance score was negatively associated with the risk of metabolic syndrome, metabolic syndrome severity, and all-cause mortality of patients with metabolic syndrome by Zhixiao Xu, Xiong Lei, Weiwei Chu, Luoqi Weng, Chengshui Chen, Chengshui Chen, Chengshui Chen, Ran Ye

“…The OBS (where a higher OBS signified an increased prevalence of anti- or pro-oxidant exposures) weighed the 20 factors, while the MetS severity score weighed the five factors.ResultsAfter multivariable adjustment, individuals with elevated OBS were found to exhibit a decreased susceptibility to MetS [odds ratio (OR) 0.95; 95% CI 0.94-0.96]. The adjusted OR was 0.42 (95% CI 0.33-0.53) for MetS risk in the fourth OBS quartile compared with those in the first OBS quartile (P for trend &lt; 0.001). …”
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Prevalence and Determinants of Diarrheal Diseases among Under-Five Children in Horo Guduru Wollega Zone, Oromia Region, Western Ethiopia: A Community-Based Cross-Sectional Study by Kefalew Alemayehu, Lemessa Oljira, Melake Demena, Abdi Birhanu, Dasselegn Workineh

“…Binary logistic regression was used to assess the association of the diarrheal diseases with independent variables. Finally, the odds ratio along with a 95% confidence interval was used to report the significant association between the outcome variable and its associated factors. …”
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Detecting respiratory impairment in newly diagnosed rheumatoid arthritis by MRC dyspnoea scale and microfibrillar-associated protein 4 by Bjørk K. Sofiudottir, Sören Möller, Robin Christensen, Stefan Harders, Grith L. Sørensen, Jesper Blegvad, Mette Herly, Dzenan Masic, Grazina Urbonaviciene, Frank Andersen, Christin Isaksen, Brian Bridal Løgstrup, Charlotte Hyldgaard, Torkell Ellingsen

“…The primary outcomes were the MRC and MFAP4’s sensitivity, specificity, and diagnostic odds ratio (DOR) with 95% confidence intervals (CI).Results One hundred and thirty-one patients had available baseline tests. …”
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High serum uric acid levels are associated with increased prevalence of gallstones in adult women: a cross-sectional study based on NHANES by Guozheng Lv, Guozheng Lv, Decai Wang, Decai Wang, Yu Huang, Ruizi Shi, Chuan Qin, Xi Chen, Xintao Zeng, Hua Luo, Pei Yang, Sirui Chen, Jianjun Wang, Jianjun Wang

“…After adjusting for confounding, the prevalence of GS in adult women increased by 14% for every 1 mg/dL increase in SUA (odds ratio [OR]: 1.14, 95% confidence interval [CI]: 1.06, 1.22). …”
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Spinal pain prevalence and associated determinants: A population‐based study using the National Survey for Wales by David C. Byfield, Benjamin S. Stacey, Hywel T. Evans, Ian W. Farr, Leon Yandle, Lora Roberts, Teresa Filipponi, Damian M. Bailey

“…The strength of association between age and SP reaches its peak at 50–59 years with an adjusted Odds Ratio (aOR) of 3.74 (p = <0.001), that decreases slightly at 60–69 years and 70+ years. …”
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